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Incidence and Risk Factors of Hookworm Infection in a Rural Community of Central Thailand

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  • Department of Parasitology, Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, Thailand; School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia

A cohort study to identify incidence and risk factors of hookworm infection was conducted in a rural community, central Thailand from November 2005 to February 2007. Stool specimens were examined for hookworm eggs using wet preparation, Kato thick smear, and water-ethyl acetate sedimentation technique. The incidence rate of hookworm infection was 7.5/100 person-years. The independent risk factors for acquiring hookworm infection were barefoot walking (incidence rate ratio [IRR] = 4.2, 95% confidence interval [CI] = 1.2–14.5) and raising buffaloes around the house (IRR = 4.8, 95% CI = 1.9–11.8). Sequencing of internal transcribed spacer 1 (ITS1)-5.8S-ITS2 region of the ribosomal RNA gene were performed for identifying species of hookworm. Necator americanus was the most common hookworm identified in this population. Ancylostoma duodenale and A. ceylanicum were also detected. Our data suggest transmission of both human and animal hookworms in this community. Thus, prevention and control strategies of hookworm infection should cover both human and animal infection.

Author Notes

*Address correspondence to Saovanee Leelayoova, Department of Parasitology, Phramongkutklao College of Medicine, Ratchawithi Rd., Bangkok 10400, Thailand. E-mail: s_leelayoova@scientist.com

Financial support: This work was financially supported by Phramongkutklao College of Medicine, Royal Thai Army, Thailand.

Authors' addresses: Vittaya Jiraanankul, Wongwarit Aphijirawat, Mathirut Mungthin, Rommanee Khositnithikul, Phunlerd Piyaraj, Tawee Naaglor, Paanjit Taamasri, and Saovanee Leelayoova, Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand, E-mail: s_leelayoova@scientist.com. Ram Rangsin, Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, Thailand. Rebecca J. Traub, School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia.

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