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Recurrences of Visceral Leishmaniasis Caused by Leishmania siamensis after Treatment with Amphotericin B in a Seronegative Child

Seksit OsatakulDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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Mathirut MungthinDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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Suradej SiripattanapipongDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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Atitaya HitakarunDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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Rommanee KositnitikulDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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Tawee NaaglorDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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Saovanee LeelayoovaDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand

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We report the first case of visceral leishmaniasis caused by Leishmania siamensis in a seronegative child. She was treated with amphotericin B at 1 mg/kg/day for 3 weeks; however, recurrences occurred twice. The patient was cured after the administration of amphotericin B for 5 weeks and monthly prophylaxis for 6 months.

Author Notes

* Address correspondence to Saovanee Leelayoova, Department of Parasitology, Phramongkutklao College of Medicine, Ratchawithi Rd., Bangkok 10400, Thailand. E-mail: s_leelayoova@scientist.com

Financial support: This study was supported by Prince of Songkla University and Phramongkutklao College of Medicine.

Authors' addresses: Seksit Osatakul, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand, E-mail: seksit_o@psu.ac.th. Mathirut Mungthin, Suradej Siripattanapipong, Atitaya Hitakarun, Rommanee Kositnitikul, Tawee Naaglor, and Saovanee Leelayoova, Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand, E-mails: mathirut@pmk.ac.th, suradejs@rocketmail.com, aor_meddream@hotmail.com, kik_kuru@yahoo.com, Tawee_narkloar@hotmail.com, and s_leelayoova@scientist.com.

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