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Unifocal Bone Paracoccidioidomycosis, Brazil

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  • Faculty of Medicine, Universidade Federal de Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil; Laboratório de Anatomia Patológica, Campo Grande, Mato Grosso do Sul, Brazil; Sonimed Campo Grande, Campo Grande, Mato Grosso do Sul, Brazil

We report a 47 year-old man from the State of Mato Grosso do Sul, Brazil, with unifocal tibial paracoccidioidomycosis. A radiograph showed an osteolytic lesion on the tibial middle third diaphysis. The diagnosis was confirmed by histopathologic analysis, and treatment with sulfamethoxazole and trimethoprim was started. After three months, the patient showed significant clinical improvement. Ten months after treatment, the patient showed lesion bone healing. This case describes the rare occurrence of an osteolytic lesion caused by endemic Paracoccidioides brasiliensis in Latin America.

Author Notes

*Address correspondence to Anamaria M. M. Paniago, Faculdade de Medicina, Hospital Universitário de Mato Grosso do Sul, MS, Avenida Senador Filinto Müller, 355, 79080-190, Campo Grande, MS, Brazil. E-mail: anapaniago@yahoo.com.br.

Authors' addresses: Bruna C. Castro, Mauricio A. Pompílio, and Anamaria M. M. Paniago, Faculdade de Medicina, Hospital Universitário de Mato Grosso do Sul, MS, Avenida Senador Filinto Müller, 1, 79080-190, Campo Grande, MS, Brazil, E-mails: brunacorreac@hotmail.com, mapompilio@yahoo.com.br, and anapaniago@yahoo.com.br. Danilo N. Odashiro and Maçanori Odashiro, Laboratório de Anatomia Patológica, Rua Rui Barbosa, 3716, 79.002-362, Campo Grande, MS, Brazil, E-mails: daniloodashiro@globo.com and macanoriodashiro@gmail.com. Adalberto Arão-Filho, Sonimed Campo Grande, Rua Dr Arthur Jorge, 1202, 79002-450, Campo Grande, MS, Brazil, E-mail: adalbertoarao@yahoo.com.br.

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