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Spotted Fever Group Rickettsioses and Murine Typhus in a Malaysian Teaching Hospital

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  • 1 Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
  • | 2 Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Limited information is available on the etiological agents of rickettsioses in southeast Asia. Herein, we report the molecular investigation of rickettsioses in four patients attending a teaching hospital in Malaysia. DNA of Rickettsia sp. RF2125, Rickettsia typhi, and a rickettsia closely related to Rickettsia raoultii was detected in the blood samples of the patients. Spotted fever group rickettsioses and murine typhus should be considered in the diagnosis of patients with nonspecific febrile illness in this region.

Author Notes

* Address correspondence to Sun Tee Tay, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia, E-mail: tayst@um.edu.my and Sasheela Ponnampalavanar, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia, E-mail: sasheela@um.edu.my.

Financial support: This study was funded by High Impact Research Grants (UM.C/625/1/HIR-MOHE/CHAN/11 and E000013-20001 [subprogramme-4]), University Malaya Research Grant (RP013-2012A), and Postgraduate Research Fund (PG006-2013B) from University of Malaya, Kuala Lumpur, Malaysia.

Authors' addresses: Kai Ling Kho, Fui Xian Koh, Harvinder Kaur Lakhbeer Singh, Hafizatul Anis Mohamed Zan, and Sun Tee Tay, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, E-mails: khokailing@yahoo.com, fuixian@gmail.com, harvinder@ummc.edu.my, anismz@um.edu.my, and tayst@um.edu.my. Anjanna Kukreja and Sasheela Ponnampalavanar, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, E-mails: anjanna86@yahoo.com and sasheela@um.edu.my.

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