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Burden of Fasciola hepatica Infection among Children from Paucartambo in Cusco, Peru

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  • Laboratorio Clinico Ser Salud, Cusco, Peru; Infectious Diseases Division, University of Texas Medical Branch, Galveston, Texas; Tropical Medicine Institute, Universidad Peruana Cayetano Heredia, Lima, Peru

There is a high prevalence of fascioliasis in the Peruvian highlands, but most cases remain undiagnosed. The burden of disease caused by chronic subclinical infection is largely unknown. We studied school-age children from a district in Paucartambo Province in Cusco, Peru to evaluate the burden of disease caused by subclinical fascioliasis. Parasite eggs and/or larvae were identified in 46.2% of subjects, including Fasciola hepatica in 10.3% of subjects. Fascioliasis was independently associated with anemia (adjusted odds ratio = 3.01 [1.10–8.23]). Subclinical fascioliasis was common among children and strongly associated with anemia. Anemia should be recognized as an important component of the burden of disease from fascioliasis.

Author Notes

*Address correspondence to Miguel M. Cabada, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Avenida Honorio Delgado 430, San Martin de Porres, Lima, Peru. E-mail: micabada@utmb.edu

Financial support: No funding was received to performed this study

Authors' addresses: Martha Lopez, Laboratorio Clinico Ser Salud, Cusco, Peru, E-mail: martlop2000@gmail.com. A. Clinton White Jr., Infectious Diseases Division, University of Texas Medical Branch, Galveston, TX, E-mail: acwhite@utmb.edu. Miguel M. Cabada, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Peru, and Infectious Diseases Division, University of Texas Medical Branch, Galveston, TX, E-mail: micabada@utmb.edu.

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