DzotsiEK, OheneSA, Asiedu-BekoeF, AmankwaJ, SarkodieB, AdjabengM, ThouphiqueAM, OfeiA, OduroJ, AtitogoD, BonneyJH, PaintsilSC, AmpofoW, 2012. The first cases of Lassa fever in Ghana. Ghana Med J46: 166&amp;#x2013;170.
DzotsiEKOheneSAAsiedu-BekoeFAmankwaJSarkodieBAdjabengMThouphiqueAMOfeiAOduroJAtitogoDBonneyJHPaintsilSCAmpofoW, 2012. The first cases of Lassa fever in Ghana. Ghana Med J46: 166&amp;#x2013;170.)| false
WolffS, SchultzeT, FehlingSK, MengelJP, KannG, WolfT, EickmannM, BeckerS, HainT, StreckerT, 2016. Genome sequence of Lassa virus isolated from the first domestically acquired case in Germany. Genome Announc4: e00938-16.
WolffSSchultzeTFehlingSKMengelJPKannGWolfTEickmannMBeckerSHainTStreckerT, 2016. Genome sequence of Lassa virus isolated from the first domestically acquired case in Germany. Genome Announc4: e00938-16.)| false
SafronetzD, SogobaN, LopezJE, MaigaO, DahlstromE, ZivcecM, FeldmannF, HaddockE, FischerRJ, AndersonJM, MunsterVJ, BrancoL, GarryR, PorcellaSF, SchwanTG, FeldmannH, 2013. Geographic distribution and genetic characterization of Lassa virus in sub-Saharan Mali. PLoS Negl Trop Dis7: e2582.
SafronetzDSogobaNLopezJEMaigaODahlstromEZivcecMFeldmannFHaddockEFischerRJAndersonJMMunsterVJBrancoLGarryRPorcellaSFSchwanTGFeldmannH, 2013. Geographic distribution and genetic characterization of Lassa virus in sub-Saharan Mali. PLoS Negl Trop Dis7: e2582.)| false
Previously, we reported a high seroprevalence rate of Lassa virus antibodies in inhabitants of three villages in southern Mali where infected rodents have been demonstrated. Herein, we report a 1-year follow-up study in which we were able to collect a second blood samples from 88.7&amp;amp;#x0025; of participants of the same cohort. We identified 23 seroconversions for IgG antibodies reactive against Lassa virus, representing an incidence of 6.3&amp;amp;#x0025; (95&amp;amp;#x0025; confidence interval &amp;amp;#x003D; 3.8&amp;amp;#x2013;8.8&amp;amp;#x0025;). Seroconversion was frequently seen in preteenage children (12/23, 51.7&amp;amp;#x0025;) and two household/familial clusters were identified. These results confirm active transmission of Lassa virus is occurring in southern Mali and appropriate diagnostic testing should be established for this etiological agent of severe viral hemorrhagic fever.
&amp;amp;#x002A; Address correspondence to Heinz Feldmann, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840. E-mail: firstname.lastname@example.org
Financial support: This work was funded by the International Centers for Excellence in Research program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, with travel support from the Public Health Agency of Canada.