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Evidence of Apeu Virus Infection in Wild Monkeys, Brazilian Amazon

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  • Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Minas Gerais, Brazil

Orthobunyaviruses are arboviruses in which at least 30 members are human pathogens. The members of group C orthobunyaviruses were first isolated in the Brazilian Amazon in 1950, since that time little information is accumulated about ecology and the medical impact of these virus groups in Brazil. Herein, we describe the evidence of Apeu virus (APEUV; an Orthobunyavirus member) infection in wild monkeys from the Brazilian Amazon forest. APEUV was detected by using a neutralizing antibody in serum and its RNA, suggesting past and acute infection of Amazonian monkeys by this virus. These results altogether represent an important contribution of orthobunyavirus ecology in the Amazon and an update about recent circulation and risk for humans with expansion of the cities to Amazon forest.

Author Notes

* Address correspondence to Jônatas S. Abrahão, Laboratório de Virus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627, Caixa Postal 486, 31270-901, Belo Horizonte, Minas Gerais, Brazil. E-mail: jonatas.abrahao@gmail.com† These authors contributed equally to this work.

Financial support: This study was supported by the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG). Danilo B. Oliveira received fellowships from CNPq, and Ana Paula Moreira Franco-Luiz received financial support from CAPES. Erna G. Kroon, Carla Amaral Bonjardim, Gilane S. Trindade, and Paulo C. P. Ferreira are researchers from CNPq.

Authors' addresses: Danilo B. Oliveira, Ana Paula Moreira Franco Luiz, Alexandre Fagundes, Carla Amaral Pinto, Cláudio A. Bonjardim, Giliane S. Trindade, Erna G. Kroon, Jônatas S. Abrahão, and Paulo C. P. Ferreira, Laboratório de Virus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Minas Gerais, Brazil, E-mails: danilobretas@yahoo.com.br, anapaulamluiz@gmail.com, alexandre210490@yahoo.com.br, carlaamaral@gmail.com, claudio.bonjardim@pq.cnpq.br, giliane@icb.ufmg.br, kroone@icb.ufmg.br, jonatas.abrahao@gmail.com, and peregrinopcp@hotmail.com.

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