ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Venkatswami S, Sankarasubramanian A, Subramanyam S, 2012. The madura foot: looking deep. Int J Low Extrem Wounds 11: 31–42.
-
2.
Lichon V, Khachemoune A, 2006. Mycetoma, a review. Am J Clin Dermatol 7: 315–321.
-
3.
Zijlstra EE, Van de Sande WWJ, Welsh O, Mahgoub ES, Goodfellow M, Fahal AH, 2016. Mycetoma: a unique neglected tropical disease. Lancet Infect Dis 16: 100–112.
-
4.
Nenoff P, Van de Sande WWJ, Fahal AH, Reinel D, Schöfer H, 2015. Eumycetoma and actinomycetoma: an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy. J Eur Acad Dermatol Venereol 29: 1873–1883.
-
5.
Buonfrate D, Gobbi F, Angheben A, Marocco S, Farina C, Van Den Ende J, Bisoffi Z, 2014. Autochthonous cases of mycetoma in Europe: report of two cases and review of literature. PLoS One 9: e100590.
-
6.
Rouphael NG, Talati NJ, Franco-Paredes C, 2007. A painful thorn in the foot: a case of eumycetoma. Am J Med Sci 334: 142–144.
-
7.
Foltz KD, Fallat LM, 2004. Madura foot: atypical finding and case presentation. J Foot Ankle Surg 43: 327–331.
-
8.
Dostrovsky A, Sagher F, 1942. Madura disease in Israel [in Hebrew]. Harefuah 13: 103–105.
-
9.
Dostrovsky A, Sagher F, 1948. Failure of sulphonamides and penicillin in maduromycosis. Lancet 1: 177–178.
-
10.
Dostrovsky A, Raubitschek KF, Sagher F, 1952. A case of black grain mycetoma caused by a Madurella species. Dermatologica 104: 415–423.
-
11.
Ziprkowsky L, Altmann G, Dalith F, Spitz U, 1957. Mycetoma pedis; four cases treated with streptomycin. AMA Arch Derm 75: 855–863.
-
12.
Schewach Millet M, Ziprkowski L, Feinstein A, Cvibah T, 1973. Mycetoma pedis, a report of two cases. Isr J Med Sci 9: 900–903.
-
13.
Alteras I, Feuerman EJ, Dayan I, 1980. Mycetoma due to Nocardia caviae. The first Israeli patient. Int J Dermatol 19: 260–262.
-
14.
Landau Z, Feld S, Frumkin A, Resnitzky P, 1986. Nocardia brasiliensis skin infections. Isr J Med Sci 22: 397–399.
-
15.
Alteras I, Feuerman EJ, 1986. The second case of mycetoma due to Nocardia caviae in Israel. Mycopathologia 93: 185–187.
-
16.
Alteras I, Abraham D, Ideses C, Segal R, Sandbank M, 1988. Mycetoma of the forearm due to Actinomadura madurae. Mycopathologia 103: 55–57.
-
17.
Alteras I, Hagler J, Trattner A, Morojinski G, Segal R, Sandbank M, 1992. Mycetoma with black granules: first case in a native of Israel [in German]. Hautarzt 43: 446–447.
-
18.
Tamir G, Adler A, Hagler J, Hauben DJ, Goldberg I, 1995. Mycetoma of the foot: surgical treatment with free flap reconstruction. Eur J Plast Surg 18: 124–126.
-
19.
Chazan B, Colodner R, Polacheck I, Shoufani A, Rozenman D, Raz R, 2004. Mycetoma of the foot caused by Cylindrocarpon lichenicola in an immunocompetent traveler. J Travel Med 11: 331–332.
-
20.
Brufman T, Ben-Ami R, Mizrahi M, Bash E, Paran Y, 2015. Mycetoma of the foot caused by Madurella mycetomatis in immigrants from Sudan. Isr Med Assoc J 17: 418–420.
-
21.
Raubitschek F, 1958. A critical survey of medical mycology in Israel 1946–1956. Mycopathol Mycol Appl 9: 176–182.
-
22.
Kuttin ES, Beemer AM, 1977. Systemic mycoses in Israel. Contrib Microbiol Immunol 4: 46–55.
-
24.
Schwartz E, Shpiro A, 2015. Madura foot or Philoctetes foot? Isr Med Assoc J 17: 442–444.
-
25.
Hershkovitz I, Speirs M, Katznelson A, Arensburg B, 1992. Unusual pathological condition in the lower extremities of a skeleton from ancient Israel. Am J Phys Anthropol 88: 23–26.
-
26.
Spigelman M, Donoghue HD, 2001. Brief communication: unusual pathological condition in the lower extremities of a skeleton from ancient Israel. Am J Phys Anthropol 114: 92–93.
-
27.
Clemow FG, 1906. Mycetoma (madura foot) in the Yemen. BMJ 1: 918–919.
-
28.
Yu AM, Zhao S, Nie LY, 1993. Mycetomas in northern Yemen: identification of causative organisms and epidemiologic considerations. Am J Trop Med Hyg 48: 812–817.
-
29.
Khatri ML, Al-Halali HM, Fouad Khalid M, Saif SA, Vyas MCR, 2002. Mycetoma in Yemen: clinicoepidemiologic and histopathologic study. Int J Dermatol 41: 586–593.
-
30.
Van De Sande WWJ, Vinetz JM, 2013. Global burden of human mycetoma: a systematic review and meta-analysis. PLoS Negl Trop Dis 7: e2550.
-
31.
The Israeli Central Bureau of Statistics, 2015. The Ethiopian Population in Israel [In Hebrew]. Available at: http://www.cbs.gov.il/reader/newhodaot/hodaa_template.html?hodaa=201511302. Accessed May 12, 2016.
-
32.
Israeli Authority of Immigration and Population, 2016. Reports of Foreigners in Israel [In Hebrew]. Available at: https://www.gov.il/he/Departments/publications/reports/foreign_workers_report_q1_2016. Accessed May 12, 2016.
-
33.
Fahal A, Sheikh Mahgoub E, El Hassan AM, Abdel-Rahman ME, 2015. Mycetoma in the Sudan: an update from the Mycetoma Research Centre, University of Khartoum, Sudan. PLoS Negl Trop Dis 9: e0003679.
-
34.
Pelzer K, Tietz HJ, Sterry W, Haas N, 2000. Isolation of both Sporothrix schenckii and Nocardia asteroides from a mycetoma of the forefoot. Br J Dermatol 143: 1311–1315.
-
35.
Douwes KE, Schmalzbauer E, Linde H-J, Reisberger EM, Fleischer K, Lehn N, Landthaler M, Vogt T, 2003. Branched filaments no fungus, ovoid bodies no bacteria: two unusual cases of mycetoma. J Am Acad Dermatol 49: S170–S173.
-
36.
Fletcher CL, Moore MK, Hay RJ, 2001. Eumycetoma due to Madurella mycetomatis acquired in Jamaica. Br J Dermatol 145: 1018–1021.
-
37.
Turner PG, 1989. Madura foot or plantar fibromatosis. J Bone Joint Surg Br 71: 531.
-
38.
Verdolini R, Amerio P, Bugatti L, Manso E, Cataldi I, Brancorsini D, Nicolini M, Filosa G, Giangioacomi M, 2000. Madura's foot: report of a case caused by Madurella mycetomatis. Eur J Dermatol 10: 627–629.
-
39.
Ichinomiya A, Nishimura K, Takenaka M, Utani A, Nishimoto K, 2014. Mycetoma caused by Nocardia transvalensis with repeated local recurrences for 25 years without dissemination to viscera. J Dermatol 41: 556–557.
-
40.
Van De Sande WWJ, Sheikh Maghoub E, Fahal AH, Goodfellow M, Welsh O, Zijlstra E, 2014. The mycetoma knowledge gap: identification of research priorities. PLoS Negl Trop Dis 8: e2667.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1499 | 1298 | 43 |
| Full Text Views | 747 | 14 | 0 |
| PDF Downloads | 312 | 16 | 0 |
Mycetoma (Madura Foot) in Israel: Recent Cases and a Systematic Review of the Literature
Ohad Bitan
Ohad Bitan
The Center for Geographic Medicine and Department of Medicine C, Sheba Medical Center, Ramat Gan, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Yonit Wiener-Well
Yonit Wiener-Well
Infectious Diseases Unit, Shaare-Zedek Medical Center, Jerusalem, Israel.
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Rina Segal
Rina Segal
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Dermatology, Rabin Medical Center, Petah Tikva, Israel.
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Department of Dermatology, Rabin Medical Center, Petah Tikva, Israel.
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Eli Schwartz
Eli Schwartz
The Center for Geographic Medicine and Department of Medicine C, Sheba Medical Center, Ramat Gan, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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PubMed
Mycetoma is a chronic soft tissue infection caused by fungal or bacterial pathogens, and is endemic in tropical and subtropical regions. Cases in developed countries outside the mycetoma belt are rare and usually imported by immigrants. Sporadic cases have been reported in Israel. Unpublished cases in the participating medical centers are reported. In addition, a systematic review of the literature was performed. All published mycetoma cases diagnosed in Israel were included with relevant variables collected. Twenty-one cases of mycetoma were diagnosed in Israel between 1942 and 2015, including four unpublished cases and 17 published cases. The mean age at diagnosis was 42 years (range 23–73), and 16 of the patients were male. The foot was the primary involved organ. Fifteen patients were immigrants from Yemen, Ethiopia, and Sudan. Five cases were autochthonous. One case was travel related. Among patients who developed symptoms after immigration, the mean time from exposure to symptom onset was 5.6 years (range 1–10 years). The mean time from symptom onset to diagnosis was 6.6 years (range 0.2–35 years). The autochthonous cases demonstrate that Israel is endemic of mycetoma. The immigrant population represents two distinct waves of immigration to Israel in the past century. Two unpublished cases of Ethiopian immigrants are the first reported cases of mycetoma acquired in Ethiopia. The diagnostic and therapeutic challenges along with the epidemiological data emphasize the need of raising the awareness of physicians to this devastating condition even in developed countries.
Author Notes
Authors' addresses: Ohad Bitan and Eli Schwartz, The Center for Geographic Medicine and Department of Medicine C, Sheba Medical Center, Ramat Gan, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, E-mails: ohad.bitan@gmail.com and elischwa@post.tau.ac.il. Yonit Wiener-Well, Infectious Diseases Unit, Shaare-Zedek Medical Center, Jerusalem, Israel, E-mail: yonitw@inter.net.il. Rina Segal, Department of Dermatology, Rabin Medical Center, Petah Tikva, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, E-mail: rinas3@clalit.org.il.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Venkatswami S, Sankarasubramanian A, Subramanyam S, 2012. The madura foot: looking deep. Int J Low Extrem Wounds 11: 31–42.
-
2.
Lichon V, Khachemoune A, 2006. Mycetoma, a review. Am J Clin Dermatol 7: 315–321.
-
3.
Zijlstra EE, Van de Sande WWJ, Welsh O, Mahgoub ES, Goodfellow M, Fahal AH, 2016. Mycetoma: a unique neglected tropical disease. Lancet Infect Dis 16: 100–112.
-
4.
Nenoff P, Van de Sande WWJ, Fahal AH, Reinel D, Schöfer H, 2015. Eumycetoma and actinomycetoma: an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy. J Eur Acad Dermatol Venereol 29: 1873–1883.
-
5.
Buonfrate D, Gobbi F, Angheben A, Marocco S, Farina C, Van Den Ende J, Bisoffi Z, 2014. Autochthonous cases of mycetoma in Europe: report of two cases and review of literature. PLoS One 9: e100590.
-
6.
Rouphael NG, Talati NJ, Franco-Paredes C, 2007. A painful thorn in the foot: a case of eumycetoma. Am J Med Sci 334: 142–144.
-
7.
Foltz KD, Fallat LM, 2004. Madura foot: atypical finding and case presentation. J Foot Ankle Surg 43: 327–331.
-
8.
Dostrovsky A, Sagher F, 1942. Madura disease in Israel [in Hebrew]. Harefuah 13: 103–105.
-
9.
Dostrovsky A, Sagher F, 1948. Failure of sulphonamides and penicillin in maduromycosis. Lancet 1: 177–178.
-
10.
Dostrovsky A, Raubitschek KF, Sagher F, 1952. A case of black grain mycetoma caused by a Madurella species. Dermatologica 104: 415–423.
-
11.
Ziprkowsky L, Altmann G, Dalith F, Spitz U, 1957. Mycetoma pedis; four cases treated with streptomycin. AMA Arch Derm 75: 855–863.
-
12.
Schewach Millet M, Ziprkowski L, Feinstein A, Cvibah T, 1973. Mycetoma pedis, a report of two cases. Isr J Med Sci 9: 900–903.
-
13.
Alteras I, Feuerman EJ, Dayan I, 1980. Mycetoma due to Nocardia caviae. The first Israeli patient. Int J Dermatol 19: 260–262.
-
14.
Landau Z, Feld S, Frumkin A, Resnitzky P, 1986. Nocardia brasiliensis skin infections. Isr J Med Sci 22: 397–399.
-
15.
Alteras I, Feuerman EJ, 1986. The second case of mycetoma due to Nocardia caviae in Israel. Mycopathologia 93: 185–187.
-
16.
Alteras I, Abraham D, Ideses C, Segal R, Sandbank M, 1988. Mycetoma of the forearm due to Actinomadura madurae. Mycopathologia 103: 55–57.
-
17.
Alteras I, Hagler J, Trattner A, Morojinski G, Segal R, Sandbank M, 1992. Mycetoma with black granules: first case in a native of Israel [in German]. Hautarzt 43: 446–447.
-
18.
Tamir G, Adler A, Hagler J, Hauben DJ, Goldberg I, 1995. Mycetoma of the foot: surgical treatment with free flap reconstruction. Eur J Plast Surg 18: 124–126.
-
19.
Chazan B, Colodner R, Polacheck I, Shoufani A, Rozenman D, Raz R, 2004. Mycetoma of the foot caused by Cylindrocarpon lichenicola in an immunocompetent traveler. J Travel Med 11: 331–332.
-
20.
Brufman T, Ben-Ami R, Mizrahi M, Bash E, Paran Y, 2015. Mycetoma of the foot caused by Madurella mycetomatis in immigrants from Sudan. Isr Med Assoc J 17: 418–420.
-
21.
Raubitschek F, 1958. A critical survey of medical mycology in Israel 1946–1956. Mycopathol Mycol Appl 9: 176–182.
-
22.
Kuttin ES, Beemer AM, 1977. Systemic mycoses in Israel. Contrib Microbiol Immunol 4: 46–55.
-
24.
Schwartz E, Shpiro A, 2015. Madura foot or Philoctetes foot? Isr Med Assoc J 17: 442–444.
-
25.
Hershkovitz I, Speirs M, Katznelson A, Arensburg B, 1992. Unusual pathological condition in the lower extremities of a skeleton from ancient Israel. Am J Phys Anthropol 88: 23–26.
-
26.
Spigelman M, Donoghue HD, 2001. Brief communication: unusual pathological condition in the lower extremities of a skeleton from ancient Israel. Am J Phys Anthropol 114: 92–93.
-
27.
Clemow FG, 1906. Mycetoma (madura foot) in the Yemen. BMJ 1: 918–919.
-
28.
Yu AM, Zhao S, Nie LY, 1993. Mycetomas in northern Yemen: identification of causative organisms and epidemiologic considerations. Am J Trop Med Hyg 48: 812–817.
-
29.
Khatri ML, Al-Halali HM, Fouad Khalid M, Saif SA, Vyas MCR, 2002. Mycetoma in Yemen: clinicoepidemiologic and histopathologic study. Int J Dermatol 41: 586–593.
-
30.
Van De Sande WWJ, Vinetz JM, 2013. Global burden of human mycetoma: a systematic review and meta-analysis. PLoS Negl Trop Dis 7: e2550.
-
31.
The Israeli Central Bureau of Statistics, 2015. The Ethiopian Population in Israel [In Hebrew]. Available at: http://www.cbs.gov.il/reader/newhodaot/hodaa_template.html?hodaa=201511302. Accessed May 12, 2016.
-
32.
Israeli Authority of Immigration and Population, 2016. Reports of Foreigners in Israel [In Hebrew]. Available at: https://www.gov.il/he/Departments/publications/reports/foreign_workers_report_q1_2016. Accessed May 12, 2016.
-
33.
Fahal A, Sheikh Mahgoub E, El Hassan AM, Abdel-Rahman ME, 2015. Mycetoma in the Sudan: an update from the Mycetoma Research Centre, University of Khartoum, Sudan. PLoS Negl Trop Dis 9: e0003679.
-
34.
Pelzer K, Tietz HJ, Sterry W, Haas N, 2000. Isolation of both Sporothrix schenckii and Nocardia asteroides from a mycetoma of the forefoot. Br J Dermatol 143: 1311–1315.
-
35.
Douwes KE, Schmalzbauer E, Linde H-J, Reisberger EM, Fleischer K, Lehn N, Landthaler M, Vogt T, 2003. Branched filaments no fungus, ovoid bodies no bacteria: two unusual cases of mycetoma. J Am Acad Dermatol 49: S170–S173.
-
36.
Fletcher CL, Moore MK, Hay RJ, 2001. Eumycetoma due to Madurella mycetomatis acquired in Jamaica. Br J Dermatol 145: 1018–1021.
-
37.
Turner PG, 1989. Madura foot or plantar fibromatosis. J Bone Joint Surg Br 71: 531.
-
38.
Verdolini R, Amerio P, Bugatti L, Manso E, Cataldi I, Brancorsini D, Nicolini M, Filosa G, Giangioacomi M, 2000. Madura's foot: report of a case caused by Madurella mycetomatis. Eur J Dermatol 10: 627–629.
-
39.
Ichinomiya A, Nishimura K, Takenaka M, Utani A, Nishimoto K, 2014. Mycetoma caused by Nocardia transvalensis with repeated local recurrences for 25 years without dissemination to viscera. J Dermatol 41: 556–557.
-
40.
Van De Sande WWJ, Sheikh Maghoub E, Fahal AH, Goodfellow M, Welsh O, Zijlstra E, 2014. The mycetoma knowledge gap: identification of research priorities. PLoS Negl Trop Dis 8: e2667.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1499 | 1298 | 43 |
| Full Text Views | 747 | 14 | 0 |
| PDF Downloads | 312 | 16 | 0 |