ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Gubler DJ, Kuno G, Markoff L, 2007. Flaviviruses. Fields Virology, 5th edition. Knipe DM, Howley PM, eds. Philadelphia, PA: Walters Kluwer/Lippincott Williams and Wilkins, 1153–1252.
-
2.
Kuno G, 2004. A survey of the relationships among the viruses not considered arboviruses, vertebrates and arthropods. Acta Virol 48: 135–143.
-
3.
Kuno G, 2007. Host range specificity of flaviviruses: correlation with in vitro replication. J Med Entomol 44: 93–101.
-
4.
Stollar V, Thomas VL, 1975. An agent in the Aedes aegypti cell line (Peleg) which causes fusion of Aedes albopictus cells. Virology 64: 367–377.
-
5.
Igarashi A, Harrap KA, Casals J, Stollar V, 1976. Morphological, biochemical, and serological studies on a viral agent (CFA) which replicates in and causes fusion of Aedes albopictus (Singh) cells. Virology 74: 174–187.
-
6.
Cook S, Moureau G, Kitchen A, Could EA, de Lamballerie X, Holmes EC, Harbach RE, 2012. Molecular evolution of the insect-specific flaviviruses. J Gen Virol 93: 223–234.
-
7.
Juglen S, Drosten C, 2013. Virus discovery and recent insights into virus diversity in arthropods. Curr Opin Microbiol 16: 1–7.
-
8.
Hobson-Peters J, Yam AWY, Lu JWF, Seteh YX, May FJ, Kurucz N, Walsh S, Prow NA, Davis SS, Weir R, Melville L, Hunt N, Webb RI, Blitvich BJ, Whenlan P, Hall RA, 2013. A new insect-specific flavivirus from northern Australia suppresses replication of West Nile virus and Murray Valley encephalitis virus in co-infected mosquito cells. PLoS One 8: e56534.
-
9.
Haddow AD, Guzman H, Popov VL, Wood TG, Widen S, Tesh RB, Weaver SC, 2013. Isolation of Aedes flavivirus in the Western Hemisphere and evidence of vertical transmission in the mosquito Aedes (Stegomyia) albopictus (Diptera: Culicidae). Virology 440: 134–139.
-
10.
Carrera JP, Forrester N, Wang E, Vittor AY, Haddow AD, Lopez-Verges S, Abadia I, Castano E, Sosa N, Baez C, Estripeaut D, Diaz Y, Beltran D, Cisneros J, Cedeno HG, Travassos da Rosa AP, Hernandez H, Martinez-Torres AO, Tesh RB, Weaver SC, 2013. Eastern equine encephalitis in Latin America. N Engl J Med 369: 732–744.
-
11.
Holdridge LR, Dudowski G, 1956. Report on an ecological survey of the republic of Panama. Caribb Forest 17: 92–110.
-
12.
Service MW, 1993. Sampling adults with carbon dioxide traps, light traps, visual attraction traps and sound traps. Mosquito Ecology: Field Sampling Methods, 2nd edition. London, United Kingdom: Elsevier Applied Science, 499–610.
-
13.
Sallum MA, Forattini OP, 1996. Revision of the Spissipes Section of Culex (Melanoconion) (Diptera:Culicidae). J Am Mosq Control Assoc 12: 517–600.
-
14.
Vasilakis N, Forrester NL, Palacios G, Nasar F, Savji N, Rossi SL, Guzman H, Wood TG, Popov V, Gorchakov R, Gonzalez AV, Haddow AD, Watts DM, da Rosa AP, Weaver SC, Lipkin WI, Tesh RB, 2013. Negevirus: a proposed new taxon of insect-specific viruses with wide geographic distribution. J Virol 87: 2475–2488.
-
15.
Lohse M, Bolger AM, Nagel A, Fernie AR, Lunn JE, Stitt M, Usadel B, 2012. RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics. Nucleic Acids Res 40: W622–W627.
-
16.
Simpson JT, Wong K, Jackman SD, Schein JE, Jones SJ, Birol I, 2009. ABySS: a parallel assembler for short read sequence data. Genome Res 19: 1117–1123.
-
17.
Langmead B, Salzberg SL, 2012. Fast gapped-read alignment with Bowtie 2. Nat Methods 9: 357–359.
-
18.
Robinson JT, Thorvaldsdottir H, Winckler W, Guttman M, Lander ES, Getz G, Mesirov JP, 2011. Integrative genomics viewer. Nat Biotechnol 29: 24–26.
-
19.
Posada D, Crandall KA, 1998. MODELTEST: testing the model of DNA substitution. Bioinformatics 14: 817–818.
-
20.
Huelsenbeck JP, Ronquist F, 2001. MRBAYES: Bayesian inference of phylogeny. Bioinformatics 17: 754–755.
-
21.
Ronquist F, Huelsenbeck JP, 2003. MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19: 1572–1574.
-
22.
Wengler G, Wengler G, 1981. Terminal sequences of the genome and replicatioe-form RNA of the flavivirus West Nile virus: absence of poly (A) and possible role in RNA replication. Virology 113: 544–555.
-
23.
Cammisa-Parks H, Cisar LA, Kane A, Stollar V, 1992. The complete nucleotide sequence of cell fusing agent (CFA): homology between the nonstructural proteins encoded by CFA and the nonstructural proteins encoded by arthropod-borne flaviviruses. Virology 189: 511–524.
-
24.
Cook S, Moureau G, Harbach RE, Mukwaya L, Goodger K, Ssenfuka F, Gould E, Holmes EC, de Lamballerie X, 2009. Isolation of a novel species of flavivirus and a new strain of Culex flavivirus (Flaviviridae) from a natural mosquito population in Uganda. J Gen Virol 90: 2669–2678.
-
25.
Crabtree MB, Nga PT, Miller BR, 2009. Isolation and characterization of a new mosquito flavivirus, Quang Binh virus, from Vietnam. Arch Virol 154: 857–860.
-
26.
Hoshino K, Isawa H, Tsuda Y, Yano K, Sasaki T, Yuda M, Takasaki T, Kobayashi M, Sawabe K, 2007. Genetic characterization of a new insect flavivirus isolated from Culex pipiens mosquito in Japan. Virology 359: 405–414.
-
27.
Tyler S, Bolling BG, Blair CD, Brault AC, Pabbaraju K, Armijos MV, Clark DC, Calisher CH, Drebot MA, 2011. Distribution and phylogenetic comparisons of a novel mosquito flavivirus sequence present in Culex tarsalis mosquitoes from western Canada with viruses isolated in California and Colorado. Am J Trop Med Hyg 85: 162–168.
-
28.
Crabtree MB, Sang RC, Stollar V, Dunster LM, Miller BR, 2003. Genetic and phenotypic characterization of the newly described insect flavivirus, Kamiti River virus. Arch Virol 148: 1095–1118.
-
29.
Hoshino K, Isawa H, Tsuda Y, Sawabe K, Kobayashi M, 2009. Isolation and characterization of a new insect flavivirus from Aedes albopictus and Aedes flavopictus mosquitoes in Japan. Virology 39: 119–129.
-
30.
Evangelista J, Cruz C, Guevara C, Astete H, Carey C, Kochel TJ, Morrison AC, Williams M, Halsey ES, Forshey BM, 2013. Characterization of a novel flavivirus isolated from Culex (Melanoconion) ocossa mosquitoes from Iquitos, Peru. J Gen Virol 94: 1266–1272.
-
31.
Junglen S, Kopp A, Kurth A, Pauli G, Ellerbrok H, Leendertz FH, 2009. A new flavivirus and a new vector: characterization of a novel flavivirus isolated from Uranotaenia mosquitoes from a tropical rain forest. J Virol 83: 4462–4468.
-
32.
Wang Z, Guo J, Han Y, An S, 2014. Donggang virus, complete genome. NCBI reference sequence: NC016997.1, Nov. 1, 2014.
-
33.
Huhtamo E, Putkuri N, Kurkela S, Manni T, Vaheri A, Vapalahti O, Uzcategue NY, 2009. Characterization of a novel flavivirus from mosqutioes in northern Europe that is related to mosquito-borne flaviviruses of the tropics. J Virol 83: 9532–9540.
-
34.
Kolodziejek J, Pachler K, Bin H, Mendelson E, Shulman L, Orshan L, Nowotny N, 2013. Barkedji virus, a novel mosquito-borne flavivirus identified in Culex perexiguus mosquitoes, Israel, 2011. J Gen Virol 94: 2449–2457.
-
35.
Kenney J, Solberg OD, Langevin SA, Brault AC, 2014. Characterization of a novel insect-specific flavivirus from Brazil: potential for inhibition of infection of arthropod cells with medically important flaviviruses. J Gen Virol 95: 2796–2808.
-
36.
Lee JS, Grubaugh ND, Kondig JP, Turell MJ, Kim HC, Klein TA, O'Guinn ML, 2013. Isolation and genomic characterization of Chaoyang virus strain ROK 144 from Aedes vexans nipponii from the Republic of Korea. Virology 435: 220–224.
-
37.
Vazquez A, Sanchez-Seco MP, Palacios G, Mojero F, Reyes N, Ruiz S, Aranda C, Marques E, Escosa R, Moreno J, Figuerola J, Tenorio A, 2012. Novel flaviviruses detected in different species of mosquitoes in Spain. Vector Borne Zoonotic Dis 12: 223–229.
-
38.
Saiyasombat R, Bolling BG, Brault AC, Bartholomay LC, Blitvich BJ, 2011. Evidence of efficient transovarial transmission of Culex flavivirus by Culex pipiens (Diptera: Culicidae). J Med Entomol 48: 1031–1038.
-
39.
Bolling BG, Vasilakis N, Guzman H, Widen SG, Wood TG, Popov VL, Thangamani S, Tesh RB, 2015. Insect-specific viruses detected in laboratory mosquito colonies and their potential implications for experiments evaluating arbovirus vector competence. Am J Trop Med Hyg 92: 422–428.
-
40.
Bolling BG, Olea-Popelka FJ, Eisen L, Moore CG, Blair CD, 2012. Transmission dynamics of an insect-specific flavivirus in a naturally infected Culex pipiens laboratory colony and effects of co-infection on vector competence for West Nile virus. Virology 427: 90–97.
-
41.
Kent RJ, Crabtree MB, Miller BR, 2010. Transmission of West Nile virus by Culex quinquefasicatus stay infected with Culex flavivirus Izabal. PLoS Negl Trop Dis 4: e671.
-
42.
Blair CD, 2011. Mosquito RNAi is the major innate immune pathway controlling arbovirus infection and transmission. Future Microbiol 6: 265–277.
-
43.
Fraqkoudis R, Attarzadeh-Yazdi G, Nash AA, Fazakerley JF, Kohl A, 2009. Advances in dissecting mosquito innate immune responses to arbovirus infection. J Gen Virol 90: 2061–2072.
-
44.
Schnettler E, Sterken MG, Leung JY, Metz SW, Geertsema C, Goldbach RW, Valk JM, Kohl A, Khromykh AA, Pijlman GB, 2012. Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and mammalian cells. J Virol 86: 13486–13500.
-
45.
Frantiu FD, Zakir T, Walker T, Popovici J, Pyke AT, van den Hurk A, McGraw EA, O'Neill SL, 2014. Limited dengue virus replication in field-collected Aedes aegypti mosquitoes infected with Wolbachia. PLoS Negl Trop Dis 8: e2688.
-
46.
Bian G, Xu Y, Lu P, Xie Y, Xi Z, 2010. The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti. PLoS Pathog 6: e1000833.
-
47.
Hussain M, Lu G, Torres S, Edmonds JH, Kay BH, Khromykh AA, Asgari S, 2013. Effect of Wolbachia on replication of West Nile virus in a mosquito cell line and adult mosquitoes. J Virol 87: 851–858.
-
48.
Ramirez JL, Souza-Neto J, Torres Cosme R, Rovira J, Ortiz A, Pascale JM, Dimopoulos G, 2012. Reciprocal tripartite interactions between the Aedes aegypti midgut microbiota, innate immune system and dengue virus influences vector competence. PLoS Neglected Trop Dis 6: e1561.
-
49.
Jupatanakul N, Sim S, Dimopoulos G, 2014. The insect microbiome modulates vector competence for arboviruses. Viruses 6: 4294–4313.
-
50.
Weaver SC, Coffey LL, Nussenzveig R, Ortiz D, Smith D, 2014. Vector competence. Gillespie SH, Smith GL, Osbourn A, eds. Microbe-Vector Interactions in Vector-Borne Diseases. Cambridge, United Kingdom: Cambridge University Press, 139–180.
-
51.
Hardy JL, 1988. Susceptibility and resistance of vector mosquitoes. Monath TP, ed. The Arboviruses: Epidemiology and Ecology, Vol. 1. Boca Raton, FL: CRC Press, Inc., 87–126.
-
52.
Espinoza-Gomez F, Lopez-Lemus AU, Rodriguez-Sanchez IP, Martinez-Fierro ML, Newton-Sanchez DA, Chavez-Flores E, Delgado-Enciso I, 2011. Detection of sequences from a potentially novel strain of cell fusing agent virus in Mexican Stegomyia (Aedes) aegypti mosquitoes. Arch Virol 156: 1263–1267.
-
53.
Cook S, Bennett SN, Holmes EC, De Cheese R, Moureau G, de Lamballerie X, 2006. Isolation of a new strain of the flavivirus cell fusing agent virus in a natural mosquito population from Puerto Rico. J Gen Virol 87: 735–748.
-
54.
Yamanaka A, Thongrungkiat S, Ramasoota P, Konishi E, 2013. Genetic and evolutionary analysis of cell-fusing agent virus based on Thai strains isolated in 2008 and 2012. Infect Genet Evol 19: 188–194.
-
55.
Bolling BG, Weaver SC, Tesh RB, Vasilakis N, 2015. Insect-specific virus discovery: significance for the arbovirus community. Viruses 7: 4911–4928.
-
56.
Coffey LL, Page BL, Greninger AL, Herring BL, Russell RC, Doggert SL, Haniotis J, Wang C, Deng X, Delwart EL, 2014. Enhanced arbovirus surveillance with deep sequencing: identification of novel rhabdoviruses and bunyaviruses in Australian mosquitoes. Virology 448: 146–158.
-
57.
Cooks S, Chung BYW, Bass D, Moureau G, Tang S, McAlister E, Culverwell CL, Glucksman E, Wang H, Brown TDK, Gould EA, Habach RE, de Lamballerie X, Firth AE, 2013. Novel virus discovery and genome reconstruciton from field RNA samples reveals highly divergent viruses in dipteran hosts. PLoS One 8: e80720.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1 | 1 | 1 |
| Full Text Views | 330 | 138 | 5 |
| PDF Downloads | 128 | 56 | 4 |
Mercadeo Virus: A Novel Mosquito-Specific Flavivirus from Panama
Viruses in the genus Flavivirus (family Flaviviridae) include many arthropod-borne viruses of public health and veterinary importance. However, during the past two decades an explosion of novel insect-specific flaviviruses (ISFs), some closely related to vertebrate pathogens, have been discovered. Although many flavivirus pathogens of vertebrates have been isolated from naturally infected mosquitoes in Panama, ISFs have not previously been reported from the country. This report describes the isolation and characterization of a novel ISF, tentatively named Mercadeo virus (MECDV), obtained from Culex spp. mosquitoes collected in Panama. Two MECDV isolates were sequenced and cluster phylogenetically with cell-fusing agent virus (CFAV) and Nakiwogo virus (NAKV) to form a distinct lineage within the insect-specific group of flaviviruses.
Author Notes
Financial support: This work was supported in part by NIH contract HHSN272201000040I/HHSN27200004/D04 (RBT, HG, VP, NV), FID-09-103 from SENACYT-Panama (J-PC) and by Ministerio de Economia y Finanzas de Panama, project code: 9044.027 (LC-C).
Authors' addresses: Jean-Paul Carrera, Department of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama, and School of Medicine, Columbus University, Panama City, Panama, E-mail: jpcarrera@gorgas.gob.pa. Hilda Guzman, Vsevolod Popov, Scott C. Weaver, Nikos Vasilakis, and Robert B. Tesh, Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, TX, and Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, TX, E-mails: hguzman@utmb.edu, vpopov@utmb.edu, sweaver@utmb.edu, nivasila@utmb.edu, and rbtesh@utmb.edu. Davis Beltrán, Yamilka Díaz, and Sandra López-Vergès, Department of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama, E-mails: dbelt16@gmail.com, yamilkavirus@gmail.com, and lvsandral@gmail.com. Rolando Torres-Cosme and Lorenzo Cáceres-Carrera, Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama, E-mails: tcrolando@yahoo.es and cacereslorenzo@gmail.com. Steven G. Widen and Thomas G. Wood, Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, TX, E-mails: sgwiden@utmb.edu and tgwood@utmb.edu.