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Infection with Leptospira kirschneri Serovar Mozdok: First Report from the Southern Hemisphere

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  • Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, Brazil; Faculdade de Veterinária, Universidade Federal de Pelotas, Pelotas, Brazil

Leptospirosis is a global zoonosis caused by pathogenic Leptospira spp. In this study, we characterized two Leptospira kirschneri serogroup Pomona serovar Mozdok isolates, one obtained from a dog and the other from a patient with severe leptospirosis, 4 years later. Histopathological analysis showed that both isolates caused severe tissue damage when used to infect hamsters. While L. kirschneri serogroup Pomona serovar Mozdok is endemic in animals in Europe, there is only one report of human leptospirosis in the literature. Although strains belonging to L. kirschneri serogroup Pomona have been identified in cases of human leptospirosis in Europe, serovar Mozdok has not yet been implicated. The 4-year interval between isolations and the fact that this is the first report of serovar Mozdok as the causative agent of human leptospirosis in the southern hemisphere, demonstrates its epidemiological importance to public health. Moreover, the presence of serovar Mozdok in Brazil has the potential to affect vaccine and diagnostic test development.

Author Notes

* Address correspondence to Odir Antonio Dellagostin, Núcleo de Biotecnologia, Centro de Desenvolvimento Tecnológico, Campus Universitário s/n, Caixa Postal 354, 96010-900, Pelotas, Brazil. E-mail: odir@ufpel.edu.br

Financial support: The funding and scholarships were provided by CNPq and CAPES.

Authors' addresses: Carlos Eduardo Pouey da Cunha, Centro de Desenvolvimento Tecnológico, Núcleo de Biotecnologia, Universidade Federal de Pelotas, Pelotas, Brazil, E-mail: cpouey@gmail.com. Samuel Rodrigues Felix, Amilton Clair Pinto Seixas Neto, Anelize Campello-Felix, Márcia de Oliveira Nobre, and Éverton Fagonde da Silva, Faculdade de Veterinária, Universidade Federal de Pelotas, Pelotas, Brazil, E-mails: samuelrf@gmail.com, amiltonseixas@gmail.com, anelizecampellofelix@gmail.com, marciaonobre@gmail.com, and fagondee@gmail.com. Frederico Schmitt Kremer, Leonardo Garcia Monte, Marta Gonçalves Amaral, Cláudia Pinho Hartleben, Alan John Alexander McBride, and Odir Antonio Dellagostin, Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, Brazil, E-mails: fred.s.kremer@gmail.com, leonardogmonte@hotmail.com, martagamaral@gmail.com, hartlebenclaudia@gmail.com, alanmcb@gmail.com, and odirad@terra.com.br.

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