• 1.

    Chen J, Chen Z, Lin J, Zhu G, Meng H, Cui G, Wu N, Hu R, Pan J, Zou Y, Feng H, 2013. Cerebral paragonimiasis: a retrospective analysis of 89 cases. Clin Neurol Neurosurg 115: 546551.

    • Search Google Scholar
    • Export Citation
  • 2.

    Xia Y, Ju Y, Chen J, You C, 2015. Cerebral paragonimiasis: a retrospective analysis of 27 cases. J Neurosurg Pediatr 15: 101106.

  • 3.

    Oh SJ, 1969. Cerebral paragonimiasis. J Neurol Sci 8: 2748.

  • 4.

    Kusner DJ, King CH, 1993. Cerebral paragonimiasis. Semin Neurol 13: 201208.

  • 5.

    Chai JY, 2013. Paragonimiasis. Handb Clin Neurol 114: 283296.

  • 6.

    Centers for Disease Control and Prevention, 2010. Human paragonimiasis after eating raw or undercooked crayfish—Missouri, July 2006–September 2010. MMWR 59: 15731576.

    • Search Google Scholar
    • Export Citation
  • 7.

    Slesak G, Inthalad S, Basy P, Keomanivong D, Phoutsavath O, Khampoui S, Grosrenaud A, Amstutz V, Barennes H, Buisson Y, Odermatt P, 2011. Ziehl-Neelsen staining technique can diagnose paragonimiasis. PLoS Negl Trop Dis 5: e1048.

    • Search Google Scholar
    • Export Citation
  • 8.

    Cho SY, Kong Y, Yun DH, Kang SY, Kim LS, Chung YB, Yang HJ, 2000. Persisting antibody reaction in paragonimiasis after praziquantel treatment is elicited mainly by egg antigens. Korean J Parasitol 38: 7584.

    • Search Google Scholar
    • Export Citation
  • 9.

    Sugiyama H, Morishima Y, Rangsiruji A, Binchai S, Ketudat P, Kawanaka M, 2006. Application of multiplex PCR for species discrimination using individual metacercariae of Paragonimus occurring in Thailand. Southeast Asian J Trop Med Public Health 37 (Suppl 3): 4852.

    • Search Google Scholar
    • Export Citation
  • 10.

    Kang S-Y, Kim T-K, Kim TY, Ha Y-I, Choi S-W, Hong S-J, 2000. A case of chronic cerebral Paragonimiasis westermani. Korean J Parasitol 38: 167171.

 
 
 

 

 

 

 

 

 

Cerebral Paragonimiasis Presenting with Sudden Death

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  • 1 Department of Pathology, University of California San Diego School of Medicine, La Jolla, California.
  • | 2 Department of Medicine, University of California San Diego School of Medicine, La Jolla, California.
  • | 3 Department of Molecular Pathology, Cleveland Clinic, Cleveland, Ohio.
  • | 4 Department of the Medical Examiner, San Diego County, Medical Examiner's Office, San Diego, California.

Abstract

A 58-year-old Korean-born woman with a history of seizures and psychiatric issues was found dead at home. Autopsy was notable for large, calcified nodules that had nearly replaced her right temporal lobe. Histologic examination revealed the presence of Paragonimus eggs. This case demonstrates a rare manifestation of an aberrantly migrated lung fluke that resulted in epilepsy and sudden death years after the initial infection.

Author Notes

* Address correspondence to Sharon L. Reed, Department of Pathology, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0612. E-mail: slreed@ucsd.edu† These authors contributed equally to this work.

Authors' addresses: Deirdre E. Amaro, Sheriff-Coroner's Office, Redding, CA, E-mail: damaro@ucsd.edu. Annie Cowell, Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, E-mail: acowell@ucsd.edu. Marion J. Tuohy and Gary W. Procop, Department of Molecular Pathology, Cleveland Clinic, Cleveland, OH, E-mails: tuohym@ccf.org and procopg@ccf.org. Jacquelyn Morhaime, Department of the Medical Examiner, San Diego County, Medical Examiner's Office, San Diego, CA, E-mail: jacquelyn.morhaime@sdcounty.ca.gov. Sharon L. Reed, Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, and Department of Pathology, University of California San Diego School of Medicine, La Jolla, CA, E-mail: slreed@ucsd.edu.

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