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Progressive Perforation of the Nasal Septum Due to Leishmania major: A Case of Mucosal Leishmaniasis in a Traveler

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  • 1 Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
  • | 2 Institute for Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria.
  • | 3 Department for Otorhinolaryngology-Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.
  • | 4 Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
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This report describes a case of mucosal leishmaniasis caused by Leishmania major with destructive perforation of the nasal septum illustrating the diagnostic challenges of a rare clinical presentation of L. major infection in a traveler. The atypical presentation may have been associated with the use of cortisone as a potential trigger for the progressive destruction of the nasal septum.

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Author Notes

* Address correspondence to Michael Ramharter, Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. E-mail: michael.ramharter@meduniwien.ac.at

Consent for publication: The patient has provided written informed consent for publication of this case report.

Authors' addresses: Nicole Harrison, Luzia Veletzky, and Heimo Lagler, Division of Infectious Diseases and Tropical Medicine Department of Medicine I, Medical University of Vienna, Vienna, Austria, E-mails: nicole.harrison@meduniwien.ac.at, n1042220@students.meduniwien.ac.at, and heimo.lagler@meduniwien.ac.at. Julia Walochnik, Institute for Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, Austria, E-mail: julia.walochnik@meduniwien.ac.at, Reinhard Ramsebner, Department for Otorhinolaryngology-Head and Neck Surgery, Medical University of Vienna, Vienna, Austria, E-mail: reinhard.ramsebner@meduniwien.ac.at. Michael Ramharter, Division of Infectious Diseases and Tropical Medicine Department of Medicine I, Medical University of Vienna, Vienna, Austria, and Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany, E-mail: michael.ramharter@meduniwien.ac.at.

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