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Prevalence and Distribution of Leishmania RNA Virus 1 in Leishmania Parasites from French Guiana

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  • Ecosystèmes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Cayenne, French Guiana; Laboratoire Associé–Centre National de Référence Leishmania, Laboratory of Parasitology and Mycology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Immunology Laboratory of Leishmaniasis, Pasteur Institute of French Guiana, Cayenne, French Guiana; Laboratory of Virus-Host Interactions, Pasteur Institute of French Guiana, Cayenne, French Guiana; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland; Guianan Institute of Tropical Dermatology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana; Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane, Cayenne General Hospital, Cayenne, French Guiana; Laboratory of Parasitology and Mycology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana
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In South America, the presence of the Leishmania RNA virus type 1 (LRV1) was described in Leishmania guyanensis and Leishmania braziliensis strains. The aim of this study was to determine the prevalence distribution of LRV1 in Leishmania isolates in French Guiana given that, in this French overseas department, most Leishmania infections are due to these parasite species. The presence of the virus was observed in 74% of Leishmania spp. isolates, with a highest presence in the internal areas of the country.

Author Notes

* Address correspondence to Marine Ginouvès, Ecosystèmes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Campus Saint Denis, Avenue d'Estrees, Cayenne 97300, French Guiana. E-mail: marine.ginouves@univ-guyane.fr

Financial support: This work was supported by the University of the French West Indies and French Guiana and the Ministère Français de l'Enseignement Supérieur et de la Recherche Scientifique. It has benefited from an Investissement d'Avenir grant managed by Agence Nationale de la Recherche (CEBA, reference no. ANR-10-LABX-25-01).

Conflict of interest: Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

Authors' addresses: Marine Ginouvès and Stéphane Simon, Ecosystèmes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Cayenne, French Guiana, and Laboratoire Associé–Centre National de Référence Leishmania, Laboratory of Parasitology and Mycology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, E-mails: marine.ginouves@univ-guyane.fr and stephane.simon@guyane.univ-ag.fr. Eliane Bourreau, Immunology Laboratory of Leishmaniasis, Pasteur Institute of French Guiana, Cayenne, French Guiana, E-mail: ebourreau@pasteur-cayenne.fr. Vincent Lacoste, Laboratory of Virus Hosts Interaction, Pasteur Institute of French Guiana, Cayenne, French Guiana, E-mail: vlacoste@pasteur-cayenne.fr. Catherine Ronet, Department of Biochemistry, University of Lausanne, Epalinges, Switzerland, E-mail: catherine.ronet@unil.ch. Pierre Couppié, Ecosystemes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Cayenne, French Guiana, and Guianan Institute of Tropical Dermatology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, E-mail: pierre.couppie@ch-cayenne.fr. Mathieu Nacher, Ecosystemes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Cayenne, French Guiana, and Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane, Cayenne General Hospital, Cayenne, French Guiana, E-mail: mathieu.nacher@ch-cayenne.fr. Magalie Demar, Ecosystemes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Cayenne, French Guiana, Laboratoire Associé–Centre National de Référence Leishmania, Laboratory of Parasitology and Mycology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, and Laboratory of Parasitology and Mycology, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana, E-mail: magalie.demar@ch-cayenne.fr. Ghislaine Prévot, Ecosystemes Amazoniens et Pathologie Tropicale–EA 3593–Labex CEBA–Medicine Department, University of French Guiana, Cayenne, French Guiana, E-mail: fac.prevot@gmail.com.

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