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Tuberculosis-Associated Chronic Kidney Disease

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  • Division of Nephrology, Department of Internal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil; School of Medicine, University of Fortaleza, Fortaleza, Ceará, Brazil
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Extrapulmonary tuberculosis (TB) account for approximately 15–20% of TB cases in immunocompetent patients. The genitourinary system is the third most commonly affected site. We report the case of a 20-year-old man admitted with fever, chills, dry cough, right flank pain, and oliguria who developed renal function loss. The pyelogram evidenced silence of the right kidney, and the abdominal and pelvic magnetic resonance showed significant dilation of the right pyelocaliceal system and proximal ureter. Biopsies of renal cortex and retroperitoneal lymph nodes showed caseous granuloma consistent with TB. Treatment was started with rifampicin, isoniazid, pyrazinamide, and ethambutol, and the patient presented a favorable outcome but with non-dialytic chronic kidney disease. This case illustrates a case of chronic kidney disease secondary to TB in a young, otherwise healthy man.

Author Notes

*Address correspondence to Elizabeth De Francesco Daher, Rua Vicente Linhares, 1198 Fortaleza, CE, CEP 60270-135, Brazil. E-mails: ef.daher@uol.com.br or jobson.lopes@hotmail.com

Authors' addresses: Jobson Lopes de Oliveira and Elizabeth De Francesco Daher, Division of Nephrology, Department of Internal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil, E-mails: jobson.lopes@hotmail.com and ef.daher@uol.com.br. Geraldo Bezerra da Silva Junior, Division of Nephrology, Department of Internal Medicine, Federal University of Ceará and School of Medicine, University of Fortaleza, Fortaleza, Ceará, Brazil, E-mail: geraldobezerrajr@yahoo.com.br.

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