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Influenza A and Parvovirus B19 Seropositivity Rates in Gabonese Infants

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  • Medical Research Center (CERMEL), Lambaréné, Gabon; Institute for Tropical Medicine, University of Tübingen, Germany; Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; Center for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands

Clinical and epidemiological data from Central Africa on influenza A and parvovirus B19 infections are limited. We analyzed 162 blood samples of infants 3, 9, 15, and 30 months of age for IgG antibodies against both pathogens. Antibody responses were 0, 3.7%, 12.3%, and 20.4% against influenza A; and 1.2%, 2.5%, 3.1%, and 9.3% against parvovirus B19, respectively. Seropositivity rates were 89.5 (95% confidence interval [CI]: 59–120.1) and 38.2 (95% CI: 18.9–57.6)/1,000 person-years at risk for influenza A and parvovirus B19, respectively. Our data add to the understanding of the epidemiology of both conditions.

Author Notes

* Address correspondence to Martin P. Grobusch, Center for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Academic Medical Center, Meibergdreef 9, 1100 DD Amsterdam, PO Box 22660, University of Amsterdam, The Netherlands. E-mail: m.p.grobusch@amc.uva.nl

Disclosure: Registration of the Lambaréné IPTi trial: Registry's URL, http://clinicaltrials.gov; trial registration number NCT 00167843.

Authors' addresses: Julian Gabor, Meral Esen, and Peter G. Kremsner, Institute of Tropical Medicine, Infectious Diseases, Tuebingen, Germany, E-mails: julian.gabor@gmx.de, meral.esen@uni-tuebingen.de, and peter.kremsner@uni-tuebingen.de. Norbert G. Schwarz, BNI, Epidemiology, Hamburg, Germany, E-mail: schwarz@bnitm.de. Martin P. Grobusch, Academic Medical Center, University of Amsterdam, Infectious Diseases, Tropical Medicine and AIDS, Amsterdam, The Netherlands, E-mail: m.p.grobusch@amc.uva.nl.

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