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1.
Currie BJ, Fisher DA, Howard DM, Burrow JN, Lo D, Selva-Nayagam S, Anstey NM, Huffam SE, Snelling PL, Marks PJ, Stephens DP, Lum GD, Jacups SP, Krause VL, 2000. Endemic melioidosis in tropical Northern Australia: a 10 year prospective study and review of the literature. Clin Infect Dis 31: 981– 986.
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2.
Puthucheary SD, Parasakthi N, Lee MK, 1992. Septicemic melioidosis: a review of 50 cases from Malaysia. Trans R Soc Med Hyg 86: 683– 685.
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3.
How SH, Ng KH, Jamalludin AR, Shah A, Rathor Y, 2005. Melioidosis in Pahang. Malaysia Med J 60: 606– 613.
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4.
Suputtamongkol Y, Hall AJ, Dance DA, Chaowagul W, Rajchanuvong A, Smith MD, White NJ, 1994. The epidemiology of melioidosis in Ubon Ratchatani, Northern Eastern Thailand. Int J Epidemiol 23: 1082– 1089.
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5.
Heng BH, Goh KT, Yap EH, Loh H, Yeo M, 1998. Epidemiological surveillance of melioidosis in Singapore. Ann Acad Med Singapore 27: 478– 484.
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6.
Lu PL, Tseng SH, 2005. Fatal septicemic melioidosis in a young military person possibly co-infected with Leptospira interrogans and Orientia tsutsugamushi. Kashsiung J Mec Sci 21: 173– 177.
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7.
Inglis TJ, Garrow SC, Adams C, Henderson M, Mayo M, Currie BJ, 1999. Acute melioidosis outbreak in Western Australia. Epidemiol Infect 123: 437– 443.
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Ko WC, Cheung BM, Tang HJ, Shih HI, Lau YJ, Wang LR, Chuang YC, 2007. Melioidosis outbreak after Typhoon, Southern Taiwan. Emerg Infect Dis 6: 896– 898.
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Dale Everett E, 2010. Microbiology, Epidemiology, Clinical Manifestation and Diagnosis of Leptospirosis. Available at http://www.uptodate.com/online/content/topic.do?topicKey=bact/41944&view=print. Accessed August 13, 2010.
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Fonseca C de A, Teixeira MM, Romero EC, Tengan FM, Silva MV, Shikanai-Yasuda MA, 2006. Leptospira DNA detection for the diagnosis of human leptospirosis. J Infect 52: 15– 22.
| Past two years | Past Year | Past 30 Days | |
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Fatal Co-Infection–Melioidosis and Leptospirosis
How Soon Hin
How Soon Hin
Department of Internal Medicine, International Islamic University Malaysia, Kuantan, Malaysia; Department of Medicine, Hospital Sultan Haji Ahmad Shah, Temerloh, Malaysia; Department of Community Health, International Islamic University Malaysia, Kuantan, Malaysia; Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia; Pahang State Health Department, Kuantan, Malaysia
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Rajalingam Ramalingam
Rajalingam Ramalingam
Department of Internal Medicine, International Islamic University Malaysia, Kuantan, Malaysia; Department of Medicine, Hospital Sultan Haji Ahmad Shah, Temerloh, Malaysia; Department of Community Health, International Islamic University Malaysia, Kuantan, Malaysia; Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia; Pahang State Health Department, Kuantan, Malaysia
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Kuan Yeh Chunn
Kuan Yeh Chunn
Department of Internal Medicine, International Islamic University Malaysia, Kuantan, Malaysia; Department of Medicine, Hospital Sultan Haji Ahmad Shah, Temerloh, Malaysia; Department of Community Health, International Islamic University Malaysia, Kuantan, Malaysia; Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia; Pahang State Health Department, Kuantan, Malaysia
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Norazah Ahmad
Norazah Ahmad
Department of Internal Medicine, International Islamic University Malaysia, Kuantan, Malaysia; Department of Medicine, Hospital Sultan Haji Ahmad Shah, Temerloh, Malaysia; Department of Community Health, International Islamic University Malaysia, Kuantan, Malaysia; Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia; Pahang State Health Department, Kuantan, Malaysia
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Jamalludin Ab Rahman
Jamalludin Ab Rahman
Department of Internal Medicine, International Islamic University Malaysia, Kuantan, Malaysia; Department of Medicine, Hospital Sultan Haji Ahmad Shah, Temerloh, Malaysia; Department of Community Health, International Islamic University Malaysia, Kuantan, Malaysia; Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia; Pahang State Health Department, Kuantan, Malaysia
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Mohd Sapian Mohamed
Mohd Sapian Mohamed
Department of Internal Medicine, International Islamic University Malaysia, Kuantan, Malaysia; Department of Medicine, Hospital Sultan Haji Ahmad Shah, Temerloh, Malaysia; Department of Community Health, International Islamic University Malaysia, Kuantan, Malaysia; Bacteriology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia; Pahang State Health Department, Kuantan, Malaysia
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Co-infection of melioidosis and leptospirosis is uncommon. We report here four such cases, confirmed by blood culture for melioidosis and blood polymerase-chain reaction for leptospirosis, which occurred among rescuers involved in a search and rescue operation for a young man who was suspected to have drowned in Lubuk Yu, a recreational forest in Pahang, Malaysia. Despite treatment, three of the patients died from the co-infection.
Author Notes
Authors' addresses: How Soon Hin and Kuan Yeh Chunn, Department of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Kuantan, Pahang, Malaysia, E-mails: how_sh@yahoo.com and kychunn@yahoo.com. Rajalingam Ramalingam, Hospital Sultan Haji Ahmad Shah, Jalan Maran, Temerloh, Pahang, Malaysia, E-mail: raj.blueheart@gmail.com. Norazah Ahmad, Institute for Medical Research, Kuantan, Pahang, Malaysia, E-mail: norazah@imr.gov.my. Jamalludin Ab Rahman, Department of Community Health, Kulliyyah of Medicine, International Islamic University Malaysia, Pahang, Malaysia, E-mail: arjamal@iium.edu.my. Mohd Sapian Mohamed, Pahang State Health Department, Kuantan, Pahang, Malaysia, E-mail: drhjsapian26@phg.moh.gov.my.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Currie BJ, Fisher DA, Howard DM, Burrow JN, Lo D, Selva-Nayagam S, Anstey NM, Huffam SE, Snelling PL, Marks PJ, Stephens DP, Lum GD, Jacups SP, Krause VL, 2000. Endemic melioidosis in tropical Northern Australia: a 10 year prospective study and review of the literature. Clin Infect Dis 31: 981– 986.
-
2.
Puthucheary SD, Parasakthi N, Lee MK, 1992. Septicemic melioidosis: a review of 50 cases from Malaysia. Trans R Soc Med Hyg 86: 683– 685.
-
3.
How SH, Ng KH, Jamalludin AR, Shah A, Rathor Y, 2005. Melioidosis in Pahang. Malaysia Med J 60: 606– 613.
-
4.
Suputtamongkol Y, Hall AJ, Dance DA, Chaowagul W, Rajchanuvong A, Smith MD, White NJ, 1994. The epidemiology of melioidosis in Ubon Ratchatani, Northern Eastern Thailand. Int J Epidemiol 23: 1082– 1089.
-
5.
Heng BH, Goh KT, Yap EH, Loh H, Yeo M, 1998. Epidemiological surveillance of melioidosis in Singapore. Ann Acad Med Singapore 27: 478– 484.
-
6.
Lu PL, Tseng SH, 2005. Fatal septicemic melioidosis in a young military person possibly co-infected with Leptospira interrogans and Orientia tsutsugamushi. Kashsiung J Mec Sci 21: 173– 177.
-
7.
Inglis TJ, Garrow SC, Adams C, Henderson M, Mayo M, Currie BJ, 1999. Acute melioidosis outbreak in Western Australia. Epidemiol Infect 123: 437– 443.
-
8.
Ko WC, Cheung BM, Tang HJ, Shih HI, Lau YJ, Wang LR, Chuang YC, 2007. Melioidosis outbreak after Typhoon, Southern Taiwan. Emerg Infect Dis 6: 896– 898.
-
9.
Dale Everett E, 2010. Microbiology, Epidemiology, Clinical Manifestation and Diagnosis of Leptospirosis. Available at http://www.uptodate.com/online/content/topic.do?topicKey=bact/41944&view=print. Accessed August 13, 2010.
-
10.
Fonseca C de A, Teixeira MM, Romero EC, Tengan FM, Silva MV, Shikanai-Yasuda MA, 2006. Leptospira DNA detection for the diagnosis of human leptospirosis. J Infect 52: 15– 22.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1844 | 1641 | 40 |
| Full Text Views | 406 | 3 | 0 |
| PDF Downloads | 131 | 4 | 0 |