PerlmanJE, KazacosKR, ImperatoGH, DesaiRU, SchulmanSK, EdwardsJ, PontrelliLR, MachadoFS, TanowitzHB, SaffraNA, 2010. Baylisascaris procyonis neural larva migrans in an infant in New York City. J Neuroparasitol1: 5.
PerlmanJEKazacosKRImperatoGHDesaiRUSchulmanSKEdwardsJPontrelliLRMachadoFSTanowitzHBSaffraNA, 2010. Baylisascaris procyonis neural larva migrans in an infant in New York City. J Neuroparasitol1: 5.)| false
by Richard R. Kudo, D. Sc., Professor of Zoology, the University of Illinois, Urbana, Illinois. Seven hundred seventy eight pages with 336 illustrations. Third edition, Charles C. Thomas, Springfield, Illinois, 1946
Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, New York; Department of Pediatrics, Albert Einstein College of Medicine, New York City, New York; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, and Jacobi Medical Center, Bronx, New York; Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana; Virology Laboratory, University of Iowa Children's Hospital, Iowa City, Iowa
Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.
* Address correspondence to Herbert B. Tanowitz, Department of Pathology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461. E-mail: firstname.lastname@example.org
Financial support: This work was supported in part by NIH Grant AI-89716 (CG).