Fatal Staphylococcal Infection following Classic Dengue Fever

Stanley Almeida Araújo Program of Infectious Diseases and Tropical Medicine, Medical School, Federal University of Minas Gerais, Brazil; Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil; Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil; Evandro Chagas Institute, Belém do Pará, Brazil

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Daniel Ribeiro Moreira Program of Infectious Diseases and Tropical Medicine, Medical School, Federal University of Minas Gerais, Brazil; Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil; Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil; Evandro Chagas Institute, Belém do Pará, Brazil

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Juliana Marcia Ribeiro Veloso Program of Infectious Diseases and Tropical Medicine, Medical School, Federal University of Minas Gerais, Brazil; Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil; Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil; Evandro Chagas Institute, Belém do Pará, Brazil

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Jenaine Oliveira Silva Program of Infectious Diseases and Tropical Medicine, Medical School, Federal University of Minas Gerais, Brazil; Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil; Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil; Evandro Chagas Institute, Belém do Pará, Brazil

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Vera Lucia Souza Reis Barros Program of Infectious Diseases and Tropical Medicine, Medical School, Federal University of Minas Gerais, Brazil; Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil; Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil; Evandro Chagas Institute, Belém do Pará, Brazil

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Vandack Nobre Program of Infectious Diseases and Tropical Medicine, Medical School, Federal University of Minas Gerais, Brazil; Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil; Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil; Evandro Chagas Institute, Belém do Pará, Brazil

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Dengue represents an important public health issue in many tropical areas, leading to high morbidity and the employment of substantial health resources. Even though the number of fatalities related to dengue is unknown, several reports warn about the potential occurrence of severe infections and even death. The clinical spectrum of dengue is highly variable, ranging from a mild flu-like syndrome to severe disease, with shock and hemorrhage. The occurrence of bacterial superinfection, or coinfection, in patients with dengue has been noted by some authors, but the available information comes from anecdotic reports. In this study, we show the clinical and anatomopathological data of a patient infected with dengue, who subsequently died of acute multi-organic failure related to Staphylococcus aureus infection. The autopsy revealed a severe disseminated staphylococcal disease and confirmed dengue infection.

Author Notes

*Address correspondence to Stanley Almeida Araújo, Rua Carangola n 82, apto 604, Bairro Santo Antônio, Belo Horizonte, Minas Gerais CEP: 30330-240, Brazil. E-mail: stanleyaa@gmail.com

Authors' addresses: Stanley Almeida Araújo, Program of Infectious Diseases and Tropical Medicine and Department of Pathology, Medical School, Federal University of Minas, Gerais, Brazil, E-mail: stanleyaa@gmail.com. Daniel Ribeiro Moreira, Department of Pathology, Medical School, Federal University of Minas Gerais, Brazil, E-mail: moreira_daniel@hotmail.com. Juliana Marcia Ribeiro Veloso and Jenaine Oliveira Silva, Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil, E-mails: ju.veloso@gmail.com and jenaineoliveira@yahoo.com.br. Vera Lucia Souza Reis Barros, Evandro Chagas Institute, Belém do Pará, Brazil, E-mail: verabarros@iec.pa.gov.br. Vandack Nobre, Program of Infectious Diseases and Tropical Medicine and Department of Internal Medicine, Medical School, Federal University of Minas Gerais, Brazil, E-mail: vandack@gmail.com.

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