Coxiella burnetii in Rodents on Heixiazi Island at the Sino-Russian Border

Lijuan Liu Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Lijuan Liu in
Current site
Google Scholar
PubMed Close
,
Xu Baoliang Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Xu Baoliang in
Current site
Google Scholar
PubMed Close
,
Fu Yingqun Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Fu Yingqun in
Current site
Google Scholar
PubMed Close
,
Li Ming Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Li Ming in
Current site
Google Scholar
PubMed Close
,
Yang Yu Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Yang Yu in
Current site
Google Scholar
PubMed Close
,
Hou Yong Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Hou Yong in
Current site
Google Scholar
PubMed Close
,
Wang Shasha Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Wang Shasha in
Current site
Google Scholar
PubMed Close
,
Hu Manxia Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Hu Manxia in
Current site
Google Scholar
PubMed Close
,
Guo Tianyu Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Guo Tianyu in
Current site
Google Scholar
PubMed Close
,
Jiang Chao Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Jiang Chao in
Current site
Google Scholar
PubMed Close
,
Sun Xiaohong Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Sun Xiaohong in
Current site
Google Scholar
PubMed Close
, and
Wang Jing Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, People's Republic of China; Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, People's Republic of China; Department of Zoology, Shenyang Agriculture University, Shenyang, People's Republic of China; Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, People's Republic of China

Search for other papers by Wang Jing in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.12-0580
Volume/Issue:
Volume 88: Issue 4
Page(s):
770–773
Restricted access
Get Permissions

This work is a molecular epidemiologic study to detect the incidence of Coxiella burnetii in rodents on Heixiazi Island at the Sino-Russian border of Heilongjiang Province. Liver tissues were extracted and processed to test the incidence of C. burnetii infection using polymerase chain reaction analysis. In total, 18% (66 of 370) of rodents tested positive for infection. The results of logistic regression analysis indicated that infection with C. burnetii was associated significantly with weight and month of capture, and infection was found in all rodent species that were observed; there was no significant difference of sex on the infection of C. burnetii. Though phylogenetic analysis disclosed heterogeneity in the nucleotide sequences isolated from the island rodents, the majority of observed strains were among the most common strains found worldwide. This is the first report on the incidence of C. burnetii in rodents on Heixiazi Island at the Sino-Russian border.

    • Supplemental Materials (PDF 426 KB)

Author Notes

* Address correspondence to Wang Jing, No. A 3, Gaobeidian North Road, Chaoyang District, Beijing 100123, China. E-mail: wangjing0115@126.com

Financial support: This study was supported by Basic Research Expenditure of CAIQ 2012JK038, and the National Special Project of International Cooperation in Science and Technology 2012DFA30540 and 2010DFA34250.

Disclosure: Dr. Liu is an epidemiologist at the Institute of Health Quarantine of CAIQ. Her primary research interest is public health in the field of Quarantine.

Authors' addresses: Lijuan Liu, Xu Baoliang, Guo Tianyu, Yang Yu, Sun Xiaohong, and Wang Jing, Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, PRC, E-mails: lljyhxx@126.com, xubaol@yahoo.com.cn, gty200411@sina.com, redyy99@gmail.com, dotsunny@hotmail.com, and wangjing0115@126.com. Fu Yingqun, Li Ming, and Hou Yong, Department of Health and Quarantine, Heilongjiang Entry-Exit Inspection and Quarantine Bureau, Harbin, PRC, E-mails: fuyingqun109@yahoo.com.cn, chfi2002@163.com, lemon_hy2003@126.com. Jiang Chao and Wang Shasha, Department of Zoology, Shenyang Agriculture University, Shenyang, PRC, E-mails: jc_0043@163.com and wangsha_327@163.com. Hu Manxia, Department of Health and Quarantine, Suifenhe Entry-Exit Inspection and Quarantine Bureau, PRC, E-mail: hmx1@163.com.

Copyright:
© The American Society of Tropical Medicine and Hygiene 2013
Received:
16 Sep 2012
|
Accepted:
09 Jan 2013
|
Published Online:
03 Apr 2013
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Online ISSN:
1476-1645
  • 1.

    Parker NR, Barralet JH, Bell AM, 2006. Q fever. Lancet 367: 679–688.

  • 2.

    Raoult D, Marrie T, Mege J, 2005. Natural history and pathophysiology of Q fever. Lancet Infect Dis 5: 219–226.

  • 3.

    Andoh M, Naganawa T, Hotta A, Yamaguchi T, Fukushi H, Masegi T, Hirai K, 2003. SCID mouse model for lethal Q fever. Infect Immun 71: 4717–4723.

  • 4.

    Masala G, Porcu R, Sanna G, Chessa G, Cillara G, Chisu V, Tola S, 2004. Occurrence, distribution, and role in abortion of Coxiella burnetii in sheep and goats in Sardinia, Italy. Vet Microbiol 99: 301–305.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Madariaga MG, Rezai K, Trenholme GM, Weinstein RA, 2003. Q fever: a biological weapon in your backyard. Lancet Infect Dis 3: 709–721.

  • 6.

    Potasman I, Rzotkiewicz S, Pick N, Keysary A, 2000. Outbreak of Q fever following a safari trip. Clin Infect Dis 30: 215–217.

  • 7.

    Jiang JF, Zuo SQ, Zhang WY, Wu XM, Tang F, De Vlas SJ, Zhao WJ, Zhang PH, Dun Z, Wang RM, Cao WC, 2008. Prevalence and genetic diversities of hantaviruses in rodents in Beijing, China. Am J Trop Med Hyg 78: 98–105.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Akihiko HI, Akiko NA, Takashi CH, Akemi KA, 2012. Development of a method for detecting Coxiella burnetii in cheese samples. J Vet Med Sci 74: 175–180.

  • 9.

    McCaughey C, Murray LJ, McKenna LP, Menzies FD, McCullough SJ, O'Neill HJ, Wyatt DE, Cardwell CR, Coyle PV, 2009. Coxiella burnetii (Q fever) seroprevalence in cattle. Epidemiol Infect 138: 21–27.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Tilburg JJ, Roest H-J, Buffet S, Nabuurs-Franssen MH, Horrevorts AM, Raoult D, Klaassen CH, 2012. Epidemic genotype of Coxiella burnetii among goats, sheep, and humans in the Netherlands. Emerg Infect Dis 18: 887–889.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    Rodolakis A, 2006. Q fever, state of the art: epidemiology, diagnosis and prophylaxis. Small Rumin Res 62: 121–124.

  • 12.

    Mediannikov O, Fenollar F, Socolovschi C, Diatta G, Bassene H, Molez JF, Sokhna C, Trape JF, Raoult D, 2010. Coxiella burnetii in humans and ticks in rural Senegal. PLoS Negl Trop Dis 4: e654.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13.

    Reusken C, van der Plaats R, Opsteegh M, de Bruin A, Swart A, 2011. Coxiella burnetii (Q fever) in Rattus norvegicus and Rattus rattus at livestock farms and urban locations in the Netherlands; could Rattus spp. represent reservoirs for (re)introduction? Pre Vet Med 101: 124–130.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14.

    Riemann HP, Behymer DE, Franti CE, Crabb C, Schwab RG, 1979. Survey of Q-fever agglutinins in birds and small rodents in northern California, 1975–76. J Wildl Dis 15: 515–523.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15.

    Webster JP, Lloyd G, Macdonald DW, 1995. Q fever (Coxiella burnetii) reservoir in wild brown rat (Rattus norvegicus) populations in the UK. Parasitology 110: 31–35.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    Textoris J, Ban LH, Capo C, Raoult D, Leone M, Mege JL, 2010. Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm. PLoS ONE 5: e12190.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17.

    Plyusnin A, Morzunov SP, 2001. Virus evolution and genetic diversity of Hantaviruses and their rodent hosts. Curr Top Microbiol Immunol 256: 47–75.

Past two years Past Year Past 30 Days
Abstract Views 1154 934 223
Full Text Views 350 9 0
PDF Downloads 103 10 0
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save