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Intestinal Parasitic Infections in Human Immunodeficiency Virus-Infected and Noninfected Persons in a High Human Immunodeficiency Virus Prevalence Region of Cameroon

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  • 1 Laboratory of Systems Biology, “Chantal Biya” International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon;
  • | 2 Department of Biological Sciences, Higher Teacher Training College, University of Yaounde I, Yaounde, Cameroon;
  • | 3 Molecular Biology Center, Yaounde, Cameroon;
  • | 4 Catholic University of Central Africa, School of Health Sciences, Yaounde, Cameroon;
  • | 5 Faculty of Sciences, University of Yaounde I, Yaounde, Cameroon;
  • | 6 Polytechnic School, University of Yaounde I, Yaounde, Cameroon;
  • | 7 California Pacific Medical Center, San Francisco, California
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The problem of intestinal parasitic infection in human immunodeficiency virus (HIV)–infected people requires careful consideration in the developing world where poor nutrition is associated with poor hygiene and several coinfecting diseases. Studies have addressed this issue in Cameroon, especially in the low HIV prevalence area. The current study was conducted to determine the prevalence of intestinal parasitosis in people living with HIV (PLHIV) in Adamaoua and to identify associated risk factors. Stool and blood specimens from study participants were screened for intestinal parasites and anti-HIV antibodies, respectively. Of 235 participants, 68 (28.9%) were HIV positive, 38 of them on antiretroviral treatment (ART). The overall prevalence of intestinal parasites was 32.3%. Of 68 PLHIV, 32.3% (22/68) were infected with intestinal parasites, compared with 32.3% (54/167) of the HIV-negative patients. Univariate analysis showed no difference between the prevalence of intestinal parasites among PLHIV and HIV-negative patients (P = 0.69). ART was not associated with the prevalence of intestinal parasites. Multivariate analysis showed that the quality of water and the personal hygiene were the major risk factors associated to intestinal parasitosis. The level of education was associated with HIV serostatus: the higher the level of education, the lower the risk of being infected with HIV (P = 0.00). PLHIV and the general population should be screened routinely for intestinal parasites and treated if infected.

Author Notes

Address correspondence to Céline Nguefeu Nkenfou, Laboratory of Systems Biology, “Chantal Biya” International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon. E-mail: nkenfou@yahoo.com

Authors’ addresses: Céline Nguefeu Nkenfou, Laboratory of Systems Biology, “Chantal Biya” International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon, Department of Biological Sciences, Higher Teacher Training College, University of Yaounde I, Yaounde, Cameroon, Molecular Biology Center, Yaounde, Cameroon, E-mail: nkenfou@yahoo.com. Sandrine Mboula Tchameni, Catholic University of Central Africa, School of Health Sciences, Yaounde, Cameroon, E-mail: sandysquat@yahoo.fr. Carine Nguefeu Nkenfou, Faculty of Sciences, University of Yaounde I, Yaounde, Cameroon, E-mail: nguefeucarine@yahoo.fr. Patrice Djataou, Molecular Biology Center, Yaounde, Cameroon, and Faculty of Sciences, University of Yaounde I, Yaounde, Cameroon, E-mail: djataouprince@yahoo.fr. Ulrich Florian Simo, Polytechnic School, University of Yaounde I, Yaounde, Cameroon, E-mail: florian_simo@yahoo.fr. Alexandre Benjamin Nkoum, Catholic University of Central Africa, School of Health Sciences, Yaounde, Cameroon, E-mail: benalexnkoum@yahoo.fr. William Estrin, California Pacific Medical Center, San Francisco, CA, E-mail: drbilestrin@hotmail.com.

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