• 1.

    World Health Organization, 2009. Dengue Guidelines for Diagnosis, Treatment, Prevention and Control. Document WHO/HTM/NTD/DEN/2009.1. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 2.

    World Health Organization, 2006. Report of the Scientific Working Group on Dengue. Document WHO/TDR/SWG/08. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 3.

    Erlanger TE, Keiser J, Utzinger J, 2008. Effect of dengue vector control interventions on entomological parameters in developing countries: a systematic review and meta-analysis. Med Vet Entomol 22: 203221.

    • Search Google Scholar
    • Export Citation
  • 4.

    Rawlins SC, 1998. Spatial distribution of insecticide resistance in Caribbean populations of Aedes aegypti and its significance. Rev Panam Salud Publica 4: 243251.

    • Search Google Scholar
    • Export Citation
  • 5.

    Rodriguez MM, Bisset J, Ruiz M, Soca A, 2002. Cross-resistance to pyrethroid and organophosphorus insecticides induced by selection with temephos in Aedes aegypti (Diptera: Culicidae) from Cuba. J Med Entomol 39: 882888.

    • Search Google Scholar
    • Export Citation
  • 6.

    Thavara U, Tawatsin A, Kong-Ngamsuk W, Mulla MS, 2004. Efficacy and longevity of a new formulation of temephos larvicide tested in village-scale trials against larval Aedes aegypti in water-storage containers. J Am Mosq Control Assoc 20: 176182.

    • Search Google Scholar
    • Export Citation
  • 7.

    Brengues C, Hawkes NJ, Chandre F, McCarroll L, Duchon S, Guillet P, Manguin S, Morgan JC, Hemingway J, 2003. Pyrethroid and DDT cross-resistance in Aedes aegypti is correlated with novel mutations in the voltage-gated sodium channel gene. Med Vet Entomol 17: 8794.

    • Search Google Scholar
    • Export Citation
  • 8.

    Strode C, Wondji CS, David JP, Hawkes NJ, Lumjuan N, Nelson DR, Drane DR, Karunaratne SH, Hemingway J, Black WC IV, Ranson H, 2008. Genomic analysis of detoxification genes in the mosquito Aedes aegypti. Insect Biochem Mol Biol 38: 113123.

    • Search Google Scholar
    • Export Citation
  • 9.

    Marcombe S, Poupardin R, Darriet F, Reynaud S, Bonnet J, Strode C, Brengues C, Yebakima A, Ranson H, Corbel V, David JP, 2009. Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies). BMC Genomics 10: 494.

    • Search Google Scholar
    • Export Citation
  • 10.

    Marcombe S, Carron A, Darriet F, Etienne M, Agnew P, Tolosa M, Yp-Tcha MM, Lagneau C, Yebakima A, Corbel V, 2009. Reduced efficacy of pyrethroid space sprays for dengue control in an area of Martinique with pyrethroid resistance. Am J Trop Med Hyg 80: 745751.

    • Search Google Scholar
    • Export Citation
  • 11.

    Jirakanjanakit N, Saengtharatip S, Rongnoparut P, Duchon S, Bellec C, Yoksan S, 2007. Trend of temephos resistance in Aedes (Stegomyia) mosquitoes in Thailand during 2003–2005. Environ Entomol 36: 506511.

    • Search Google Scholar
    • Export Citation
  • 12.

    Martins AJ, Belinato TA, Lima JB, Valle D, 2008. Chitin synthesis inhibitor effect on Aedes aegypti populations susceptible and resistant to organophosphate temephos. Pest Manag Sci 64: 676680.

    • Search Google Scholar
    • Export Citation
  • 13.

    Lacey LA, 2007. Bacillus thuringiensis serovariety israelensis and Bacillus sphaericus for mosquito control. J Am Mosq Control Assoc 23: 133163.

    • Search Google Scholar
    • Export Citation
  • 14.

    Lima JB, de Melo NV, Valle D, 2005. Residual effect of two Bacillus thuringiensis var. israelensis products assayed against Aedes aegypti (Diptera: Culicidae) in laboratory and outdoors at Rio de Janeiro, Brazil. Rev Inst Med Trop Sao Paulo 47: 125130.

    • Search Google Scholar
    • Export Citation
  • 15.

    World Health Organization, 2004. Report of the Seventh WHOPES Working Goup Meeting. WHO/HQ, Geneva, December 2–4, 2003, Review of Vectobac WG, Permanet, Gokilath-S 5EC. Document WHO/CDS/WHOPES/2004.8. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 16.

    World Health Organization, 2006. Report of the Ninth WHOPES Working Group Meeting. WHO/HQ, Geneva, December 5–9, 2005. Review of Dimilin GR and DT, Vectobac DT, Aqua K-Othrine, Aqua Reslin Super. Document WHO/CDS/NTD/WHOPES/2006.2. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 17.

    Corriveau R, Philippon B, Yebakima A, 2003. La Dengue dans les Départements Français d'Amérique. Comment Optimiser la Lutte Contre Cette Maladie? IRD Édition. Paris: Expertise Collégiale.

    • Search Google Scholar
    • Export Citation
  • 18.

    Bill and Melinda Gates Foundation, 2007. Market Assessment for Public Health Pesticide Products: A Report by the Bill and Melinda Gates Foundation and the Boston Consulting Group. Seattle, WA: Bill and Melinda Gates Foundation.

    • Search Google Scholar
    • Export Citation
  • 19.

    Matsumura F, 2010. Studies on the action mechanism of benzoylurea insecticides to inhibit the process of chitin synthesis in insects: a review on the ststus of research activities in the past, the present and the future prospects. Pesticide Biochenistry and Physiology 97: 133139.

    • Search Google Scholar
    • Export Citation
  • 20.

    Thavara U, Tawatsin A, Chansang C, Asavadachanukorn P, Zaim M, Mulla MS, 2007. Simulated field evaluation of the efficacy of two formulations of diflubenzuron, a chitin synthesis inhibitor against larvae of Aedes aegypti (L.) (Diptera: Culicidae) in water-storage containers. Southeast Asian J Trop Med Public Health 38: 269275.

    • Search Google Scholar
    • Export Citation
  • 21.

    Copping LG, Menn JJ, 2000. Biopesticides: a review of their action, application and efficacy. Pest Manag Sci 56: 651676.

  • 22.

    Salgado VL, 1997. The modes of action of spinosad and other insect control products. Down Earth 52: 3543

  • 23.

    Darriet F, Corbel V, 2006. Laboratory evaluation of pyriproxyfen and spinosad, alone and in combination, against Aedes aegypti larvae. J Med Entomol 43: 11901194.

    • Search Google Scholar
    • Export Citation
  • 24.

    Dhadialla TS, Carlson GR, Le DP, 1998. New insecticides with ecdysteroidal and juvenile hormone activity. Annu Rev Entomol 43: 545569.

  • 25.

    Paul A, Harrington LC, Scott JG, 2006. Evaluation of novel insecticides for control of dengue vector Aedes aegypti (Diptera: Culicidae). J Med Entomol 43: 5560.

    • Search Google Scholar
    • Export Citation
  • 26.

    World Health Organization, 2008. Diflubenzuron in Drinking-Water: Use for Vector Control in Drinking-water Sources and Containers. Document WHO/HSE/AMR/08.03/6. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 27.

    World Health Organization, 2008. Pyriproxyfen in Drinking-Water: Use for Vector Control in Drinking-water Sources and Containers. Document WHO/HSE/AMR/08.03/9. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 28.

    World Health Organization, 2010. Spinosad DT in Drinking-Water: Use for Vector Control in Drinking-water Sources and Containers. Document WHO/HSE/WSH/10.01/12. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 29.

    Saavedra-Rodriguez K, Urdaneta-Marquez L, Rajatileka S, Moulton M, Flores AE, Fernandez-Salas I, Bisset J, Rodriguez M, McCall PJ, Donnelly MJ, Ranson H, Hemingway J, Black WC IV, 2007. A mutation in the voltage-gated sodium channel gene associated with pyrethroid resistance in Latin American Aedes aegypti. Insect Mol Biol 16: 785798.

    • Search Google Scholar
    • Export Citation
  • 30.

    World Health Organization, 2005. Guidelines for Laboratory and Field Testing of Mosquito Larvicides. Document WHO/CDS/WHOPES/GCDPP/13. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 31.

    Yebakima A, 1991. Recherche sur Aedes aegypti et Culex pipiens en Martinique. Ecologie Larvaire, Résistance aux Insecticides, Application à la Lutte. Thèse de Doctorat d'Etat es Sciences. Montpellier, France: Université Montpellier II.

    • Search Google Scholar
    • Export Citation
  • 32.

    World Health Organization, 2006. Pesticides and their Application for the Control of Vectors and Pests of Public Health Importance. Sixth edition. WHO/CDS/NTD/WHOPES/GCDPP/2006.1. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 33.

    World Health Organization, 2008. Report of the Eleventh WHOPES Working Group Meeting WHO/HQ. Geneva, December 10–13, 2007. Review of: Spinosad 7.48% DT, Netprotect, Duranet, Dawaplus, Icon Maxx. Document WHO/HTM/NTD/WHOPES/2008.1. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 34.

    Abbott W, 1925. A method of computing the effectiveness of an insecticide. J Econ Entomol 18: 265267.

  • 35.

    Finney D, 1971. Probit Analysis. Cambridge, UK: Cambridge University Press.

  • 36.

    Raymond M, Prato G, Ratsira D, 1997. Probit and Logit Analysis Program version 2.0. Montpellier, France: Praxème R&D.

  • 37.

    World Health Organization, 2009. Bacillus thuringiensis israelensis (Bti) in Drinking-Water, Background Document for Development of WHO Guidelines for Drinking-Water Quality. Document WHO Revised Fourth Edition Bacillus thuringiensis_Bti_July272009_2. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 38.

    World Health Organization, 2001. Report of the 4th WHOPES Working Group Meeting – IR3535, KBR3023, (RS)-Methoprene 20%EC, Pyriproxyfen 0.5%GR and Lambda-Cyhalothrin 2.5%CS. December 4–5, 2000, Geneva, 2001. Document WHO/CDS/WHOPES/2001.2. Geneva: World Health Organization.

    • Search Google Scholar
    • Export Citation
  • 39.

    Vythilingam I, Luz BM, Hanni R, Beng TS, Huat TC, 2005. Laboratory and field evaluation of the insect growth regulator pyriproxyfen (Sumilarv 0.5G) against dengue vectors. J Am Mosq Control Assoc 21: 296300.

    • Search Google Scholar
    • Export Citation
  • 40.

    Becker N, Petric D, Zgomba M, Boase C, Dahl C, Lane J, Kaiser A, 2003. Mosquitoes and Their Control. New York: Kluwer Academic/Plenum Publishers.

  • 41.

    Sihuincha M, Zamora-Perea E, Orellana-Rios W, Stancil JD, Lopez-Sifuentes V, Vidal-Ore C, Devine GJ, 2005. Potential use of pyriproxyfen for control of Aedes aegypti (Diptera: Culicidae) in Iquitos, Peru. J Med Entomol 42: 620630.

    • Search Google Scholar
    • Export Citation
  • 42.

    Tilquin M, Paris M, Reynaud S, Despres L, Ravanel P, Geremia RA, Gury J, 2008. Long lasting persistence of Bacillus thuringiensis Subsp. israelensis (Bti) in mosquito natural habitats. PLoS ONE 3: e3432.

    • Search Google Scholar
    • Export Citation
  • 43.

    Bret BL, Larson LL, Schoonover JR, Sparks TC, Thompson GD, 1997. Biological properties of Spinosad. Down to Earth 52: 613.

  • 44.

    Darriet F, Duchon S, Hougard JM, 2005. Spinosad: a new larvicide against insecticide-resistant mosquito larvae. J Am Mosq Control Assoc 21: 495296.

    • Search Google Scholar
    • Export Citation
  • 45.

    Macoris-Andrighetti MT, Cerone F, Rigueti M, Galvani KC, de Lourdes, da Graça M, 2008. Effect of pyriproxyfen in Aedes aegypti populations with different levels of susceptibility to the organophosphate temephos. Dengue Bull 32: 186198.

    • Search Google Scholar
    • Export Citation
  • 46.

    Kasai S, Shono T, Komagata O, Tsuda Y, Kobayashi M, Motoki M, Kashima I, Tanikawa T, Yoshida M, Tanaka I, Shinjo G, Hashimoto T, Ishikawa T, Takahashi T, Higa Y, Tomita T, 2007. Insecticide resistance in potential vector mosquitoes for West Nile virus in Japan. J Med Entomol 44: 822829.

    • Search Google Scholar
    • Export Citation
  • 47.

    Melo-Santos MA, Varjal-Melo JJ, Araujo AP, Gomes TC, Paiva MH, Regis LN, Furtado AF, Magalhaes T, Macoris ML, Andrighetti MT, Ayres CF, 2010. Resistance to the organophosphate temephos: mechanisms, evolution and reversion in an Aedes aegypti laboratory strain from Brazil. Acta Trop 113: 180189.

    • Search Google Scholar
    • Export Citation

 

 

 

 

Field Efficacy of New Larvicide Products for Control of Multi-Resistant Aedes aegypti Populations in Martinique (French West Indies)

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  • Laboratoire de Lutte Contre les Insectes Nuisibles, Génétique et Evolution des Maladies Infectieuses, Centre National de la Recherche Scientifique Institut de Recherche pour le Développement, Montpellier, France; Centre de Démoustication, Conseil Général de la Martinique, Martinique; Institut de Recherche pour le Développement, Centre de Recherche Entomologique de Cotonou, Cotonou, Benin

World-wide dengue vector control is hampered by the spread of insecticide resistance in Aedes aegypti. We report the resistance status of a wild Ae. aegypti population from Martinique (Vauclin) to conventional larvicides (Bacillus thuringiensis var israeliensis [Bti] and temephos) and potential alternatives (spinosad, diflubenzuron, and pyriproxyfen). The efficacy and residual activity of these insecticides were evaluated under simulated and field conditions. The Vauclin strain exhibited a high level of resistance to temephos, a tolerance to insect growth regulators, and full susceptibility to spinosad and Bti. In simulated trials, pyriproxyfen and Bti showed long residual activities in permanent breeding containers (28 and 37 weeks), whereas under field conditions they failed to curtail Ae. aegypti populations after four weeks. Conversely, diflubenzuron and spinosad showed a residual efficacy of 16 weeks, suggesting that these chemicals may be promising alternatives to Bti and temephos for controlling insecticide-resistant Ae. aegypti populations.

Author Notes

*Address correspondence to Sébastien Marcombe, Laboratoire de Lutte Contre les Insectes Nuisibles, Institut de Recherche pour le Développement, 911 Avenue Agropolis, BP 64501, 34394 Montpellier Cedex 5, France. E-mail: sebastien.marcombe@ird.fr

Financial support: This study was supported by the French Agency for Environmental Health and Safety and the Institut de Recherche pour le Developpement.

Authors' addresses: Sébastien Marcombe and Frédéric Darriet, Laboratoire de Lutte Contre les Insectes Nuisibles, Institut de Recherche pour le Développement, Montpellier Cedex 5, France, E-mails: sebastien.marcombe@ird.fr and frederic.darriet@ird.fr. Philip Agnew, Génétique et Evolution des Maladies Infectieuses, Centre National de la Recherche Scientifique, Unité de Mixte Recherche, 2724, Institut de Recherche pour le Développement, Montpellier Cedex 5, France, E-mail: philip.agnew@ird.fr. Manuel Etienne, Marie-Michelle Yp-Tcha, and André Yébakima, Centre de la Démoustication, Fort de France, Martinique, E-mails: etienne.manuel@cg972.fr, yp-tcha@cg972.fr, and Yebakima@cg972.fr. Vincent Corbel, Institut de Recherche pour le Développement, Centre de Recherche Entomologique de Cotonou, Cotonou, Benin, E-mail: vincent.corbel@ird.fr.

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