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An Autochthonous Case of Severe Plasmodium knowlesi Malaria in Thailand
A 58-year-old Thai man was infected with Plasmodium knowlesi in Chantaburi Province, eastern Thailand. In addition to pyrexia, the patient developed hypotension, renal failure, jaundice, and severe thrombocytopenia. The parasitemia at the time of admission was 16.67% or ∼503,400 parasites/μL. With artesunate treatment and supportive care, the patient recovered uneventfully. The occurrence of complicated knowlesi malaria in a low-endemic area underscores the risk of high morbidity from this simian malaria.
Author Notes
Financial support: This study was supported by a grant from the Thai Government Budget for Research Fiscal Year 2012 and the Thailand Research Fund (grant No. RSA5480008).
Authors' addresses: Surat Nakaviroj, Prapokklao Hospital, Internal Medicine, Mueng, Chantaburi, Thailand, E-mail: surat_md55@hotmail.com. Teerayot Kobasa, Division of Vector-Borne Diseases, Ministry of Public Health, Disease Control, Mueng, Nonthaburi, Thailand, E-mail: ktheerayot@gmail.com. Phairote Teeranaipong, Chaturong Putaporntip, and Somchai Jongwutiwes, Faculty of Medicine, Chulalongkorn University, Parasitology, Pathumwan, Bangkok, Thailand, E-mail: phairote1@gmail.com, p.chaturong@gmail.com, and jongwutiwes@gmail.com.