HuongVT, HaN, HuyNT, HorbyP, NghiaHD, ThiemVD, ZhuX, HoaNT, HienTT, ZamoraJ, SchultszC, WertheimHF, HirayamaK, 2014. Epidemiology, clinical manifestations, and outcomes of Streptococcus suis infection in humans. Emerg Infect Dis20: 1105–1114.
HuongVTHaNHuyNTHorbyPNghiaHDThiemVDZhuXHoaNTHienTTZamoraJSchultszCWertheimHFHirayamaK, 2014. Epidemiology, clinical manifestations, and outcomes of Streptococcus suis infection in humans. Emerg Infect Dis20: 1105–1114.)| false
KerdsinA, DejsirilertS, PuangpatraP, SripakdeeS, ChumlaK, BoonkerdN, PolwichaiP, TanimuraS, TakeuchiD, NakayamaT, NakamuraS, AkedaY, GottschalkM, SawanpanyalertP, OishiK, 2011. Genotypic profile of Streptococcus suis serotype 2 and clinical features of infection in humans, Thailand. Emerg Infect Dis17: 835–842.
KerdsinADejsirilertSPuangpatraPSripakdeeSChumlaKBoonkerdNPolwichaiPTanimuraSTakeuchiDNakayamaTNakamuraSAkedaYGottschalkMSawanpanyalertPOishiK, 2011. Genotypic profile of Streptococcus suis serotype 2 and clinical features of infection in humans, Thailand. Emerg Infect Dis17: 835–842.)| false
TakeuchiD, KerdsinA, PienpringamA, LoetthongP, SamercheaS, LuangsukP, KhamisaraK, WongwanN, AreeratanaP, ChiranairadulP, LertchayantiS, PetcharatS, YowangA, ChaiwongsaenP, NakayamaT, AkedaY, HamadaS, SawanpanyalertP, DejsirilertS, OishiK, 2012. Population-based study of Streptococcus suis infection in humans in Phayao Province in northern Thailand. PLoS One7: e31265.
TakeuchiDKerdsinAPienpringamALoetthongPSamercheaSLuangsukPKhamisaraKWongwanNAreeratanaPChiranairadulPLertchayantiSPetcharatSYowangAChaiwongsaenPNakayamaTAkedaYHamadaSSawanpanyalertPDejsirilertSOishiK, 2012. Population-based study of Streptococcus suis infection in humans in Phayao Province in northern Thailand. PLoS One7: e31265.)| false
KhadthasrimaN, HannwongT, ThammawitjawaP, PingsuseanD, AkkanijB, JaikharA, PaungmaliP, YudeeP, WongyaiS, SamercheaS, TipsrirajS, PruksakornS, SutdanD, NoimohT, ChalamaatM, SamitsuwanP, ChuxnumT, AreechokchaiD, 2008. Human Streptococcus suis outbreak in Phayao Province, Thailand, 2007. OSIR1: 4–7.
KhadthasrimaNHannwongTThammawitjawaPPingsuseanDAkkanijBJaikharAPaungmaliPYudeePWongyaiSSamercheaSTipsrirajSPruksakornSSutdanDNoimohTChalamaatMSamitsuwanPChuxnumTAreechokchaiD, 2008. Human Streptococcus suis outbreak in Phayao Province, Thailand, 2007. OSIR1: 4–7.)| false
KerdsinA, OishiK, SripakdeeS, BoonkerdN, PolwichaiP, NakamuraS, UchidaR, SawanpanyalertP, DejsirilertS, 2009. Clonal dissemination of human isolates of Streptococcus suis serotype 14 in Thailand. J Med Microbiol58: 1508–1513.
KerdsinAOishiKSripakdeeSBoonkerdNPolwichaiPNakamuraSUchidaRSawanpanyalertPDejsirilertS, 2009. Clonal dissemination of human isolates of Streptococcus suis serotype 14 in Thailand. J Med Microbiol58: 1508–1513.)| false
Streptococcus suis is an important zoonotic pathogen in swine and humans that causes sepsis and meningitis. Our previous study in Thailand showed that the prevalence of S. suis infection in humans, especially in northern areas of Thailand, and the transmission of the pathogen occurred mainly through the consumption of traditional raw pork products. Considering the high incidence proportion and mortality rate of the disease as an important public health problem, we implemented a food safety campaign in the Phayao Province in northern Thailand in 2011. We evaluated the effects of a food safety campaign by comparing the sociodemographic, clinical, and bacteriological characteristics of cases before and after the campaign. The follow-up study showed a marked decrease of the incidence proportion in the first 2 years, indicating the effectiveness of the campaign. In the third year, however, the incidence proportion slightly increased again, indicating the existence of deep-rooted cultural behaviors and the necessity of continuous public health intervention. Furthermore, epidemiological analysis of the cases made it possible to estimate the infectivity of the pathogen via the oral route of infection. In the present study, we showed the effectiveness of the food safety campaign for controlling the S. suis infection, and we present a role model public health intervention for prevalent areas affected by S. suis infection in humans.
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* Address correspondence to Dan Takeuchi, Section of Bacterial Drug Resistance Research, Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, Japan 565-0871, E-mail: email@example.com or Yukihiro Akeda, Department of Infection Control and Prevention, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan 565-0871, E-mail: firstname.lastname@example.org.
Financial support: We thank the Department of Medical Sciences, Ministry of Public Health of Thailand, Japan Society for the Promotion of Science (KAKENHI 21406027), and Japan Initiative for a Global Research Network on Infectious Diseases launched by the Ministry of Education, Science, and Culture of Japan for providing financial support for this work.