• 1.

    Igonoh AK, 2015. My experience as an Ebola patient. Am J Trop Med Hyg 92: 221222.

  • 2.

    Lamontagne F, Clement C, Fletcher T, Jacob ST, Fischer WA, Fowler RA, 2014. Doing today's work superbly well—treating Ebola with current tools. N Engl J Med 371: 15651566.

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    • Export Citation
  • 3.

    Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, de Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse AW, Addo MM, Schmiedel S, 2014. A case of severe Ebola virus infection complicated by gram-negative septicemia. N Engl J Med 371: 23942401.

    • Search Google Scholar
    • Export Citation
  • 4.

    Marshall Lyon G, Mehta A, Varkey J, Brantly K, Plyler L, McElroy AK, Kraft CS, Towner JS, Spiropoulou C, Ströher U, Uyeki TM, Ribner BS, 2014. Clinical care of two patients with Ebola virus disease in the United States. N Engl J Med 371: 24022409.

    • Search Google Scholar
    • Export Citation
  • 5.

    Jacobs M, Beadswoth M, Schmid M, Turnbridge A, 2014. Provision of care for Ebola. Lancet 384: 21052106.

  • 6.

    Chertow DS, Kleine C, Edwards JK, Scaini R, Giuliani R, Sprecher A, 2014. Ebola virus disease in West Africa—clinical manifestations and management. N Engl J Med 371: 20542057.

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    • Export Citation
 
 
 
 

 

 
 

 

 

 

 

 

 

Ebola and Cholera

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  • 1 President, Brighton Foundation US. West Chester, PA. E-mail: davidnalin@aol.com
  • | 2 Freelance Researcher UK, London, United Kingdom. E-mail: bertzpoet@yahoo.com

Dear Sir:

The description of the clinical course of Ebola virus disease (EVD) provided by Igonoh1 is consistent with mounting evidence indicating that a significant proportion of Ebola mortality is attributable to diarrheal dehydration with severe electrolyte losses.26 It is likely that EVD mortality could be reduced below reported levels if therapy could be streamlined as it has been for treatment of cholera. Reports of severe hyponatremia and hypokalemia in EVD suggest that stool sodium and potassium losses may exceed those in the current World Health Organization (WHO) low-sodium oral rehydration solution (ORS). Analysis of EVD stool electrolyte content would help define optimal ORS salt formulations for EVD, but unfortunately have not been reported. Such data are needed to identify the optimal standard ORS composition for EVD treatment.

  • 1.

    Igonoh AK, 2015. My experience as an Ebola patient. Am J Trop Med Hyg 92: 221222.

  • 2.

    Lamontagne F, Clement C, Fletcher T, Jacob ST, Fischer WA, Fowler RA, 2014. Doing today's work superbly well—treating Ebola with current tools. N Engl J Med 371: 15651566.

    • Search Google Scholar
    • Export Citation
  • 3.

    Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, de Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse AW, Addo MM, Schmiedel S, 2014. A case of severe Ebola virus infection complicated by gram-negative septicemia. N Engl J Med 371: 23942401.

    • Search Google Scholar
    • Export Citation
  • 4.

    Marshall Lyon G, Mehta A, Varkey J, Brantly K, Plyler L, McElroy AK, Kraft CS, Towner JS, Spiropoulou C, Ströher U, Uyeki TM, Ribner BS, 2014. Clinical care of two patients with Ebola virus disease in the United States. N Engl J Med 371: 24022409.

    • Search Google Scholar
    • Export Citation
  • 5.

    Jacobs M, Beadswoth M, Schmid M, Turnbridge A, 2014. Provision of care for Ebola. Lancet 384: 21052106.

  • 6.

    Chertow DS, Kleine C, Edwards JK, Scaini R, Giuliani R, Sprecher A, 2014. Ebola virus disease in West Africa—clinical manifestations and management. N Engl J Med 371: 20542057.

    • Search Google Scholar
    • Export Citation
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