Coxiella burnetii in Rodents on Heixiazi Island at the Sino-Russian Border

Lijuan Liu Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Xu Baoliang Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Fu Yingqun Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Li Ming Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Yang Yu Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Hou Yong Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Wang Shasha Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Hu Manxia Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Guo Tianyu Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Jiang Chao Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Sun Xiaohong Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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Wang Jing Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

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This work is a molecular epidemiologic study to detect the incidence of Coxiella burnetii in rodents on Heixiazi Island at the Sino-Russian border of Heilongjiang Province. Liver tissues were extracted and processed to test the incidence of C. burnetii infection using polymerase chain reaction analysis. In total, 18% (66 of 370) of rodents tested positive for infection. The results of logistic regression analysis indicated that infection with C. burnetii was associated significantly with weight and month of capture, and infection was found in all rodent species that were observed; there was no significant difference of sex on the infection of C. burnetii. Though phylogenetic analysis disclosed heterogeneity in the nucleotide sequences isolated from the island rodents, the majority of observed strains were among the most common strains found worldwide. This is the first report on the incidence of C. burnetii in rodents on Heixiazi Island at the Sino-Russian border.

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Author Notes

* Address correspondence to Wang Jing, No. A 3, Gaobeidian North Road, Chaoyang District, Beijing 100123, China. E-mail: wangjing0115@126.com

Financial support: This study was supported by Basic Research Expenditure of CAIQ 2012JK038, and the National Special Project of International Cooperation in Science and Technology 2012DFA30540 and 2010DFA34250.

Disclosure: Dr. Liu is an epidemiologist at the Institute of Health Quarantine of CAIQ. Her primary research interest is public health in the field of Quarantine.

Authors' addresses: Lijuan Liu, Xu Baoliang, Guo Tianyu, Yang Yu, Sun Xiaohong, and Wang Jing, Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, PRC, E-mails: lljyhxx@126.com, xubaol@yahoo.com.cn, gty200411@sina.com, redyy99@gmail.com, dotsunny@hotmail.com, and wangjing0115@126.com. Fu Yingqun, Li Ming, and Hou Yong, Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, PRC, E-mails: fuyingqun109@yahoo.com.cn, chfi2002@163.com, lemon_hy2003@126.com. Jiang Chao and Wang Shasha, Department of Zoology, Shenyang Agriculture University, Shenyang, PRC, E-mails: jc_0043@163.com and wangsha_327@163.com. Hu Manxia, Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, PRC, E-mail: hmx1@163.com.

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