ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Schwenkenbecher JM, Wirth T, Schnur LF, Jaffe CL, Schallig H, Al-Jawabreh A, Hamarsheh O, Azmi K, Pratlong F, Schönian G, 2006. Microsatellite analysis reveals genetic structure of Leishmania tropica. Int J Parasitol 36 : 237– 246.
-
2.
WHO, 1984. The leishmaniasis. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser 701 : 1– 140.
-
3.
Svobodova M, Votypka J, Peckova J, Dvorak V, Nasereddin A, Baneth G, Sztern J, Kravchenko V, Orr A, Meir D, Schnur LF, Volf P, Warburg A, 2006. Distinct transmission cycles of Leishmania tropica in 2 adjacent foci, northern Israel. Emerg Infect Dis 12 : 1860– 1868.
-
4.
Talmi-Frank D, Jaffe CL, Nasereddin A, Warburg A, King R, Svobodova M, Peleg O, Baneth G, 2010. Leishmania tropica in rock hyraxes (Procavia capensis) in a focus of human cutaneous leishmaniasis. Am J Trop Med Hyg 82 : 814– 818.
-
5.
Sang DK, Njeru WK, Ashford RW, 1994. A zoonotic focus of cutaneous leishmaniasis due to Leishmania tropica at Utut, Fift Valley Province, Kenya. Trans R Soc Trop Med Hyg 88 : 35– 37.
-
6.
Svobodová M, Volf P, Votýpka J, 2006. Experimental transmission of Leishmania tropica to hyraxes (Procavia capensis) by the bite of Phlebotomus arabicus. Microbes Infect 8 : 1691– 1694.
-
7.
Svobodová M, Votýpka J, Nicolas L, Volf P, 2003. Leishmania tropica in the black rat (Rattus rattus): persistence and transmission from asymptomatic host to sand fly vector Phlebotomus sergenti. Microbes Infect 5 : 361– 364.
-
8.
Bousslimi N, Aoun K, Ben-Abda I, Ben-Alaya-Bouafif N, Raouane M, Bouratbine A, 2010. Epidemiologic and clinical features of cutaneous leishmaniasis in southeastern Tunisia. Am J Trop Med Hyg 83 : 1034– 1039.
-
9.
Bouratbine A, Aoun K, Ghrab J, Harrat Z, Ezzedini MS, Etlijani S, 2005. Spread of Leishmania killicki to central and south-west Tunisia. Parasite 12 : 59– 63.
-
10.
Tabbabi A, Ghrab J, Aoun K, Ready PD, Bouratbine A, 2011. Habitats of the sandfly vectors of Leishmania tropica and L. major in a mixed focus of cutaneous leishmaniasis in southeast Tunisia. Acta Trop 119 : 131– 137.
-
11.
Tabbabi A, Bousslimi N, Rhim A, Aoun K, Bouratbine A, 2011. First report on natural infection of Phlebotomus sergenti with Leishmania promastigotes in the cutaneous leishmaniasis focus in southeastern Tunisia. Am J Trop Med Hyg 85 : 646– 647.
-
12.
Boubidi SC, Benallal K, Boudrissa A, Bouiba L, Bouchareb B, Garni R, Bouratbine A, Ravel C, Dvorak V, Votypka J, Volf P, Harrat Z, 2011. Phlebotomus sergenti (Parrot, 1917) identified as Leishmania killicki host in Ghardaïa, south Algeria. Microbes Infect 13 : 691– 696.
-
13.
Mary C, Faraut F, Lascombe L, Dumon H, 2004. Quantification of Leishmania infantum DNA by a real-time PCR assay with high sensitivity. J Clin Microbiol 42 : 5249– 5255.
-
14.
Schonian G, Nasereddin A, Dinse N, Schweynoch C, Schallig HD, Presber W, Jaffe CL, 2003. PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagn Microbiol Infect Dis 47 : 349– 358.
-
15.
Nasereddin A, Jaffe CL, 2010. Rapid diagnosis of Old World leishmaniasis by high-resolution melting analysis of the 7SL RNA gene. J Clin Microbiol 48 : 2240– 2242.
-
16.
Ashford RW, 1996. Leishmaniasis reservoirs and their significance in control. Clin Dermatol 14 : 523– 532.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 5 | 5 | 5 |
| Full Text Views | 386 | 139 | 2 |
| PDF Downloads | 94 | 26 | 0 |
Natural Infection of North African Gundi (Ctenodactylus gundi) by Leishmania tropica in the Focus of Cutaneous Leishmaniasis, Southeast Tunisia
North African gundis (Ctenodactylus gundi) were trapped in the Leishmania (L.) tropica focus of cutaneous leishmaniasis, situated in southeast Tunisia and evaluated for Leishmania infection by real-time kinetoplast DNA polymerase chain reaction (PCR). Species identification was performed by internal transcribed spacer one (ITS1)-PCR-restriction fragment length polymorphism (RFLP) and high-resolution melting (HRM) analysis of the 7SL RNA gene. Real-time PCR on blood was positive in 6 of 13 (46.2%) tested gundis. Leishmania tropica was identified in five infected gundis and Leishmania major in one specimen. Alignments of the ITS-1 DNA sequences and 7S-HRM curves analysis indicated that similar genotypes were present in humans, a sandfly, and gundis from the same region suggesting a potential role of this rodent as reservoir host of L. tropica in southeast Tunisia.
Author Notes
Financial support: This study was supported by the network of Pasteur Institutes (Actions Concertées Inter-Pasteuriennes, ACIP A 04 2007).
Authors' addresses: Nadia Bousslimi, Soumaya Ben-Ayed, Imène Ben-Abda, Karim Aoun, and Aïda Bouratbine, Laboratoire de Parasitologie, Institut Pasteur de Tunis, Tunis Belvédère, Tunisia, E-mails: nguetari@gmail.com, Soumayatba@yahoo.fr, benabda.imen@gmail.com, karim.aoun@pasteur.rns.tn, and aida.bouratbine@pasteur.rns.tn.