Abdominal Computed Tomography Scan: A Useful Diagnosis Tool for Early and Delayed Splenic Complications in Malaria

Patrick Imbert
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Cécile Ficko
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Pierre Buffet
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Christophe Rapp
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Author Notes

  • 1.

    Kim EM, Cho HJ, Cho CR, Kwak YG, Kim MY, Cho YK, 2010. Abdominal computed tomography findings of malaria infection with Plasmodium vivax. Am J Trop Med Hyg 83: 12021205.

  • 2.

    Imbert P, Rapp C, Buffet P, 2009. Pathological rupture of the spleen in malaria: analysis of 55 cases (1958–2008). Travel Med Infect Dis 7: 147159.

  • 3.

    McKenzie FE, Jeffery GM, Collins WE, 2002. Plasmodium vivax blood-stage dynamics. J Parasitol 88: 521535.

  • 4.

    Urban BC, Hien TT, Day NP, Phu NH, Roberts R, Pongponratn E, Jones M, Mai NT, Bethell D, Turner GD, Ferguson D, White NJ, Roberts D, 2005. Fatal Plasmodium falciparum malaria causes specific patterns of splenic architectural disorganization. Infect Immun 73: 19861994.

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  • 5.

    Buffet PA, Safeukui I, Deplaine G, Brousse V, Prendki V, Thellier M, Turner G, Mercereau-Puijalon O, 2011. The pathogenesis of Plasmodium falciparum malaria in humans: insights from spleen physiology. Blood 117: 381392.

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  • 6.

    Deplaine G, Safeukui I, Jeddi F, Lacoste F, Brousse V, Perrot S, Biligui S, Guillotte M, Guitton C, Dokmak S, Aussilhou B, Sauvanet A, Couvelard A, Paye F, Thellier M, Mazier D, Milon G, Mohandas N, Mercereau-Puijalon O, David PH, Buffet PA, 2011. The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro. Blood 117: e8895.

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  • 7.

    Anstey NM, Russell B, Yeo TW, Price RN, 2009. The pathophysiology of vivax malaria. Trends Parasitol 25: 220227.

  • 8.

    Imbert P, Rapp C, Ficko C, Buffet P, 2010. Left upper quadrant abdominal pain in malaria: suspect pathological splenic rupture first. Trans R Trop Med Hyg 104: 628629.

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