ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Prescott JF, 1991. Rhodococcus equi: an animal and human pathogen. Clin Microbiol Rev 4: 20–34.
-
2.
Takai S, Tharavichitkul P, Takarn P, Khantawa B, Tamura M, Tsukamoto A, Takayama S, Yamatoda N, Kimura A, Sasaki Y, Kakuda T, Tsubaki S, Maneekarn N, Sirisanthana T, Kirikae T, 2003. Molecular epidemiology of Rhodococcus equi of intermediate virulence isolated from patients with and without acquired immune deficiency syndrome in Ching Mai, Thailand. J Infect Dis 188: 1717–1723.
-
3.
Weinstock DM, Brown AE, 2002. Rhodococcus equi: an emerging pathogen. Clin Infect Dis 34: 1379–1385.
-
4.
Takai S, 1997. Epidemiology of Rhodococcus equi infections: a review. Vet Microbiol 56: 167–176.
-
5.
Verville DT, Huicke MM, Greenfield RA, Fine DP, Kuhls TL, Slater LN, 1994. Rhodococcus equi infections of humans: 12 cases and literature review. Medicine 73: 119–132.
-
6.
Ribeiro MG, Seki I, Yasuoka K, Kakuda T, Sasaki Y, Tsubaki S, Takai S, 2005. Molecular epidemiology of virulent Rhodococcus equi from foals in Brazil: virulence plasmids of 85-kb type I, 87-kb type I, and a new variant, 87-kb type III. Comp Immunol Microbiol Infect Dis 28: 53–61.
-
7.
Takai S, Fukunga N, Ochiai S, Imai Y, Sasaki Y, Tsubaki S, Sekizaki T, 1996. Identification of intermediately virulent Rhodococcus equi isolates from pigs. J Clin Microbiol 34: 1034–1037.
-
8.
Quinn PJ, Carter ME, Markey B, Carter GR, 1994. Clinical Veterinary Microbiology. London: Wolfe, 137–143.
-
9.
Takai S, Ikeda T, Sasaki Y, Watanabe Y, Ozawa T, Tsubaki S, Sekizaki T, 1995. Identification of virulent Rhodococcus equi by amplification of gene coding for 15–17-kDa antigens. J Clin Microbiol 33: 1624–1627.
-
10.
Makrai L, Kobayashi A, Matsuoka M, Sasaki Y, Kakuda T, Dénes B, Hajtós I, Révész I, Jánosi K, Fodor L, Varga J, Takai S, 2008. Isolation and characterization of Rhodococcus equi from submaxillary lymph nodes of wild boars (Sus scrofa). Vet Microbiol 131: 318–323.
-
11.
Takai S, Sasaki Y, Ikeda T, Uchida Y, Tsubaki S, Sekizaki T, 1994. Virulence of Rhodococcus equi isolates from patients with and without AIDS. J Clin Microbiol 32: 457–460.
-
12.
Makrai L, Takai S, Tamura M, Tsukamoto A, Sekimoto R, Sasaki Y, Kakuda T, Tsubaki S, Varga J, Fodor L, Solymosi N, Major A, 2002. Characterization of virulence plasmids in Rhodococcus equi isolates from foals, pigs, humans and soil in Hungary. Vet Microbiol 88: 377–384.
-
13.
Ministério da Saúde Brazil, 2007. Programa Nacional de DST/AIDS. Brasilia: Secretaria de Vigilância em Saúde. Boletim Epidemiológico DST/AIDS.
-
14.
Silva P, Miyata M, Sato DN, Santos AC, Mendes NH, Leite CQ, 2010. Rhodococcus equi isolation from sputum of patients with suspected tuberculosis. Mem Inst Oswaldo Cruz 105: 199–202.
-
15.
Ribeiro MG, Takai S, Guazzelli A, Lara GH, Silva AV, Fernandes MC, Condas LAZ, Siqueira AK, Salerno T, 2010. Virulence genes and plasmid profiles in Rhodococcus equi isolates from domestic pig and wild boars (Sus scrofa) in Brazil. Res Vet Sci Oct 25 [Epub ahead of print].
-
16.
Costa MM, Machado SA, Krewer CC, Fighera RA, Ilha MR, Graça DL, Vargas AP, Mattos-Guaraldi AL, 2006. Pathogenecity of Rhodococcus equi isolates from human, horse clinical and environment in immunodeficient mice. Pesqui Vet Bras 26: 167–170.
-
17.
Napoleão F, Damasco PV, Camello TC, Vale MD, Andrade AF, Hirata R Jr, Mattos-Guaraldi AL, 2005. Pyogenic liver abscess due to Rhodococcus equi in an immunocompetent host. J Clin Microbiol 43: 1002–1004.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1152 | 1089 | 22 |
| Full Text Views | 1325 | 12 | 0 |
| PDF Downloads | 62 | 13 | 0 |
Identification of Virulence-Associated Plasmids in Rhodococcus equi in Humans with and without Acquired Immunodeficiency Syndrome in Brazil
Márcio Garcia Ribeiro
Márcio Garcia Ribeiro
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Márcio Garcia Ribeiro in
Current site
Google Scholar
PubMed
Search for other papers by Márcio Garcia Ribeiro in
Current site
Google Scholar
PubMed
Shinji Takai
Shinji Takai
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Shinji Takai in
Current site
Google Scholar
PubMed
Search for other papers by Shinji Takai in
Current site
Google Scholar
PubMed
Agueda Castagna de Vargas
Agueda Castagna de Vargas
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Agueda Castagna de Vargas in
Current site
Google Scholar
PubMed
Search for other papers by Agueda Castagna de Vargas in
Current site
Google Scholar
PubMed
Ana Luiza Mattos-Guaraldi
Ana Luiza Mattos-Guaraldi
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Ana Luiza Mattos-Guaraldi in
Current site
Google Scholar
PubMed
Search for other papers by Ana Luiza Mattos-Guaraldi in
Current site
Google Scholar
PubMed
Thereza Cristina Ferreira Camello
Thereza Cristina Ferreira Camello
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Thereza Cristina Ferreira Camello in
Current site
Google Scholar
PubMed
Search for other papers by Thereza Cristina Ferreira Camello in
Current site
Google Scholar
PubMed
Ryoko Ohno
Ryoko Ohno
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Ryoko Ohno in
Current site
Google Scholar
PubMed
Search for other papers by Ryoko Ohno in
Current site
Google Scholar
PubMed
Hajime Okano
Hajime Okano
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Hajime Okano in
Current site
Google Scholar
PubMed
Search for other papers by Hajime Okano in
Current site
Google Scholar
PubMed
Aristeu Vieira da Silva
Aristeu Vieira da Silva
Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Universidad Estadual Paulista, Botucatu, Sao Paulo, Brazil; Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan; Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil; Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil; Parasitology Research Group, Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Bahia, Brazil
Search for other papers by Aristeu Vieira da Silva in
Current site
Google Scholar
PubMed
Search for other papers by Aristeu Vieira da Silva in
Current site
Google Scholar
PubMed
Virulence of Rhodococcus equi strains from 20 humans in Brazil was investigated by using a polymerase chain reaction to characterize isolates as virulent (VapA), intermediately virulent (VapB), and avirulent. Nine isolates were obtained from human immunodeficiency virus (HIV)–positive patients, six from HIV-negative patients, and five from patients of unknown status. Five isolates were VapB positive, four were VapA positive, and eleven were avirulent. Among the nine isolates from HIV-positive patients, five contained VapB plasmids and two contained VapA plasmids. Five VapB-positive isolates had the type 8 virulence plasmid. Eleven of the patients had a history of contact with livestock and/or a farm environment, and none had contact with pigs.
Author Notes
Financial support: This study was supported by Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil (grant no. 06/50406–0).
Authors' addresses: Márcio Garcia Ribeiro, Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Higiene Veterinária e Saúde Pública, CP 560, CEP 18618-970, Botucatu, Sao Paulo, Brazil, E-mail: mgribeiro@fmvz.unesp.br. Shinji Takai, Ryoko Ohno, and Hajime Okano, Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada-Shi, Aomori, 034-8628, Japan, E-mail: takai@vmas.kitasato-u.ac.jp. Agueda Castagna de Vargas, Centro de Ciências Rurais, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, CEP 97105-900, Santa Maria, Rio Grande do Sul, Brazil, E-mail: agueda.vargas@gmail.com. Ana Luiza Mattos-Guaraldi and Thereza Cristina Ferreira Camello, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, 3° Andar, CEP 20.551-030, Rio de Janeiro, Brazil, E-mails: aguaraldi@gmail.com and camello@unisys.com.br. Aristeu Vieira da Silva, Departamento de Ciências Biológicas, Universidade de Feira de Santana, Rodovia Transnordestina, s/n, CEP 44.036-900, Feira de Santana, Bahia, Brazil, E-mail: aristeuvsilva@gmail.com.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Prescott JF, 1991. Rhodococcus equi: an animal and human pathogen. Clin Microbiol Rev 4: 20–34.
-
2.
Takai S, Tharavichitkul P, Takarn P, Khantawa B, Tamura M, Tsukamoto A, Takayama S, Yamatoda N, Kimura A, Sasaki Y, Kakuda T, Tsubaki S, Maneekarn N, Sirisanthana T, Kirikae T, 2003. Molecular epidemiology of Rhodococcus equi of intermediate virulence isolated from patients with and without acquired immune deficiency syndrome in Ching Mai, Thailand. J Infect Dis 188: 1717–1723.
-
3.
Weinstock DM, Brown AE, 2002. Rhodococcus equi: an emerging pathogen. Clin Infect Dis 34: 1379–1385.
-
4.
Takai S, 1997. Epidemiology of Rhodococcus equi infections: a review. Vet Microbiol 56: 167–176.
-
5.
Verville DT, Huicke MM, Greenfield RA, Fine DP, Kuhls TL, Slater LN, 1994. Rhodococcus equi infections of humans: 12 cases and literature review. Medicine 73: 119–132.
-
6.
Ribeiro MG, Seki I, Yasuoka K, Kakuda T, Sasaki Y, Tsubaki S, Takai S, 2005. Molecular epidemiology of virulent Rhodococcus equi from foals in Brazil: virulence plasmids of 85-kb type I, 87-kb type I, and a new variant, 87-kb type III. Comp Immunol Microbiol Infect Dis 28: 53–61.
-
7.
Takai S, Fukunga N, Ochiai S, Imai Y, Sasaki Y, Tsubaki S, Sekizaki T, 1996. Identification of intermediately virulent Rhodococcus equi isolates from pigs. J Clin Microbiol 34: 1034–1037.
-
8.
Quinn PJ, Carter ME, Markey B, Carter GR, 1994. Clinical Veterinary Microbiology. London: Wolfe, 137–143.
-
9.
Takai S, Ikeda T, Sasaki Y, Watanabe Y, Ozawa T, Tsubaki S, Sekizaki T, 1995. Identification of virulent Rhodococcus equi by amplification of gene coding for 15–17-kDa antigens. J Clin Microbiol 33: 1624–1627.
-
10.
Makrai L, Kobayashi A, Matsuoka M, Sasaki Y, Kakuda T, Dénes B, Hajtós I, Révész I, Jánosi K, Fodor L, Varga J, Takai S, 2008. Isolation and characterization of Rhodococcus equi from submaxillary lymph nodes of wild boars (Sus scrofa). Vet Microbiol 131: 318–323.
-
11.
Takai S, Sasaki Y, Ikeda T, Uchida Y, Tsubaki S, Sekizaki T, 1994. Virulence of Rhodococcus equi isolates from patients with and without AIDS. J Clin Microbiol 32: 457–460.
-
12.
Makrai L, Takai S, Tamura M, Tsukamoto A, Sekimoto R, Sasaki Y, Kakuda T, Tsubaki S, Varga J, Fodor L, Solymosi N, Major A, 2002. Characterization of virulence plasmids in Rhodococcus equi isolates from foals, pigs, humans and soil in Hungary. Vet Microbiol 88: 377–384.
-
13.
Ministério da Saúde Brazil, 2007. Programa Nacional de DST/AIDS. Brasilia: Secretaria de Vigilância em Saúde. Boletim Epidemiológico DST/AIDS.
-
14.
Silva P, Miyata M, Sato DN, Santos AC, Mendes NH, Leite CQ, 2010. Rhodococcus equi isolation from sputum of patients with suspected tuberculosis. Mem Inst Oswaldo Cruz 105: 199–202.
-
15.
Ribeiro MG, Takai S, Guazzelli A, Lara GH, Silva AV, Fernandes MC, Condas LAZ, Siqueira AK, Salerno T, 2010. Virulence genes and plasmid profiles in Rhodococcus equi isolates from domestic pig and wild boars (Sus scrofa) in Brazil. Res Vet Sci Oct 25 [Epub ahead of print].
-
16.
Costa MM, Machado SA, Krewer CC, Fighera RA, Ilha MR, Graça DL, Vargas AP, Mattos-Guaraldi AL, 2006. Pathogenecity of Rhodococcus equi isolates from human, horse clinical and environment in immunodeficient mice. Pesqui Vet Bras 26: 167–170.
-
17.
Napoleão F, Damasco PV, Camello TC, Vale MD, Andrade AF, Hirata R Jr, Mattos-Guaraldi AL, 2005. Pyogenic liver abscess due to Rhodococcus equi in an immunocompetent host. J Clin Microbiol 43: 1002–1004.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1152 | 1089 | 22 |
| Full Text Views | 1325 | 12 | 0 |
| PDF Downloads | 62 | 13 | 0 |