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Trypanosoma cruzi Meningoencephalitis in a Patient with Acquired Immunodeficiency Syndrome

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  • Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas; National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas

As a result of global migration, a significant number of people with Trypanosoma cruzi infection now live in the United States, Canada, many countries in Europe, and other non-endemic countries. Trypanosoma cruzi meningoencephalitis is a rare cause of ring-enhancing lesions in patients with acquired immunodeficiency syndrome (AIDS) that can closely mimic central nervous system (CNS) toxoplasmosis. We report a case of CNS Chagas reactivation in an AIDS patient successfully treated with benznidazole and antiretroviral therapy in the United States.

Author Notes

* Address correspondence to Kosuke Yasukawa, Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030. E-mail: kosukeyaz@gmail.com

Authors' addresses: Kosuke Yasukawa and Charlene A. Flash, Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, TX, E-mails: kosukeyaz@gmail.com and Charlene.Flash@bcm.edu. Shital M. Patel, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, E-mail: shitalp@bcm.edu. Charles E. Stager and Jerry C. Goodman, Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, E-mails: cstager@bcm.edu and jgoodman@bcm.edu. Laila Woc-Colburn, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, E-mail: woccolbu@bcm.edu.

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