- Finding the Correct Diagnosis for Acute Febrile Illness Matters
- Traditional Microbiology Techniques Reinvent Themselves
- Nucleic Acid Amplification Tests are Becoming Easier to Use
- Metagenomic Sequencing Can Identify Any Pathogen
- New Molecular Techniques are Not Perfect
- Put It On Paper, or On a Chip, and Throw Away the Needle
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Van Hemelrijck MJ, Lindblade KA, Kubaje A, Hamel MJ, Odhiambo F, Phillips-Howard PA, Laserson KF, Slutsker L, Feikin DR, 2009. Trends observed during a decade of paediatric sick visits to peripheral health facilities in rural western Kenya, 1997–2006. Trop Med Int Health 14: 62–69.
-
2.
Salvi S, Apte K, Madas S, Barne M, Chhowala S, Sethi T, Aggarwal K, Agrawal A, Gogtay J, 2015. Symptoms and medical conditions in 204 912 patients visiting primary health-care practitioners in India: a 1-day point prevalence study (the POSEIDON study). Lancet Glob Health 3: e776–e784.
-
3.
Crump JA, Kirk MD, 2015. Estimating the burden of febrile illnesses. PLoS Negl Trop Dis 9: e0004040.
-
4.
GBD 2013 DALYs and HALE Collaborators, Murray CJ, Barber RM, Foreman KJ, Abbasoglu Ozgoren A, Abd-Allah F, Abera SF, Aboyans V, Abraham JP, Abubakar I, Abu-Raddad LJ, Abu-Rmeileh NM, Achoki T, Ackerman IN, Ademi Z, Adou AK, Adsuar JC, Afshin A, Agardh EE, Alam SS, Alasfoor D, Albittar MI, Alegretti MA, Alemu ZA, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allebeck P, Almazroa MA, Alsharif U, Alvarez E, Alvis-Guzman N, Amare AT, Ameh EA, Amini H, Ammar W, Anderson HR, Anderson BO, Antonio CA, Anwari P, Arnlov J, Arsic Arsenijevic VS, Artaman A, Asghar RJ, Assadi R, Atkins LS, Avila MA, Awuah B, Bachman VF, Badawi A, Bahit MC, Balakrishnan K, Banerjee A, Barker-Collo SL, Barquera S, Barregard L, Barrero LH, Basu A, Basu S, Basulaiman MO, Beardsley J, Bedi N, Beghi E, Bekele T, Bell ML, Benjet C, Bennett DA, Bensenor IM, Benzian H, Bernabe E, Bertozzi-Villa A, Beyene TJ, Bhala N, Bhalla A, Bhutta ZA, Bienhoff K, Bikbov B, Biryukov S, Blore JD, Blosser CD, Blyth FM, Bohensky MA, Bolliger IW, Bora Basara B, Bornstein NM, Bose D, Boufous S, Bourne RR, Boyers LN, Brainin M, Brayne CE, Brazinova A, Breitborde NJ, Brenner H, Briggs AD, Brooks PM, Brown JC, Brugha TS, Buchbinder R, Buckle GC, Budke CM, Bulchis A, Bulloch AG, Campos-Nonato IR, Carabin H, Carapetis JR, Cárdenas R, Carpenter DO, Caso V, Castañeda-Orjuela CA, Castro RE, Catalá-López F, Cavalleri F, Çavlin A, Chadha VK, Chang JC, Charlson FJ, Chen H, Chen W, Chiang PP, Chimed-Ochir O, Chowdhury R, Christensen H, Christophi CA, Cirillo M, Coates MM, Coffeng LE, Coggeshall MS, Colistro V, Colquhoun SM, Cooke GS, Cooper C, Cooper LT, Coppola LM, Cortinovis M, Criqui MH, Crump JA, Cuevas-Nasu L, Danawi H, Dandona L, Dandona R, Dansereau E, Dargan PI, Davey G, Davis A, Davitoiu DV, Dayama A, De Leo D, Degenhardt L, Del Pozo-Cruz B, Dellavalle RP, Deribe K, Derrett S, Des Jarlais DC, Dessalegn M, Dharmaratne SD, Dherani MK, Diaz-Torné C, Dicker D, Ding EL, Dokova K, Dorsey ER, Driscoll TR, Duan L, Duber HC, Ebel BE, Edmond KM, Elshrek YM, Endres M, Ermakov SP, Erskine HE, Eshrati B, Esteghamati A, Estep K, Faraon EJ, Farzadfar F, Fay DF, Feigin VL, Felson DT, Fereshtehnejad SM, Fernandes JG, Ferrari AJ, Fitzmaurice C, Flaxman AD, Fleming TD, Foigt N, Forouzanfar MH, Fowkes FG, Paleo UF, Franklin RC, Fürst T, Gabbe B, Gaffikin L, Gankpé FG, Geleijnse JM, Gessner BD, Gething P, Gibney KB, Giroud M, Giussani G, Gomez Dantes H, Gona P, González-Medina D, Gosselin RA, Gotay CC, Goto A, Gouda HN, Graetz N, Gugnani HC, Gupta R, Gupta R, Gutiérrez RA, Haagsma J, Hafezi-Nejad N, Hagan H, Halasa YA, Hamadeh RR, Hamavid H, Hammami M, Hancock J, Hankey GJ, Hansen GM, Hao Y, Harb HL, Haro JM, Havmoeller R, Hay SI, Hay RJ, Heredia-Pi IB, Heuton KR, Heydarpour P, Higashi H, Hijar M, Hoek HW, Hoffman HJ, Hosgood HD, Hossain M, Hotez PJ, Hoy DG, Hsairi M, Hu G, Huang C, Huang JJ, Husseini A, Huynh C, Iannarone ML, Iburg KM, Innos K, Inoue M, Islami F, Jacobsen KH, Jarvis DL, Jassal SK, Jee SH, Jeemon P, Jensen PN, Jha V, Jiang G, Jiang Y, Jonas JB, Juel K, Kan H, Karch A, Karema CK, Karimkhani C, Karthikeyan G, Kassebaum NJ, Kaul A, Kawakami N, Kazanjan K, Kemp AH, Kengne AP, Keren A, Khader YS, Khalifa SE, Khan EA, Khan G, Khang YH, Kieling C, Kim D, Kim S, Kim Y, Kinfu Y, Kinge JM, Kivipelto M, Knibbs LD, Knudsen AK, Kokubo Y, Kosen S, Krishnaswami S, Kuate Defo B, Kucuk Bicer B, Kuipers EJ, Kulkarni C, Kulkarni VS, Kumar GA, Kyu HH, Lai T, Lalloo R, Lallukka T, Lam H, Lan Q, Lansingh VC, Larsson A, Lawrynowicz AE, Leasher JL, Leigh J, Leung R, Levitz CE, Li B, Li Y, Li Y, Lim SS, Lind M, Lipshultz SE, Liu S, Liu Y, Lloyd BK, Lofgren KT, Logroscino G, Looker KJ, Lortet-Tieulent J, Lotufo PA, Lozano R, Lucas RM, Lunevicius R, Lyons RA, Ma S, Macintyre MF, Mackay MT, Majdan M, Malekzadeh R, Marcenes W, Margolis DJ, Margono C, Marzan MB, Masci JR, Mashal MT, Matzopoulos R, Mayosi BM, Mazorodze TT, Mcgill NW, Mcgrath JJ, Mckee M, Mclain A, Meaney PA, Medina C, Mehndiratta MM, Mekonnen W, Melaku YA, Meltzer M, Memish ZA, Mensah GA, Meretoja A, Mhimbira FA, Micha R, Miller TR, Mills EJ, Mitchell PB, Mock CN, Mohamed Ibrahim N, Mohammad KA, Mokdad AH, Mola GL, Monasta L, Montañez Hernandez JC, Montico M, Montine TJ, Mooney MD, Moore AR, Moradi-Lakeh M, Moran AE, Mori R, Moschandreas J, Moturi WN, Moyer ML, Mozaffarian D, Msemburi WT, Mueller UO, Mukaigawara M, Mullany EC, Murdoch ME, Murray J, Murthy KS, Naghavi M, Naheed A, Naidoo KS, Naldi L, Nand D, Nangia V, Narayan KM, Nejjari C, Neupane SP, Newton CR, Ng M, Ngalesoni FN, Nguyen G, Nisar MI, Nolte S, Norheim OF, Norman RE, Norrving B, Nyakarahuka L, Oh IH, Ohkubo T, Ohno SL, Olusanya BO, Opio JN, Ortblad K, Ortiz A, Pain AW, Pandian JD, Panelo CI, Papachristou C, Park EK, Park JH, Patten SB, Patton GC, Paul VK, Pavlin BI, Pearce N, Pereira DM, Perez-Padilla R, Perez-Ruiz F, Perico N, Pervaiz A, Pesudovs K, Peterson CB, Petzold M, Phillips MR, Phillips BK, Phillips DE, Piel FB, Plass D, Poenaru D, Polinder S, Pope D, Popova S, Poulton RG, Pourmalek F, Prabhakaran D, Prasad NM, Pullan RL, Qato DM, Quistberg DA, Rafay A, Rahimi K, Rahman SU, Raju M, Rana SM, Razavi H, Reddy KS, Refaat A, Remuzzi G, Resnikoff S, Ribeiro AL, Richardson L, Richardus JH, Roberts DA, Rojas-Rueda D, Ronfani L, Roth GA, Rothenbacher D, Rothstein DH, Rowley JT, Roy N, Ruhago GM, Saeedi MY, Saha S, Sahraian MA, Sampson UK, Sanabria JR, Sandar L, Santos IS, Satpathy M, Sawhney M, Scarborough P, Schneider IJ, Schöttker B, Schumacher AE, Schwebel DC, Scott JG, Seedat S, Sepanlou SG, Serina PT, Servan-Mori EE, Shackelford KA, Shaheen A, Shahraz S, Shamah Levy T, Shangguan S, She J, Sheikhbahaei S, Shi P, Shibuya K, Shinohara Y, Shiri R, Shishani K, Shiue I, Shrime MG, Sigfusdottir ID, Silberberg DH, Simard EP, Sindi S, Singh A, Singh JA, Singh L, Skirbekk V, Slepak EL, Sliwa K, Soneji S, Søreide K, Soshnikov S, Sposato LA, Sreeramareddy CT, Stanaway JD, Stathopoulou V, Stein DJ, Stein MB, Steiner C, Steiner TJ, Stevens A, Stewart A, Stovner LJ, Stroumpoulis K, Sunguya BF, Swaminathan S, Swaroop M, Sykes BL, Tabb KM, Takahashi K, Tandon N, Tanne D, Tanner M, Tavakkoli M, Taylor HR, Te Ao BJ, Tediosi F, Temesgen AM, Templin T, Ten Have M, Tenkorang EY, Terkawi AS, Thomson B, Thorne-Lyman AL, Thrift AG, Thurston GD, Tillmann T, Tonelli M, Topouzis F, Toyoshima H, Traebert J, Tran BX, Trillini M, Truelsen T, Tsilimbaris M, Tuzcu EM, Uchendu US, Ukwaja KN, Undurraga EA, Uzun SB, Van Brakel WH, Van De Vijver S, van Gool CH, Van Os J, Vasankari TJ, Venketasubramanian N, Violante FS, Vlassov VV, Vollset SE, Wagner GR, Wagner J, Waller SG, Wan X, Wang H, Wang J, Wang L, Warouw TS, Weichenthal S, Weiderpass E, Weintraub RG, Wenzhi W, Werdecker A, Westerman R, Whiteford HA, Wilkinson JD, Williams TN, Wolfe CD, Wolock TM, Woolf AD, Wulf S, Wurtz B, Xu G, Yan LL, Yano Y, Ye P, Yentür GK, Yip P, Yonemoto N, Yoon SJ, Younis MZ, Yu C, Zaki ME, Zhao Y, Zheng Y, Zonies D, Zou X, Salomon JA, Lopez AD, Vos T, 2015. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition. Lancet 386: 2145–2191.
-
5.
Institute for Health Metrics and Evaluation (IHME), 2015. GBD Compare. Available at: http://vizhub.healthdata.org/gbd-compare. Accessed August 1, 2016.
-
6.
Punjabi NH, Taylor WR, Murphy GS, Purwaningsih S, Picarima H, Sisson J, Olson JG, Baso S, Wangsasaputra F, Lesmana M, Oyofo BA, Simanjuntak CH, Subekti D, Corwin AL, Richie TL, 2012. Etiology of acute, non-malaria, febrile illnesses in Jayapura, northeastern Papua, Indonesia. Am J Trop Med Hyg 86: 46–51.
-
7.
Crump JA, Morrissey AB, Nicholson WL, Massung RF, Stoddard RA, Galloway RL, Ooi EE, Maro VP, Saganda W, Kinabo GD, Muiruri C, Bartlett JA, 2013. Etiology of severe non-malaria febrile illness in northern Tanzania: a prospective cohort study. PLoS Negl Trop Dis 7: e2324.
-
8.
D'Acremont V, Kilowoko M, Kyungu E, Philipina S, Sangu W, Kahama-Maro J, Lengeler C, Cherpillod P, Kaiser L, Genton B, 2014. Beyond malaria–causes of fever in outpatient Tanzanian children. N Engl J Med 370: 809–817.
-
9.
Mayxay M, Castonguay-Vanier J, Chansamouth V, Dubot-Peres A, Paris DH, Phetsouvanh R, Tangkhabuanbutra J, Douangdala P, Inthalath S, Souvannasing P, Slesak G, Tongyoo N, Chanthongthip A, Panyanouvong P, Sibounheuang B, Phommasone K, Dohnt M, Phonekeo D, Hongvanthong B, Xayadeth S, Ketmayoon P, Blacksell SD, Moore CE, Craig SB, Burns MA, von Sonnenburg F, Corwin A, de Lamballerie X, Gonzalez IJ, Christophel EM, Cawthorne A, Bell D, Newton PN, 2013. Causes of non-malarial fever in Laos: a prospective study. Lancet Glob Health 1: e46–e54.
-
10.
Chheng K, Carter MJ, Emary K, Chanpheaktra N, Moore CE, Stoesser N, Putchhat H, Sona S, Reaksmey S, Kitsutani P, Sar B, van Doorn HR, Uyen NH, Van Tan L, Paris D, Blacksell SD, Amornchai P, Wuthiekanun V, Parry CM, Day NPJ, Kumar V, 2013. A prospective study of the causes of febrile illness requiring hospitalization in children in Cambodia. PLoS One 8: e60634.
-
11.
Mueller TC, Siv S, Khim N, Kim S, Fleischmann E, Ariey F, Buchy P, Guillard B, González IJ, Christophel E-M, Abdur R, von Sonnenburg F, Bell D, Menard D, 2014. Acute undifferentiated febrile illness in rural Cambodia: a 3-year prospective observational study. PLoS One 9: e95868.
-
12.
Manock SR, Jacobsen KH, de Bravo NB, Russell KL, Negrete M, Olson JG, Sanchez JL, Blair PJ, Smalligan RD, Quist BK, Espin JF, Espinoza WR, MacCormick F, Fleming LC, Kochel T, 2009. Etiology of acute undifferentiated febrile illness in the Amazon basin of Ecuador. Am J Trop Med Hyg 81: 146–151.
-
13.
Kasper MR, Blair PJ, Touch S, Sokhal B, Yasuda CY, Williams M, Richards AL, Burgess TH, Wierzba TF, Putnam SD, 2012. Infectious etiologies of acute febrile illness among patients seeking health care in south-central Cambodia. Am J Trop Med Hyg 86: 246–253.
-
14.
Rubach MP, Maro VP, Bartlett JA, Crump JA, 2015. Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy. Am J Trop Med Hyg 92: 454–462.
-
15.
Bassat Q, Machevo S, O'Callaghan-Gordo C, Sigauque B, Morais L, Diez-Padrisa N, Ribo JL, Mandomando I, Nhampossa T, Ayala E, Sanz S, Weber M, Roca A, Alonso PL, 2011. Distinguishing malaria from severe pneumonia among hospitalized children who fulfilled integrated management of childhood illness criteria for both diseases: a hospital-based study in Mozambique. Am J Trop Med Hyg 85: 626–634.
-
16.
Laxminarayan R, Matsoso P, Pant S, Brower C, Rottingen JA, Klugman K, Davies S, 2016. Access to effective antimicrobials: a worldwide challenge. Lancet 387: 168–175.
-
17.
Holman RC, Paddock CD, Curns AT, Krebs JW, McQuiston JH, Childs JE, 2001. Analysis of risk factors for fatal Rocky Mountain Spotted Fever: evidence for superiority of tetracyclines for therapy. J Infect Dis 184: 1437–1444.
-
18.
Yasunaga H, Horiguchi H, Kuwabara K, Hashimoto H, Matsuda S, 2011. Delay in tetracycline treatment increases the risk of complications in Tsutsugamushi disease: data from the Japanese Diagnosis Procedure Combination database. Intern Med 50: 37–42.
-
19.
Prabhu M, Nicholson WL, Roche AJ, Kersh GJ, Fitzpatrick KA, Oliver LD, Massung RF, Morrissey AB, Bartlett JA, Onyango JJ, Maro VP, Kinabo GD, Saganda W, Crump JA, 2011. Q fever, spotted fever group, and typhus group rickettsioses among hospitalized febrile patients in northern Tanzania. Clin Infect Dis 53: e8–e15.
-
20.
Dittrich S, Rattanavong S, Lee SJ, Panyanivong P, Craig SB, Tulsiani SM, Blacksell SD, Dance DAB, Dubot-Pérès A, Sengduangphachanh A, Phoumin P, Paris DH, Newton PN, 2015. Orientia, Rickettsia, and leptospira pathogens as causes of CNS infections in Laos: a prospective study. Lancet Glob Health 3: e104–e112.
-
21.
Jacob ST, Pavlinac PB, Nakiyingi L, Banura P, Baeten JM, Morgan K, Magaret A, Manabe Y, Reynolds SJ, Liles WC, Wald A, Joloba ML, Mayanja-Kizza H, Scheld WM, 2013. Mycobacterium tuberculosis bacteremia in a cohort of HIV-infected patients hospitalized with severe sepsis in Uganda–high frequency, low clinical sand derivation of a clinical prediction score. PLoS One 8: e70305.
-
22.
Chandy SJ, Thomas K, Mathai E, Antonisamy B, Holloway KA, Stalsby Lundborg C, 2013. Patterns of antibiotic use in the community and challenges of antibiotic surveillance in a lower-middle-income country setting: a repeated cross-sectional study in Vellore, south India. J Antimicrob Chemother 68: 229–236.
-
23.
Elfving K, Shakely D, Andersson M, Baltzell K, Ali AS, Bachelard M, Falk KI, Ljung A, Msellem MI, Omar RS, Parola P, Xu W, Petzold M, Trollfors B, Björkman A, Lindh M, Mårtensson A, 2016. Acute uncomplicated febrile illness in children aged 2–59 months in Zanzibar—aetiologies, antibiotic treatment and outcome. PLoS One 11: e0146054.
-
24.
Juma E, Zurovac D, 2011. Changes in health workers' malaria diagnosis and treatment practices in Kenya. Malar J 10: 1.
-
25.
Batwala V, Magnussen P, Nuwaha F, 2011. Antibiotic use among patients with febrile illness in a low malaria endemicity setting in Uganda. Malar J 10: 377.
-
26.
Holloway KA, Rosella L, Henry D, 2016. The impact of WHO essential medicines policies on inappropriate use of antibiotics. PLoS One 11: e0152020.
-
27.
Brink AJ, Messina AP, Feldman C, Richards GA, Becker PJ, Goff DA, Bauer KA, Nathwani D, van den Bergh D; Netcare Antimicrobial Stewardship Study Alliance, 2016. Antimicrobial stewardship across 47 South African hospitals: an implementation study. Lancet Infect Dis 16: 1017–1025.
-
28.
Čižman M, 2003. The use and resistance to antibiotics in the community. Int J Antimicrob Agents 21: 297–307.
-
29.
Chatterjee D, Sen S, Begum SA, Adhikari A, Hazra A, Das AK, 2015. A questionnaire-based survey to ascertain the views of clinicians regarding rational use of antibiotics in teaching hospitals of Kolkata. Indian J Pharmacol 47: 105–108.
-
30.
D'Acremont V, Kahama-Maro J, Swai N, Mtasiwa D, Genton B, Lengeler C, 2011. Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study. Malar J 10: 107.
-
31.
Ndhlovu M, Nkhama E, Miller JM, Hamer DH, 2015. Antibiotic prescribing practices for patients with fever in the transition from presumptive treatment of malaria to ‘confirm and treat’ in Zambia: a cross-sectional study. Trop Med Int Health 20: 1696–1706.
-
32.
Ssekabira U, Bukirwa H, Hopkins H, Namagembe A, Weaver MR, Sebuyira LM, Quick L, Staedke S, Yeka A, Kiggundu M, Schneider G, McAdam K, Wabwire-Mangen F, Dorsey G, 2008. Improved malaria case management after integrated team-based training of health care workers in Uganda. Am J Trop Med Hyg 79: 826–833.
-
33.
Moon AM, Biggs HM, Rubach MP, Crump JA, Maro VP, Saganda W, Reddy EA, 2014. Evaluation of in-hospital management for febrile illness in northern Tanzania before and after 2010 World Health Organization Guidelines for the treatment of malaria. PLoS One 9: e89814.
-
34.
Joshi R, Colford JM Jr, Reingold AL, Kalantri S, 2008. Nonmalarial acute undifferentiated fever in a rural hospital in central India: diagnostic uncertainty and overtreatment with antimalarial agents. Am J Trop Med Hyg 78: 393–399.
-
35.
Reyburn H, Mbakilwa H, Mwangi R, Mwerinde O, Olomi R, Drakeley C, Whitty CJM, 2007. Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial. BMJ 334: 403.
-
36.
Hamer DH, Ndhlovu M, Zurovac D, Fox M, Yeboah-Antwi K, Chanda P, Sipilinyambe N, Simon JL, Snow RW, 2007. Improved diagnostic testing and malaria treatment practices in Zambia. JAMA 297: 2227–2231.
-
37.
Sudhinaraset M, Ingram M, Lofthouse HK, Montagu D, 2013. What is the role of informal healthcare providers in developing countries? A systematic review. PLoS One 8: e54978.
-
38.
Ocan M, Manabe YC, Baluku H, Atukwase E, Ogwal-Okeng J, Obua C, 2015. Prevalence and predictors of prior antibacterial use among patients presenting to hospitals in northern Uganda. BMC Pharmacol Toxicol 16: 26.
-
39.
Alsan M, Schoemaker L, Eggleston K, Kammili N, Kolli P, Bhattacharya J, 2015. Out-of-pocket health expenditures and antimicrobial resistance in low-income and middle-income countries: an economic analysis. Lancet Infect Dis 15: 1203–1210.
-
40.
Goossens H, Ferech M, Stichele RV, Elseviers M, ESAC Project Group, 2005. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 365: 579–587.
-
41.
Holmes AH, Moore LS, Sundsfjord A, Steinbakk M, Regmi S, Karkey A, Guerin PJ, Piddock LJ, 2016. Understanding the mechanisms and drivers of antimicrobial resistance. Lancet 387: 176–187.
-
42.
Van Boeckel TP, Gandra S, Ashok A, Caudron Q, Grenfell BT, Levin SA, Laxminarayan R, 2014. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis 14: 742–750.
-
43.
Castanheira M, Farrell SE, Krause KM, Jones RN, Sader HS, 2014. Contemporary diversity of beta-lactamases among Enterobacteriaceae in the nine U.S. census regions and ceftazidime-avibactam activity tested against isolates producing the most prevalent beta-lactamase groups. Antimicrob Agents Chemother 58: 833–838.
-
44.
Morens DM, Fauci AS, 2013. Emerging infectious diseases: threats to human health and global stability. PLoS Pathog 9: e1003467.
-
45.
Faria NR, Azevedo RSS, Kraemer MUG, Souza R, Cunha MS, Hill SC, Thézé J, Bonsall MB, Bowden TA, Rissanen I, Rocco IM, Nogueira JS, Maeda AY, Vasami FG, Macedo FL, Suzuki A, Rodrigues SG, Cruz ACR, Nunes BT, Medeiros DB, Rodrigues DSG, Nunes Queiroz AL, da Silva EVP, Henriques DF, Travassos da Rosa ES, de Oliveira CS, Martins LC, Vasconcelos HB, Casseb LMN, Simith D de B, Messina JP, Abade L, Lourenço J, Alcantara LCJ, de Lima MM, Giovanetti M, Hay SI, de Oliveira RS, Lemos P da S, Oliveira LF, de Lima CPS, da Silva SP, Vasconcelos JM, Franco L, Cardoso JF, Vianez-Júnior JL, Mir D, Bello G, Delatorre E, Khan K, Creatore M, Coelho GE, de Oliveira WK, Tesh R, Pybus OG, Nunes MRT, Vasconcelos PFC, 2016. Zika virus in the Americas: early epidemiological and genetic findings. Science 352: 345–349.
-
46.
Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N, Soropogui B, Sow MS, Keita S, De Clerck H, Tiffany A, Dominguez G, Loua M, Traore A, Kolie M, Malano ER, Heleze E, Bocquin A, Mely S, Raoul H, Caro V, Cadar D, Gabriel M, Pahlmann M, Tappe D, Schmidt-Chanasit J, Impouma B, Diallo AK, Formenty P, Van Herp M, Gunther S, 2014. Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med 371: 1418–1425.
-
47.
Dixon MG, Schafer IJ; Centers for Disease Control Prevention, 2014. Ebola viral disease outbreak–west Africa, 2014. MMWR Morb Mortal Wkly Rep 63: 548–551.
-
48.
Dhillon RS, Srikrishna D, Garry RF, Chowell G, 2015. Ebola control: rapid diagnostic testing. Lancet Infect Dis 15: 147–148.
-
49.
Lewnard JA, Ndeffo Mbah ML, Alfaro-Murillo JA, Altice FL, Bawo L, Nyenswah TG, Galvani AP, 2014. Dynamics and control of Ebola virus transmission in Montserrado, Liberia: a mathematical modelling analysis. Lancet Infect Dis 14: 1189–1195.
-
50.
Henao-Restrepo AM, Longini IM, Egger M, Dean NE, Edmunds WJ, Camacho A, Carroll MW, Doumbia M, Draguez B, Duraffour S, Enwere G, Grais R, Gunther S, Hossmann S, Konde MK, Kone S, Kuisma E, Levine MM, Mandal S, Norheim G, Riveros X, Soumah A, Trelle S, Vicari AS, Watson CH, Keita S, Kieny MP, Rottingen JA, 2015. Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. Lancet 386: 857–866.
-
51.
Slater HC, Ross A, Ouedraogo AL, White LJ, Nguon C, Walker PGT, Ngor P, Aguas R, Silal SP, Dondorp AM, La Barre P, Burton R, Sauerwein RW, Drakeley C, Smith TA, Bousema T, Ghani AC, 2015. Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies. Nature 528: S94–S101.
-
52.
Andrews JR, Prajapati KG, Eypper E, Shrestha P, Shakya M, Pathak KR, Joshi N, Tiwari P, Risal M, Koirala S, Karkey A, Dongol S, Wen S, Smith AB, Maru D, Basnyat B, Baker S, Farrar J, Ryan ET, Hohmann E, Arjyal A, 2013. Evaluation of an electricity-free, culture-based approach for detecting typhoidal Salmonella bacteremia during enteric fever in a high burden, resource-limited setting. PLoS Negl Trop Dis 7: e2292.
-
53.
D'Ambrosio MV, Bakalar M, Bennuru S, Reber C, Skandarajah A, Nilsson L, Switz N, Kamgno J, Pion S, Boussinesq M, Nutman TB, Fletcher DA, 2015. Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope. Sci Transl Med 7: 286re4.
-
54.
Pirnstill CW, Coté GL, 2015. Malaria diagnosis using a mobile phone polarized microscope. Sci Rep 5: 13368.
-
55.
Lukianova-Hleb EY, Campbell KM, Constantinou PE, Braam J, Olson JS, Ware RE, Sullivan DJ Jr, Lapotko DO, 2014. Hemozoin-generated vapor nanobubbles for transdermal reagent- and needle-free detection of malaria. Proc Natl Acad Sci USA 111: 900–905.
-
56.
Ekaterina L-H, Sarah B, Reka S, Alexander K, Thomas K, Andrew H, Michail B, Nirbhay K, Umberto DA, Dmitri L, 2015. Transdermal diagnosis of malaria using vapor nanobubbles. Emerg Infect Dis 21: 1122.
-
57.
Bisser S, Lumbala C, Nguertoum E, Kande V, Flevaud L, Vatunga G, Boelaert M, Büscher P, Josenando T, Bessell PR, Biéler S, Ndung'u JM, 2016. Sensitivity and specificity of a prototype rapid diagnostic test for the detection of Trypanosoma brucei gambiense infection: a multi-centric prospective study. PLoS Negl Trop Dis 10: e0004608.
-
58.
Xu GJ, Kula T, Xu Q, Li MZ, Vernon SD, Ndung'u T, Ruxrungtham K, Sanchez J, Brander C, Chung RT, O'Connor KC, Walker B, Larman HB, Elledge SJ, 2015. Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome. Science 348 (6239): aaa0698.
-
59.
Jung JH, Lee JE, 2016. Real-time bacterial microcolony counting using on-chip microscopy. Sci Rep 6: 21473.
-
60.
Leung K, Zahn H, Leaver T, Konwar KM, Hanson NW, Pagé AP, Lo C-C, Chain PS, Hallam SJ, Hansen CL, 2012. A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities. Proc Natl Acad Sci USA 109: 7665–7670.
-
61.
Shemesh J, Ben Arye T, Avesar J, Kang JH, Fine A, Super M, Meller A, Ingber DE, Levenberg S, 2014. Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis. Proc Natl Acad Sci USA 111: 11293–11298.
-
62.
Choi J, Yoo J, Lee M, Kim EG, Lee JS, Lee S, Joo S, Song SH, Kim EC, Lee JC, Kim HC, Jung YG, Kwon S, 2014. A rapid antimicrobial susceptibility test based on single-cell morphological analysis. Sci Transl Med 6: 267ra174.
-
63.
Lee J, Armstrong DT, Ssengooba W, Park J-a, Yu Y, Mumbowa F, Namaganda C, Mboowa G, Nakayita G, Armakovitch S, Chien G, Cho S-N, Via LE, Barry CE, Ellner JJ, Alland D, Dorman SE, Joloba ML, 2014. Sensititre MYCOTB MIC plate for testing Mycobacterium tuberculosis susceptibility to first- and second-line drugs. Antimicrob Agents Chemother 58: 11–18.
-
64.
Laksanasopin T, Guo TW, Nayak S, Sridhara AA, Xie S, Olowookere OO, Cadinu P, Meng F, Chee NH, Kim J, Chin CD, Munyazesa E, Mugwaneza P, Rai AJ, Mugisha V, Castro AR, Steinmiller D, Linder V, Justman JE, Nsanzimana S, Sia SK, 2015. A smartphone dongle for diagnosis of infectious diseases at the point of care. Sci Transl Med 7: 273re1.
-
65.
Park TS, Li W, McCracken KE, Yoon J-Y, 2013. Smartphone quantifies Salmonella from paper microfluidics. Lab Chip 13: 4832–4840.
-
66.
Bristow CC, Leon SR, Ramos LB, Vargas SK, Flores JA, Konda KA, Caceres CF, Klausner JD, 2015. Laboratory evaluation of a dual rapid immunodiagnostic test for HIV and syphilis infection. J Clin Microbiol 53: 311–313.
-
67.
Herbst de Cortina S, Bristow CC, Vargas SK, Perez DG, Konda KA, Caceres CF, Klausner JD, 2016. Laboratory evaluation of a point-of-care downward-flow assay for simultaneous detection of antibodies to Treponema pallidum and human immunodeficiency virus. J Clin Microbiol 54: 1922–1924.
-
68.
Leon SR, Ramos LB, Vargas SK, Kojima N, Perez DG, Caceres CF, Klausner JD, 2016. Laboratory evaluation of a dual-path platform assay for rapid point-of-care HIV and syphilis testing. J Clin Microbiol 54: 492–494.
-
69.
Deraney RN, Mace CR, Rolland JP, Schonhorn JE, 2016. Multiplexed, patterned-paper immunoassay for detection of malaria and dengue fever. Anal Chem 88: 6161–6165.
-
70.
Gao C-h, Yang Y-t, Shi F, Wang J-y, Steverding D, Wang X, 2015. Development of an immunochromatographic test for diagnosis of visceral leishmaniasis based on detection of a circulating antigen. PLoS Negl Trop Dis 9: e0003902.
-
71.
FIND, 2016. Negotiated Product Pricing. Available at: http://www.finddx.org/find-negotiated-product-pricing/. Accessed December 16, 2016.
-
72.
World Health Organization, 2011. Visceral Leishmaniasis Rapid Diagnostic Test Performance. Available at: http://www.who.int/tdr/publications/documents/vl-rdt-evaluation.pdf. Accessed December 19, 2016.
-
73.
Baron EJ, Miller JM, Weinstein MP, Richter SS, Gilligan PH, Thomson RB Jr, Bourbeau P, Carroll KC, Kehl SC, Dunne WM, Robinson-Dunn B, Schwartzman JD, Chapin KC, Snyder JW, Forbes BA, Patel R, Rosenblatt JE, Pritt BS, 2013. A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM). Clin Infect Dis 57: e22–e121.
-
74.
Piepenburg O, Williams CH, Stemple DL, Armes NA, 2006. DNA detection using recombination proteins. PLoS Biol 4: e204.
-
75.
Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T, 2000. Loop-mediated isothermal amplification of DNA. Nucleic Acids Res 28: e63.
-
76.
Guatelli JC, Whitfield KM, Kwoh DY, Barringer KJ, Richman DD, Gingeras TR, 1990. Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication. Proc Natl Acad Sci USA 87: 1874–1878.
-
77.
Crannell ZA, Rohrman B, Richards-Kortum R, 2014. Equipment-free incubation of recombinase polymerase amplification reactions using body heat. PLoS One 9: e112146.
-
78.
Nie S, Roth RB, Stiles J, Mikhlina A, Lu X, Tang YW, Babady NE, 2014. Evaluation of Alere i Influenza A and B for rapid detection of influenza viruses A and B. J Clin Microbiol 52: 3339–3344.
-
79.
Fisher Scientific, Alere i Influenza A and B. Available at: https://www.fishersci.com/shop/products/alere-i-influenza-a-b-3/p-4898455. Accessed July 19, 2016.
-
80.
Buss SN, Leber A, Chapin K, Fey PD, Bankowski MJ, Jones MK, Rogatcheva M, Kanack KJ, Bourzac KM, 2015. Multicenter evaluation of the BioFire FilmArray gastrointestinal panel for etiologic diagnosis of infectious gastroenteritis. J Clin Microbiol 53: 915–925.
-
81.
Leber AL, Everhart K, Balada-Llasat JM, Cullison J, Daly J, Holt S, Lephart P, Salimnia H, Schreckenberger PC, DesJarlais S, Reed SL, Chapin KC, LeBlanc L, Johnson JK, Soliven NL, Carroll K, Miller JA, Dien Bard J, Mestas J, Bankowski M, Enomoto T, Hemmert AC, Bourzac K, 2016. Multicenter evaluation of the BioFire FilmArray meningitis encephalitis panel for the detection of bacteria, ciruses and yeast in cerebrospinal fluid specimens. J Clin Microbiol 54: 2251–2261.
-
82.
Nelson RE, Stockmann C, Hersh AL, Pavia AT, Korgenksi K, Daly JA, Couturier MR, Ampofo K, Thorell EA, Doby EH, Robison JA, Blaschke AJ, 2015. Economic analysis of rapid and sensitive polymerase chain reaction testing in the emergency department for influenza infections in children. Pediatr Infect Dis J 34: 577–582.
-
83.
Xu M, Qin X, Astion ML, Rutledge JC, Simpson J, Jerome KR, Englund JA, Zerr DM, Migita RT, Rich S, Childs JC, Cent A, Del Beccaro MA, 2013. Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care. Am J Clin Pathol 139: 118–123.
-
84.
Weller SA, Bailey D, Matthews S, Lumley S, Sweed A, Ready D, Eltringham G, Richards J, Vipond R, Lukaszewski R, Payne PM, Aarons E, Simpson AJ, Hutley EJ, Brooks T, 2016. Evaluation of the Biofire FilmArray BioThreat-E Test (v2.5) for rapid identification of Ebola virus disease in heat-treated blood samples obtained in Sierra Leone and the United Kingdom. J Clin Microbiol 54: 114–119.
-
85.
Castan P, de Pablo A, Fernandez-Romero N, Rubio JM, Cobb BD, Mingorance J, Toro C, 2014. Point-of-care system for detection of Mycobacterium tuberculosis and rifampin resistance in sputum samples. J Clin Microbiol 52: 502–507.
-
86.
Shenai S, Armstrong DT, Valli E, Dolinger DL, Nakiyingi L, Dietze R, Dalcolmo MP, Nicol MP, Zemanay W, Manabe Y, Hadad DJ, Marques-Rodrigues P, Palaci M, Peres RL, Gaeddert M, Armakovitch S, Nonyane BA, Denkinger CM, Banada P, Joloba ML, Ellner J, Boehme C, Alland D, Dorman SE, 2016. Analytical and clinical evaluation of the Epistem Genedrive assay for detection of Mycobacterium tuberculosis. J Clin Microbiol 54: 1051–1057.
-
87.
Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, Allen J, Tahirli R, Blakemore R, Rustomjee R, Milovic A, Jones M, O'Brien SM, Persing DH, Ruesch-Gerdes S, Gotuzzo E, Rodrigues C, Alland D, Perkins MD, 2010. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med 363: 1005–1015.
-
88.
Semper AE, Broadhurst MJ, Richards J, Foster GM, Simpson AJH, Logue CH, Kelly JD, Miller A, Brooks TJG, Murray M, Pollock NR, 2016. Performance of the GeneXpert Ebola assay for diagnosis of Ebola virus disease in Sierra Leone: a field evaluation study. PLoS Med 13: e1001980.
-
89.
Van den Bergh R, Chaillet P, Sow MS, Amand M, van Vyve C, Jonckheere S, Crestani R, Sprecher A, Van Herp M, Chua A, Piriou E, Koivogui L, Antierens A, 2016. Feasibility of Xpert Ebola assay in Medecins Sans Frontieres ebola program, Guinea. Emerg Infect Dis 22: 210–216.
-
90.
Pantoja A, Kik SV, Denkinger CM, 2015. Costs of novel tuberculosis diagnostics–will countries be able to afford it? J Infect Dis 211 (Suppl 2): S67–S77.
-
91.
Wahrenbrock MG, Matushek S, Boonlayangoor S, Tesic V, Beavis KG, Charnot-Katsikas A, 2016. Comparison of Cepheid Xpert Flu/RSV XC and BioFire FilmArray for detection of influenza A, influenza B, and respiratory syncytial virus. J Clin Microbiol 54: 1902–1903.
-
92.
Gonzalez MD, Langley LC, Buchan BW, Faron ML, Maier M, Templeton K, Walker K, Popowitch EB, Miller MB, Rao A, Liebert UG, Ledeboer NA, Vinje J, Burnham CA, 2016. Multicenter evaluation of the Xpert norovirus assay for detection of norovirus genogroups I and II in fecal specimens. J Clin Microbiol 54: 142–147.
-
93.
Kurosaki Y, Magassouba NF, Oloniniyi OK, Cherif MS, Sakabe S, Takada A, Hirayama K, Yasuda J, 2016. Development and evaluation of reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assay coupled with a portable device for rapid diagnosis of Ebola virus disease in Guinea. PLoS Negl Trop Dis 10: e0004472.
-
94.
Patel JC, Lucchi NW, Srivastava P, Lin JT, Sug-Aram R, Aruncharus S, Bharti PK, Shukla MM, Congpuong K, Satimai W, Singh N, Udhayakumar V, Meshnick SR, 2014. Field evaluation of a real-time fluorescence loop-mediated isothermal amplification assay, RealAmp, for the diagnosis of malaria in Thailand and India. J Infect Dis 210: 1180–1187.
-
95.
Lu X, Li X, Mo Z, Jin F, Wang B, Zhao H, Shan X, Shi L, 2012. Rapid identification of chikungunya and dengue virus by a real-time reverse transcription-loop-mediated isothermal amplification method. Am J Trop Med Hyg 87: 947–953.
-
96.
Dittrich S, Castonguay-Vanier J, Moore CE, Thongyoo N, Newton PN, Paris DH, 2014. Loop-mediated isothermal amplification for Rickettsia typhi (the causal agent of murine typhus): problems with diagnosis at the limit of detection. J Clin Microbiol 52: 832–838.
-
97.
Kubo T, Agoh M, Mai LQ, Fukushima K, Nishimura H, Yamaguchi A, Hirano M, Yoshikawa A, Hasebe F, Kohno S, Morita K, 2010. Development of a reverse transcription-loop-mediated isothermal amplification assay for detection of pandemic (H1N1) 2009 virus as a novel molecular method for diagnosis of pandemic influenza in resource-limited settings. J Clin Microbiol 48: 728–735.
-
98.
Fukuda S, Takao S, Kuwayama M, Shimazu Y, Miyazaki K, 2006. Rapid detection of norovirus from fecal specimens by real-time reverse transcription-loop-mediated isothermal amplification assay. J Clin Microbiol 44: 1376–1381.
-
99.
Lee D, Kim EJ, Kilgore PE, Kim SA, Takahashi H, Ohnishi M, Anh DD, Dong BQ, Kim JS, Tomono J, Miyamoto S, Notomi T, Kim DW, Seki M, 2015. Clinical evaluation of a loop-mediated isothermal amplification (LAMP) assay for rapid detection of Neisseria meningitidis in cerebrospinal fluid. PLoS One 10: e0122922.
-
100.
Nagai K, Horita N, Yamamoto M, Tsukahara T, Nagakura H, Tashiro K, Shibata Y, Watanabe H, Nakashima K, Ushio R, Ikeda M, Narita A, Kanai A, Sato T, Kaneko T, 2016. Diagnostic test accuracy of loop-mediated isothermal amplification assay for Mycobacterium tuberculosis: systematic review and meta-analysis. Sci Rep 6: 39090.
-
101.
Greninger AL, Naccache SN, Federman S, Yu G, Mbala P, Bres V, Bouquet J, Stryke D, Somasekar S, Linnen J, Dodd R, Mulembakani P, Schneider B, Muyembe J-J, Stramer S, Chiu CY, 2015. Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis. Genome Med 7: 99.
-
102.
Hoenen T, Groseth A, Rosenke K, Fischer RJ, Hoenen A, Judson SD, Martellaro C, Falzarano D, Marzi A, Squires RB, Wollenberg KR, de Wit E, Prescott J, Safronetz D, van Doremalen N, Bushmaker T, Feldmann F, McNally K, Bolay FK, Fields B, Sealy T, Rayfield M, Nichol ST, Zoon KC, Massaquoi M, Munster VJ, Feldmann H, 2016. Nanopore Sequencing as a rapidly deployable Ebola outbreak tool. Emerg Infect Dis 22: 331.
-
103.
Quick J, Loman NJ, Duraffour S, Simpson JT, Severi E, Cowley L, Bore JA, Koundouno R, Dudas G, Mikhail A, Ouédraogo N, Afrough B, Bah A, Baum JHJ, Becker-Ziaja B, Boettcher JP, Cabeza-Cabrerizo M, Camino-Sánchez Á, Carter LL, Doerrbecker J, Enkirch T, Dorival IG, Hetzelt N, Hinzmann J, Holm T, Kafetzopoulou LE, Koropogui M, Kosgey A, Kuisma E, Logue CH, Mazzarelli A, Meisel S, Mertens M, Michel J, Ngabo D, Nitzsche K, Pallasch E, Patrono LV, Portmann J, Repits JG, Rickett NY, Sachse A, Singethan K, Vitoriano I, Yemanaberhan RL, Zekeng EG, Racine T, Bello A, Sall AA, Faye O, Faye O, Magassouba NF, Williams CV, Amburgey V, Winona L, Davis E, Gerlach J, Washington F, Monteil V, Jourdain M, Bererd M, Camara A, Somlare H, Camara A, Gerard M, Bado G, Baillet B, Delaune D, Nebie KY, Diarra A, Savane Y, Pallawo RB, Gutierrez GJ, Milhano N, Roger I, Williams CJ, Yattara F, Lewandowski K, Taylor J, Rachwal P, Turner DJ, Pollakis G, Hiscox JA, Matthews DA, Shea MKO, Johnston AM, Wilson D, Hutley E, Smit E, Di Caro A, Wölfel R, Stoecker K, Fleischmann E, Gabriel M, Weller SA, Koivogui L, Diallo B, Keïta S, Rambaut A, Formenty P, Günther S, Carroll MW, 2016. Real-time, portable genome sequencing for Ebola surveillance. Nature 530: 228–232.
-
104.
Oxford Nanopore Technologies, 2016. Everything Nanopore: MinION, PromethION, Kits and Consumables. Available at: https://store.nanoporetech.com/. Accessed December 16, 2016.
-
105.
Yehia N, Arafa AS, Abd El Wahed A, El-Sanousi AA, Weidmann M, Shalaby MA, 2015. Development of reverse transcription recombinase polymerase amplification assay for avian influenza H5N1 HA gene detection. J Virol Methods 223: 45–49.
-
106.
Chao C-C, Belinskaya T, Zhang Z, Ching W-M, 2015. Development of recombinase polymerase amplification assays for detection of Orientia tsutsugamushi or Rickettsia typhi. PLoS Negl Trop Dis 9: e0003884.
-
107.
Abd El Wahed A, Patel P, Faye O, Thaloengsok S, Heidenreich D, Matangkasombut P, Manopwisedjaroen K, Sakuntabhai A, Sall AA, Hufert FT, Weidmann M, 2015. Recombinase polymerase amplification assay for rapid diagnostics of dengue infection. PLoS One 10: e0129682.
-
108.
Yang M, Ke Y, Wang X, Ren H, Liu W, Lu H, Zhang W, Liu S, Chang G, Tian S, Wang L, Huang L, Liu C, Yang R, Chen Z, 2016. Development and evaluation of a rapid and sensitive EBOV-RPA test for rapid diagnosis of Ebola virus disease. Sci Rep 6: 26943.
-
109.
Boyle DS, McNerney R, Teng Low H, Leader BT, Pérez-Osorio AC, Meyer JC, O'Sullivan DM, Brooks DG, Piepenburg O, Forrest MS, 2014. Rapid detection of Mycobacterium tuberculosis by recombinase polymerase amplification. PLoS One 9: e103091.
-
110.
Crannell ZA, Cabada MM, Castellanos-Gonzalez A, Irani A, White AC, Richards-Kortum R, 2015. Recombinase polymerase amplification-based assay to diagnose Giardia in stool samples. Am J Trop Med Hyg 92: 583–587.
-
111.
Liu J, Ochieng C, Wiersma S, Stroher U, Towner JS, Whitmer S, Nichol ST, Moore CC, Kersh GJ, Kato C, Sexton C, Petersen J, Massung R, Hercik C, Crump JA, Kibiki G, Maro A, Mujaga B, Gratz J, Jacob ST, Banura P, Scheld WM, Juma B, Onyango CO, Montgomery JM, Houpt E, Fields B, 2016. Development of a TaqMan Array Card for acute-febrile-illness outbreak investigation and surveillance of emerging pathogens, including Ebola virus. J Clin Microbiol 54: 49–58.
-
112.
Kodani M, Yang G, Conklin LM, Travis TC, Whitney CG, Anderson LJ, Schrag SJ, Taylor TH, Beall BW, Breiman RF, Feikin DR, Njenga MK, Mayer LW, Oberste MS, Tondella MLC, Winchell JM, Lindstrom SL, Erdman DD, Fields BS, 2011. Application of TaqMan low-density arrays for simultaneous detection of multiple respiratory pathogens. J Clin Microbiol 49: 2175–2182.
-
113.
Liu J, Gratz J, Amour C, Kibiki G, Becker S, Janaki L, Verweij JJ, Taniuchi M, Sobuz SU, Haque R, Haverstick DM, Houpt ER, 2013. A laboratory-developed TaqMan Array Card for simultaneous detection of 19 enteropathogens. J Clin Microbiol 51: 472–480.
-
114.
Marx V, 2015. PCR heads into the field. Nat Methods 12: 393–397.
-
115.
Pardee K, Green AA, Takahashi MK, Braff D, Lambert G, Lee JW, Ferrante T, Ma D, Donghia N, Fan M, Daringer NM, Bosch I, Dudley DM, O'Connor DH, Gehrke L, Collins JJ, 2016. Rapid, low-cost detection of Zika virus using programmable biomolecular components. Cell 165: 1255–1266.
-
116.
Hopkins H, González IJ, Polley SD, Angutoko P, Ategeka J, Asiimwe C, Agaba B, Kyabayinze DJ, Sutherland CJ, Perkins MD, Bell D, 2013. Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda. J Infect Dis 208: 645–652.
-
117.
Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH, 2015. Analytical performance characteristics of the Cepheid GeneXpert Ebola assay for the detection of Ebola virus. PLoS One 10: e0142216.
-
118.
Theron G, Zijenah L, Chanda D, Clowes P, Rachow A, Lesosky M, Bara W, Mungofa S, Pai M, Hoelscher M, Dowdy D, Pym A, Mwaba P, Mason P, Peter J, Dheda K; TB-NEAT Team, 2014. Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial. Lancet 383: 424–435.
-
119.
Evans CA, 2011. GeneXpert—a game-changer for tuberculosis control? PLoS Med 8: e1001064.
-
120.
Drain PK, Garrett NJ, 2015. The arrival of a true point-of-care molecular assay-ready for global implementation? Lancet Glob Health 3: e663–e664.
-
121.
Mölsä M, Koskela KA, Rönkkö E, Ikonen N, Ziegler T, Nikkari S, 2012. Detection of influenza A viruses with a portable real-time PCR instrument. J Virol Methods 181: 188–191.
-
122.
Matero P, Hemmila H, Tomaso H, Piiparinen H, Rantakokko-Jalava K, Nuotio L, Nikkari S, 2011. Rapid field detection assays for Bacillus anthracis, Brucella spp., Francisella tularensis and Yersinia pestis. Clin Microbiol Infect 17: 34–43.
-
123.
Waggoner JJ, Gresh L, Mohamed-Hadley A, Ballesteros G, Davila MJ, Tellez Y, Sahoo MK, Balmaseda A, Harris E, Pinsky BA, 2016. Single-reaction multiplex reverse transcription PCR for detection of Zika, chikungunya, and dengue viruses. Emerg Infect Dis 22: 1295–1297.
-
124.
Centers for Disease Control and Prevention, 2016. Trioplex Real-Time RT-PCR Assay: Instructions for Use. Available at: http://www.fda.gov/downloads/MedicalDevices/Safety/EmergencySituations/UCM491592.pdf. Accessed July 15, 2016.
-
125.
Sharp SE, Hill CE, Valsamakis A, 2016. ASM, AMP and PASCV Express Concerns on New Molecular Test for Zika. Available at: http://www.asm.org/index.php/whatsnew-policy/137-policy/documents/statements-and-testimony/94652-zika-test-10-16. Accessed December 6, 2016.
-
126.
Glushakova LG, Bradley A, Bradley KM, Alto BW, Hoshika S, Hutter D, Sharma N, Yang Z, Kim MJ, Benner SA, 2015. High-throughput multiplexed xMAP Luminex array panel for detection of twenty two medically important mosquito-borne arboviruses based on innovations in synthetic biology. J Virol Methods 214: 60–74.
-
127.
Barzon L, Lavezzo E, Costanzi G, Franchin E, Toppo S, Palu G, 2013. Next-generation sequencing technologies in diagnostic virology. J Clin Virol 58: 346–350.
-
128.
Graf EH, Simmon KE, Tardif KD, Hymas W, Flygare S, Eilbeck K, Yandell M, Schlaberg R, 2016. Unbiased detection of respiratory viruses by use of RNA sequencing-based metagenomics: a systematic comparison to a commercial PCR panel. J Clin Microbiol 54: 1000–1007.
-
129.
Sardi S, Somasekar S, Naccache SN, Bandeira AC, Tauro LB, Campos GS, Chiu CY, 2016. Co-infections from Zika and chikungunya virus in Bahia, Brazil identified by metagenomic next-generation sequencing. J Clin Microbiol 54: 2348–2353.
-
130.
Yozwiak NL, Skewes-Cox P, Stenglein MD, Balmaseda A, Harris E, DeRisi JL, 2012. Virus identification in unknown tropical febrile illness cases using deep sequencing. PLoS Negl Trop Dis 6: e1485.
-
131.
Wilson MR, Naccache SN, Samayoa E, Biagtan M, Bashir H, Yu G, Salamat SM, Somasekar S, Federman S, Miller S, Sokolic R, Garabedian E, Candotti F, Buckley RH, Reed KD, Meyer TL, Seroogy CM, Galloway R, Henderson SL, Gern JE, DeRisi JL, Chiu CY, 2014. Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med 370: 2408–2417.
-
132.
McMullan LK, Folk SM, Kelly AJ, MacNeil A, Goldsmith CS, Metcalfe MG, Batten BC, Albarino CG, Zaki SR, Rollin PE, Nicholson WL, Nichol ST, 2012. A new phlebovirus associated with severe febrile illness in Missouri. N Engl J Med 367: 834–841.
-
133.
Stremlau MH, Andersen KG, Folarin OA, Grove JN, Odia I, Ehiane PE, Omoniwa O, Omoregie O, Jiang PP, Yozwiak NL, Matranga CB, Yang X, Gire SK, Winnicki S, Tariyal R, Schaffner SF, Okokhere PO, Okogbenin S, Akpede GO, Asogun DA, Agbonlahor DE, Walker PJ, Tesh RB, Levin JZ, Garry RF, Sabeti PC, Happi CT, 2015. Discovery of novel rhabdoviruses in the blood of healthy individuals from west Africa. PLoS Negl Trop Dis 9: e0003631.
-
134.
Kilianski A, Haas JL, Corriveau EJ, Liem AT, Willis KL, Kadavy DR, Rosenzweig CN, Minot SS, 2015. Bacterial and viral identification and differentiation by amplicon sequencing on the MinION nanopore sequencer. Gigascience 4: 12.
-
135.
Kilianski A, Roth PA, Liem AT, Hill JM, Willis KL, Rossmaier RD, Marinich AV, Maughan MN, Karavis MA, Kuhn JH, Honko AN, Rosenzweig CN, 2016. Use of unamplified RNA/cDNA-hybrid nanopore sequencing for rapid detection and characterization of RNA viruses. Emerg Infect Dis 22: 1448–1451.
-
136.
Benitez-Paez A, Portune K, Sanz Y, 2016. Species level resolution of 16S rRNA gene amplicons sequenced through MinION™ portable nanopore sequencer. GigaScience 5: 1–9.
-
137.
Backstedt BT, Buyuktanir O, Lindow J, Wunder EA Jr, Reis MG, Usmani-Brown S, Ledizet M, Ko A, Pal U, 2015. Efficient detection of pathogenic leptospires using 16S ribosomal RNA. PLoS One 10: e0128913.
-
138.
Tennant SM, Toema D, Qamar F, Iqbal N, Boyd MA, Marshall JM, Blackwelder WC, Wu Y, Quadri F, Khan A, Aziz F, Ahmad K, Kalam A, Asif E, Qureshi S, Khan E, Zaidi AK, Levine MM, 2015. Detection of typhoidal and paratyphoidal Salmonella in blood by real-time polymerase chain reaction. Clin Infect Dis 61 (Suppl 4): S241–S250.
-
139.
Head SR, Komori HK, LaMere SA, Whisenant T, Van Nieuwerburgh F, Salomon DR, Ordoukhanian P, 2014. Library construction for next-generation sequencing: overviews and challenges. Biotechniques 56: 61–64, 66, 68 passim.
-
140.
Mayxay M, Sengvilaipaseuth O, Chanthongthip A, Dubot-Peres A, Rolain JM, Parola P, Craig SB, Tulsiani S, Burns MA, Khanthavong M, Keola S, Pongvongsa T, Raoult D, Dittrich S, Newton PN, 2015. Causes of fever in rural southern Laos. Am J Trop Med Hyg 93: 517–520.
-
141.
Chandy S, Yoshimatsu K, Boorugu HK, Chrispal A, Thomas K, Peedicayil A, Abraham P, Arikawa J, Sridharan G, 2009. Acute febrile illness caused by hantavirus: serological and molecular evidence from India. Trans R Soc Trop Med Hyg 103: 407–412.
-
142.
Paris DH, Blacksell SD, Nawtaisong P, Jenjaroen K, Teeraratkul A, Chierakul W, Wuthiekanun V, Kantipong P, Day NP, 2011. Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute scrub typhus infection. PLoS Negl Trop Dis 5: e1307.
-
143.
Bingham AM, Cone M, Mock V, Heberlein-Larson L, Stanek D, Blackmore C, Likos A, 2016. Comparison of test results for Zika virus RNA in urine, serum, and saliva specimens from persons with travel-associated Zika virus disease—Florida, 2016. MMWR Morb Mortal Wkly Rep 65: 475–478.
-
144.
Zaas AK, Burke T, Chen M, McClain M, Nicholson B, Veldman T, Tsalik EL, Fowler V, Rivers EP, Otero R, Kingsmore SF, Voora D, Lucas J, Hero AO, Carin L, Woods CW, Ginsburg GS, 2013. A host-based RT-PCR gene expression signature to identify acute respiratory viral infection. Sci Transl Med 5: 203ra126.
-
145.
Kettler H, White K, Hawkes S, 2004. Mapping the landscape of diagnostics for sexually transmitted infections. Geneva, Switzerland: World Health Organization and TDR.
-
146.
Mabey D, Peeling RW, Ustianowski A, Perkins MD, 2004. Tropical infectious diseases: diagnostics for the developing world. Nat Rev Microbiol 2: 231–240.
-
147.
Peeling RW, Holmes KK, Mabey D, Ronald A, 2006. Rapid tests for sexually transmitted infections (STIs): the way forward. Sex Transm Infect 82: v1–v6.
-
148.
Ketema F, Zeh C, Edelman DC, Saville R, Constantine NT, 2001. Assessment of the performance of a rapid, lateral flow assay for the detection of antibodies to HIV. J Acquir Immune Defic Syndr 27: 63–70.
-
149.
Jarvis JN, Percival A, Bauman S, Pelfrey J, Meintjes G, Williams GN, Longley N, Harrison TS, Kozel TR, 2011. Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis. Clin Infect Dis 53: 1019–1023.
-
150.
Wilson ML, 2012. Malaria rapid diagnostic tests. Clin Infect Dis 54: 1637–1641.
-
151.
Yetisen AK, Akram MS, Lowe CR, 2013. Paper-based microfluidic point-of-care diagnostic devices. Lab Chip 13: 2210–2251.
-
152.
Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, Wong VL, Pohlmann RA, Ryan US, Whitesides GM, 2012. A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med 4: 152ra129.
-
153.
Gan W, Zhuang B, Zhang P, Han J, Li C-X, Liu P, 2014. A filter paper-based microdevice for low-cost, rapid, and automated DNA extraction and amplification from diverse sample types. Lab Chip 14: 3719–3728.
-
154.
Rodriguez NM, Linnes JC, Fan A, Ellenson CK, Pollock NR, Klapperich CM, 2015. Paper-based RNA extraction, in situ isothermal amplification, and lateral flow detection for low-cost, rapid diagnosis of Influenza A (H1N1) from clinical specimens. Anal Chem 87: 7872–7879.
-
155.
Connelly JT, Rolland JP, Whitesides GM, 2015. “Paper Machine” for molecular diagnostics. Anal Chem 87: 7595–7601.
-
156.
Houssin T, Cramer J, Grojsman R, Bellahsene L, Colas G, Moulet H, Minnella W, Pannetier C, Leberre M, Plecis A, Chen Y, 2016. Ultrafast, sensitive and large-volume on-chip real-time PCR for the molecular diagnosis of bacterial and viral infections. Lab Chip 16: 1401–1411.
-
157.
Son JH, Cho B, Hong S, Lee SH, Hoxha O, Haack AJ, Lee LP, 2015. Ultrafast photonic PCR. Light Sci Appl 4: e280.
-
158.
Wilson NO, Adjei AA, Anderson W, Baidoo S, Stiles JK, 2008. Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients. Am J Trop Med Hyg 78: 733–735.
-
159.
Korhonen EM, Huhtamo E, Virtala AM, Kantele A, Vapalahti O, 2014. Approach to non-invasive sampling in dengue diagnostics: exploring virus and NS1 antigen detection in saliva and urine of travelers with dengue. J Clin Virol 61: 353–358.
-
160.
Nie S, Benito-Pena E, Zhang H, Wu Y, Walt DR, 2013. Multiplexed salivary protein profiling for patients with respiratory diseases using fiber-optic bundles and fluorescent antibody-based microarrays. Anal Chem 85: 9272–9280.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1832 | 1377 | 65 |
| Full Text Views | 672 | 21 | 0 |
| PDF Downloads | 316 | 20 | 0 |
Reducing Uncertainty for Acute Febrile Illness in Resource-Limited Settings: The Current Diagnostic Landscape
Matthew L. Robinson
Matthew L. Robinson
Division of Infectious Disease, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Search for other papers by Matthew L. Robinson in
Current site
Google Scholar
PubMed
Search for other papers by Matthew L. Robinson in
Current site
Google Scholar
PubMed
Yukari C. Manabe
Yukari C. Manabe
Division of Infectious Disease, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Search for other papers by Yukari C. Manabe in
Current site
Google Scholar
PubMed
Search for other papers by Yukari C. Manabe in
Current site
Google Scholar
PubMed
Diagnosing the cause of acute febrile illness in resource-limited settings is important—to give the correct antimicrobials to patients who need them, to prevent unnecessary antimicrobial use, to detect emerging infectious diseases early, and to guide vaccine deployment. A variety of approaches are yielding more rapid and accurate tests that can detect more pathogens in a wider variety of settings. After decades of slow progress in diagnostics for acute febrile illness in resource-limited settings, a wave of converging advancements will enable clinicians in resource-limited settings to reduce uncertainty for the diagnosis of acute febrile illness.
Author Notes
Authors' addresses: Matthew L. Robinson, Division of Infectious Disease, Johns Hopkins School of Medicine, Baltimore, MD, E-mail: mrobin85@jhmi.edu. Yukari C. Manabe, Department of Medicine, Johns Hopkins University, Baltimore, MD, E-mail: ymanabe@jhmi.edu.
- Finding the Correct Diagnosis for Acute Febrile Illness Matters
- Traditional Microbiology Techniques Reinvent Themselves
- Nucleic Acid Amplification Tests are Becoming Easier to Use
- Metagenomic Sequencing Can Identify Any Pathogen
- New Molecular Techniques are Not Perfect
- Put It On Paper, or On a Chip, and Throw Away the Needle
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Van Hemelrijck MJ, Lindblade KA, Kubaje A, Hamel MJ, Odhiambo F, Phillips-Howard PA, Laserson KF, Slutsker L, Feikin DR, 2009. Trends observed during a decade of paediatric sick visits to peripheral health facilities in rural western Kenya, 1997–2006. Trop Med Int Health 14: 62–69.
-
2.
Salvi S, Apte K, Madas S, Barne M, Chhowala S, Sethi T, Aggarwal K, Agrawal A, Gogtay J, 2015. Symptoms and medical conditions in 204 912 patients visiting primary health-care practitioners in India: a 1-day point prevalence study (the POSEIDON study). Lancet Glob Health 3: e776–e784.
-
3.
Crump JA, Kirk MD, 2015. Estimating the burden of febrile illnesses. PLoS Negl Trop Dis 9: e0004040.
-
4.
GBD 2013 DALYs and HALE Collaborators, Murray CJ, Barber RM, Foreman KJ, Abbasoglu Ozgoren A, Abd-Allah F, Abera SF, Aboyans V, Abraham JP, Abubakar I, Abu-Raddad LJ, Abu-Rmeileh NM, Achoki T, Ackerman IN, Ademi Z, Adou AK, Adsuar JC, Afshin A, Agardh EE, Alam SS, Alasfoor D, Albittar MI, Alegretti MA, Alemu ZA, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allebeck P, Almazroa MA, Alsharif U, Alvarez E, Alvis-Guzman N, Amare AT, Ameh EA, Amini H, Ammar W, Anderson HR, Anderson BO, Antonio CA, Anwari P, Arnlov J, Arsic Arsenijevic VS, Artaman A, Asghar RJ, Assadi R, Atkins LS, Avila MA, Awuah B, Bachman VF, Badawi A, Bahit MC, Balakrishnan K, Banerjee A, Barker-Collo SL, Barquera S, Barregard L, Barrero LH, Basu A, Basu S, Basulaiman MO, Beardsley J, Bedi N, Beghi E, Bekele T, Bell ML, Benjet C, Bennett DA, Bensenor IM, Benzian H, Bernabe E, Bertozzi-Villa A, Beyene TJ, Bhala N, Bhalla A, Bhutta ZA, Bienhoff K, Bikbov B, Biryukov S, Blore JD, Blosser CD, Blyth FM, Bohensky MA, Bolliger IW, Bora Basara B, Bornstein NM, Bose D, Boufous S, Bourne RR, Boyers LN, Brainin M, Brayne CE, Brazinova A, Breitborde NJ, Brenner H, Briggs AD, Brooks PM, Brown JC, Brugha TS, Buchbinder R, Buckle GC, Budke CM, Bulchis A, Bulloch AG, Campos-Nonato IR, Carabin H, Carapetis JR, Cárdenas R, Carpenter DO, Caso V, Castañeda-Orjuela CA, Castro RE, Catalá-López F, Cavalleri F, Çavlin A, Chadha VK, Chang JC, Charlson FJ, Chen H, Chen W, Chiang PP, Chimed-Ochir O, Chowdhury R, Christensen H, Christophi CA, Cirillo M, Coates MM, Coffeng LE, Coggeshall MS, Colistro V, Colquhoun SM, Cooke GS, Cooper C, Cooper LT, Coppola LM, Cortinovis M, Criqui MH, Crump JA, Cuevas-Nasu L, Danawi H, Dandona L, Dandona R, Dansereau E, Dargan PI, Davey G, Davis A, Davitoiu DV, Dayama A, De Leo D, Degenhardt L, Del Pozo-Cruz B, Dellavalle RP, Deribe K, Derrett S, Des Jarlais DC, Dessalegn M, Dharmaratne SD, Dherani MK, Diaz-Torné C, Dicker D, Ding EL, Dokova K, Dorsey ER, Driscoll TR, Duan L, Duber HC, Ebel BE, Edmond KM, Elshrek YM, Endres M, Ermakov SP, Erskine HE, Eshrati B, Esteghamati A, Estep K, Faraon EJ, Farzadfar F, Fay DF, Feigin VL, Felson DT, Fereshtehnejad SM, Fernandes JG, Ferrari AJ, Fitzmaurice C, Flaxman AD, Fleming TD, Foigt N, Forouzanfar MH, Fowkes FG, Paleo UF, Franklin RC, Fürst T, Gabbe B, Gaffikin L, Gankpé FG, Geleijnse JM, Gessner BD, Gething P, Gibney KB, Giroud M, Giussani G, Gomez Dantes H, Gona P, González-Medina D, Gosselin RA, Gotay CC, Goto A, Gouda HN, Graetz N, Gugnani HC, Gupta R, Gupta R, Gutiérrez RA, Haagsma J, Hafezi-Nejad N, Hagan H, Halasa YA, Hamadeh RR, Hamavid H, Hammami M, Hancock J, Hankey GJ, Hansen GM, Hao Y, Harb HL, Haro JM, Havmoeller R, Hay SI, Hay RJ, Heredia-Pi IB, Heuton KR, Heydarpour P, Higashi H, Hijar M, Hoek HW, Hoffman HJ, Hosgood HD, Hossain M, Hotez PJ, Hoy DG, Hsairi M, Hu G, Huang C, Huang JJ, Husseini A, Huynh C, Iannarone ML, Iburg KM, Innos K, Inoue M, Islami F, Jacobsen KH, Jarvis DL, Jassal SK, Jee SH, Jeemon P, Jensen PN, Jha V, Jiang G, Jiang Y, Jonas JB, Juel K, Kan H, Karch A, Karema CK, Karimkhani C, Karthikeyan G, Kassebaum NJ, Kaul A, Kawakami N, Kazanjan K, Kemp AH, Kengne AP, Keren A, Khader YS, Khalifa SE, Khan EA, Khan G, Khang YH, Kieling C, Kim D, Kim S, Kim Y, Kinfu Y, Kinge JM, Kivipelto M, Knibbs LD, Knudsen AK, Kokubo Y, Kosen S, Krishnaswami S, Kuate Defo B, Kucuk Bicer B, Kuipers EJ, Kulkarni C, Kulkarni VS, Kumar GA, Kyu HH, Lai T, Lalloo R, Lallukka T, Lam H, Lan Q, Lansingh VC, Larsson A, Lawrynowicz AE, Leasher JL, Leigh J, Leung R, Levitz CE, Li B, Li Y, Li Y, Lim SS, Lind M, Lipshultz SE, Liu S, Liu Y, Lloyd BK, Lofgren KT, Logroscino G, Looker KJ, Lortet-Tieulent J, Lotufo PA, Lozano R, Lucas RM, Lunevicius R, Lyons RA, Ma S, Macintyre MF, Mackay MT, Majdan M, Malekzadeh R, Marcenes W, Margolis DJ, Margono C, Marzan MB, Masci JR, Mashal MT, Matzopoulos R, Mayosi BM, Mazorodze TT, Mcgill NW, Mcgrath JJ, Mckee M, Mclain A, Meaney PA, Medina C, Mehndiratta MM, Mekonnen W, Melaku YA, Meltzer M, Memish ZA, Mensah GA, Meretoja A, Mhimbira FA, Micha R, Miller TR, Mills EJ, Mitchell PB, Mock CN, Mohamed Ibrahim N, Mohammad KA, Mokdad AH, Mola GL, Monasta L, Montañez Hernandez JC, Montico M, Montine TJ, Mooney MD, Moore AR, Moradi-Lakeh M, Moran AE, Mori R, Moschandreas J, Moturi WN, Moyer ML, Mozaffarian D, Msemburi WT, Mueller UO, Mukaigawara M, Mullany EC, Murdoch ME, Murray J, Murthy KS, Naghavi M, Naheed A, Naidoo KS, Naldi L, Nand D, Nangia V, Narayan KM, Nejjari C, Neupane SP, Newton CR, Ng M, Ngalesoni FN, Nguyen G, Nisar MI, Nolte S, Norheim OF, Norman RE, Norrving B, Nyakarahuka L, Oh IH, Ohkubo T, Ohno SL, Olusanya BO, Opio JN, Ortblad K, Ortiz A, Pain AW, Pandian JD, Panelo CI, Papachristou C, Park EK, Park JH, Patten SB, Patton GC, Paul VK, Pavlin BI, Pearce N, Pereira DM, Perez-Padilla R, Perez-Ruiz F, Perico N, Pervaiz A, Pesudovs K, Peterson CB, Petzold M, Phillips MR, Phillips BK, Phillips DE, Piel FB, Plass D, Poenaru D, Polinder S, Pope D, Popova S, Poulton RG, Pourmalek F, Prabhakaran D, Prasad NM, Pullan RL, Qato DM, Quistberg DA, Rafay A, Rahimi K, Rahman SU, Raju M, Rana SM, Razavi H, Reddy KS, Refaat A, Remuzzi G, Resnikoff S, Ribeiro AL, Richardson L, Richardus JH, Roberts DA, Rojas-Rueda D, Ronfani L, Roth GA, Rothenbacher D, Rothstein DH, Rowley JT, Roy N, Ruhago GM, Saeedi MY, Saha S, Sahraian MA, Sampson UK, Sanabria JR, Sandar L, Santos IS, Satpathy M, Sawhney M, Scarborough P, Schneider IJ, Schöttker B, Schumacher AE, Schwebel DC, Scott JG, Seedat S, Sepanlou SG, Serina PT, Servan-Mori EE, Shackelford KA, Shaheen A, Shahraz S, Shamah Levy T, Shangguan S, She J, Sheikhbahaei S, Shi P, Shibuya K, Shinohara Y, Shiri R, Shishani K, Shiue I, Shrime MG, Sigfusdottir ID, Silberberg DH, Simard EP, Sindi S, Singh A, Singh JA, Singh L, Skirbekk V, Slepak EL, Sliwa K, Soneji S, Søreide K, Soshnikov S, Sposato LA, Sreeramareddy CT, Stanaway JD, Stathopoulou V, Stein DJ, Stein MB, Steiner C, Steiner TJ, Stevens A, Stewart A, Stovner LJ, Stroumpoulis K, Sunguya BF, Swaminathan S, Swaroop M, Sykes BL, Tabb KM, Takahashi K, Tandon N, Tanne D, Tanner M, Tavakkoli M, Taylor HR, Te Ao BJ, Tediosi F, Temesgen AM, Templin T, Ten Have M, Tenkorang EY, Terkawi AS, Thomson B, Thorne-Lyman AL, Thrift AG, Thurston GD, Tillmann T, Tonelli M, Topouzis F, Toyoshima H, Traebert J, Tran BX, Trillini M, Truelsen T, Tsilimbaris M, Tuzcu EM, Uchendu US, Ukwaja KN, Undurraga EA, Uzun SB, Van Brakel WH, Van De Vijver S, van Gool CH, Van Os J, Vasankari TJ, Venketasubramanian N, Violante FS, Vlassov VV, Vollset SE, Wagner GR, Wagner J, Waller SG, Wan X, Wang H, Wang J, Wang L, Warouw TS, Weichenthal S, Weiderpass E, Weintraub RG, Wenzhi W, Werdecker A, Westerman R, Whiteford HA, Wilkinson JD, Williams TN, Wolfe CD, Wolock TM, Woolf AD, Wulf S, Wurtz B, Xu G, Yan LL, Yano Y, Ye P, Yentür GK, Yip P, Yonemoto N, Yoon SJ, Younis MZ, Yu C, Zaki ME, Zhao Y, Zheng Y, Zonies D, Zou X, Salomon JA, Lopez AD, Vos T, 2015. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition. Lancet 386: 2145–2191.
-
5.
Institute for Health Metrics and Evaluation (IHME), 2015. GBD Compare. Available at: http://vizhub.healthdata.org/gbd-compare. Accessed August 1, 2016.
-
6.
Punjabi NH, Taylor WR, Murphy GS, Purwaningsih S, Picarima H, Sisson J, Olson JG, Baso S, Wangsasaputra F, Lesmana M, Oyofo BA, Simanjuntak CH, Subekti D, Corwin AL, Richie TL, 2012. Etiology of acute, non-malaria, febrile illnesses in Jayapura, northeastern Papua, Indonesia. Am J Trop Med Hyg 86: 46–51.
-
7.
Crump JA, Morrissey AB, Nicholson WL, Massung RF, Stoddard RA, Galloway RL, Ooi EE, Maro VP, Saganda W, Kinabo GD, Muiruri C, Bartlett JA, 2013. Etiology of severe non-malaria febrile illness in northern Tanzania: a prospective cohort study. PLoS Negl Trop Dis 7: e2324.
-
8.
D'Acremont V, Kilowoko M, Kyungu E, Philipina S, Sangu W, Kahama-Maro J, Lengeler C, Cherpillod P, Kaiser L, Genton B, 2014. Beyond malaria–causes of fever in outpatient Tanzanian children. N Engl J Med 370: 809–817.
-
9.
Mayxay M, Castonguay-Vanier J, Chansamouth V, Dubot-Peres A, Paris DH, Phetsouvanh R, Tangkhabuanbutra J, Douangdala P, Inthalath S, Souvannasing P, Slesak G, Tongyoo N, Chanthongthip A, Panyanouvong P, Sibounheuang B, Phommasone K, Dohnt M, Phonekeo D, Hongvanthong B, Xayadeth S, Ketmayoon P, Blacksell SD, Moore CE, Craig SB, Burns MA, von Sonnenburg F, Corwin A, de Lamballerie X, Gonzalez IJ, Christophel EM, Cawthorne A, Bell D, Newton PN, 2013. Causes of non-malarial fever in Laos: a prospective study. Lancet Glob Health 1: e46–e54.
-
10.
Chheng K, Carter MJ, Emary K, Chanpheaktra N, Moore CE, Stoesser N, Putchhat H, Sona S, Reaksmey S, Kitsutani P, Sar B, van Doorn HR, Uyen NH, Van Tan L, Paris D, Blacksell SD, Amornchai P, Wuthiekanun V, Parry CM, Day NPJ, Kumar V, 2013. A prospective study of the causes of febrile illness requiring hospitalization in children in Cambodia. PLoS One 8: e60634.
-
11.
Mueller TC, Siv S, Khim N, Kim S, Fleischmann E, Ariey F, Buchy P, Guillard B, González IJ, Christophel E-M, Abdur R, von Sonnenburg F, Bell D, Menard D, 2014. Acute undifferentiated febrile illness in rural Cambodia: a 3-year prospective observational study. PLoS One 9: e95868.
-
12.
Manock SR, Jacobsen KH, de Bravo NB, Russell KL, Negrete M, Olson JG, Sanchez JL, Blair PJ, Smalligan RD, Quist BK, Espin JF, Espinoza WR, MacCormick F, Fleming LC, Kochel T, 2009. Etiology of acute undifferentiated febrile illness in the Amazon basin of Ecuador. Am J Trop Med Hyg 81: 146–151.
-
13.
Kasper MR, Blair PJ, Touch S, Sokhal B, Yasuda CY, Williams M, Richards AL, Burgess TH, Wierzba TF, Putnam SD, 2012. Infectious etiologies of acute febrile illness among patients seeking health care in south-central Cambodia. Am J Trop Med Hyg 86: 246–253.
-
14.
Rubach MP, Maro VP, Bartlett JA, Crump JA, 2015. Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy. Am J Trop Med Hyg 92: 454–462.
-
15.
Bassat Q, Machevo S, O'Callaghan-Gordo C, Sigauque B, Morais L, Diez-Padrisa N, Ribo JL, Mandomando I, Nhampossa T, Ayala E, Sanz S, Weber M, Roca A, Alonso PL, 2011. Distinguishing malaria from severe pneumonia among hospitalized children who fulfilled integrated management of childhood illness criteria for both diseases: a hospital-based study in Mozambique. Am J Trop Med Hyg 85: 626–634.
-
16.
Laxminarayan R, Matsoso P, Pant S, Brower C, Rottingen JA, Klugman K, Davies S, 2016. Access to effective antimicrobials: a worldwide challenge. Lancet 387: 168–175.
-
17.
Holman RC, Paddock CD, Curns AT, Krebs JW, McQuiston JH, Childs JE, 2001. Analysis of risk factors for fatal Rocky Mountain Spotted Fever: evidence for superiority of tetracyclines for therapy. J Infect Dis 184: 1437–1444.
-
18.
Yasunaga H, Horiguchi H, Kuwabara K, Hashimoto H, Matsuda S, 2011. Delay in tetracycline treatment increases the risk of complications in Tsutsugamushi disease: data from the Japanese Diagnosis Procedure Combination database. Intern Med 50: 37–42.
-
19.
Prabhu M, Nicholson WL, Roche AJ, Kersh GJ, Fitzpatrick KA, Oliver LD, Massung RF, Morrissey AB, Bartlett JA, Onyango JJ, Maro VP, Kinabo GD, Saganda W, Crump JA, 2011. Q fever, spotted fever group, and typhus group rickettsioses among hospitalized febrile patients in northern Tanzania. Clin Infect Dis 53: e8–e15.
-
20.
Dittrich S, Rattanavong S, Lee SJ, Panyanivong P, Craig SB, Tulsiani SM, Blacksell SD, Dance DAB, Dubot-Pérès A, Sengduangphachanh A, Phoumin P, Paris DH, Newton PN, 2015. Orientia, Rickettsia, and leptospira pathogens as causes of CNS infections in Laos: a prospective study. Lancet Glob Health 3: e104–e112.
-
21.
Jacob ST, Pavlinac PB, Nakiyingi L, Banura P, Baeten JM, Morgan K, Magaret A, Manabe Y, Reynolds SJ, Liles WC, Wald A, Joloba ML, Mayanja-Kizza H, Scheld WM, 2013. Mycobacterium tuberculosis bacteremia in a cohort of HIV-infected patients hospitalized with severe sepsis in Uganda–high frequency, low clinical sand derivation of a clinical prediction score. PLoS One 8: e70305.
-
22.
Chandy SJ, Thomas K, Mathai E, Antonisamy B, Holloway KA, Stalsby Lundborg C, 2013. Patterns of antibiotic use in the community and challenges of antibiotic surveillance in a lower-middle-income country setting: a repeated cross-sectional study in Vellore, south India. J Antimicrob Chemother 68: 229–236.
-
23.
Elfving K, Shakely D, Andersson M, Baltzell K, Ali AS, Bachelard M, Falk KI, Ljung A, Msellem MI, Omar RS, Parola P, Xu W, Petzold M, Trollfors B, Björkman A, Lindh M, Mårtensson A, 2016. Acute uncomplicated febrile illness in children aged 2–59 months in Zanzibar—aetiologies, antibiotic treatment and outcome. PLoS One 11: e0146054.
-
24.
Juma E, Zurovac D, 2011. Changes in health workers' malaria diagnosis and treatment practices in Kenya. Malar J 10: 1.
-
25.
Batwala V, Magnussen P, Nuwaha F, 2011. Antibiotic use among patients with febrile illness in a low malaria endemicity setting in Uganda. Malar J 10: 377.
-
26.
Holloway KA, Rosella L, Henry D, 2016. The impact of WHO essential medicines policies on inappropriate use of antibiotics. PLoS One 11: e0152020.
-
27.
Brink AJ, Messina AP, Feldman C, Richards GA, Becker PJ, Goff DA, Bauer KA, Nathwani D, van den Bergh D; Netcare Antimicrobial Stewardship Study Alliance, 2016. Antimicrobial stewardship across 47 South African hospitals: an implementation study. Lancet Infect Dis 16: 1017–1025.
-
28.
Čižman M, 2003. The use and resistance to antibiotics in the community. Int J Antimicrob Agents 21: 297–307.
-
29.
Chatterjee D, Sen S, Begum SA, Adhikari A, Hazra A, Das AK, 2015. A questionnaire-based survey to ascertain the views of clinicians regarding rational use of antibiotics in teaching hospitals of Kolkata. Indian J Pharmacol 47: 105–108.
-
30.
D'Acremont V, Kahama-Maro J, Swai N, Mtasiwa D, Genton B, Lengeler C, 2011. Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled study. Malar J 10: 107.
-
31.
Ndhlovu M, Nkhama E, Miller JM, Hamer DH, 2015. Antibiotic prescribing practices for patients with fever in the transition from presumptive treatment of malaria to ‘confirm and treat’ in Zambia: a cross-sectional study. Trop Med Int Health 20: 1696–1706.
-
32.
Ssekabira U, Bukirwa H, Hopkins H, Namagembe A, Weaver MR, Sebuyira LM, Quick L, Staedke S, Yeka A, Kiggundu M, Schneider G, McAdam K, Wabwire-Mangen F, Dorsey G, 2008. Improved malaria case management after integrated team-based training of health care workers in Uganda. Am J Trop Med Hyg 79: 826–833.
-
33.
Moon AM, Biggs HM, Rubach MP, Crump JA, Maro VP, Saganda W, Reddy EA, 2014. Evaluation of in-hospital management for febrile illness in northern Tanzania before and after 2010 World Health Organization Guidelines for the treatment of malaria. PLoS One 9: e89814.
-
34.
Joshi R, Colford JM Jr, Reingold AL, Kalantri S, 2008. Nonmalarial acute undifferentiated fever in a rural hospital in central India: diagnostic uncertainty and overtreatment with antimalarial agents. Am J Trop Med Hyg 78: 393–399.
-
35.
Reyburn H, Mbakilwa H, Mwangi R, Mwerinde O, Olomi R, Drakeley C, Whitty CJM, 2007. Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial. BMJ 334: 403.
-
36.
Hamer DH, Ndhlovu M, Zurovac D, Fox M, Yeboah-Antwi K, Chanda P, Sipilinyambe N, Simon JL, Snow RW, 2007. Improved diagnostic testing and malaria treatment practices in Zambia. JAMA 297: 2227–2231.
-
37.
Sudhinaraset M, Ingram M, Lofthouse HK, Montagu D, 2013. What is the role of informal healthcare providers in developing countries? A systematic review. PLoS One 8: e54978.
-
38.
Ocan M, Manabe YC, Baluku H, Atukwase E, Ogwal-Okeng J, Obua C, 2015. Prevalence and predictors of prior antibacterial use among patients presenting to hospitals in northern Uganda. BMC Pharmacol Toxicol 16: 26.
-
39.
Alsan M, Schoemaker L, Eggleston K, Kammili N, Kolli P, Bhattacharya J, 2015. Out-of-pocket health expenditures and antimicrobial resistance in low-income and middle-income countries: an economic analysis. Lancet Infect Dis 15: 1203–1210.
-
40.
Goossens H, Ferech M, Stichele RV, Elseviers M, ESAC Project Group, 2005. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 365: 579–587.
-
41.
Holmes AH, Moore LS, Sundsfjord A, Steinbakk M, Regmi S, Karkey A, Guerin PJ, Piddock LJ, 2016. Understanding the mechanisms and drivers of antimicrobial resistance. Lancet 387: 176–187.
-
42.
Van Boeckel TP, Gandra S, Ashok A, Caudron Q, Grenfell BT, Levin SA, Laxminarayan R, 2014. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis 14: 742–750.
-
43.
Castanheira M, Farrell SE, Krause KM, Jones RN, Sader HS, 2014. Contemporary diversity of beta-lactamases among Enterobacteriaceae in the nine U.S. census regions and ceftazidime-avibactam activity tested against isolates producing the most prevalent beta-lactamase groups. Antimicrob Agents Chemother 58: 833–838.
-
44.
Morens DM, Fauci AS, 2013. Emerging infectious diseases: threats to human health and global stability. PLoS Pathog 9: e1003467.
-
45.
Faria NR, Azevedo RSS, Kraemer MUG, Souza R, Cunha MS, Hill SC, Thézé J, Bonsall MB, Bowden TA, Rissanen I, Rocco IM, Nogueira JS, Maeda AY, Vasami FG, Macedo FL, Suzuki A, Rodrigues SG, Cruz ACR, Nunes BT, Medeiros DB, Rodrigues DSG, Nunes Queiroz AL, da Silva EVP, Henriques DF, Travassos da Rosa ES, de Oliveira CS, Martins LC, Vasconcelos HB, Casseb LMN, Simith D de B, Messina JP, Abade L, Lourenço J, Alcantara LCJ, de Lima MM, Giovanetti M, Hay SI, de Oliveira RS, Lemos P da S, Oliveira LF, de Lima CPS, da Silva SP, Vasconcelos JM, Franco L, Cardoso JF, Vianez-Júnior JL, Mir D, Bello G, Delatorre E, Khan K, Creatore M, Coelho GE, de Oliveira WK, Tesh R, Pybus OG, Nunes MRT, Vasconcelos PFC, 2016. Zika virus in the Americas: early epidemiological and genetic findings. Science 352: 345–349.
-
46.
Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N, Soropogui B, Sow MS, Keita S, De Clerck H, Tiffany A, Dominguez G, Loua M, Traore A, Kolie M, Malano ER, Heleze E, Bocquin A, Mely S, Raoul H, Caro V, Cadar D, Gabriel M, Pahlmann M, Tappe D, Schmidt-Chanasit J, Impouma B, Diallo AK, Formenty P, Van Herp M, Gunther S, 2014. Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med 371: 1418–1425.
-
47.
Dixon MG, Schafer IJ; Centers for Disease Control Prevention, 2014. Ebola viral disease outbreak–west Africa, 2014. MMWR Morb Mortal Wkly Rep 63: 548–551.
-
48.
Dhillon RS, Srikrishna D, Garry RF, Chowell G, 2015. Ebola control: rapid diagnostic testing. Lancet Infect Dis 15: 147–148.
-
49.
Lewnard JA, Ndeffo Mbah ML, Alfaro-Murillo JA, Altice FL, Bawo L, Nyenswah TG, Galvani AP, 2014. Dynamics and control of Ebola virus transmission in Montserrado, Liberia: a mathematical modelling analysis. Lancet Infect Dis 14: 1189–1195.
-
50.
Henao-Restrepo AM, Longini IM, Egger M, Dean NE, Edmunds WJ, Camacho A, Carroll MW, Doumbia M, Draguez B, Duraffour S, Enwere G, Grais R, Gunther S, Hossmann S, Konde MK, Kone S, Kuisma E, Levine MM, Mandal S, Norheim G, Riveros X, Soumah A, Trelle S, Vicari AS, Watson CH, Keita S, Kieny MP, Rottingen JA, 2015. Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. Lancet 386: 857–866.
-
51.
Slater HC, Ross A, Ouedraogo AL, White LJ, Nguon C, Walker PGT, Ngor P, Aguas R, Silal SP, Dondorp AM, La Barre P, Burton R, Sauerwein RW, Drakeley C, Smith TA, Bousema T, Ghani AC, 2015. Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies. Nature 528: S94–S101.
-
52.
Andrews JR, Prajapati KG, Eypper E, Shrestha P, Shakya M, Pathak KR, Joshi N, Tiwari P, Risal M, Koirala S, Karkey A, Dongol S, Wen S, Smith AB, Maru D, Basnyat B, Baker S, Farrar J, Ryan ET, Hohmann E, Arjyal A, 2013. Evaluation of an electricity-free, culture-based approach for detecting typhoidal Salmonella bacteremia during enteric fever in a high burden, resource-limited setting. PLoS Negl Trop Dis 7: e2292.
-
53.
D'Ambrosio MV, Bakalar M, Bennuru S, Reber C, Skandarajah A, Nilsson L, Switz N, Kamgno J, Pion S, Boussinesq M, Nutman TB, Fletcher DA, 2015. Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope. Sci Transl Med 7: 286re4.
-
54.
Pirnstill CW, Coté GL, 2015. Malaria diagnosis using a mobile phone polarized microscope. Sci Rep 5: 13368.
-
55.
Lukianova-Hleb EY, Campbell KM, Constantinou PE, Braam J, Olson JS, Ware RE, Sullivan DJ Jr, Lapotko DO, 2014. Hemozoin-generated vapor nanobubbles for transdermal reagent- and needle-free detection of malaria. Proc Natl Acad Sci USA 111: 900–905.
-
56.
Ekaterina L-H, Sarah B, Reka S, Alexander K, Thomas K, Andrew H, Michail B, Nirbhay K, Umberto DA, Dmitri L, 2015. Transdermal diagnosis of malaria using vapor nanobubbles. Emerg Infect Dis 21: 1122.
-
57.
Bisser S, Lumbala C, Nguertoum E, Kande V, Flevaud L, Vatunga G, Boelaert M, Büscher P, Josenando T, Bessell PR, Biéler S, Ndung'u JM, 2016. Sensitivity and specificity of a prototype rapid diagnostic test for the detection of Trypanosoma brucei gambiense infection: a multi-centric prospective study. PLoS Negl Trop Dis 10: e0004608.
-
58.
Xu GJ, Kula T, Xu Q, Li MZ, Vernon SD, Ndung'u T, Ruxrungtham K, Sanchez J, Brander C, Chung RT, O'Connor KC, Walker B, Larman HB, Elledge SJ, 2015. Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome. Science 348 (6239): aaa0698.
-
59.
Jung JH, Lee JE, 2016. Real-time bacterial microcolony counting using on-chip microscopy. Sci Rep 6: 21473.
-
60.
Leung K, Zahn H, Leaver T, Konwar KM, Hanson NW, Pagé AP, Lo C-C, Chain PS, Hallam SJ, Hansen CL, 2012. A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities. Proc Natl Acad Sci USA 109: 7665–7670.
-
61.
Shemesh J, Ben Arye T, Avesar J, Kang JH, Fine A, Super M, Meller A, Ingber DE, Levenberg S, 2014. Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis. Proc Natl Acad Sci USA 111: 11293–11298.
-
62.
Choi J, Yoo J, Lee M, Kim EG, Lee JS, Lee S, Joo S, Song SH, Kim EC, Lee JC, Kim HC, Jung YG, Kwon S, 2014. A rapid antimicrobial susceptibility test based on single-cell morphological analysis. Sci Transl Med 6: 267ra174.
-
63.
Lee J, Armstrong DT, Ssengooba W, Park J-a, Yu Y, Mumbowa F, Namaganda C, Mboowa G, Nakayita G, Armakovitch S, Chien G, Cho S-N, Via LE, Barry CE, Ellner JJ, Alland D, Dorman SE, Joloba ML, 2014. Sensititre MYCOTB MIC plate for testing Mycobacterium tuberculosis susceptibility to first- and second-line drugs. Antimicrob Agents Chemother 58: 11–18.
-
64.
Laksanasopin T, Guo TW, Nayak S, Sridhara AA, Xie S, Olowookere OO, Cadinu P, Meng F, Chee NH, Kim J, Chin CD, Munyazesa E, Mugwaneza P, Rai AJ, Mugisha V, Castro AR, Steinmiller D, Linder V, Justman JE, Nsanzimana S, Sia SK, 2015. A smartphone dongle for diagnosis of infectious diseases at the point of care. Sci Transl Med 7: 273re1.
-
65.
Park TS, Li W, McCracken KE, Yoon J-Y, 2013. Smartphone quantifies Salmonella from paper microfluidics. Lab Chip 13: 4832–4840.
-
66.
Bristow CC, Leon SR, Ramos LB, Vargas SK, Flores JA, Konda KA, Caceres CF, Klausner JD, 2015. Laboratory evaluation of a dual rapid immunodiagnostic test for HIV and syphilis infection. J Clin Microbiol 53: 311–313.
-
67.
Herbst de Cortina S, Bristow CC, Vargas SK, Perez DG, Konda KA, Caceres CF, Klausner JD, 2016. Laboratory evaluation of a point-of-care downward-flow assay for simultaneous detection of antibodies to Treponema pallidum and human immunodeficiency virus. J Clin Microbiol 54: 1922–1924.
-
68.
Leon SR, Ramos LB, Vargas SK, Kojima N, Perez DG, Caceres CF, Klausner JD, 2016. Laboratory evaluation of a dual-path platform assay for rapid point-of-care HIV and syphilis testing. J Clin Microbiol 54: 492–494.
-
69.
Deraney RN, Mace CR, Rolland JP, Schonhorn JE, 2016. Multiplexed, patterned-paper immunoassay for detection of malaria and dengue fever. Anal Chem 88: 6161–6165.
-
70.
Gao C-h, Yang Y-t, Shi F, Wang J-y, Steverding D, Wang X, 2015. Development of an immunochromatographic test for diagnosis of visceral leishmaniasis based on detection of a circulating antigen. PLoS Negl Trop Dis 9: e0003902.
-
71.
FIND, 2016. Negotiated Product Pricing. Available at: http://www.finddx.org/find-negotiated-product-pricing/. Accessed December 16, 2016.
-
72.
World Health Organization, 2011. Visceral Leishmaniasis Rapid Diagnostic Test Performance. Available at: http://www.who.int/tdr/publications/documents/vl-rdt-evaluation.pdf. Accessed December 19, 2016.
-
73.
Baron EJ, Miller JM, Weinstein MP, Richter SS, Gilligan PH, Thomson RB Jr, Bourbeau P, Carroll KC, Kehl SC, Dunne WM, Robinson-Dunn B, Schwartzman JD, Chapin KC, Snyder JW, Forbes BA, Patel R, Rosenblatt JE, Pritt BS, 2013. A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM). Clin Infect Dis 57: e22–e121.
-
74.
Piepenburg O, Williams CH, Stemple DL, Armes NA, 2006. DNA detection using recombination proteins. PLoS Biol 4: e204.
-
75.
Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, Hase T, 2000. Loop-mediated isothermal amplification of DNA. Nucleic Acids Res 28: e63.
-
76.
Guatelli JC, Whitfield KM, Kwoh DY, Barringer KJ, Richman DD, Gingeras TR, 1990. Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication. Proc Natl Acad Sci USA 87: 1874–1878.
-
77.
Crannell ZA, Rohrman B, Richards-Kortum R, 2014. Equipment-free incubation of recombinase polymerase amplification reactions using body heat. PLoS One 9: e112146.
-
78.
Nie S, Roth RB, Stiles J, Mikhlina A, Lu X, Tang YW, Babady NE, 2014. Evaluation of Alere i Influenza A and B for rapid detection of influenza viruses A and B. J Clin Microbiol 52: 3339–3344.
-
79.
Fisher Scientific, Alere i Influenza A and B. Available at: https://www.fishersci.com/shop/products/alere-i-influenza-a-b-3/p-4898455. Accessed July 19, 2016.
-
80.
Buss SN, Leber A, Chapin K, Fey PD, Bankowski MJ, Jones MK, Rogatcheva M, Kanack KJ, Bourzac KM, 2015. Multicenter evaluation of the BioFire FilmArray gastrointestinal panel for etiologic diagnosis of infectious gastroenteritis. J Clin Microbiol 53: 915–925.
-
81.
Leber AL, Everhart K, Balada-Llasat JM, Cullison J, Daly J, Holt S, Lephart P, Salimnia H, Schreckenberger PC, DesJarlais S, Reed SL, Chapin KC, LeBlanc L, Johnson JK, Soliven NL, Carroll K, Miller JA, Dien Bard J, Mestas J, Bankowski M, Enomoto T, Hemmert AC, Bourzac K, 2016. Multicenter evaluation of the BioFire FilmArray meningitis encephalitis panel for the detection of bacteria, ciruses and yeast in cerebrospinal fluid specimens. J Clin Microbiol 54: 2251–2261.
-
82.
Nelson RE, Stockmann C, Hersh AL, Pavia AT, Korgenksi K, Daly JA, Couturier MR, Ampofo K, Thorell EA, Doby EH, Robison JA, Blaschke AJ, 2015. Economic analysis of rapid and sensitive polymerase chain reaction testing in the emergency department for influenza infections in children. Pediatr Infect Dis J 34: 577–582.
-
83.
Xu M, Qin X, Astion ML, Rutledge JC, Simpson J, Jerome KR, Englund JA, Zerr DM, Migita RT, Rich S, Childs JC, Cent A, Del Beccaro MA, 2013. Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care. Am J Clin Pathol 139: 118–123.
-
84.
Weller SA, Bailey D, Matthews S, Lumley S, Sweed A, Ready D, Eltringham G, Richards J, Vipond R, Lukaszewski R, Payne PM, Aarons E, Simpson AJ, Hutley EJ, Brooks T, 2016. Evaluation of the Biofire FilmArray BioThreat-E Test (v2.5) for rapid identification of Ebola virus disease in heat-treated blood samples obtained in Sierra Leone and the United Kingdom. J Clin Microbiol 54: 114–119.
-
85.
Castan P, de Pablo A, Fernandez-Romero N, Rubio JM, Cobb BD, Mingorance J, Toro C, 2014. Point-of-care system for detection of Mycobacterium tuberculosis and rifampin resistance in sputum samples. J Clin Microbiol 52: 502–507.
-
86.
Shenai S, Armstrong DT, Valli E, Dolinger DL, Nakiyingi L, Dietze R, Dalcolmo MP, Nicol MP, Zemanay W, Manabe Y, Hadad DJ, Marques-Rodrigues P, Palaci M, Peres RL, Gaeddert M, Armakovitch S, Nonyane BA, Denkinger CM, Banada P, Joloba ML, Ellner J, Boehme C, Alland D, Dorman SE, 2016. Analytical and clinical evaluation of the Epistem Genedrive assay for detection of Mycobacterium tuberculosis. J Clin Microbiol 54: 1051–1057.
-
87.
Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, Allen J, Tahirli R, Blakemore R, Rustomjee R, Milovic A, Jones M, O'Brien SM, Persing DH, Ruesch-Gerdes S, Gotuzzo E, Rodrigues C, Alland D, Perkins MD, 2010. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med 363: 1005–1015.
-
88.
Semper AE, Broadhurst MJ, Richards J, Foster GM, Simpson AJH, Logue CH, Kelly JD, Miller A, Brooks TJG, Murray M, Pollock NR, 2016. Performance of the GeneXpert Ebola assay for diagnosis of Ebola virus disease in Sierra Leone: a field evaluation study. PLoS Med 13: e1001980.
-
89.
Van den Bergh R, Chaillet P, Sow MS, Amand M, van Vyve C, Jonckheere S, Crestani R, Sprecher A, Van Herp M, Chua A, Piriou E, Koivogui L, Antierens A, 2016. Feasibility of Xpert Ebola assay in Medecins Sans Frontieres ebola program, Guinea. Emerg Infect Dis 22: 210–216.
-
90.
Pantoja A, Kik SV, Denkinger CM, 2015. Costs of novel tuberculosis diagnostics–will countries be able to afford it? J Infect Dis 211 (Suppl 2): S67–S77.
-
91.
Wahrenbrock MG, Matushek S, Boonlayangoor S, Tesic V, Beavis KG, Charnot-Katsikas A, 2016. Comparison of Cepheid Xpert Flu/RSV XC and BioFire FilmArray for detection of influenza A, influenza B, and respiratory syncytial virus. J Clin Microbiol 54: 1902–1903.
-
92.
Gonzalez MD, Langley LC, Buchan BW, Faron ML, Maier M, Templeton K, Walker K, Popowitch EB, Miller MB, Rao A, Liebert UG, Ledeboer NA, Vinje J, Burnham CA, 2016. Multicenter evaluation of the Xpert norovirus assay for detection of norovirus genogroups I and II in fecal specimens. J Clin Microbiol 54: 142–147.
-
93.
Kurosaki Y, Magassouba NF, Oloniniyi OK, Cherif MS, Sakabe S, Takada A, Hirayama K, Yasuda J, 2016. Development and evaluation of reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assay coupled with a portable device for rapid diagnosis of Ebola virus disease in Guinea. PLoS Negl Trop Dis 10: e0004472.
-
94.
Patel JC, Lucchi NW, Srivastava P, Lin JT, Sug-Aram R, Aruncharus S, Bharti PK, Shukla MM, Congpuong K, Satimai W, Singh N, Udhayakumar V, Meshnick SR, 2014. Field evaluation of a real-time fluorescence loop-mediated isothermal amplification assay, RealAmp, for the diagnosis of malaria in Thailand and India. J Infect Dis 210: 1180–1187.
-
95.
Lu X, Li X, Mo Z, Jin F, Wang B, Zhao H, Shan X, Shi L, 2012. Rapid identification of chikungunya and dengue virus by a real-time reverse transcription-loop-mediated isothermal amplification method. Am J Trop Med Hyg 87: 947–953.
-
96.
Dittrich S, Castonguay-Vanier J, Moore CE, Thongyoo N, Newton PN, Paris DH, 2014. Loop-mediated isothermal amplification for Rickettsia typhi (the causal agent of murine typhus): problems with diagnosis at the limit of detection. J Clin Microbiol 52: 832–838.
-
97.
Kubo T, Agoh M, Mai LQ, Fukushima K, Nishimura H, Yamaguchi A, Hirano M, Yoshikawa A, Hasebe F, Kohno S, Morita K, 2010. Development of a reverse transcription-loop-mediated isothermal amplification assay for detection of pandemic (H1N1) 2009 virus as a novel molecular method for diagnosis of pandemic influenza in resource-limited settings. J Clin Microbiol 48: 728–735.
-
98.
Fukuda S, Takao S, Kuwayama M, Shimazu Y, Miyazaki K, 2006. Rapid detection of norovirus from fecal specimens by real-time reverse transcription-loop-mediated isothermal amplification assay. J Clin Microbiol 44: 1376–1381.
-
99.
Lee D, Kim EJ, Kilgore PE, Kim SA, Takahashi H, Ohnishi M, Anh DD, Dong BQ, Kim JS, Tomono J, Miyamoto S, Notomi T, Kim DW, Seki M, 2015. Clinical evaluation of a loop-mediated isothermal amplification (LAMP) assay for rapid detection of Neisseria meningitidis in cerebrospinal fluid. PLoS One 10: e0122922.
-
100.
Nagai K, Horita N, Yamamoto M, Tsukahara T, Nagakura H, Tashiro K, Shibata Y, Watanabe H, Nakashima K, Ushio R, Ikeda M, Narita A, Kanai A, Sato T, Kaneko T, 2016. Diagnostic test accuracy of loop-mediated isothermal amplification assay for Mycobacterium tuberculosis: systematic review and meta-analysis. Sci Rep 6: 39090.
-
101.
Greninger AL, Naccache SN, Federman S, Yu G, Mbala P, Bres V, Bouquet J, Stryke D, Somasekar S, Linnen J, Dodd R, Mulembakani P, Schneider B, Muyembe J-J, Stramer S, Chiu CY, 2015. Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis. Genome Med 7: 99.
-
102.
Hoenen T, Groseth A, Rosenke K, Fischer RJ, Hoenen A, Judson SD, Martellaro C, Falzarano D, Marzi A, Squires RB, Wollenberg KR, de Wit E, Prescott J, Safronetz D, van Doremalen N, Bushmaker T, Feldmann F, McNally K, Bolay FK, Fields B, Sealy T, Rayfield M, Nichol ST, Zoon KC, Massaquoi M, Munster VJ, Feldmann H, 2016. Nanopore Sequencing as a rapidly deployable Ebola outbreak tool. Emerg Infect Dis 22: 331.
-
103.
Quick J, Loman NJ, Duraffour S, Simpson JT, Severi E, Cowley L, Bore JA, Koundouno R, Dudas G, Mikhail A, Ouédraogo N, Afrough B, Bah A, Baum JHJ, Becker-Ziaja B, Boettcher JP, Cabeza-Cabrerizo M, Camino-Sánchez Á, Carter LL, Doerrbecker J, Enkirch T, Dorival IG, Hetzelt N, Hinzmann J, Holm T, Kafetzopoulou LE, Koropogui M, Kosgey A, Kuisma E, Logue CH, Mazzarelli A, Meisel S, Mertens M, Michel J, Ngabo D, Nitzsche K, Pallasch E, Patrono LV, Portmann J, Repits JG, Rickett NY, Sachse A, Singethan K, Vitoriano I, Yemanaberhan RL, Zekeng EG, Racine T, Bello A, Sall AA, Faye O, Faye O, Magassouba NF, Williams CV, Amburgey V, Winona L, Davis E, Gerlach J, Washington F, Monteil V, Jourdain M, Bererd M, Camara A, Somlare H, Camara A, Gerard M, Bado G, Baillet B, Delaune D, Nebie KY, Diarra A, Savane Y, Pallawo RB, Gutierrez GJ, Milhano N, Roger I, Williams CJ, Yattara F, Lewandowski K, Taylor J, Rachwal P, Turner DJ, Pollakis G, Hiscox JA, Matthews DA, Shea MKO, Johnston AM, Wilson D, Hutley E, Smit E, Di Caro A, Wölfel R, Stoecker K, Fleischmann E, Gabriel M, Weller SA, Koivogui L, Diallo B, Keïta S, Rambaut A, Formenty P, Günther S, Carroll MW, 2016. Real-time, portable genome sequencing for Ebola surveillance. Nature 530: 228–232.
-
104.
Oxford Nanopore Technologies, 2016. Everything Nanopore: MinION, PromethION, Kits and Consumables. Available at: https://store.nanoporetech.com/. Accessed December 16, 2016.
-
105.
Yehia N, Arafa AS, Abd El Wahed A, El-Sanousi AA, Weidmann M, Shalaby MA, 2015. Development of reverse transcription recombinase polymerase amplification assay for avian influenza H5N1 HA gene detection. J Virol Methods 223: 45–49.
-
106.
Chao C-C, Belinskaya T, Zhang Z, Ching W-M, 2015. Development of recombinase polymerase amplification assays for detection of Orientia tsutsugamushi or Rickettsia typhi. PLoS Negl Trop Dis 9: e0003884.
-
107.
Abd El Wahed A, Patel P, Faye O, Thaloengsok S, Heidenreich D, Matangkasombut P, Manopwisedjaroen K, Sakuntabhai A, Sall AA, Hufert FT, Weidmann M, 2015. Recombinase polymerase amplification assay for rapid diagnostics of dengue infection. PLoS One 10: e0129682.
-
108.
Yang M, Ke Y, Wang X, Ren H, Liu W, Lu H, Zhang W, Liu S, Chang G, Tian S, Wang L, Huang L, Liu C, Yang R, Chen Z, 2016. Development and evaluation of a rapid and sensitive EBOV-RPA test for rapid diagnosis of Ebola virus disease. Sci Rep 6: 26943.
-
109.
Boyle DS, McNerney R, Teng Low H, Leader BT, Pérez-Osorio AC, Meyer JC, O'Sullivan DM, Brooks DG, Piepenburg O, Forrest MS, 2014. Rapid detection of Mycobacterium tuberculosis by recombinase polymerase amplification. PLoS One 9: e103091.
-
110.
Crannell ZA, Cabada MM, Castellanos-Gonzalez A, Irani A, White AC, Richards-Kortum R, 2015. Recombinase polymerase amplification-based assay to diagnose Giardia in stool samples. Am J Trop Med Hyg 92: 583–587.
-
111.
Liu J, Ochieng C, Wiersma S, Stroher U, Towner JS, Whitmer S, Nichol ST, Moore CC, Kersh GJ, Kato C, Sexton C, Petersen J, Massung R, Hercik C, Crump JA, Kibiki G, Maro A, Mujaga B, Gratz J, Jacob ST, Banura P, Scheld WM, Juma B, Onyango CO, Montgomery JM, Houpt E, Fields B, 2016. Development of a TaqMan Array Card for acute-febrile-illness outbreak investigation and surveillance of emerging pathogens, including Ebola virus. J Clin Microbiol 54: 49–58.
-
112.
Kodani M, Yang G, Conklin LM, Travis TC, Whitney CG, Anderson LJ, Schrag SJ, Taylor TH, Beall BW, Breiman RF, Feikin DR, Njenga MK, Mayer LW, Oberste MS, Tondella MLC, Winchell JM, Lindstrom SL, Erdman DD, Fields BS, 2011. Application of TaqMan low-density arrays for simultaneous detection of multiple respiratory pathogens. J Clin Microbiol 49: 2175–2182.
-
113.
Liu J, Gratz J, Amour C, Kibiki G, Becker S, Janaki L, Verweij JJ, Taniuchi M, Sobuz SU, Haque R, Haverstick DM, Houpt ER, 2013. A laboratory-developed TaqMan Array Card for simultaneous detection of 19 enteropathogens. J Clin Microbiol 51: 472–480.
-
114.
Marx V, 2015. PCR heads into the field. Nat Methods 12: 393–397.
-
115.
Pardee K, Green AA, Takahashi MK, Braff D, Lambert G, Lee JW, Ferrante T, Ma D, Donghia N, Fan M, Daringer NM, Bosch I, Dudley DM, O'Connor DH, Gehrke L, Collins JJ, 2016. Rapid, low-cost detection of Zika virus using programmable biomolecular components. Cell 165: 1255–1266.
-
116.
Hopkins H, González IJ, Polley SD, Angutoko P, Ategeka J, Asiimwe C, Agaba B, Kyabayinze DJ, Sutherland CJ, Perkins MD, Bell D, 2013. Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda. J Infect Dis 208: 645–652.
-
117.
Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH, 2015. Analytical performance characteristics of the Cepheid GeneXpert Ebola assay for the detection of Ebola virus. PLoS One 10: e0142216.
-
118.
Theron G, Zijenah L, Chanda D, Clowes P, Rachow A, Lesosky M, Bara W, Mungofa S, Pai M, Hoelscher M, Dowdy D, Pym A, Mwaba P, Mason P, Peter J, Dheda K; TB-NEAT Team, 2014. Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial. Lancet 383: 424–435.
-
119.
Evans CA, 2011. GeneXpert—a game-changer for tuberculosis control? PLoS Med 8: e1001064.
-
120.
Drain PK, Garrett NJ, 2015. The arrival of a true point-of-care molecular assay-ready for global implementation? Lancet Glob Health 3: e663–e664.
-
121.
Mölsä M, Koskela KA, Rönkkö E, Ikonen N, Ziegler T, Nikkari S, 2012. Detection of influenza A viruses with a portable real-time PCR instrument. J Virol Methods 181: 188–191.
-
122.
Matero P, Hemmila H, Tomaso H, Piiparinen H, Rantakokko-Jalava K, Nuotio L, Nikkari S, 2011. Rapid field detection assays for Bacillus anthracis, Brucella spp., Francisella tularensis and Yersinia pestis. Clin Microbiol Infect 17: 34–43.
-
123.
Waggoner JJ, Gresh L, Mohamed-Hadley A, Ballesteros G, Davila MJ, Tellez Y, Sahoo MK, Balmaseda A, Harris E, Pinsky BA, 2016. Single-reaction multiplex reverse transcription PCR for detection of Zika, chikungunya, and dengue viruses. Emerg Infect Dis 22: 1295–1297.
-
124.
Centers for Disease Control and Prevention, 2016. Trioplex Real-Time RT-PCR Assay: Instructions for Use. Available at: http://www.fda.gov/downloads/MedicalDevices/Safety/EmergencySituations/UCM491592.pdf. Accessed July 15, 2016.
-
125.
Sharp SE, Hill CE, Valsamakis A, 2016. ASM, AMP and PASCV Express Concerns on New Molecular Test for Zika. Available at: http://www.asm.org/index.php/whatsnew-policy/137-policy/documents/statements-and-testimony/94652-zika-test-10-16. Accessed December 6, 2016.
-
126.
Glushakova LG, Bradley A, Bradley KM, Alto BW, Hoshika S, Hutter D, Sharma N, Yang Z, Kim MJ, Benner SA, 2015. High-throughput multiplexed xMAP Luminex array panel for detection of twenty two medically important mosquito-borne arboviruses based on innovations in synthetic biology. J Virol Methods 214: 60–74.
-
127.
Barzon L, Lavezzo E, Costanzi G, Franchin E, Toppo S, Palu G, 2013. Next-generation sequencing technologies in diagnostic virology. J Clin Virol 58: 346–350.
-
128.
Graf EH, Simmon KE, Tardif KD, Hymas W, Flygare S, Eilbeck K, Yandell M, Schlaberg R, 2016. Unbiased detection of respiratory viruses by use of RNA sequencing-based metagenomics: a systematic comparison to a commercial PCR panel. J Clin Microbiol 54: 1000–1007.
-
129.
Sardi S, Somasekar S, Naccache SN, Bandeira AC, Tauro LB, Campos GS, Chiu CY, 2016. Co-infections from Zika and chikungunya virus in Bahia, Brazil identified by metagenomic next-generation sequencing. J Clin Microbiol 54: 2348–2353.
-
130.
Yozwiak NL, Skewes-Cox P, Stenglein MD, Balmaseda A, Harris E, DeRisi JL, 2012. Virus identification in unknown tropical febrile illness cases using deep sequencing. PLoS Negl Trop Dis 6: e1485.
-
131.
Wilson MR, Naccache SN, Samayoa E, Biagtan M, Bashir H, Yu G, Salamat SM, Somasekar S, Federman S, Miller S, Sokolic R, Garabedian E, Candotti F, Buckley RH, Reed KD, Meyer TL, Seroogy CM, Galloway R, Henderson SL, Gern JE, DeRisi JL, Chiu CY, 2014. Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med 370: 2408–2417.
-
132.
McMullan LK, Folk SM, Kelly AJ, MacNeil A, Goldsmith CS, Metcalfe MG, Batten BC, Albarino CG, Zaki SR, Rollin PE, Nicholson WL, Nichol ST, 2012. A new phlebovirus associated with severe febrile illness in Missouri. N Engl J Med 367: 834–841.
-
133.
Stremlau MH, Andersen KG, Folarin OA, Grove JN, Odia I, Ehiane PE, Omoniwa O, Omoregie O, Jiang PP, Yozwiak NL, Matranga CB, Yang X, Gire SK, Winnicki S, Tariyal R, Schaffner SF, Okokhere PO, Okogbenin S, Akpede GO, Asogun DA, Agbonlahor DE, Walker PJ, Tesh RB, Levin JZ, Garry RF, Sabeti PC, Happi CT, 2015. Discovery of novel rhabdoviruses in the blood of healthy individuals from west Africa. PLoS Negl Trop Dis 9: e0003631.
-
134.
Kilianski A, Haas JL, Corriveau EJ, Liem AT, Willis KL, Kadavy DR, Rosenzweig CN, Minot SS, 2015. Bacterial and viral identification and differentiation by amplicon sequencing on the MinION nanopore sequencer. Gigascience 4: 12.
-
135.
Kilianski A, Roth PA, Liem AT, Hill JM, Willis KL, Rossmaier RD, Marinich AV, Maughan MN, Karavis MA, Kuhn JH, Honko AN, Rosenzweig CN, 2016. Use of unamplified RNA/cDNA-hybrid nanopore sequencing for rapid detection and characterization of RNA viruses. Emerg Infect Dis 22: 1448–1451.
-
136.
Benitez-Paez A, Portune K, Sanz Y, 2016. Species level resolution of 16S rRNA gene amplicons sequenced through MinION™ portable nanopore sequencer. GigaScience 5: 1–9.
-
137.
Backstedt BT, Buyuktanir O, Lindow J, Wunder EA Jr, Reis MG, Usmani-Brown S, Ledizet M, Ko A, Pal U, 2015. Efficient detection of pathogenic leptospires using 16S ribosomal RNA. PLoS One 10: e0128913.
-
138.
Tennant SM, Toema D, Qamar F, Iqbal N, Boyd MA, Marshall JM, Blackwelder WC, Wu Y, Quadri F, Khan A, Aziz F, Ahmad K, Kalam A, Asif E, Qureshi S, Khan E, Zaidi AK, Levine MM, 2015. Detection of typhoidal and paratyphoidal Salmonella in blood by real-time polymerase chain reaction. Clin Infect Dis 61 (Suppl 4): S241–S250.
-
139.
Head SR, Komori HK, LaMere SA, Whisenant T, Van Nieuwerburgh F, Salomon DR, Ordoukhanian P, 2014. Library construction for next-generation sequencing: overviews and challenges. Biotechniques 56: 61–64, 66, 68 passim.
-
140.
Mayxay M, Sengvilaipaseuth O, Chanthongthip A, Dubot-Peres A, Rolain JM, Parola P, Craig SB, Tulsiani S, Burns MA, Khanthavong M, Keola S, Pongvongsa T, Raoult D, Dittrich S, Newton PN, 2015. Causes of fever in rural southern Laos. Am J Trop Med Hyg 93: 517–520.
-
141.
Chandy S, Yoshimatsu K, Boorugu HK, Chrispal A, Thomas K, Peedicayil A, Abraham P, Arikawa J, Sridharan G, 2009. Acute febrile illness caused by hantavirus: serological and molecular evidence from India. Trans R Soc Trop Med Hyg 103: 407–412.
-
142.
Paris DH, Blacksell SD, Nawtaisong P, Jenjaroen K, Teeraratkul A, Chierakul W, Wuthiekanun V, Kantipong P, Day NP, 2011. Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute scrub typhus infection. PLoS Negl Trop Dis 5: e1307.
-
143.
Bingham AM, Cone M, Mock V, Heberlein-Larson L, Stanek D, Blackmore C, Likos A, 2016. Comparison of test results for Zika virus RNA in urine, serum, and saliva specimens from persons with travel-associated Zika virus disease—Florida, 2016. MMWR Morb Mortal Wkly Rep 65: 475–478.
-
144.
Zaas AK, Burke T, Chen M, McClain M, Nicholson B, Veldman T, Tsalik EL, Fowler V, Rivers EP, Otero R, Kingsmore SF, Voora D, Lucas J, Hero AO, Carin L, Woods CW, Ginsburg GS, 2013. A host-based RT-PCR gene expression signature to identify acute respiratory viral infection. Sci Transl Med 5: 203ra126.
-
145.
Kettler H, White K, Hawkes S, 2004. Mapping the landscape of diagnostics for sexually transmitted infections. Geneva, Switzerland: World Health Organization and TDR.
-
146.
Mabey D, Peeling RW, Ustianowski A, Perkins MD, 2004. Tropical infectious diseases: diagnostics for the developing world. Nat Rev Microbiol 2: 231–240.
-
147.
Peeling RW, Holmes KK, Mabey D, Ronald A, 2006. Rapid tests for sexually transmitted infections (STIs): the way forward. Sex Transm Infect 82: v1–v6.
-
148.
Ketema F, Zeh C, Edelman DC, Saville R, Constantine NT, 2001. Assessment of the performance of a rapid, lateral flow assay for the detection of antibodies to HIV. J Acquir Immune Defic Syndr 27: 63–70.
-
149.
Jarvis JN, Percival A, Bauman S, Pelfrey J, Meintjes G, Williams GN, Longley N, Harrison TS, Kozel TR, 2011. Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis. Clin Infect Dis 53: 1019–1023.
-
150.
Wilson ML, 2012. Malaria rapid diagnostic tests. Clin Infect Dis 54: 1637–1641.
-
151.
Yetisen AK, Akram MS, Lowe CR, 2013. Paper-based microfluidic point-of-care diagnostic devices. Lab Chip 13: 2210–2251.
-
152.
Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, Wong VL, Pohlmann RA, Ryan US, Whitesides GM, 2012. A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med 4: 152ra129.
-
153.
Gan W, Zhuang B, Zhang P, Han J, Li C-X, Liu P, 2014. A filter paper-based microdevice for low-cost, rapid, and automated DNA extraction and amplification from diverse sample types. Lab Chip 14: 3719–3728.
-
154.
Rodriguez NM, Linnes JC, Fan A, Ellenson CK, Pollock NR, Klapperich CM, 2015. Paper-based RNA extraction, in situ isothermal amplification, and lateral flow detection for low-cost, rapid diagnosis of Influenza A (H1N1) from clinical specimens. Anal Chem 87: 7872–7879.
-
155.
Connelly JT, Rolland JP, Whitesides GM, 2015. “Paper Machine” for molecular diagnostics. Anal Chem 87: 7595–7601.
-
156.
Houssin T, Cramer J, Grojsman R, Bellahsene L, Colas G, Moulet H, Minnella W, Pannetier C, Leberre M, Plecis A, Chen Y, 2016. Ultrafast, sensitive and large-volume on-chip real-time PCR for the molecular diagnosis of bacterial and viral infections. Lab Chip 16: 1401–1411.
-
157.
Son JH, Cho B, Hong S, Lee SH, Hoxha O, Haack AJ, Lee LP, 2015. Ultrafast photonic PCR. Light Sci Appl 4: e280.
-
158.
Wilson NO, Adjei AA, Anderson W, Baidoo S, Stiles JK, 2008. Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients. Am J Trop Med Hyg 78: 733–735.
-
159.
Korhonen EM, Huhtamo E, Virtala AM, Kantele A, Vapalahti O, 2014. Approach to non-invasive sampling in dengue diagnostics: exploring virus and NS1 antigen detection in saliva and urine of travelers with dengue. J Clin Virol 61: 353–358.
-
160.
Nie S, Benito-Pena E, Zhang H, Wu Y, Walt DR, 2013. Multiplexed salivary protein profiling for patients with respiratory diseases using fiber-optic bundles and fluorescent antibody-based microarrays. Anal Chem 85: 9272–9280.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1832 | 1377 | 65 |
| Full Text Views | 672 | 21 | 0 |
| PDF Downloads | 316 | 20 | 0 |