United Nations System Standing Committee on Nutrition, 2010. Sixth Report on the World Nutrition. Geneva: United Nations.
Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T, 2006. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev 64: S34–S43.
Jukes M, 2005. The long-term impact of preschool health and nutrition on education. Food Nutr Bull 26: S193–S201.
Ozdemir N, 2015. Iron deficiency anemia: from diagnosis to treatment in children. Turk Pediatri Ars 50: 11–19.
Crawley J, 2004. Reducing the burden of anemia in infants and young children in malaria-endemic countries of Africa: from evidence to action. Am J Trop Med Hyg 71 (2 Suppl): 25–34.
Friedman JF, Kanzaria HK, McGarvey ST, 2005. Human schistosomiasis and anemia: the relationship and potential mechanisms. Trends Parasitol 21: 386–392.
Colley DG, Bustinduy AL, Secor WE, King CH, 2014. Human schistosomiasis. Lancet 383: 2253–2264.
Kassebaum NJ, Jasrasaria R, Naghavi M, Wulf SK, Johns N, Lozano R, Regan M, Weatherall D, Chou DP, Eisele TP, Flaxman SR, Pullan RL, Brooker SJ, Murray CJL, 2014. A systematic analysis of global anemia burden from 1990 to 2010. Blood 123: 615–624.
Petti CA, Polage CR, Quinn TC, Ronald AR, Sande MA, 2006. Laboratory medicine in Africa: a barrier to effective health care. Clin Infect Dis 42: 377–382.
Grietens KP, Ribera JM, Erhart A, Hoibak S, Ravinetto RM, Gryseels C, Dierickx S, O'Neill S, Muela SH, D'Alessandro U, 2014. Doctors and vampires in sub-Saharan Africa: ethical challenges in clinical trial research. Am J Trop Med Hyg 91: 213–215.
Causey MW, Miller S, Foster A, Beekley A, Zenger D, Martin M, 2011. Validation of noninvasive hemoglobin measurements using the Masimo Radical-7 SpHb Station. Am J Surg 201: 592–598.
Gayat E, Aulagnier J, Matthieu E, Boisson M, Fischler M, 2012. Non-invasive measurement of hemoglobin: assessment of two different point-of-care technologies. PLoS One 7: e30065.
Shah N, Osea EA, Martinez GJ, 2014. Accuracy of noninvasive hemoglobin and invasive point-of-care hemoglobin testing compared with a laboratory analyzer. Int J Lab Hematol 36: 56–61.
Ardin S, Stormer M, Radojska S, Oustianskaia L, Hahn M, Gathof BS, 2015. Comparison of three noninvasive methods for hemoglobin screening of blood donors. Transfusion 55: 379–387.
Hsu DP, French AJ, Madson SL, Palmer JM, Gidvani-Diaz V, 2016. Evaluation of a noninvasive hemoglobin measurement device to screen for anemia in infancy. Matern Child Health J 20: 827–832.
Hiscock R, Kumar D, Simmons SW, 2015. Systematic review and meta-analysis of method comparison studies of Masimo pulse co-oximeters (Radical-7 or Pronto-7) and HemoCue(R) absorption spectrometers (B-Hemoglobin or 201+) with laboratory haemoglobin estimation. Anaesth Intensive Care 43: 341–350.
Righetti AA, Koua AYG, Adiossan LG, Glinz D, Hurrell RF, N'Goran EK, Niamké S, Wegmüller R, Utzinger J, 2012. Etiology of anemia among infants, school-aged children, and young non-pregnant women in different settings of south-central Côte d'Ivoire. Am J Trop Med Hyg 87: 425–434.
Cable RG, Steele WR, Melmed RS, Johnson B, Mast AE, Carey PM, Kiss JE, Kleinman SH, Wright DJ, 2012. The difference between fingerstick and venous hemoglobin and hematocrit varies by sex and iron stores. Transfusion 52: 1031–1040.
Nkrumah B, Nguah SB, Sarpong N, Dekker D, Idriss A, May J, Adu-Sarkodie Y, 2011. Hemoglobin estimation by the HemoCue(R) portable hemoglobin photometer in a resource poor setting. BMC Clin Pathol 11: 5.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 25 | 25 | 8 |
Full Text Views | 449 | 91 | 1 |
PDF Downloads | 101 | 18 | 0 |
Anemia remains a major public health issue in many African communities. We compared a novel, commercially available noninvasive hemoglobin (Hb)–measuring device to direct Hb measurements by finger-prick samples in a pediatric cohort in rural Côte d'Ivoire. Noninvasive Hb measurements were attempted in 191 children 2–15 years of age and obtained in 102 (53.5%) children. The median Hb for the 102 children was 12.0 g/dL (interquartile range [IQR] = 11.3–12.7 g/dL) for conventional absorptiometry and 13.3 g/dL (IQR = 12.1–14.2 g/dL) for noninvasive measurements. A Bland–Altman analysis demonstrated a median bias of +1.1 g/dL (IQR = 0.4–2.0 g/dL), with greater overestimation of Hb by noninvasive testing occurring at low Hb values. This overestimation of the noninvasive Hb–measuring device to direct Hb measurements persisted across preschool- and school-aged children, and both sexes. The Pearson correlation coefficient was 0.50 for children 4–9 years of age, and 0.33 for children 10–15 years of age. Further study and development of noninvasive Hb devices is necessary prior to implementation in African pediatric populations.
Financial support: Jennifer Keiser is grateful to the European Research Council for financial support (ERC-2013-CoG 614739-A_HERO).
Authors' addresses: Isaac I. Bogoch, Divisions of General Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Canada, E-mail: isaac.bogoch@uhn.ca. Jean T. Coulibaly, Unité de Formation et de Recherche Biosciences, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, E-mail: couljeanvae@yahoo.fr. Jason Rajchgot, Department of Medicine, University of Toronto, Toronto, Canada, E-mail: jason.rajchgot@mail.utoronto.ca. Jason R. Andrews, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, E-mail: jandr@stanford.edu. Jana Kovac, Gordana Panic, and Jennifer Keiser, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland, E-mails: jana.kovac@unibas.ch, gordana.panic@unibas.ch, and jennifer.keiser@unibas.ch. Jürg Utzinger, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland, E-mail: juerg.utzinger@unibas.ch.
United Nations System Standing Committee on Nutrition, 2010. Sixth Report on the World Nutrition. Geneva: United Nations.
Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T, 2006. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev 64: S34–S43.
Jukes M, 2005. The long-term impact of preschool health and nutrition on education. Food Nutr Bull 26: S193–S201.
Ozdemir N, 2015. Iron deficiency anemia: from diagnosis to treatment in children. Turk Pediatri Ars 50: 11–19.
Crawley J, 2004. Reducing the burden of anemia in infants and young children in malaria-endemic countries of Africa: from evidence to action. Am J Trop Med Hyg 71 (2 Suppl): 25–34.
Friedman JF, Kanzaria HK, McGarvey ST, 2005. Human schistosomiasis and anemia: the relationship and potential mechanisms. Trends Parasitol 21: 386–392.
Colley DG, Bustinduy AL, Secor WE, King CH, 2014. Human schistosomiasis. Lancet 383: 2253–2264.
Kassebaum NJ, Jasrasaria R, Naghavi M, Wulf SK, Johns N, Lozano R, Regan M, Weatherall D, Chou DP, Eisele TP, Flaxman SR, Pullan RL, Brooker SJ, Murray CJL, 2014. A systematic analysis of global anemia burden from 1990 to 2010. Blood 123: 615–624.
Petti CA, Polage CR, Quinn TC, Ronald AR, Sande MA, 2006. Laboratory medicine in Africa: a barrier to effective health care. Clin Infect Dis 42: 377–382.
Grietens KP, Ribera JM, Erhart A, Hoibak S, Ravinetto RM, Gryseels C, Dierickx S, O'Neill S, Muela SH, D'Alessandro U, 2014. Doctors and vampires in sub-Saharan Africa: ethical challenges in clinical trial research. Am J Trop Med Hyg 91: 213–215.
Causey MW, Miller S, Foster A, Beekley A, Zenger D, Martin M, 2011. Validation of noninvasive hemoglobin measurements using the Masimo Radical-7 SpHb Station. Am J Surg 201: 592–598.
Gayat E, Aulagnier J, Matthieu E, Boisson M, Fischler M, 2012. Non-invasive measurement of hemoglobin: assessment of two different point-of-care technologies. PLoS One 7: e30065.
Shah N, Osea EA, Martinez GJ, 2014. Accuracy of noninvasive hemoglobin and invasive point-of-care hemoglobin testing compared with a laboratory analyzer. Int J Lab Hematol 36: 56–61.
Ardin S, Stormer M, Radojska S, Oustianskaia L, Hahn M, Gathof BS, 2015. Comparison of three noninvasive methods for hemoglobin screening of blood donors. Transfusion 55: 379–387.
Hsu DP, French AJ, Madson SL, Palmer JM, Gidvani-Diaz V, 2016. Evaluation of a noninvasive hemoglobin measurement device to screen for anemia in infancy. Matern Child Health J 20: 827–832.
Hiscock R, Kumar D, Simmons SW, 2015. Systematic review and meta-analysis of method comparison studies of Masimo pulse co-oximeters (Radical-7 or Pronto-7) and HemoCue(R) absorption spectrometers (B-Hemoglobin or 201+) with laboratory haemoglobin estimation. Anaesth Intensive Care 43: 341–350.
Righetti AA, Koua AYG, Adiossan LG, Glinz D, Hurrell RF, N'Goran EK, Niamké S, Wegmüller R, Utzinger J, 2012. Etiology of anemia among infants, school-aged children, and young non-pregnant women in different settings of south-central Côte d'Ivoire. Am J Trop Med Hyg 87: 425–434.
Cable RG, Steele WR, Melmed RS, Johnson B, Mast AE, Carey PM, Kiss JE, Kleinman SH, Wright DJ, 2012. The difference between fingerstick and venous hemoglobin and hematocrit varies by sex and iron stores. Transfusion 52: 1031–1040.
Nkrumah B, Nguah SB, Sarpong N, Dekker D, Idriss A, May J, Adu-Sarkodie Y, 2011. Hemoglobin estimation by the HemoCue(R) portable hemoglobin photometer in a resource poor setting. BMC Clin Pathol 11: 5.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 25 | 25 | 8 |
Full Text Views | 449 | 91 | 1 |
PDF Downloads | 101 | 18 | 0 |