ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Thompson CN, et al., 2015. Undifferentiated febrile illness in Kathmandu, Nepal. Am J Trop Med Hyg 92: 875–878.
-
2.
Dirección de Vigilancia y Análisis del Riesgo en Salud Pública Instituto Nacional deSalud (INS), 2015. Boletín Epidemiológico Semanal. Semana Epidemiológica Número 52 de 2015 (11 dic. al 02 ene.). Available at: http://www.ins.gov.co/boletin-epidemiologico/Boletn%20Epidemiolgico/2015%20Boletin%20epidemiologico%20Semana%2052.pdf. Accessed January 15, 2016.
-
3.
Patino L, Afanador A, Paul JH, 1937. A spotted fever in Tobia, Colombia. Am J Trop Med 17: 639–653.
-
4.
Patiño-Camargo L, 1941. Nuevas observaciones sobre un tercer foco de fiebre petequial (maculosa) en el hemisferio americano. Bol Of Sanit Panam (Engl) 20: 1112–1124.
-
5.
Hidalgo M, et al., 2007. Rocky Mountain spotted fever, Colombia. Emerg Infect Dis 13: 1058–1060.
-
6.
Hidalgo M, Sánchez R, Orejuela L, Hernández J, Walker DH, Valbuena G, 2007. Prevalence of antibodies against spotted fever group rickettsiae in a rural area of Colombia. Am J Trop Med Hyg 77: 378–380.
-
7.
Hidalgo M, Vesga JF, Lizarazo D, Valbuena G, 2009. A survey of antibodies against Rickettsia rickettsii and Ehrlichia chafeensis in domestic animals from a rural area of Colombia. Am J Trop Med Hyg 80: 1029–1030.
-
8.
Campos SDE, da Cunha NC, Almosny NRP, 2016. Brazilian spotted fever with an approach in veterinary medicine and One Health perspective. Vet Med Int 2016: 1–7.
-
9.
Eremeeva ME, Dasch GA, 2015. Challenges posed by tick-borne rickettsiae: eco-epidemiology and public health implications. Front Public Health 3: 55.
-
10.
Faccini-Martínez ÁA, Costa FB, Hayama-Ueno TE, Ramírez-Hernández A, Cortés-Vecino JA, Labruna M, 2015. Rickettsia rickettsii in Amblyomma patinoi ticks, Colombia. Emerg Infect Dis 21: 537–539.
-
11.
Faccini-Martínez ÁA, Gárcia-Álvarez L, Hidalgo M, Oteo JA, 2014. Syndromic classification of rickettsioses: an approach for clinical practice. Int J Infect Dis 28: 126–139.
-
12.
Hidalgo M, et al., 2013. Flea-borne rickettsioses in the North of Caldas Province, Colombia. Vector Borne Zoonotic Dis 13: 289–294.
-
13.
Barros-Battesti D, Arzua M, Bechara G, 2006. Carrapatos de Importância Médico-Veterinária da Região Neotropical: Um Guia Ilustrado para Identificação de Espécies. São Paulo, Brazil: International Consortium on Ticks and Tick-borne Diseases, 223.
-
14.
Martins TF, Onofrio VC, Barros-Battesti DM, Labruna M, 2010. Nymphs of the genus Amblyomma (Acari: Ixodidae) of Brazil: descriptions, redescriptions, and identification key. Ticks Tick Borne Dis 1: 75–99.
-
15.
Ramírez-Hernández A, et al., 2013. Molecular detection of Rickettsia felis in different flea species from Caldas, Colombia. Am J Trop Med Hyg 89: 453–459.
-
16.
Black WC, Piesman J, 1994. Phylogeny of hard- and soft-tick taxa (Acari: Ixodida) based on mitochondrial 16S rDNA sequences. Proc Natl Acad Sci USA 91: 10034–10038.
-
17.
Roux V, Fournier PE, Raoult D, 1996. Differentiation of spotted fever group rickettsiae by sequencing and analysis of restriction fragment length polymorphism of PCR-amplified DNA of the gene encoding the protein rOmpA. J Clin Microbiol 34: 2058–2065.
-
18.
Regnery RL, Spruill CL, Plikaytis BD, 1991. Genotypic identification of rickettsiae and estimation of intraspecies sequence divergence for portions of two rickettsial genes. J Bacteriol 173: 1576–1589.
-
19.
Choi YJ, Jang WJ, Ryu JS, Lee SH, Park KH, Paik HS, Koh YS, Choi MS, Kim IS, 2005. Spotted fever group and typhus group rickettsioses in humans, South Korea. Emerg Infect Dis 11: 237–244.
-
20.
Bello S, Rodríguez M, Paredes A, Mendivelso F, Walteros D, Rodríguez F, Realpe ME, 2013. Comportamiento de la vigilancia epidemiológica de leptospirosis humana en Colombia, 2007–2011. Biomedica 33: 153–160.
-
21.
Bharti AR, et al., 2003. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis 3: 757–771.
-
22.
Arroyave E, Londoño AF, Quintero JC, Agudelo-Flórez P, Arboleda M, Díaz FJ, Rodas JD, 2013. Etiología y caracterización epidemiológica del síndrome febril no palúdico en tres municipios del Urabá antioqueño, Colombia. Biomedica 33: 99–107.
-
23.
Acosta J, et al., 2006. Brote de rickettsiosis en Necoclí, Antioquia, febrero-marzo de 2006. Informe Quincenal Epidemiológico Nacional 11: 177–192.
-
24.
Pacheco-García OE, Giraldo MR, Hidalgo M, Galeano A, Echeverri I, Echavarría-Rodríguez L, Parra E, Rey G, 2008. Estudio de brote febril hemorrágico en el corregimiento de Alto de Mulatos: Distrito Especial Portuario de Turbo, Antioquia, enero de 2008. Informe Quincenal Epidemiológico Nacional 13: 145–160.
-
25.
Delisle J, Mendell NL, Stull-Lane A, Bloch KC, Bouyer DH, Moncayo AC, 2016. Human infections by multiple spotted fever group rickettsiae in Tennessee. Am J Trop Med Hyg 94: 1212–1217.
-
26.
Mattar S, Parra M, 2006. Detection of antibodies to Anaplasma, Bartonella, and Coxiella in rural inhabitants of the Caribbean area of Colombia. Rev MVZ Cordoba 11: 781–789.
-
27.
Rar V, Golovljova I, 2011. Anaplasma, Ehrlichia, and “Candidatus Neorhrlichia” bacteria: pathogenicity, biodiversity, and molecular genetic characteristics, a review. Infect Genet Evol 11: 1842–1861.
-
28.
Guglielmone AA, et al., 2006. Ticks (Ixodidae) on humans in South America. Exp Appl Acarol 40: 83–100.
-
29.
Santos HA, et al., 2013. Molecular epidemiology of the emerging zoonosis agent Anaplasma phagocytophilum (Foggie, 1949) in dogs and ixodid ticks in Brazil. Parasit Vectors 6: 348.
-
30.
Estrada-Peña A, Guglielmone AA, Mangold AJ, 2004. The distribution and ecological ‘preferences’ of the tick Amblyomma cajennense (Acari: Ixodidae), an ectoparasite of humans and other mammals. Ann Trop Med Parasitol 98: 283–292.
-
31.
Wells EA, D'Alessandro A, Morales GA, Angel D, 1981. Mammalian wildlife diseases as hazards to man and livestock in an area of the Llanos Orientales of Colombia. J Wildl Dis 17: 153–162.
-
32.
Paternina LE, Díaz-Olmos Y, Paternina-Gómez M, Bejarano EE, 2009. Canis familiaris, Un nuevo hospedero de Ornithodoros (A.) puertoricensis FOX, 1947 (Acari: Ixodida) en Colombia. Acta Biolo Colomb 14: 153–160.
-
33.
Londoño AF, Díaz FJ, Valbuena G, Gazi M, Labruna M, Hidalgo M, Mattar S, Contreras V, Rodas JD, 2014. Infection of Amblyomma ovale by Rickettsia sp. strain Atlantic rainforest, Colombia. Ticks Tick Borne Dis 5: 672–675.
-
34.
Miranda J, Portillo A, Oteo JA, Mattar S, 2012. Rickettsia sp. strain Colombianensi (Rickettsiales: Rickettsiaceae): a new proposed Rickettsia detected in Amblyomma dissimile (Acari: Ixodidae) from iguanas and free-living larvae ticks from vegetation. J Med Entomol 49: 960–965.
-
35.
Miranda J, Mattar S, 2014. Molecular detection of Rickettsia bellii and Rickettsia sp. strain Colombianensi in ticks from Cordoba, Colombia. Ticks Tick Borne Dis 5: 208–212.
-
36.
Faccini-Martínez ÁA, Ramírez-Hernández A, Forero-Becerra E, Cortés-Vecino JA, Escandón P, Rodas JD, Palomar AM, Portillo A, Oteo JA, Hidalgo M, 2016. Molecular evidence of different Rickettsia species in Villeta, Colombia. Vector Borne Zoonotic Dis 16: 85–87.
-
37.
Ramírez-Hernández A, Escandón P, Cortés-Vecino JA, Rodas JD, Hidalgo M, 2013. Detección molecular de Rickettsia spp. (Da Rocha-Lima, 1916) en garrapatas recolectadas en tres regiones de Colombia. Acta Med Costarric 55: 83–84.
-
38.
Bermúdez SE, Eremeeva ME, Karpathy SE, Samudio F, Zambrano ML, Zaldivar Y, Motta JA, Dasch GA, 2009. Detection and identification of rickettsial agents in ticks from domestic mammals in eastern Panama. J Med Entomol 46: 856–861.
-
39.
Merhej V, Angelakis E, Socolovschi C, Raoult D, 2014. Genotyping, evolution and epidemiological findings of Rickettsia species. Infect Genet Evol 25: 122–137.
-
40.
Monje LD, Costa FB, Colombo VC, Labruna MB, Antoniazzi LR, Gamietea I, Nava S, Beldomenico PM, 2016. Dynamics of exposure to Rickettsia parkeri in cattle in the Paraná River Delta, Argentina. J Med Entomol 53: 660–665.
-
41.
Pesquera C, Portillo A, Palomar AM, Oteo JA, 2015. Investigation of tick-borne bacteria (Rickettsia spp., Anaplasma spp., Ehrlichia spp. and Borrelia spp.) in ticks collected from Andean tapirs, cattle and vegetation from a protected area in Ecuador. Parasit Vectors 8: 46.
-
42.
Blanton LS, Mendell NL, Walker DH, Bouyer DH, 2014. “Rickettsia amblyommii” induces cross protection against lethal Rocky Mountain spotted fever in a guinea pig model. Vector Borne Zoonotic Dis 14: 557–562.
-
43.
Rivas JJ, Moreira-Soto A, Alvarado G, Taylor L, Calderón-Arguedas O, Hun L, Corrales-Aguilar E, Morales JA, Troyo A, 2015. Pathogenic potential of a Costa Rican strain of ‘Candidatus Rickettsia amblyommii’ in guinea pigs (Cavia porcellus) and protective immunity against Rickettsia rickettsii .Ticks Tick Borne Dis 6: 805–811.
-
44.
Walker DH, 2016. Changing dynamics of human-rickettsial interactions. Am J Trop Med Hyg 94: 3–4.
-
45.
Ogrzewalska M, Saraiva DG, Moraes-Filho J, Martins TF, Costa FB, Pinter A, Labruna MB, 2012. Epidemiology of Brazilian spotted fever in the Atlantic Forest, state of São Paulo, Brazil. Parasitology 139: 1283–1300.
-
46.
Wood CL, Lafferty KD, 2013. Biodiversity and disease: a synthesis of ecological perspectives on Lyme disease transmission. Trends Ecol Evol 28: 239–247.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 6 | 6 | 6 |
| Full Text Views | 539 | 188 | 6 |
| PDF Downloads | 315 | 105 | 6 |
Epidemiology of Spotted Fever Group Rickettsioses and Acute Undifferentiated Febrile Illness in Villeta, Colombia
Etiology of acute undifferentiated febrile syndrome (AUFS) is often unknown, leading to inaccurate diagnosis and treatment. Villeta town has been identified as an endemic area for spotted fever group (SFG) rickettsioses but little is known about possible amplifier hosts and other Rickettsia species different from Rickettsia rickettsii. Besides, few studies have approached other AUFS etiologies in the region. We investigated the role of dengue, leptospirosis, rickettsioses, human anaplasmosis, and Q fever as possible causes of AUFS in patients from Villeta. Sera specimens and ticks from animals as well as ticks from vegetation were studied for the presence of different Rickettsia spp. Among 104 sera from patients with AUFS, 16.4%, 24.0%, and 2.9% patients seroconverted to dengue, Leptospira, and SFG Rickettsia, respectively, with a case of probable coinfection or cross-reaction with Anaplasma phagocytophilum. None of the samples were reactive for Coxiella burnetii. Sera samples from 74 horses, 118 dogs, and 62 bovines were collected and showed 33.8%, 14.4%, and 50.0% of seroprevalence for SFG Rickettsia, respectively. A total of 1,287 ixodid ticks were collected from animals/vegetation and processed in pools for polymerase chain reaction. Among them, 1.7% was positive for Rickettsia genes, and Rickettsia amblyommii, R. rickettsii, and Rickettsia spp. were found. These results confirm the circulation of dengue, different SFG Rickettsia species and the relevance of other etiologies like leptospirosis and human anaplasmosis. Further studies must identify different epidemiological variables to establish proper surveillance and control programs.
Author Notes
Financial support: The study was supported by Departamento Administrativo de Ciencia, Tecnología e Innovación from Colombia (COLCIENCIAS, Code: 120351929098). Regulatory permits for this work were Permit in scientific research in biodiversity No. 005 of June 19, 2012, given by Corporación Autónoma Regional (CAR) de Cundinamarca and contract for access to genetic resources for scientific research without commercial interest No. 85 of 2013, given by Ministerio de Ambiente y Desarrollo Sostenible from Colombia.
Authors' addresses: Álvaro A. Faccini-Martínez, Programa de Pós-Graduação em Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, ES, Brazil, E-mail: afaccini@gmail.com. Alejandro Ramírez-Hernández, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, SP, Brazil, E-mail: aramirezhe@unal.edu.co. Christian Barreto, Diego Millán, Elkin Valbuena, Andrea C. Sánchez-Alfonso, and Marylin Hidalgo, Grupo de Enfermedades Infecciosas, Departamento de Microbiología, Pontificia Universidad Javeriana, Bogotá, Colombia, E-mails: davidbarreto_02@hotmail.com, dmillan19@hotmail.com, notengokorreo8@hotmail.com, asanchez-a@javeriana.edu.co, and hidalgo.m@javeriana.edu.co. Elkin Forero-Becerra, Departamento de Medicina Veterinária, Universidade Federal de Viçosa, Viçosa, MG, Brazil, E-mail: egforerob@unal.edu.co. Wilson O. Imbacuán-Pantoja and Jesús A. Cortés-Vecino, Grupo Parasitología Veterinaria, Universidad Nacional de Colombia, Ciudad Universitaria, Bogotá, Colombia, E-mails: woimbacuanp@unal.edu.co and jacortesv@unal.edu.co. Luis J. Polo-Terán and Néstor Yaya-Lancheros, Grupo Salud Pública Veterinaria, Departamento Salud Animal, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Bogotá, Colombia, E-mails: luijpolot@unal.edu.co and nyayal@unal.edu.co. Jorge Jácome, Departamento de Biología, Pontificia Universidad Javeriana, Bogotá, Colombia, E-mail: jacomej@javeriana.edu.co. Ana M. Palomar, Sonia Santibáñez, Aránzazu Portillo, and José A. Oteo, Infectious Diseases Department, Center of Rickettsioses and Arthropod-borne Diseases, Hospital San Pedro–CIBIR, Logroño, Spain, E-mails: ampalomar@riojasalud.es, ssantibanez@riojasalud.es aportillo@riojasalud.es, and jaoteo@riojasalud.es.