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Human immunodeficiency virus (HIV) and dengue coinfection has not been extensively studied. We report herein a case of dengue serotype 1 infection in an HIV-1-positive patient coinfected with hepatitis B virus (HBV) in Colima State, Mexico. CD4+ cells and HIV-1 viremia remained at normal levels, and no severe complications were observed during this multiple viral infection. The alanine transaminase and aspartate transaminase values were elevated before and during dengue infection. Surprisingly, these parameters were significantly reduced 2 months later. Because of the lack of evidence regarding this multiple viral interaction, further research is required to understand the biologic and clinical course of dengue infection in HIV-1/HBV coinfected patients, especially in tropical regions where dengue virus transmission is highly active.
Authors' addresses: Iván Delgado-Enciso, School of Medicine, Public Health, University of Colima, Colima, México and State Cancer Institute, Department of Health, Colima, México, E-mail: email@example.com. Francisco Espinoza-Gómez, School of Medicine, Public Health, University of Colima, Avenida Universidad 333, Colima, México and Department of Internal Medicine, Regional Hospital of Colima, Department of Health, Colima, México, Email: firstname.lastname@example.org. Rodolfo Ochoa-Jiménez, Department of Internal Medicine, Regional Hospital of Colima, Department of Health, Colima, México, E-mail: email@example.com. Salvador Valle-Reyes and Clemente Vásquez, School of Medicine, Public Health, University of Colima, Avenida Universidad 333, Colima, Mexico, E-mails: firstname.lastname@example.org and email@example.com. Uriel A. López-Lemus, School of Medicine, Public Health, University of Colima, Avenida Universidad 333, Colima, Mexico and Biomedical Sciences, University of Colima, Colima, Mexico, E-mail: firstname.lastname@example.org.