ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
McEwen JG, Garcia AM, Ortiz BL, Botero S, Restrepo A, 1995. In search of the natural habitat of Paracoccidioides brasiliensis. Arch Med Res Autumn 26: 305– 306.
-
2.
Restrepo A, Baumgardner DJ, Bagagli E, Cooper CR Jr, Mcginnis MR, Lázera MS, Barbosa FH, Bosco SM, Camargo ZP, Coelho KI, Fortes ST, Franco M, Montenegro MR, Sano A, Wanke B, 2000. Clues to the presence of pathogenic fungi in certain environments. Med Mycol 38 (Suppl 1): 67– 77.
-
3.
Bellissimo-Rodrigues F, Machado AA, Martinez R, 2011. Paracoccidioidomycosis epidemiological features of a 1,000-cases series from a hyperendemic area on the Southeast of Brazil. Am J Trop Med Hyg 85: 546– 550.
-
4.
Brummer E, Castaneda E, Restrepo A, 1993. Paracoccidioidomycosis: an update. Clin Microbiol Rev 6: 89– 117.
-
5.
Matute DR, Mcewen JG, Puccia R, Montes BA, San-Blas G, Bagagli E, Rauscher JT, Restrepo A, Morais F, Niño-Vega G, Taylor JW, 2006. Cryptic speciation and recombination in the fungus Paracoccidioides brasiliensis as revealed by gene genealogies. Mol Biol Evol 23: 65– 73.
-
6.
Carrero LL, Niño-Vega G, Teixeira MM, Carvalho MJ, Soares CM, Pereira M, Jesuíno RS, Mcewen JG, Mendoza L, Taylor JW, Felipe MS, San-Blas G, 2008. New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen. Fungal Genet Biol 45: 605– 612.
-
7.
Theodoro RC, Bagagli E, Oliveira C, 2008. Phylogenetic analysis of PRP8 intein in Paracoccidioides brasiliensis species complex. Fungal Genet Biol 45: 1284– 1291.
-
8.
Teixeira MM, Theodoro RC, de Carvalho MJ, Fernandes L, Paes HC, Hahn RC, Mendoza L, Bagagli E, San-Blas G, Felipe MS, 2009. Phylogenetic analysis reveals a high level of speciation in the Paracoccidioides genus. Mol Phylogenet Evol 52: 273– 283.
-
9.
Hahn RC, Macedo AM, Santos NL, Resende JC, Hamdan JS, 2002. Characterization of Paracoccidioides brasiliensis atypical isolates by random amplified polymorphic DNA analysis. Rev Iberoam Micol 19: 49– 51.
-
10.
Takayama A, Itano EN, Sano A, Ono MA, Kamei K, 2010. An atypical Paracoccidioides brasiliensis clinical isolate based on multiple gene analysis. Med Mycol 48: 64– 72.
-
11.
Fava-Netto C, Vegas VS, Scianaméia IM, Guarnieri DB, 1969. The polysaccharidic antigen from Paracoccidioides brasiliensis. Study of the time of cultivation necessary for the preparation of the antigen. Rev Inst Med Trop Sao Paulo 11: 177– 181.
-
12.
Cisalpino PS, Puccia R, Yamauchi LM, Cano MI, Da Silveira JF, Travassos LR, 1996. Cloning, characterization, and epitope expression of the major diagnostic antigen of Paracoccidioides brasiliensis. J Biol Chem 271: 4553– 4560.
-
13.
Kasuga T, White TJ, Taylor JW, 2002. Estimation of nucleotide substitution rates in Eurotiomycete fungi. Mol Biol Evol 19: 2318– 2324.
-
14.
Thompson JD, Higgins DG, Gibson TJ, 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673– 4680.
-
15.
Hall TA, 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp Ser 41: 95– 98.
-
16.
Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S, 2011. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and mParsimony methods. Mol Biol Evol 28: 2731– 2739.
-
17.
Kimura M, 1980. A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16: 111– 120.
-
18.
Felsenstein J, 1985. Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39: 783– 791.
-
19.
De Vienne DM, Giraud T, Martin OC, 2007. A congruence index for testing topological similarity between trees. Bioinformatics 23: 3119– 3124.
-
20.
Marques-da-Silva SH, Colombo AL, Blotta MHSL, Lopes JD, Telles FQ, Camargo ZP, 2003. Detection of circulating gp43 antigen in serum, cerebrospinal fluid, and bronchoalveolar lavage fluid of patients with paracoccidioidomycosis. J Clin Microbiol 41: 3675– 3680.
-
21.
Carvalho KC, Vallejo MC, Camargo ZP, Puccia R, 2008. Use of recombinant gp43 isoforms expressed in Pichia pastoris for diagnosis of paracoccidioidomycosis. Clin Vaccine Immunol 15: 622– 629.
-
22.
Silveira-Gomes F, Sarmento DN, Pinto TM, Pimentel RF, Nepomuceno LB, Espírito Santo EP, Mesquita-da-Costa M, Camargo ZP, Marques-da-Silva SH, 2011. Development and evaluation of a latex agglutination test for the serodiagnosis of paracoccidioidomycosis. Clin Vaccine Immunol 18: 604– 608.
-
23.
Marques SA, Robles AM, Tortorano AM, Tuculet MA, Negroni R, Mendes RP, 2000. Mycoses associated with AIDS in the Third World. Med Mycol 38 (Suppl 1): 269– 279.
-
24.
Bellissimo-Rodrigues F, Vitali LH, Martinez R, 2010. Serological diagnosis of paracoccidioidomycosis in HIV-coinfected patients. Mem Inst Oswaldo Cruz, Rio de Janeiro 105: 904– 907.
-
25.
Mendes-Giannini MJ, Bueno JP, Shikanai-Yasuda MA, Ferreira AW, Masuda A, 1989. Detection of the 43,000-molecular-weight glycoprotein in sera of patients with paracoccidioidomycosis. J Clin Microbiol 27: 2842– 2845.
-
26.
Freitas da Silva G, Roque-Barreira MC, 1992. Antigenemia in paracoccidioidomycosis. J Clin Microbiol 30: 381– 385.
-
27.
Mendes-Giannini MJS, Del Negro GM, Siqueira AM, 1994. Serodiagnosis. Franco MF, Lacaz CS, Restrepo A, Del Negro G, eds. Paracoccidioidomycosis. Boca Raton, FL: CRC Press, 345– 363.
-
28.
Batista J Jr, Camargo ZP, Fernandes GF, Vicentini AP, Fontes CJ, Hahn RC, 2009. Is the geographical origin of a Paracoccidioides brasiliensis isolate important for antigen production for regional diagnosis of paracoccidioidomycosis? Mycoses 53: 176– 180.
-
29.
Camargo ZC, Berzaghi R, Amaral CC, Marques-da-Silva SH, 2003. Simplified method for producing Paracoccidioides brasiliensis exoantigens for use in immunodiffusion tests. Med Mycol 41: 539– 542.
-
30.
Sano A, Defaveri J, Tanaka R, Yokoyama K, Kurita N, Franco M, Coelho KI, Bagagli E, Montenegro MR, Miyaji M, Nishimura K, 1999. Pathogenicities and GP43kDa gene of three Paracoccidioides brasiliensis isolates originated from a nine-banded armadillo (Dasypus novemcinctus). Mycopathologia 144: 61– 65.
-
31.
Morais FV, Barros TF, Fukada MK, Cisalpino PS, Puccia R, 2000. Polymorphism in the gene coding for the immunodominant antigen gp43 from the pathogenic fungus Paracoccidioides brasiliensis. J Clin Microbiol 38: 3960– 3966.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 568 | 383 | 41 |
| Full Text Views | 347 | 2 | 0 |
| PDF Downloads | 82 | 4 | 0 |
Occurrence of Paracoccidioides lutzii in the Amazon Region: Description of Two Cases
Silvia Helena Marques-da-Silva
Silvia Helena Marques-da-Silva
Evandro Chagas Institute, Bacteriology and Mycology Section, Mycology Laboratory, Ananindeua, Pará, Brazil; Federal University of São Paulo (UNIFESP), Department of Microbiology, Immunology, and Parasitology, São Paulo, Brazil; CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; Federal University of Pará, Science Biologic Institute, Belém, Pará, Brazil
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Anderson Messias Rodrigues
Anderson Messias Rodrigues
Evandro Chagas Institute, Bacteriology and Mycology Section, Mycology Laboratory, Ananindeua, Pará, Brazil; Federal University of São Paulo (UNIFESP), Department of Microbiology, Immunology, and Parasitology, São Paulo, Brazil; CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; Federal University of Pará, Science Biologic Institute, Belém, Pará, Brazil
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G. Sybren de Hoog
G. Sybren de Hoog
Evandro Chagas Institute, Bacteriology and Mycology Section, Mycology Laboratory, Ananindeua, Pará, Brazil; Federal University of São Paulo (UNIFESP), Department of Microbiology, Immunology, and Parasitology, São Paulo, Brazil; CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; Federal University of Pará, Science Biologic Institute, Belém, Pará, Brazil
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Fabíola Silveira-Gomes
Fabíola Silveira-Gomes
Evandro Chagas Institute, Bacteriology and Mycology Section, Mycology Laboratory, Ananindeua, Pará, Brazil; Federal University of São Paulo (UNIFESP), Department of Microbiology, Immunology, and Parasitology, São Paulo, Brazil; CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; Federal University of Pará, Science Biologic Institute, Belém, Pará, Brazil
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Zoilo Pires de Camargo
Zoilo Pires de Camargo
Evandro Chagas Institute, Bacteriology and Mycology Section, Mycology Laboratory, Ananindeua, Pará, Brazil; Federal University of São Paulo (UNIFESP), Department of Microbiology, Immunology, and Parasitology, São Paulo, Brazil; CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; Federal University of Pará, Science Biologic Institute, Belém, Pará, Brazil
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Paracoccidioidomycosis (PCM), the most important human systemic mycosis in Latin America, is known to be caused by at least four different phylogenetic lineages within the Paracoccidioides brasiliensis complex, including S1, PS2, PS3, and Pb01-like group. Herein, we describe two cases of PCM in patients native from the Amazon region. The disease was originally thought to have been caused by P. brasiliensis. Despite the severity of the cases, sera from the patients were negative in immunodiffusion tests using the standard exoantigen from P. brasiliensis B-339. However, a positive response was recorded with an autologous preparation of Paracoccidioides lutzii exoantigen. A phylogenetic approach based on the gp43 and ARF loci revealed high similarity between our clinical isolates and the Pb01-like group. The occurrence of PCM caused by P. lutzii in the Brazilian Amazon (Pará State) was thus proven. The incidence of PCM caused by P. lutzii may be underestimated in northern Brazil.
Author Notes
Financial support: A. M. Rodrigues is a fellow and acknowledges the financial support of the Fundação de Amparo à Pesquisa do Estado de São Paulo (2011/07350-1) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (BEX 2325/11-0). Z. P. de Camargo thanks the financial support received from FAPESP (2009/54024-2).
Authors' addresses: Silvia Helena Marques-da-Silva, Instituto Evandro Chagas – IEC/SVS/MS, Seção de Bacteriologia e Micologia, Ananindeua, Pará-Brasil, E-mail: silviasilva@iec.pa.gov.br. Anderson Messias Rodrigues, Universidade Federal de São Paulo (UNIFESP), Departamento de Microbiologia, Imunologia e Parasitologia, São Paulo, São Paulo- Brazil, and CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands, E-mail: rodrigues_bio@yahoo.com.br. G. Sybren de Hoog, CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands, E-mail: s.hoog@cbs.knaw.nl. Fabíola Silveira-Gomes, Universidade Federal do Pará, Instituto de Ciências Biológicas, Belém, Pará- Brazil, E-mail: fabiolagomes@ufpa.br. Zoilo Pires de Camargo, Universidade Federal de São Paulo (UNIFESP), Departamento de Microbiologia, Imunologia e Parasitologia, São Paulo, São Paulo- Brasil, E-mail: zpcamargo@unifesp.br.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
McEwen JG, Garcia AM, Ortiz BL, Botero S, Restrepo A, 1995. In search of the natural habitat of Paracoccidioides brasiliensis. Arch Med Res Autumn 26: 305– 306.
-
2.
Restrepo A, Baumgardner DJ, Bagagli E, Cooper CR Jr, Mcginnis MR, Lázera MS, Barbosa FH, Bosco SM, Camargo ZP, Coelho KI, Fortes ST, Franco M, Montenegro MR, Sano A, Wanke B, 2000. Clues to the presence of pathogenic fungi in certain environments. Med Mycol 38 (Suppl 1): 67– 77.
-
3.
Bellissimo-Rodrigues F, Machado AA, Martinez R, 2011. Paracoccidioidomycosis epidemiological features of a 1,000-cases series from a hyperendemic area on the Southeast of Brazil. Am J Trop Med Hyg 85: 546– 550.
-
4.
Brummer E, Castaneda E, Restrepo A, 1993. Paracoccidioidomycosis: an update. Clin Microbiol Rev 6: 89– 117.
-
5.
Matute DR, Mcewen JG, Puccia R, Montes BA, San-Blas G, Bagagli E, Rauscher JT, Restrepo A, Morais F, Niño-Vega G, Taylor JW, 2006. Cryptic speciation and recombination in the fungus Paracoccidioides brasiliensis as revealed by gene genealogies. Mol Biol Evol 23: 65– 73.
-
6.
Carrero LL, Niño-Vega G, Teixeira MM, Carvalho MJ, Soares CM, Pereira M, Jesuíno RS, Mcewen JG, Mendoza L, Taylor JW, Felipe MS, San-Blas G, 2008. New Paracoccidioides brasiliensis isolate reveals unexpected genomic variability in this human pathogen. Fungal Genet Biol 45: 605– 612.
-
7.
Theodoro RC, Bagagli E, Oliveira C, 2008. Phylogenetic analysis of PRP8 intein in Paracoccidioides brasiliensis species complex. Fungal Genet Biol 45: 1284– 1291.
-
8.
Teixeira MM, Theodoro RC, de Carvalho MJ, Fernandes L, Paes HC, Hahn RC, Mendoza L, Bagagli E, San-Blas G, Felipe MS, 2009. Phylogenetic analysis reveals a high level of speciation in the Paracoccidioides genus. Mol Phylogenet Evol 52: 273– 283.
-
9.
Hahn RC, Macedo AM, Santos NL, Resende JC, Hamdan JS, 2002. Characterization of Paracoccidioides brasiliensis atypical isolates by random amplified polymorphic DNA analysis. Rev Iberoam Micol 19: 49– 51.
-
10.
Takayama A, Itano EN, Sano A, Ono MA, Kamei K, 2010. An atypical Paracoccidioides brasiliensis clinical isolate based on multiple gene analysis. Med Mycol 48: 64– 72.
-
11.
Fava-Netto C, Vegas VS, Scianaméia IM, Guarnieri DB, 1969. The polysaccharidic antigen from Paracoccidioides brasiliensis. Study of the time of cultivation necessary for the preparation of the antigen. Rev Inst Med Trop Sao Paulo 11: 177– 181.
-
12.
Cisalpino PS, Puccia R, Yamauchi LM, Cano MI, Da Silveira JF, Travassos LR, 1996. Cloning, characterization, and epitope expression of the major diagnostic antigen of Paracoccidioides brasiliensis. J Biol Chem 271: 4553– 4560.
-
13.
Kasuga T, White TJ, Taylor JW, 2002. Estimation of nucleotide substitution rates in Eurotiomycete fungi. Mol Biol Evol 19: 2318– 2324.
-
14.
Thompson JD, Higgins DG, Gibson TJ, 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673– 4680.
-
15.
Hall TA, 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp Ser 41: 95– 98.
-
16.
Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S, 2011. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and mParsimony methods. Mol Biol Evol 28: 2731– 2739.
-
17.
Kimura M, 1980. A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16: 111– 120.
-
18.
Felsenstein J, 1985. Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39: 783– 791.
-
19.
De Vienne DM, Giraud T, Martin OC, 2007. A congruence index for testing topological similarity between trees. Bioinformatics 23: 3119– 3124.
-
20.
Marques-da-Silva SH, Colombo AL, Blotta MHSL, Lopes JD, Telles FQ, Camargo ZP, 2003. Detection of circulating gp43 antigen in serum, cerebrospinal fluid, and bronchoalveolar lavage fluid of patients with paracoccidioidomycosis. J Clin Microbiol 41: 3675– 3680.
-
21.
Carvalho KC, Vallejo MC, Camargo ZP, Puccia R, 2008. Use of recombinant gp43 isoforms expressed in Pichia pastoris for diagnosis of paracoccidioidomycosis. Clin Vaccine Immunol 15: 622– 629.
-
22.
Silveira-Gomes F, Sarmento DN, Pinto TM, Pimentel RF, Nepomuceno LB, Espírito Santo EP, Mesquita-da-Costa M, Camargo ZP, Marques-da-Silva SH, 2011. Development and evaluation of a latex agglutination test for the serodiagnosis of paracoccidioidomycosis. Clin Vaccine Immunol 18: 604– 608.
-
23.
Marques SA, Robles AM, Tortorano AM, Tuculet MA, Negroni R, Mendes RP, 2000. Mycoses associated with AIDS in the Third World. Med Mycol 38 (Suppl 1): 269– 279.
-
24.
Bellissimo-Rodrigues F, Vitali LH, Martinez R, 2010. Serological diagnosis of paracoccidioidomycosis in HIV-coinfected patients. Mem Inst Oswaldo Cruz, Rio de Janeiro 105: 904– 907.
-
25.
Mendes-Giannini MJ, Bueno JP, Shikanai-Yasuda MA, Ferreira AW, Masuda A, 1989. Detection of the 43,000-molecular-weight glycoprotein in sera of patients with paracoccidioidomycosis. J Clin Microbiol 27: 2842– 2845.
-
26.
Freitas da Silva G, Roque-Barreira MC, 1992. Antigenemia in paracoccidioidomycosis. J Clin Microbiol 30: 381– 385.
-
27.
Mendes-Giannini MJS, Del Negro GM, Siqueira AM, 1994. Serodiagnosis. Franco MF, Lacaz CS, Restrepo A, Del Negro G, eds. Paracoccidioidomycosis. Boca Raton, FL: CRC Press, 345– 363.
-
28.
Batista J Jr, Camargo ZP, Fernandes GF, Vicentini AP, Fontes CJ, Hahn RC, 2009. Is the geographical origin of a Paracoccidioides brasiliensis isolate important for antigen production for regional diagnosis of paracoccidioidomycosis? Mycoses 53: 176– 180.
-
29.
Camargo ZC, Berzaghi R, Amaral CC, Marques-da-Silva SH, 2003. Simplified method for producing Paracoccidioides brasiliensis exoantigens for use in immunodiffusion tests. Med Mycol 41: 539– 542.
-
30.
Sano A, Defaveri J, Tanaka R, Yokoyama K, Kurita N, Franco M, Coelho KI, Bagagli E, Montenegro MR, Miyaji M, Nishimura K, 1999. Pathogenicities and GP43kDa gene of three Paracoccidioides brasiliensis isolates originated from a nine-banded armadillo (Dasypus novemcinctus). Mycopathologia 144: 61– 65.
-
31.
Morais FV, Barros TF, Fukada MK, Cisalpino PS, Puccia R, 2000. Polymorphism in the gene coding for the immunodominant antigen gp43 from the pathogenic fungus Paracoccidioides brasiliensis. J Clin Microbiol 38: 3960– 3966.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 568 | 383 | 41 |
| Full Text Views | 347 | 2 | 0 |
| PDF Downloads | 82 | 4 | 0 |