• 1.

    Liu P, Bu QN, Wang L, Han J, Du RJ, Lei YX, Ouyang YQ, Li J, Zhu YH, Lu FM, Zhuang H, 2013. Transmission of hepatitis E virus from rabbits to cynomolgus macaques. Emerg Infect Dis 19: 559565.

    • Search Google Scholar
    • Export Citation
  • 2.

    Dai X, Dong C, Zhou Z, Liang J, Dong M, Yang Y, Fu J, Tian H, Wang S, Fan J, Meng J, Purdy MA, 2013. Hepatitis E virus genotype 4, Nanjing, China, 2001–2011. Emerg Infect Dis 19: 15281530.

    • Search Google Scholar
    • Export Citation
  • 3.

    Kamar N, Abravanel F, Selves J, Garrouste C, Esposito L, Lavayssiere L, Cointault O, Ribes D, Cardeau I, Nogier MB, Mansuy JM, Muscari F, Peron JM, Izopet J, Rostaing L, 2010. Influence of immunosuppressive therapy on the natural history of genotype 3 hepatitis-E virus infection after organ transplantation. Transplantation 89: 353360.

    • Search Google Scholar
    • Export Citation
  • 4.

    Yugo DM, Meng XJ, 2013. Hepatitis E virus: foodborne, waterborne and zoonotic transmission. Int J Environ Res Public Health 10: 45074533.

  • 5.

    Pavio N, Meng XJ, Doceul V, 2015. Zoonotic origin of hepatitis E. Curr Opin Virol 10: 3441.

  • 6.

    Di Martino B, Di Profio F, Martella V, Di Felice E, Di Francesco CE, Ceci C, Marsilio F, 2010. Detection of hepatitis E virus in slaughtered pigs in Italy. Arch Virol 155: 103106.

    • Search Google Scholar
    • Export Citation
  • 7.

    Carpentier A, Chaussade H, Rigaud E, Rodriguez J, Berthault C, Boue F, Tognon M, Touzé A, Garcia-Bonnet N, Choutet P, Coursaget P, 2012. High hepatitis E virus seroprevalence in forestry workers and in wild boars in France. J Clin Microbiol 50: 28882893.

    • Search Google Scholar
    • Export Citation
  • 8.

    Traore KA, Rouamba H, Nebie Y, Sanou M, Traore AS, Barro N, Roques P, 2012. Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso. PLoS One 7: e48125.

    • Search Google Scholar
    • Export Citation
  • 9.

    Barnaud E, Rogee S, Garry P, Rose N, Pavio N, 2012. Thermal inactivation of infectious hepatitis E virus in experimentally contaminated food. Appl Environ Microbiol 78: 51535159.

    • Search Google Scholar
    • Export Citation
  • 10.

    Cooper K, Huang FF, Batista L, Rayo CD, Bezanilla JC, Toth TE, Meng XJ, 2005. Identification of genotype 3 hepatitis E virus (HEV) in serum and fecal samples from pigs in Thailand and Mexico, where genotype 1 and 2 HEV strains are prevalent in the respective human populations. J Clin Microbiol 43: 16841688.

    • Search Google Scholar
    • Export Citation
  • 11.

    Temmam S, Besnard L, Andriamandimby SF, Foray C, Rasamoelina-Andriamanivo H, Heraud JM, Cardinale E, Dellagi K, Pavio N, Pascalis H, Porphyre V, 2013. High prevalence of hepatitis E in humans and pigs and evidence of genotype-3 virus in swine, Madagascar. Am J Trop Med Hyg 88: 329338.

    • Search Google Scholar
    • Export Citation
  • 12.

    Krumbholz A, Mohn U, Lange J, Motz M, Wenzel JJ, Jilg W, Walther M, Straube E, Wutzler P, Zell R, 2012. Prevalence of hepatitis E virus-specific antibodies in humans with occupational exposure to pigs. Med Microbiol Immunol (Berl) 201: 239244.

    • Search Google Scholar
    • Export Citation
  • 13.

    Adjei AA, Aviyase JT, Tettey Y, Adu-Gyamfi C, Mingle JA, Ayeh-Kumi PF, Adiku TK, Gyasi RK, 2009. Hepatitis E virus infection among pig handlers in Accra, Ghana. East Afr Med J 86: 359363.

    • Search Google Scholar
    • Export Citation
  • 14.

    Pavio N, Meng XJ, Renou C, 2010. Zoonotic hepatitis E: animal reservoirs and emerging risks. Vet Res 41: 46.

  • 15.

    Owolodun OA, Gerber PF, Giménez-Lirola LG, Kwaga JKP, Opriessnig T, 2014. First report of hepatitis E virus circulation in domestic pigs in Nigeria. Am J Trop Med Hyg 91: 699704.

    • Search Google Scholar
    • Export Citation
  • 16.

    Tamura K, Stecher G, Peterson D, Filipski A, Kumar S, 2013. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol 30: 27252729.

    • Search Google Scholar
    • Export Citation
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Hepatitis E Virus Exposure is Increased in Pork Butchers from Burkina Faso

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  • LaBESTA/CRSBAN, EDST, Université de Ouagadougou, Ouagadougou, Burkina Faso; Service d'Immuno-Virologie, Institut des Maladies Emergentes et Thérapeutiques Innovantes, Commissariat à l'Energie Atomique (CEA), Inserm U1184, Center for Immunology of Viral Infections and Autoimmune Diseases, Fontenay-aux-Roses, France; Université Paris-Sud, Orsay, France; ANSES, UMR 1161 Virologie, INRA, ENVA, University Paris-Est, Maisons-Alfort, France
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We conducted the first survey of zoonotic risk of Hepatitis E virus (HEV) transmissions in Ouagadougou, Burkina Faso, through the direct contact with pork meat during professional activity. Anti-HEV antibodies were more prevalent in pork butchers, 76% than in the general population, which was 47.8% in 2013 (odds ratio = 3.46, 95% CI = 2.85–4.21, P < 0.001). Among slaughter-aged swine, HEV seroprevalence was of 80%, and HEV RNA was detected in 1% of pork livers. Phylogenetic analysis pointed out HEV genotype 3. Thus, in addition to possible HEV contamination through the water source, as in endemic region, zoonotic transmissions of HEV probably occur in west Africa.

Author Notes

* Address correspondence to Pierre Roques, Service d'Immuno-Virologie, iMETI, CEA, 18 Route du Panorama, 92265 Fontenay-aux-Roses, France. E-mail: pierre.roques@cea.fr

Financial support: This study was supported by the French Government through the 3rd cycle university scholarship program cooperation of the French Embassy in Burkina Faso (www.burkina.campusfrance.org) and a cotutelle thesis grant from the University Paris-Sud.

Authors' addresses: Kuan Abdoulaye Traoré, Jean Bienvenue Ouoba, Alfred S. Traoré, and Nicolas Barro, LaBesta/CRSBAN, EDST, Université de Ouagadougou, Ouagadougou, Burkina Faso, E-mails: kuabtraore@live.fr, maitreouob@gmail.com, astraore@univ-ouaga.bf, and barronicolas@yahoo.fr. Sophie Rogée, Marine Dumarest, and Nicole Pavio, ANSES, UMR1161 Virologie, Maisons-Alfort, France, E-mails: rogeeso@aol.com, marinedumarest@gmail.com, and nicole.pavio@anses.fr. Nicolas Huot and Pierre Roques, Service d'Immuno-Virologie, CEA, Fontenay-aux-Roses, France, E-mails: nicolas.huot2@cea.fr and pierre.roques@cea.fr.

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