ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
World Health Organization, 2012. Schistosomiasis, Fact Sheet No. 115. Geneva: World Health Organization.
-
2.
Gryseels B, Polman K, Clerinx J, Kestens L, 2006. Human schistosomiasis. Lancet 368: 1106–1118.
-
3.
Downs JA, Mguta C, Kaatano GM, Mitchell KB, Bang H, Simplice H, Kalluvya SE, Changalucha JM, Johnson WD Jr, Fitzgerald DW, 2011. Urogenital schistosomiasis in women of reproductive age in Tanzania's Lake Victoria region. Am J Trop Med Hyg 84: 364–369.
-
4.
Chenine AL, Shai-Kobiler E, Steele LN, Ong H, Augostini P, Song R, Lee SJ, Autissier P, Ruprecht RM, Secor WE, 2008. Acute Schistosoma mansoni infection increases susceptibility to systemic SHIV clade C infection in rhesus macaques after mucosal virus exposure. PLoS Negl Trop Dis 2: e265.
-
5.
Brown M, Mawa PA, Joseph S, Bukusuba J, Watera C, Whitworth JA, Dunne DW, Elliott AM, 2005. Treatment of Schistosoma mansoni infection increases helminth-specific type 2 cytokine responses and HIV-1 loads in coinfected Ugandan adults. J Infect Dis 191: 1648–1657.
-
6.
Elliott AM, Mawa PA, Joseph S, Namujju PB, Kizza M, Nakiyingi JS, Watera C, Dunne DW, Whitworth JA, 2003. Associations between helminth infection and CD4+ T cell count, viral load and cytokine responses in HIV-1-infected Ugandan adults. Trans R Soc Trop Med Hyg 97: 103–108.
-
7.
Fontanet AL, Woldemichael T, Sahlu T, van Dam GJ, Messele T, Rinke de Wit T, Masho W, Yeneneh H, Coutinho RA, van Lieshout L, 2000. Epidemiology of HIV and Schistosoma mansoni infections among sugar-estate residents in Ethiopia. Ann Trop Med Parasitol 94: 145–155.
-
8.
Ganley-Leal LM, Mwinzi PN, Cetre-Sossah CB, Andove J, Hightower AW, Karanja DM, Colley DG, Secor WE, 2006. Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans. Infect Immun 74: 2169–2176.
-
9.
Kallestrup P, Zinyama R, Gomo E, Butterworth AE, van Dam GJ, Erikstrup C, Ullum H, 2005. Schistosomiasis and HIV-1 infection in rural Zimbabwe: implications of coinfection for excretion of eggs. J Infect Dis 191: 1311–1320.
-
10.
Karanja DM, Colley DG, Nahlen BL, Ouma JH, Secor WE, 1997. Studies on schistosomiasis in western Kenya: I. evidence for immune-facilitated excretion of schistosome eggs from patients with Schistosoma mansoni and human immunodeficiency virus coinfections. Am J Trop Med Hyg 56: 515–521.
-
11.
Leutscher PD, van Dam GT, Reimert CM, Ramarakoto CE, Deelder AM, Ornbjerg N, 2008. Eosinophil cationic protein, soluble egg antigen, circulating anodic antigen, and egg excretion in male urogenital schistosomiasis. Am J Trop Med Hyg 79: 422–426.
-
12.
Corstjens PL, van Lieshout L, Zuiderwijk M, Kornelis D, Tanke HJ, Deelder AM, van Dam GJ, 2008. Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum. J Clin Microbiol 46: 171–176.
-
13.
Polman K, Diakhate MM, Engels D, Nahimana S, Van Dam GJ, Falcao Ferreira ST, Deelder AM, Gryseels B, 2000. Specificity of circulating antigen detection for schistosomiasis mansoni in Senegal and Burundi. Trop Med Int Health 5: 534–537.
-
14.
de Water R, Fransen JA, Deelder AM, 1986. Ultrastructural localization of the circulating anodic antigen in the digestive tract of Schistosoma mansoni using monoclonal antibodies in an immunogold labeling procedure. Am J Trop Med Hyg 35: 549–558.
-
15.
World Health Organization, 2006. Report of the Scientific Working Group Meeting on Schistosomiasis. Geneva: World Health Organization.
-
16.
World Health Organization, 2010. Report of an Informal Working Group on Urogenital Schistosomiasis and HIV Transmission. Geneva: World Health Organization.
-
17.
Clements AC, Lwambo NJ, Blair L, Nyandindi U, Kaatano G, Kinung'hi S, Webster JP, Fenwick A, Brooker S, 2006. Bayesian spatial analysis and disease mapping: tools to enhance planning and implementation of a schistosomiasis control programme in Tanzania. Trop Med Int Health 11: 490–503.
-
18.
Lwambo NJ, Siza JE, Brooker S, Bundy DA, Guyatt H, 1999. Patterns of concurrent hookworm infection and schistosomiasis in schoolchildren in Tanzania. Trans R Soc Trop Med Hyg 93: 497–502.
-
19.
Malenganisho WL, Magnussen P, Friis H, Siza J, Kaatano G, Temu M, Vennervald BJ, 2008. Schistosoma mansoni morbidity among adults in two villages along Lake Victoria shores in Mwanza district, Tanzania. Trans R Soc Trop Med Hyg 102: 532–541.
-
20.
van Dam GJ, Wichers JH, Ferreira TM, Ghati D, van Amerongen A, Deelder AM, 2004. Diagnosis of schistosomiasis by reagent strip test for detection of circulating cathodic antigen. J Clin Microbiol 42: 5458–5461.
-
21.
Wambura M, Urassa M, Isingo R, Ndege M, Marston M, Slaymaker E, Mngara J, Changalucha J, Boerma TJ, Zaba B, 2007. HIV prevalence and incidence in rural Tanzania: results from 10 years of follow-up in an open-cohort study. J Acquir Immune Defic Syndr 46: 616–623.
-
22.
Amsel R, Totten PA, Spiegel CA, Chen KC, Eschenbach D, Holmes KK, 1983. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 74: 14–22.
-
23.
De Jonge N, Gryseels B, Hilberath GW, Polderman AM, Deelder AM, 1988. Detection of circulating anodic antigen by ELISA for seroepidemiology of schistosomiasis mansoni. Trans R Soc Trop Med Hyg 82: 591–594.
-
24.
de Jonge N, De Caluwe P, Hilberath GW, Krijger FW, Polderman AM, Deelder AM, 1989. Circulating anodic antigen levels in serum before and after chemotherapy with praziquantel in schistosomiasis mansoni. Trans R Soc Trop Med Hyg 83: 368–372.
-
25.
Polman K, de Vlas SJ, Gryseels B, Deelder AM, 2000. Relating serum circulating anodic antigens to faecal egg counts in Schistosoma mansoni infections: a modelling approach. Parasitology 121: 601–610.
-
26.
Jonckheere AR, 1954. A distribution-free k-sample test against ordered alternatives. Biometrika 41: 133–145.
-
27.
Siddappa NB, Hemashettar G, Shanmuganathan V, Semenya AA, Sweeney ED, Paul KS, Lee SJ, Secor WE, Ruprecht RM, 2011. Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 clade C SHIV. PLoS Negl Trop Dis 5: e1270.
-
28.
Shainheit MG, Smith PM, Bazzone LE, Wang AC, Rutitzky LI, Stadecker MJ, 2008. Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology. J Immunol 181: 8559–8567.
-
29.
Rutitzky LI, Bazzone L, Shainheit MG, Joyce-Shaikh B, Cua DJ, Stadecker MJ, 2008. IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17. J Immunol 180: 2486–2495.
-
30.
Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, Scheinberg P, Price DA, Hage CA, Kholi LM, Khoruts A, Frank I, Else J, Schacker T, Silvestri G, Douek DC, 2008. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112: 2826–2835.
-
31.
McKinnon LR, Nyanga B, Chege D, Izulla P, Kimani M, Huibner S, Gelmon L, Block KE, Cicala C, Anzala AO, Arthos J, Kimani J, Kaul R, 2011. Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility. J Immunol 187: 6032–6042.
-
32.
Stabinski L, Reynolds SJ, Ocama P, Laeyendecker O, Ndyanabo A, Kiggundu V, Boaz I, Gray RH, Wawer M, Thio C, Thomas DL, Quinn TC, Kirk GD, Rakai Health Sciences Program, 2011. High prevalence of liver fibrosis associated with HIV infection: a study in rural Rakai, Uganda. Antivir Ther 16: 405–411.
-
33.
Secor WE, 2012. The effects of schistosomiasis on HIV/AIDS infection, progression and transmission. Curr Opin HIV AIDS 7: 254–259.
-
34.
Secor WE, Shah A, Mwinzi PM, Ndenga BA, Watta CO, Karanja DM, 2003. Increased density of human immunodeficiency virus type 1 coreceptors CCR5 and CXCR4 on the surfaces of CD4(+) T cells and monocytes of patients with Schistosoma mansoni infection. Infect Immun 71: 6668–6671.
-
35.
Kallestrup P, Zinyama R, Gomo E, Butterworth AE, Mudenge B, van Dam GJ, Gerstoft J, Erikstrup C, Ullum H, 2005. Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA load. J Infect Dis 192: 1956–1961.
-
36.
Lawn SD, Karanja DM, Mwinzia P, Andove J, Colley DG, Folks TM, Secor WE, 2000. The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals. AIDS 14: 2437–2443.
-
37.
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH, 2005. Treatment of intestinal helminths does not reduce plasma concentrations of HIV-1 RNA in coinfected Zambian adults. J Infect Dis 192: 1277–1283.
-
38.
Secor WE, 2005. Immunology of human schistosomiasis: off the beaten path. Parasite Immunol 27: 309–316.
-
39.
Todd J, Grosskurth H, Changalucha J, Obasi A, Mosha F, Balira R, Orroth K, Hugonnet S, Pujades M, Ross D, Gavyole A, Mabey D, Hayes R, 2006. Risk factors influencing HIV infection incidence in a rural African population: a nested case-control study. J Infect Dis 193: 458–466.
-
40.
van Dam GJ, Bogitsh BJ, van Zeyl RJ, Rotmans JP, Deelder AM, 1996. Schistosoma mansoni: in vitro and in vivo excretion of CAA and CCA by developing schistosomula and adult worms. J Parasitol 82: 557–564.
-
41.
Kremsner PG, Enyong P, Krijger FW, De Jonge N, Zotter GM, Thalhammer F, Muhlschlegel F, Bienzle U, Feldmeier H, Deelder AM, 1994. Circulating anodic and cathodic antigen in serum and urine from Schistosoma haematobium-infected cameroonian children receiving praziquantel: a longitudinal study. Clin Infect Dis 18: 408–413.
-
42.
van Lieshout L, Polderman AM, Deelder AM, 2000. Immunodiagnosis of schistosomiasis by determination of the circulating antigens CAA and CCA, in particular in individuals with recent or light infections. Acta Trop 77: 69–80.
-
43.
Karanja DM, Hightower AW, Colley DG, Mwinzi PN, Galil K, Andove J, Secor WE, 2002. Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility to schistosomiasis: a longitudinal study. Lancet 360: 592–596.
-
44.
Trushin P, Bang H, 2010. The role of epidemiology and biostatistics in health news reporting. Finkel M, ed. Public Health in the 21st Century. Santa Barbara, CA: ABC-CLIO, LLC.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 877 | 807 | 273 |
| Full Text Views | 729 | 19 | 1 |
| PDF Downloads | 240 | 9 | 0 |
Association of Schistosomiasis and HIV Infection in Tanzania
Jennifer A. Downs
Jennifer A. Downs
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Jennifer A. Downs in
Current site
Google Scholar
PubMed
Search for other papers by Jennifer A. Downs in
Current site
Google Scholar
PubMed
Govert J. van Dam
Govert J. van Dam
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Govert J. van Dam in
Current site
Google Scholar
PubMed
Search for other papers by Govert J. van Dam in
Current site
Google Scholar
PubMed
John M. Changalucha
John M. Changalucha
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by John M. Changalucha in
Current site
Google Scholar
PubMed
Search for other papers by John M. Changalucha in
Current site
Google Scholar
PubMed
Paul L. A. M. Corstjens
Paul L. A. M. Corstjens
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Paul L. A. M. Corstjens in
Current site
Google Scholar
PubMed
Search for other papers by Paul L. A. M. Corstjens in
Current site
Google Scholar
PubMed
Robert N. Peck
Robert N. Peck
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Robert N. Peck in
Current site
Google Scholar
PubMed
Search for other papers by Robert N. Peck in
Current site
Google Scholar
PubMed
Claudia J. de Dood
Claudia J. de Dood
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Claudia J. de Dood in
Current site
Google Scholar
PubMed
Search for other papers by Claudia J. de Dood in
Current site
Google Scholar
PubMed
Heejung Bang
Heejung Bang
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Heejung Bang in
Current site
Google Scholar
PubMed
Search for other papers by Heejung Bang in
Current site
Google Scholar
PubMed
Aura Andreasen
Aura Andreasen
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Aura Andreasen in
Current site
Google Scholar
PubMed
Search for other papers by Aura Andreasen in
Current site
Google Scholar
PubMed
Samuel E. Kalluvya
Samuel E. Kalluvya
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Samuel E. Kalluvya in
Current site
Google Scholar
PubMed
Search for other papers by Samuel E. Kalluvya in
Current site
Google Scholar
PubMed
Lisette van Lieshout
Lisette van Lieshout
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Lisette van Lieshout in
Current site
Google Scholar
PubMed
Search for other papers by Lisette van Lieshout in
Current site
Google Scholar
PubMed
Warren D. Johnson Jr.
Warren D. Johnson Jr.
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Warren D. Johnson Jr. in
Current site
Google Scholar
PubMed
Search for other papers by Warren D. Johnson Jr. in
Current site
Google Scholar
PubMed
Daniel W. Fitzgerald
Daniel W. Fitzgerald
Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands; National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, California; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
Search for other papers by Daniel W. Fitzgerald in
Current site
Google Scholar
PubMed
Search for other papers by Daniel W. Fitzgerald in
Current site
Google Scholar
PubMed
Animal and human studies suggest that Schistosoma mansoni infection may increase risk of human immunodeficiency virus (HIV) acquisition. Therefore, we tested 345 reproductive age women in rural Tanzanian villages near Lake Victoria, where S. mansoni is hyperendemic, for sexually transmitted infections (STIs) and schistosomiasis by circulating anodic antigen (CAA) serum assay. Over one-half (54%) had an active schistosome infection; 6% were HIV-seropositive. By univariate analysis, only schistosome infection predicted HIV infection (odds ratio [OR] = 3.9, 95% confidence interval = [1.3–12.0], P = 0.015) and remained significant using multivariate analysis to control for age, STIs, and distance from the lake (OR = 6.2 [1.7–22.9], P = 0.006). HIV prevalence was higher among women with more intense schistosome infections (P = 0.005), and the median schistosome intensity was higher in HIV-infected than -uninfected women (400 versus 15 pg CAA/mL, P = 0.01). This finding suggests that S. mansoni infection may be a modifiable HIV risk factor that places millions of people worldwide at increased risk of HIV acquisition.
Author Notes
Financial support: This work was supported by the 2009 Merle A. Sande/Pfizer Fellowship Award in International Infectious Diseases, which is awarded annually by the Infectious Diseases Society of America Education & Research Foundation and the National Foundation for Infectious Diseases. This work was also supported by Agency for Healthcare Research and Quality Grant T32HS000066, National Institute for Allergy and Infectious Diseases Grant T32AI007613, and Clinical and Translational Science Center at Weill Cornell Medical College Grant UL1-RR024996 (to J.A.D.). Various improvements of the upconverting phosphor-LF assay for circulating anodic antigen detection, involving the implementation of dry reagents (allowing worldwide shipping), increased sensitivity, and handheld upconverting phosphor readers, were developed, in part, with financial support from US National Institutes of Health Grant UO1DE017855 and the University of Georgia Research Foundation, Inc. (Schistosomiasis Consortium for Operational Research and Evaluation [SCORE] project).
Authors' addresses: Jennifer A. Downs, Robert N. Peck, Warren D. Johnson Jr., and Daniel W. Fitzgerald, Center for Global Health, Weill Cornell Medical College, New York, NY, E-mails: jna2002@med.cornell.edu, rnp2002@med.cornell.edu, wdjohnso@med.cornell.edu, and dfitzgerald@gheskio.org. Govert J. van Dam and Lisette van Lieshout, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands, E-mails: G.J.van_Dam@lumc.nl and E.A.van_Lieshout@lumc.nl. John M. Changalucha, National Institute for Medical Research, Mwanza Research Centre, Mwanza, Tanzania, E-mail: jchangalucha@yahoo.com. Paul L. A. M. Corstjens and Claudia J. de Dood, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands, E-mails: P.Corstjens@lumc.nl and C.J.de_Dood@lumc.nl. Heejung Bang, Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, CA, E-mail: hbang@phs.ucdavis.edu. Aura Andreasen, Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom; and Mwanza Interventional Trials Unit, Mwanza, Tanzania, E-mail: aura.andreasen@mitu.or.tz. Samuel E. Kalluvya, Department of Internal Medicine, Bugando Medical Centre, Mwanza, Tanzania, E-mail: samuelkalluvya@yahoo.com.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
World Health Organization, 2012. Schistosomiasis, Fact Sheet No. 115. Geneva: World Health Organization.
-
2.
Gryseels B, Polman K, Clerinx J, Kestens L, 2006. Human schistosomiasis. Lancet 368: 1106–1118.
-
3.
Downs JA, Mguta C, Kaatano GM, Mitchell KB, Bang H, Simplice H, Kalluvya SE, Changalucha JM, Johnson WD Jr, Fitzgerald DW, 2011. Urogenital schistosomiasis in women of reproductive age in Tanzania's Lake Victoria region. Am J Trop Med Hyg 84: 364–369.
-
4.
Chenine AL, Shai-Kobiler E, Steele LN, Ong H, Augostini P, Song R, Lee SJ, Autissier P, Ruprecht RM, Secor WE, 2008. Acute Schistosoma mansoni infection increases susceptibility to systemic SHIV clade C infection in rhesus macaques after mucosal virus exposure. PLoS Negl Trop Dis 2: e265.
-
5.
Brown M, Mawa PA, Joseph S, Bukusuba J, Watera C, Whitworth JA, Dunne DW, Elliott AM, 2005. Treatment of Schistosoma mansoni infection increases helminth-specific type 2 cytokine responses and HIV-1 loads in coinfected Ugandan adults. J Infect Dis 191: 1648–1657.
-
6.
Elliott AM, Mawa PA, Joseph S, Namujju PB, Kizza M, Nakiyingi JS, Watera C, Dunne DW, Whitworth JA, 2003. Associations between helminth infection and CD4+ T cell count, viral load and cytokine responses in HIV-1-infected Ugandan adults. Trans R Soc Trop Med Hyg 97: 103–108.
-
7.
Fontanet AL, Woldemichael T, Sahlu T, van Dam GJ, Messele T, Rinke de Wit T, Masho W, Yeneneh H, Coutinho RA, van Lieshout L, 2000. Epidemiology of HIV and Schistosoma mansoni infections among sugar-estate residents in Ethiopia. Ann Trop Med Parasitol 94: 145–155.
-
8.
Ganley-Leal LM, Mwinzi PN, Cetre-Sossah CB, Andove J, Hightower AW, Karanja DM, Colley DG, Secor WE, 2006. Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans. Infect Immun 74: 2169–2176.
-
9.
Kallestrup P, Zinyama R, Gomo E, Butterworth AE, van Dam GJ, Erikstrup C, Ullum H, 2005. Schistosomiasis and HIV-1 infection in rural Zimbabwe: implications of coinfection for excretion of eggs. J Infect Dis 191: 1311–1320.
-
10.
Karanja DM, Colley DG, Nahlen BL, Ouma JH, Secor WE, 1997. Studies on schistosomiasis in western Kenya: I. evidence for immune-facilitated excretion of schistosome eggs from patients with Schistosoma mansoni and human immunodeficiency virus coinfections. Am J Trop Med Hyg 56: 515–521.
-
11.
Leutscher PD, van Dam GT, Reimert CM, Ramarakoto CE, Deelder AM, Ornbjerg N, 2008. Eosinophil cationic protein, soluble egg antigen, circulating anodic antigen, and egg excretion in male urogenital schistosomiasis. Am J Trop Med Hyg 79: 422–426.
-
12.
Corstjens PL, van Lieshout L, Zuiderwijk M, Kornelis D, Tanke HJ, Deelder AM, van Dam GJ, 2008. Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum. J Clin Microbiol 46: 171–176.
-
13.
Polman K, Diakhate MM, Engels D, Nahimana S, Van Dam GJ, Falcao Ferreira ST, Deelder AM, Gryseels B, 2000. Specificity of circulating antigen detection for schistosomiasis mansoni in Senegal and Burundi. Trop Med Int Health 5: 534–537.
-
14.
de Water R, Fransen JA, Deelder AM, 1986. Ultrastructural localization of the circulating anodic antigen in the digestive tract of Schistosoma mansoni using monoclonal antibodies in an immunogold labeling procedure. Am J Trop Med Hyg 35: 549–558.
-
15.
World Health Organization, 2006. Report of the Scientific Working Group Meeting on Schistosomiasis. Geneva: World Health Organization.
-
16.
World Health Organization, 2010. Report of an Informal Working Group on Urogenital Schistosomiasis and HIV Transmission. Geneva: World Health Organization.
-
17.
Clements AC, Lwambo NJ, Blair L, Nyandindi U, Kaatano G, Kinung'hi S, Webster JP, Fenwick A, Brooker S, 2006. Bayesian spatial analysis and disease mapping: tools to enhance planning and implementation of a schistosomiasis control programme in Tanzania. Trop Med Int Health 11: 490–503.
-
18.
Lwambo NJ, Siza JE, Brooker S, Bundy DA, Guyatt H, 1999. Patterns of concurrent hookworm infection and schistosomiasis in schoolchildren in Tanzania. Trans R Soc Trop Med Hyg 93: 497–502.
-
19.
Malenganisho WL, Magnussen P, Friis H, Siza J, Kaatano G, Temu M, Vennervald BJ, 2008. Schistosoma mansoni morbidity among adults in two villages along Lake Victoria shores in Mwanza district, Tanzania. Trans R Soc Trop Med Hyg 102: 532–541.
-
20.
van Dam GJ, Wichers JH, Ferreira TM, Ghati D, van Amerongen A, Deelder AM, 2004. Diagnosis of schistosomiasis by reagent strip test for detection of circulating cathodic antigen. J Clin Microbiol 42: 5458–5461.
-
21.
Wambura M, Urassa M, Isingo R, Ndege M, Marston M, Slaymaker E, Mngara J, Changalucha J, Boerma TJ, Zaba B, 2007. HIV prevalence and incidence in rural Tanzania: results from 10 years of follow-up in an open-cohort study. J Acquir Immune Defic Syndr 46: 616–623.
-
22.
Amsel R, Totten PA, Spiegel CA, Chen KC, Eschenbach D, Holmes KK, 1983. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 74: 14–22.
-
23.
De Jonge N, Gryseels B, Hilberath GW, Polderman AM, Deelder AM, 1988. Detection of circulating anodic antigen by ELISA for seroepidemiology of schistosomiasis mansoni. Trans R Soc Trop Med Hyg 82: 591–594.
-
24.
de Jonge N, De Caluwe P, Hilberath GW, Krijger FW, Polderman AM, Deelder AM, 1989. Circulating anodic antigen levels in serum before and after chemotherapy with praziquantel in schistosomiasis mansoni. Trans R Soc Trop Med Hyg 83: 368–372.
-
25.
Polman K, de Vlas SJ, Gryseels B, Deelder AM, 2000. Relating serum circulating anodic antigens to faecal egg counts in Schistosoma mansoni infections: a modelling approach. Parasitology 121: 601–610.
-
26.
Jonckheere AR, 1954. A distribution-free k-sample test against ordered alternatives. Biometrika 41: 133–145.
-
27.
Siddappa NB, Hemashettar G, Shanmuganathan V, Semenya AA, Sweeney ED, Paul KS, Lee SJ, Secor WE, Ruprecht RM, 2011. Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 clade C SHIV. PLoS Negl Trop Dis 5: e1270.
-
28.
Shainheit MG, Smith PM, Bazzone LE, Wang AC, Rutitzky LI, Stadecker MJ, 2008. Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology. J Immunol 181: 8559–8567.
-
29.
Rutitzky LI, Bazzone L, Shainheit MG, Joyce-Shaikh B, Cua DJ, Stadecker MJ, 2008. IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17. J Immunol 180: 2486–2495.
-
30.
Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, Scheinberg P, Price DA, Hage CA, Kholi LM, Khoruts A, Frank I, Else J, Schacker T, Silvestri G, Douek DC, 2008. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112: 2826–2835.
-
31.
McKinnon LR, Nyanga B, Chege D, Izulla P, Kimani M, Huibner S, Gelmon L, Block KE, Cicala C, Anzala AO, Arthos J, Kimani J, Kaul R, 2011. Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility. J Immunol 187: 6032–6042.
-
32.
Stabinski L, Reynolds SJ, Ocama P, Laeyendecker O, Ndyanabo A, Kiggundu V, Boaz I, Gray RH, Wawer M, Thio C, Thomas DL, Quinn TC, Kirk GD, Rakai Health Sciences Program, 2011. High prevalence of liver fibrosis associated with HIV infection: a study in rural Rakai, Uganda. Antivir Ther 16: 405–411.
-
33.
Secor WE, 2012. The effects of schistosomiasis on HIV/AIDS infection, progression and transmission. Curr Opin HIV AIDS 7: 254–259.
-
34.
Secor WE, Shah A, Mwinzi PM, Ndenga BA, Watta CO, Karanja DM, 2003. Increased density of human immunodeficiency virus type 1 coreceptors CCR5 and CXCR4 on the surfaces of CD4(+) T cells and monocytes of patients with Schistosoma mansoni infection. Infect Immun 71: 6668–6671.
-
35.
Kallestrup P, Zinyama R, Gomo E, Butterworth AE, Mudenge B, van Dam GJ, Gerstoft J, Erikstrup C, Ullum H, 2005. Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA load. J Infect Dis 192: 1956–1961.
-
36.
Lawn SD, Karanja DM, Mwinzia P, Andove J, Colley DG, Folks TM, Secor WE, 2000. The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals. AIDS 14: 2437–2443.
-
37.
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH, 2005. Treatment of intestinal helminths does not reduce plasma concentrations of HIV-1 RNA in coinfected Zambian adults. J Infect Dis 192: 1277–1283.
-
38.
Secor WE, 2005. Immunology of human schistosomiasis: off the beaten path. Parasite Immunol 27: 309–316.
-
39.
Todd J, Grosskurth H, Changalucha J, Obasi A, Mosha F, Balira R, Orroth K, Hugonnet S, Pujades M, Ross D, Gavyole A, Mabey D, Hayes R, 2006. Risk factors influencing HIV infection incidence in a rural African population: a nested case-control study. J Infect Dis 193: 458–466.
-
40.
van Dam GJ, Bogitsh BJ, van Zeyl RJ, Rotmans JP, Deelder AM, 1996. Schistosoma mansoni: in vitro and in vivo excretion of CAA and CCA by developing schistosomula and adult worms. J Parasitol 82: 557–564.
-
41.
Kremsner PG, Enyong P, Krijger FW, De Jonge N, Zotter GM, Thalhammer F, Muhlschlegel F, Bienzle U, Feldmeier H, Deelder AM, 1994. Circulating anodic and cathodic antigen in serum and urine from Schistosoma haematobium-infected cameroonian children receiving praziquantel: a longitudinal study. Clin Infect Dis 18: 408–413.
-
42.
van Lieshout L, Polderman AM, Deelder AM, 2000. Immunodiagnosis of schistosomiasis by determination of the circulating antigens CAA and CCA, in particular in individuals with recent or light infections. Acta Trop 77: 69–80.
-
43.
Karanja DM, Hightower AW, Colley DG, Mwinzi PN, Galil K, Andove J, Secor WE, 2002. Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility to schistosomiasis: a longitudinal study. Lancet 360: 592–596.
-
44.
Trushin P, Bang H, 2010. The role of epidemiology and biostatistics in health news reporting. Finkel M, ed. Public Health in the 21st Century. Santa Barbara, CA: ABC-CLIO, LLC.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 877 | 807 | 273 |
| Full Text Views | 729 | 19 | 1 |
| PDF Downloads | 240 | 9 | 0 |