The Severe Fever with Thrombocytopenia Syndrome Bunyavirus (SFTSV) Antibody in a Highly Endemic Region from 2011 to 2013: A Comparative Serological Study

Chunyan Hu Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Chentao Guo Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Zhendong Yang Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Liyuan Wang Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Jiangong Hu Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Shuli Qin Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Ning Cui Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Wei Peng Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Kun Liu Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Wei Liu Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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Wuchun Cao Graduate School of Anhui Medical University, Hefei, Anhui, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China; The 154 Hospital, Xinyang, Henan, China; The Shangcheng People's Hospital, Xinyang, Henan, China

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A seropositive rate of 6.59% was determined in the highly endemic region for severe fever with thrombocytopenia syndrome. A significant correlation was observed between case incidence and seroprevalence on temporal and geographic levels. Seroprevalence was comparable in the last 3 years, indicating a stable and ongoing circulation of the infection.

Author Notes

* Address correspondence to Wei Liu, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dongdajie Street, Fengtai District, Beijing 100071, China, E-mail: lwbime@163.com or Wuchun Cao, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dongdajie Street, Fengtai District, Beijing 100071, China, E-mail: caowc@bmi.ac.cn
† These authors contributed equally.

Financial support: This work was supported by Natural Science Foundation of China Grants 81222037, 81290344, and 81130086, China Mega-Project for Infectious Diseases Grant 2013ZX10004-202, and Special Fund for Quarantine-Scientific Research in the Public Interest Grant 201310076.

Authors' addresses: Chunyan Hu, Jiangong Hu, Kun Liu, and Wuchun Cao, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China, E-mails: valenccia@sina.com, hujiangong110@126.com, liukun5959@qq.com, and caowc@bmi.ac.cn. Chentao Guo, Liyuan Wang, and Wei Liu, Graduate School of Anhui Medical University, Hefei, Anhui, China, and State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China, E-mails: gctedison@163.com, wangliyuan612@126.com, and lwbime@163.com. Zhendong Yang, Shuli Qin, and Ning Cui, The 154 Hospital, Xinyang, Henan, China, E-mails: yzd57906@sina.com, fanxuejuan2012@sohu.com, and cnblcc@sohu.com. Wei Peng, The Shangcheng People's Hospital, Xinyang, Henan, China, E-mail: 13569774958@163.com.

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