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Serum tumor necrosis factor-α (TNF-α) was evaluated in Vibrio vulnificus-infected patients at admission. The median TNF-α concentration in the non-survivor group was determined to be 261.0 pg/mL, in contrast to 69.5 pg/mL in the survivor group (P = 0.001). Hence, serum TNF-α concentration may potentially be an early predictor of the mortality in patients with Vibrio septicemia.
Authors' addresses: Jun-Young Lee, Department of Orthopaedic Surgery, Chosun University College of Medicine, Dong-Gu, Gwangju, Republic of Korea, E-mail: leejy88@chosun.ac.kr. Dong-Min Kim, Na-Ra Yun, and Ganesh Prasad Neupane, Department of Internal Medicine, Chosun University College of Medicine, Dong-Gu, Gwangju, Republic of Korea, E-mails: drongkim@chosun.ac.kr, shinenara@gmail.com, and neupaneganesh@yahoo.com. Sook-In Jung, Kyung-Hwa Park, and Hee Chang Jang, Department of Infectious Diseases, Chonnam National University Hospital, Dong-gu, Gwangju, Republic of Korea, E-mails: sijung@jnu.ac.kr, medkid@dreamwiz.com, and haroc153@naver.com. Chang Seop Lee, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Geumam-dong, Jeonju, Republic of Korea, E-mail: lcsmd@jbnu.ac.kr. Sun Hee Lee, Department of Internal Medicine, College of Medicine, Pusan National University, Pusan, South Korea, E-mail: mdssampak@yahoo.co.kr.