Guzman MG, Halstead SB, Artsob H, Buchy P, Farrar J, Gubler DJ, Hunsperger E, Kroeger A, Margolis HS, Martinez E, Nathan MB, Pelegrino JL, Simmons C, Yoksan S, Peeling RW, 2010. Dengue: a continuing global threat. Nat Rev Microbiol 8: S7–S16.
Queyriaux B, Simon F, Grandadam M, Michel R, Tolou H, Boutin JP, 2008. Clinical burden of chikungunya virus infection. Lancet Infect Dis 8: 2–3.
Charrel RN, de Lamballerie X, Raoult D, 2007. Chikungunya outbreaks–the globalization of vectorborne diseases. N Engl J Med 356: 769–771.
Thonnon J, Spiegel A, Diallo M, Diallo A, Fontenille D, 1999. Chikungunya virus outbreak in Senegal in 1996 and 1997. Bull Soc Pathol Exot 92: 79–82.
Pastorino B, Muyembe-Tamfum JJ, Bessaud M, Tock F, Tolou H, Durand JP, Peyrefitte CN, 2004. Epidemic resurgence of chikungunya virus in Democratic Republic of the Congo: identification of a new central African strain. J Med Virol 74: 277–282.
Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M, 2007. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis 7: 319–327.
Gould LH, Osman MS, Farnon EC, Griffith KS, Godsey MS, Karch S, Mulenda B, El Kholy A, Grandesso F, de Radigues X, Brair ME, Briand S, El Tayeb el SM, Hayes EB, Zeller H, Perea W, 2008. An outbreak of yellow fever with concurrent chikungunya virus transmission in South Kordofan, Sudan, 2005. Trans R Soc Trop Med Hyg 102: 1247–1254.
Hertz JT, Munishi OM, Ooi EE, Howe S, Lim WY, Chow A, Morrissey AB, Bartlett JA, Onyango JJ, Maro VP, Kinabo GD, Saganda W, Gubler DJ, Crump JA, 2012. Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania. Am J Trop Med Hyg 86: 171–177.
Caron M, Paupy C, Grard G, Becquart P, Mombo I, Nso BB, Kassa F, Nkoghe D, Leroy EM, 2012. Recent introduction and rapid dissemination of chikungunya virus and dengue virus serotype 2 associated with human and mosquito coinfections in Gabon, central Africa. Clin Infect Dis 55: e45–e53.
Kelvin AA, 2011. Outbreak of Chikungunya in the Republic of Congo and the global picture. J Infect Dev Ctries 5: 441–444.
Sutherland LJ, Cash AA, Huang YJ, Sang RC, Malhotra I, Moormann AM, King CL, Weaver SC, King CH, LaBeaud AD, 2011. Serologic evidence of arboviral infections among humans in Kenya. Am J Trop Med Hyg 85: 158–161.
Kuniholm MH, Wolfe ND, Huang CY, Mpoudi-Ngole E, Tamoufe U, LeBreton M, Burke DS, Gubler DJ, 2006. Seroprevalence and distribution of Flaviviridae, Togaviridae, and Bunyaviridae arboviral infections in rural Cameroonian adults. Am J Trop Med Hyg 74: 1078–1083.
Mease LE, Coldren RL, Musila LA, Prosser T, Ogolla F, Ofula VO, Schoepp RJ, Rossi CA, Adungo N, 2011. Seroprevalence and distribution of arboviral infections among rural Kenyan adults: a cross-sectional study. Virol J 8: 371.
Pistone T, Ezzedine K, Boisvert M, Receveur MC, Schuffenecker I, Zeller H, Lafon ME, Fleury H, Malvy D, 2009. Cluster of chikungunya virus infection in travelers returning from Senegal, 2006. J Travel Med 16: 286–288.
Jentes ES, Robinson J, Johnson BW, Conde I, Sakouvougui Y, Iverson J, Beecher S, Bah MA, Diakite F, Coulibaly M, Bausch DG, Bryan J, 2010. Acute arboviral infections in Guinea, West Africa, 2006. Am J Trop Med Hyg 83: 388–394.
Ansumana R, Jacobsen KH, Leski TA, Covington AL, Bangura U, Hodges MH, Lin B, Bockarie AS, Lamin JM, Bockarie MJ, Stenger DA, 2013. Reemergence of chikungunya virus in Bo, Sierra Leone. Emerg Infect Dis 19: 1108–1110.
Baba M, Logue CH, Oderinde B, Abdulmaleek H, Williams J, Lewis J, Laws TR, Hewson R, Marcello A, D'Agaro P, 2013. Evidence of arbovirus co-infection in suspected febrile malaria and typhoid patients in Nigeria. J Infect Dev Ctries 7: 51–59.
Fievet N, Varani S, Ibitokou S, Briand V, Louis S, Perrin RX, Massougbogji A, Hosmalin A, Troye-Blomberg M, Deloron P, 2009. Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells. Malar J 8: 251.
Nahum A, Erhart A, Mayé A, Ahounou D, van Overmeir C, Menten J, van Loen H, Akogbeto M, Coosemans M, Massougbodji A, D'Alessandro U, 2010. Malaria incidence and prevalence among children living in a peri-urban area on the coast of Benin, West Africa: a longitudinal study. Am J Trop Med Hyg 83: 465–473.
Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F, Silvi G, Angelini P, Dottori M, Ciufolini MG, Majori GC, Cassone A, 2007. Infection with chikungunya virus in Italy: an outbreak in a temperate region. Lancet 370: 1840–1846.
Eisenhut M, Schwarz TF, Hegenscheid B, 1999. Seroprevalence of dengue, chikungunya and sindbis virus infections in German aid workers. Infection 27: 82–85.
Fritel X, Rollot O, Gerardin P, Gauzere BA, Bideault J, Lagarde L, Dhuime B, Orvain E, Cuillier F, Ramful D, Samperiz S, Jaffar-Bandjee MC, Michault A, Cotte L, Kaminski M, Fourmaintraux A, 2006. Chikungunya virus infection during pregnancy, Reunion, France. Emerg Infect Dis 16: 418–425.
Gérardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, Lenglet Y, Touret Y, Bouveret A, Grivard P, Le Roux K, Blanc S, Schuffenecker I, Couderc T, Arenzana-Seisdedos F, Lecuit M, Robillard PY, 2008. Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Reunion. PLoS Med 5: e60.
Ramful D, Carbonnier M, Pasquet M, Bouhmani B, Ghazouani J, Noormahomed T, Beullier G, Attali T, Samperiz S, Fourmaintraux A, Alessandri JL, 2007. Mother-to-child transmission of Chikungunya virus infection. Pediatr Infect Dis J 26: 811–815.
Dauby N, Goetghebuer T, Kollmann TR, Levy J, Marchant A, 2012. Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections. Lancet Infect Dis 12: 330–340.
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The aim of this study was to investigate the seroprevalence of antichikungunya virus (anti-CHIKV) antibodies in pregnant women living in an urban area of Benin (West Africa). Results were obtained by screening sera collected in 2006 and 2007 with enzyme-linked immunosorbent assay (ELISA) for anti-CHIKV immunoglobulin G (IgG) and IgM. Positive results were confirmed by indirect immunofluorescence test and microneutralization assay. We found that a large proportion (36.1%) of pregnant women living in Cotonou had specific IgG against CHIKV, indicating a high seroprevalence of the infection in urban southern Benin, whereas no active cases of CHIKV infection were detected.
Financial support: This work was partially supported by funding from the Regione Emilia-Romagna, Italian Ministry of Health Grant RF-2009-1539631 (to V.S.), and University of Bologna Grant RFO (to M.P.L. and S.V.).
Authors' addresses: Anastasia Bacci, Serena Marchi, and Giada Rossini, Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St. Orsola-Malpighi University Hospital, Bologna, Italy, E-mails: analulo@libero.it, serena.marchi25@gmail.com, and giada.rossini@unibo.it. Nadine Fievet and Jean-Philippe Chippaux, Centre d'étude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance (CERPAGE), Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Benin, Institut de Recherche pour le Développement, Unitès mixtes de recherche (UMR) 216, Mère et Enfant Face aux Infections Tropicales, Paris, France, and Pres Sorbonne Paris Cité, Université Paris Descartes, Faculté de Pharmacie, France, E-mails: fievet@ird.fr and jean-philippe.chippaux@ird.fr. Achille Massougbodji and Renè Xavier Perrin, Centre d'étude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance (CERPAGE), Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Benin, E-mails: achille.massougbodji@ird.fr and perrinrx@yahoo.fr. Vittorio Sambri, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy, and Unit of Microbiology, Area Vasta Romagna (AVR), Pievesestina, Cesena, Italy, E-mail: vittorio.sambri@unibo.it. Maria Paola Landini and Stefania Varani, Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St. Orsola-Malpighi University Hospital, Bologna, Italy, and Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy, E-mails: mariapaola.landini@unibo.it and stefania.varani@unibo.it.
Guzman MG, Halstead SB, Artsob H, Buchy P, Farrar J, Gubler DJ, Hunsperger E, Kroeger A, Margolis HS, Martinez E, Nathan MB, Pelegrino JL, Simmons C, Yoksan S, Peeling RW, 2010. Dengue: a continuing global threat. Nat Rev Microbiol 8: S7–S16.
Queyriaux B, Simon F, Grandadam M, Michel R, Tolou H, Boutin JP, 2008. Clinical burden of chikungunya virus infection. Lancet Infect Dis 8: 2–3.
Charrel RN, de Lamballerie X, Raoult D, 2007. Chikungunya outbreaks–the globalization of vectorborne diseases. N Engl J Med 356: 769–771.
Thonnon J, Spiegel A, Diallo M, Diallo A, Fontenille D, 1999. Chikungunya virus outbreak in Senegal in 1996 and 1997. Bull Soc Pathol Exot 92: 79–82.
Pastorino B, Muyembe-Tamfum JJ, Bessaud M, Tock F, Tolou H, Durand JP, Peyrefitte CN, 2004. Epidemic resurgence of chikungunya virus in Democratic Republic of the Congo: identification of a new central African strain. J Med Virol 74: 277–282.
Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M, 2007. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis 7: 319–327.
Gould LH, Osman MS, Farnon EC, Griffith KS, Godsey MS, Karch S, Mulenda B, El Kholy A, Grandesso F, de Radigues X, Brair ME, Briand S, El Tayeb el SM, Hayes EB, Zeller H, Perea W, 2008. An outbreak of yellow fever with concurrent chikungunya virus transmission in South Kordofan, Sudan, 2005. Trans R Soc Trop Med Hyg 102: 1247–1254.
Hertz JT, Munishi OM, Ooi EE, Howe S, Lim WY, Chow A, Morrissey AB, Bartlett JA, Onyango JJ, Maro VP, Kinabo GD, Saganda W, Gubler DJ, Crump JA, 2012. Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania. Am J Trop Med Hyg 86: 171–177.
Caron M, Paupy C, Grard G, Becquart P, Mombo I, Nso BB, Kassa F, Nkoghe D, Leroy EM, 2012. Recent introduction and rapid dissemination of chikungunya virus and dengue virus serotype 2 associated with human and mosquito coinfections in Gabon, central Africa. Clin Infect Dis 55: e45–e53.
Kelvin AA, 2011. Outbreak of Chikungunya in the Republic of Congo and the global picture. J Infect Dev Ctries 5: 441–444.
Sutherland LJ, Cash AA, Huang YJ, Sang RC, Malhotra I, Moormann AM, King CL, Weaver SC, King CH, LaBeaud AD, 2011. Serologic evidence of arboviral infections among humans in Kenya. Am J Trop Med Hyg 85: 158–161.
Kuniholm MH, Wolfe ND, Huang CY, Mpoudi-Ngole E, Tamoufe U, LeBreton M, Burke DS, Gubler DJ, 2006. Seroprevalence and distribution of Flaviviridae, Togaviridae, and Bunyaviridae arboviral infections in rural Cameroonian adults. Am J Trop Med Hyg 74: 1078–1083.
Mease LE, Coldren RL, Musila LA, Prosser T, Ogolla F, Ofula VO, Schoepp RJ, Rossi CA, Adungo N, 2011. Seroprevalence and distribution of arboviral infections among rural Kenyan adults: a cross-sectional study. Virol J 8: 371.
Pistone T, Ezzedine K, Boisvert M, Receveur MC, Schuffenecker I, Zeller H, Lafon ME, Fleury H, Malvy D, 2009. Cluster of chikungunya virus infection in travelers returning from Senegal, 2006. J Travel Med 16: 286–288.
Jentes ES, Robinson J, Johnson BW, Conde I, Sakouvougui Y, Iverson J, Beecher S, Bah MA, Diakite F, Coulibaly M, Bausch DG, Bryan J, 2010. Acute arboviral infections in Guinea, West Africa, 2006. Am J Trop Med Hyg 83: 388–394.
Ansumana R, Jacobsen KH, Leski TA, Covington AL, Bangura U, Hodges MH, Lin B, Bockarie AS, Lamin JM, Bockarie MJ, Stenger DA, 2013. Reemergence of chikungunya virus in Bo, Sierra Leone. Emerg Infect Dis 19: 1108–1110.
Baba M, Logue CH, Oderinde B, Abdulmaleek H, Williams J, Lewis J, Laws TR, Hewson R, Marcello A, D'Agaro P, 2013. Evidence of arbovirus co-infection in suspected febrile malaria and typhoid patients in Nigeria. J Infect Dev Ctries 7: 51–59.
Fievet N, Varani S, Ibitokou S, Briand V, Louis S, Perrin RX, Massougbogji A, Hosmalin A, Troye-Blomberg M, Deloron P, 2009. Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells. Malar J 8: 251.
Nahum A, Erhart A, Mayé A, Ahounou D, van Overmeir C, Menten J, van Loen H, Akogbeto M, Coosemans M, Massougbodji A, D'Alessandro U, 2010. Malaria incidence and prevalence among children living in a peri-urban area on the coast of Benin, West Africa: a longitudinal study. Am J Trop Med Hyg 83: 465–473.
Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F, Silvi G, Angelini P, Dottori M, Ciufolini MG, Majori GC, Cassone A, 2007. Infection with chikungunya virus in Italy: an outbreak in a temperate region. Lancet 370: 1840–1846.
Eisenhut M, Schwarz TF, Hegenscheid B, 1999. Seroprevalence of dengue, chikungunya and sindbis virus infections in German aid workers. Infection 27: 82–85.
Fritel X, Rollot O, Gerardin P, Gauzere BA, Bideault J, Lagarde L, Dhuime B, Orvain E, Cuillier F, Ramful D, Samperiz S, Jaffar-Bandjee MC, Michault A, Cotte L, Kaminski M, Fourmaintraux A, 2006. Chikungunya virus infection during pregnancy, Reunion, France. Emerg Infect Dis 16: 418–425.
Gérardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, Lenglet Y, Touret Y, Bouveret A, Grivard P, Le Roux K, Blanc S, Schuffenecker I, Couderc T, Arenzana-Seisdedos F, Lecuit M, Robillard PY, 2008. Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Reunion. PLoS Med 5: e60.
Ramful D, Carbonnier M, Pasquet M, Bouhmani B, Ghazouani J, Noormahomed T, Beullier G, Attali T, Samperiz S, Fourmaintraux A, Alessandri JL, 2007. Mother-to-child transmission of Chikungunya virus infection. Pediatr Infect Dis J 26: 811–815.
Dauby N, Goetghebuer T, Kollmann TR, Levy J, Marchant A, 2012. Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections. Lancet Infect Dis 12: 330–340.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 35 | 35 | 2 |
Full Text Views | 409 | 193 | 0 |
PDF Downloads | 103 | 49 | 0 |