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Anemia and Helicobacter pylori Seroreactivity in a Rural Haitian Population

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  • Emory University School of Medicine, Atlanta, Georgia; Project Medishare, Thomonde, Haiti
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Anemia is a significant health concern worldwide and can be the result of nutritional, environmental, social, and infectious etiologies. We estimated the prevalence of anemia in 336 pre-school children and 132 adults in the rural Central Plateau of Haiti and assessed associations with age, sex, household size, water source, sanitation, and Helicobacter pylori seroreactivity using logistic regression analysis; 80.1% (269/336) of children and 63.6% (84/132) of adults were anemic. Among children, younger age was associated with increased prevalence of anemia (adjusted odds ratio [aOR] = 4.1, 95% confidence interval [CI] = 1.5–11.1 for children 6–11 months compared with children 48–59 months). Among adults, 50.8% were H. pylori-seropositive, and seropositivity was inversely associated with anemia (aOR = 0.4, 95% CI = 0.2–0.9). Anemia prevalence in this region of Haiti is very high and not attributable to sanitary conditions or a high prevalence of H. pylori infection.

Author Notes

*Address correspondence to Joshua R. Shak, Emory University School of Medicine, 1648 Pierce Drive, Room 374, Atlanta, GA 30322. E-mail: jshak@emory.edu

Financial support: This work was supported in part by National Institutes of Health Grant T32GM08169 (J.R.S. and R.A.S.). We thank Quidel Corporation for donating QuickVue Rapid Whole Blood Antibody Tests for use in this study; Quidel had no role in design of the study, interpretation of the data, preparation of the manuscript, or decision to publish.

Authors' addresses: Joshua R. Shak, Jamie B. Sodikoff, Rebecca A. Speckman, Francois G. Rollin, and Parminder S. Suchdev, Emory University School of Medicine, Atlanta, GA, E-mails: jshak@emory.edu, jsodiko@emory.edu, speckman.rebecca@gmail.com, frollin@gmail.com, and parminder.suchdev@emory.edu. Marie P. Chery, Project Medishare for Haiti, Miami, FL, E-mail: mariechery@gmail.com. Conrad R. Cole, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, E-mail: conrad.cole@cchmc.org.

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