Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Ministry of Health, 2005. Health Sector Strategic Plan. (HSDP III). Addis Ababa, Ethiopia: Ministry of Health.
-
2.
White GB, Tesfaye F, Boreham PF, Lemma G, 1980. Malaria vector capacity of Anopheles arabiensis and An. quadriannulatus in Ethiopia: chromosomal interpretation after 6 years storage of field preparation. Trans R Soc Trop Med Hyg 74: 683–684.
-
3.
Abose T, Yeebiyo Y, Olana D, Alamirew D, Beyene YA, Regassa L, Mengesha A, 1998. Re-orientation and definition of the role of malaria vector control in Ethiopia. WHO/Mal/1998. Geneva, Switzerland: World Health Organization, 19.
-
4.
Balkew M, Gebre-Michael T, Hailu A, 2003. Insecticide susceptibility level of Anopheles arabiensis in two agro-development localities in Eastern Ethiopia. Parassitologia 45: 1–3.
-
5.
Martinez-Torres D, Chandre F, Williamson MS, Darriet F, Berge JB, Devonshire AL, Guillet P, Pasteur N, Pauron D, 1998. Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s.s. Insect Mol Biol 7: 179–184.
-
6.
Ranson H, Jenson B, Vulule JM, Wang X, Hemingway J, Collins FH, 2000. Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol 9: 491–497.
-
7.
Fanello C, Petrarca V, della Torre A, Santolamazaa F, Dolo G, Coulibaly M, Alloueche A, Curtis CF, Toure YT, Coluzzi M, 2003. The pyrethroid knock-down resistance gene in the Anopheles gambiae complex in Mali and further indication of incipient speciation within An. gambiae s.s. Insect Mol Biol 12: 241–245.
-
8.
Yawson AE, McCall PJ, Wilson MD, Donnelly MJ, 2004. Species abundance and insecticide resistance of Anopheles gambiae in selected areas of Ghana and Burkina Faso. Med Vet Entomol 18: 372–377.
-
9.
Stump AD, Atieli FK, Vulule JM, Besansky NJ, 2004. Dynamics of the pyrethroid knockdown resistance allele in western Kenyan populations of Anopheles gambiae in response to insecticide-treated bed net trials. Am J Trop Med Hyg 70: 591–596.
-
10.
Pinto J, Lynd A, Elissa N, Donnelly MJ, Costa G, Gentile A, Caccone A, Do Rosario VE, 2006. Co-occurrence of East and West African kdr mutations suggests high levels of resistance to pyrethroid insecticides in Anopheles gambiae from Libreville, Gabon. Med Vet Entomol 20: 27–32.
-
11.
Verhaeghen K, Bortel WV, Roelants P, Backeljau T, Coosemans M, 2006. Detection of the East and West African kdr mutation in Anopheles gambiae and Anopheles arabiensis from Uganda using a new assay based on FRET/Melt curve analysis. Malar J 5: 1.
-
12.
Kulkarni MA, Rowland M, Alifrangis M, Mosha FW, Matowo J, Malima R, Peter J, Kweka E, Lyimo I, Magesa S, Salanti A, Rau ME, Drakeley C, 2006. Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method. Malar J 5: 56.
-
13.
Yewhalaw D, Legesse W, Bortel WV, Gebre-Selassie S, Kloos H, Duchateau L, Speybroeck N, 2009. Malaria and water resource development: the case of Gilgel-Gibe hydroelectric dam in Ethiopia. Malar J 8: 21.
-
14.
World Health Organization, 1975. Manual on Practical Entomology in Malaria. Part II. Methods and Techniques. Geneva, Switzerland: World Health Organization.
-
15.
Gillies MT, Coetzee M, 1987. A Supplement to the Anophelinae of Africa South of the Sahara (Afrotropical Region). Johannesburg, South Africa: South African Institute for Medical Research, 55.
-
16.
Collins FH, Mendez MA, Rasmussen MO, Mehaffey PC, Besansky NJ, Finnerty V, 1987. A ribosomal RNA gene probe differentiates member species of the Anopheles gambiae complex. Am J Trop Med Hyg 37: 37–41.
-
17.
Hunt RH, Coetzee M, Fettene M, 1998. The Anopheles gambiae complex: a new species from Ethiopia. Trans R Soc Trop Med Hyg 92: 231–235.
-
18.
Raymond M, Rousset F, 1995. GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Hered 86: 248–249.
-
19.
World Health Organization, 1998. Test procedures for insecticide resistance monitoring in malaria vectors, bioefficacy and persistence of insecticides on treated surfaces. Report of the WHO informal consultation. WHO/CDS/CPC/MAL/98.12. Geneva, Switzerland: World Health Organization.
-
20.
Chouaibou M, Etag J, Brevault T, Nwane P, Hinzoumbe CK, Mimpfoundi R, Simard F, 2008. Dynamics of insecticide resistance in the malaria vector Anopheles gambiae s.l. from an area of extensive cotton cultivation in Northern Cameroon. Trop Med Int Health 13: 1–11.
-
21.
Diabate A, Baldet T, Chandre F, Dabire KR, Simard F, Ouedraogo JB, Guillet P, Hougard JM, 2004. First report of a kdr mutation in Anopheles arabiensis from Burkina Faso, West Africa. J Am Mosq Control Assoc 20: 195–196.
-
22.
Matambo TS, Abdalla H, Brooke BD, Koekemoer LL, Mnzava A, Hunt RH, Coetzee M, 2007. Insecticide resistance in the malarial mosquito Anopheles arabiensis and association with the kdr mutation. Med Vet Entomol 21: 97–102.
-
23.
Abdalla H, Matambo TS, Koekemoer LL, Hunt RH, Coetzee M, 2008. Insecticide susceptibility and vector status of natural populations of Anopheles arabiensis from Sudan. Trans R Soc Trop Med Hyg 102: 263–271.
-
24.
Chandre F, Darriet F, Manguin S, Brengues C, Carnevale P, Guillet P, 1999. Pyrethroid cross-resistance spectrum among populations of Anopheles gambiae s.s. from Cote d'Ivoire. J Am Mosq Control Assoc 15: 53–59.
-
25.
Ameneshewa B, 1995. The behavior and biology of Anopheles arabiensis in relation to the epidemiology and control of malaria in Ethiopia. PhD Thesis. Liverpool, UK: University of Liverpool.
-
26.
Hargreaves K, Hunt RH, Brooke BD, Mthembu J, Weeto MM, Awolola TS, Coetzee M, 2003. Anopheles arabiensis and An. quadriannulatus resistance to DDT in South Africa. Med Vet Entomol 17: 417–422.
-
27.
Brooke BD, 2008. Kdr: can a single mutation produce an entire insecticide resistance phenotype? Trans R Soc Trop Med Hyg 102: 524–525.
-
28.
Chandre F, Darriet F, Duchon S, Finot L, Manguin S, Carnevale P, Guillet P, 2000. Modification of pyrethroid effects associated with kdr mutation in Anopheles gambiae. Med Vet Entomol 14: 81–88.
-
29.
Henry MC, Assi SB, Rogier C, Dossou-Yoyo J, Chandre F, Guillet P, Carnevale P, 2005. Protective efficacy of lambda-cyhalothrin treated nets in Anopheles gambiae pyrethroid resistance areas of Cote d'Ivoire. Am J Trop Med Hyg 75: 859–864.
-
30.
Asidi AN, N'Guessan R, Koffi AA, Curtis CF, Hougard JM, Chandre F, Corbel V, Darriet F, Zaim R, Rowland MW, 2005. Experimental hut evaluation of bed nets treated with an organophosphate (chlorpyrifos-methyl) or a pyrethroid (lambda-cyhalothrin) alone and in combination against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes. Malar J 4: 25.
-
31.
N'Guessan R, Corbel V, Akogbeto M, Rowland M, 2007. Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria in pyrethroid resistance area, Benin. Emerg Infect Dis 13: 199–206.
-
32.
Williamson MS, Martinez-Torres D, Hick CA, Devonshire AL, 1996. Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides. Mol Gen Genet 252: 51–60.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 60 | 60 | 16 |
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First Evidence of High Knockdown Resistance Frequency in Anopheles arabiensis (Diptera: Culicidae) from Ethiopia
Delenasaw Yewhalaw
Delenasaw Yewhalaw
Department of Biology, Jimma University, Jimma, Ethiopia; Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium; Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
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Wim Van Bortel
Wim Van Bortel
Department of Biology, Jimma University, Jimma, Ethiopia; Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium; Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
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Leen Denis
Leen Denis
Department of Biology, Jimma University, Jimma, Ethiopia; Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium; Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
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Marc Coosemans
Marc Coosemans
Department of Biology, Jimma University, Jimma, Ethiopia; Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium; Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
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Luc Duchateau
Luc Duchateau
Department of Biology, Jimma University, Jimma, Ethiopia; Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium; Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
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Niko Speybroeck
Niko Speybroeck
Department of Biology, Jimma University, Jimma, Ethiopia; Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium; Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium; Institute of Health and Society, Université Catholique de Louvain, Brussels, Belgium
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The status of knockdown resistance (kdr) mutation was investigated in the major malaria vector Anopheles arabiensis Patton (Diptera: Culicidae) from Ethiopia. Among 240 mosquito samples from 15 villages of southwestern Ethiopia that were screened by allele-specific polymerase chain reaction for kdr mutations, the West African kdr mutation (L1014F) was detected in almost all specimens (98.5%), whereas the East African kdr mutation (L1014S) was absent. Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively. We report here the highest kdr allele frequency ever observed in An. arabiensis and its implications in malaria vector control in Ethiopia are discussed.
Author Notes
Financial support: The study received financial support from Flemish Interuniversity Council (VLIR-IUC).
Authors' addresses: Delenasaw Yewhalaw, Department of Biology, Jimma University, Jimma, Ethiopia, E-mail: delenasaw.yewhalaw@ju.edu.et. Wim Van Bortel, Leen Denis, and Marc Coosemans, Department of Parasitology, Institute of Tropical Medicine, Antwerpen, Belgium. Luc Duchateau, Department of Physiology and Biometrics, University of Ghent, Ghent, Belgium. Niko Speybroeck, Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium or Public Health School, Université Catholique de Louvian, Brussels, Belgium.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Ministry of Health, 2005. Health Sector Strategic Plan. (HSDP III). Addis Ababa, Ethiopia: Ministry of Health.
-
2.
White GB, Tesfaye F, Boreham PF, Lemma G, 1980. Malaria vector capacity of Anopheles arabiensis and An. quadriannulatus in Ethiopia: chromosomal interpretation after 6 years storage of field preparation. Trans R Soc Trop Med Hyg 74: 683–684.
-
3.
Abose T, Yeebiyo Y, Olana D, Alamirew D, Beyene YA, Regassa L, Mengesha A, 1998. Re-orientation and definition of the role of malaria vector control in Ethiopia. WHO/Mal/1998. Geneva, Switzerland: World Health Organization, 19.
-
4.
Balkew M, Gebre-Michael T, Hailu A, 2003. Insecticide susceptibility level of Anopheles arabiensis in two agro-development localities in Eastern Ethiopia. Parassitologia 45: 1–3.
-
5.
Martinez-Torres D, Chandre F, Williamson MS, Darriet F, Berge JB, Devonshire AL, Guillet P, Pasteur N, Pauron D, 1998. Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s.s. Insect Mol Biol 7: 179–184.
-
6.
Ranson H, Jenson B, Vulule JM, Wang X, Hemingway J, Collins FH, 2000. Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol 9: 491–497.
-
7.
Fanello C, Petrarca V, della Torre A, Santolamazaa F, Dolo G, Coulibaly M, Alloueche A, Curtis CF, Toure YT, Coluzzi M, 2003. The pyrethroid knock-down resistance gene in the Anopheles gambiae complex in Mali and further indication of incipient speciation within An. gambiae s.s. Insect Mol Biol 12: 241–245.
-
8.
Yawson AE, McCall PJ, Wilson MD, Donnelly MJ, 2004. Species abundance and insecticide resistance of Anopheles gambiae in selected areas of Ghana and Burkina Faso. Med Vet Entomol 18: 372–377.
-
9.
Stump AD, Atieli FK, Vulule JM, Besansky NJ, 2004. Dynamics of the pyrethroid knockdown resistance allele in western Kenyan populations of Anopheles gambiae in response to insecticide-treated bed net trials. Am J Trop Med Hyg 70: 591–596.
-
10.
Pinto J, Lynd A, Elissa N, Donnelly MJ, Costa G, Gentile A, Caccone A, Do Rosario VE, 2006. Co-occurrence of East and West African kdr mutations suggests high levels of resistance to pyrethroid insecticides in Anopheles gambiae from Libreville, Gabon. Med Vet Entomol 20: 27–32.
-
11.
Verhaeghen K, Bortel WV, Roelants P, Backeljau T, Coosemans M, 2006. Detection of the East and West African kdr mutation in Anopheles gambiae and Anopheles arabiensis from Uganda using a new assay based on FRET/Melt curve analysis. Malar J 5: 1.
-
12.
Kulkarni MA, Rowland M, Alifrangis M, Mosha FW, Matowo J, Malima R, Peter J, Kweka E, Lyimo I, Magesa S, Salanti A, Rau ME, Drakeley C, 2006. Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method. Malar J 5: 56.
-
13.
Yewhalaw D, Legesse W, Bortel WV, Gebre-Selassie S, Kloos H, Duchateau L, Speybroeck N, 2009. Malaria and water resource development: the case of Gilgel-Gibe hydroelectric dam in Ethiopia. Malar J 8: 21.
-
14.
World Health Organization, 1975. Manual on Practical Entomology in Malaria. Part II. Methods and Techniques. Geneva, Switzerland: World Health Organization.
-
15.
Gillies MT, Coetzee M, 1987. A Supplement to the Anophelinae of Africa South of the Sahara (Afrotropical Region). Johannesburg, South Africa: South African Institute for Medical Research, 55.
-
16.
Collins FH, Mendez MA, Rasmussen MO, Mehaffey PC, Besansky NJ, Finnerty V, 1987. A ribosomal RNA gene probe differentiates member species of the Anopheles gambiae complex. Am J Trop Med Hyg 37: 37–41.
-
17.
Hunt RH, Coetzee M, Fettene M, 1998. The Anopheles gambiae complex: a new species from Ethiopia. Trans R Soc Trop Med Hyg 92: 231–235.
-
18.
Raymond M, Rousset F, 1995. GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Hered 86: 248–249.
-
19.
World Health Organization, 1998. Test procedures for insecticide resistance monitoring in malaria vectors, bioefficacy and persistence of insecticides on treated surfaces. Report of the WHO informal consultation. WHO/CDS/CPC/MAL/98.12. Geneva, Switzerland: World Health Organization.
-
20.
Chouaibou M, Etag J, Brevault T, Nwane P, Hinzoumbe CK, Mimpfoundi R, Simard F, 2008. Dynamics of insecticide resistance in the malaria vector Anopheles gambiae s.l. from an area of extensive cotton cultivation in Northern Cameroon. Trop Med Int Health 13: 1–11.
-
21.
Diabate A, Baldet T, Chandre F, Dabire KR, Simard F, Ouedraogo JB, Guillet P, Hougard JM, 2004. First report of a kdr mutation in Anopheles arabiensis from Burkina Faso, West Africa. J Am Mosq Control Assoc 20: 195–196.
-
22.
Matambo TS, Abdalla H, Brooke BD, Koekemoer LL, Mnzava A, Hunt RH, Coetzee M, 2007. Insecticide resistance in the malarial mosquito Anopheles arabiensis and association with the kdr mutation. Med Vet Entomol 21: 97–102.
-
23.
Abdalla H, Matambo TS, Koekemoer LL, Hunt RH, Coetzee M, 2008. Insecticide susceptibility and vector status of natural populations of Anopheles arabiensis from Sudan. Trans R Soc Trop Med Hyg 102: 263–271.
-
24.
Chandre F, Darriet F, Manguin S, Brengues C, Carnevale P, Guillet P, 1999. Pyrethroid cross-resistance spectrum among populations of Anopheles gambiae s.s. from Cote d'Ivoire. J Am Mosq Control Assoc 15: 53–59.
-
25.
Ameneshewa B, 1995. The behavior and biology of Anopheles arabiensis in relation to the epidemiology and control of malaria in Ethiopia. PhD Thesis. Liverpool, UK: University of Liverpool.
-
26.
Hargreaves K, Hunt RH, Brooke BD, Mthembu J, Weeto MM, Awolola TS, Coetzee M, 2003. Anopheles arabiensis and An. quadriannulatus resistance to DDT in South Africa. Med Vet Entomol 17: 417–422.
-
27.
Brooke BD, 2008. Kdr: can a single mutation produce an entire insecticide resistance phenotype? Trans R Soc Trop Med Hyg 102: 524–525.
-
28.
Chandre F, Darriet F, Duchon S, Finot L, Manguin S, Carnevale P, Guillet P, 2000. Modification of pyrethroid effects associated with kdr mutation in Anopheles gambiae. Med Vet Entomol 14: 81–88.
-
29.
Henry MC, Assi SB, Rogier C, Dossou-Yoyo J, Chandre F, Guillet P, Carnevale P, 2005. Protective efficacy of lambda-cyhalothrin treated nets in Anopheles gambiae pyrethroid resistance areas of Cote d'Ivoire. Am J Trop Med Hyg 75: 859–864.
-
30.
Asidi AN, N'Guessan R, Koffi AA, Curtis CF, Hougard JM, Chandre F, Corbel V, Darriet F, Zaim R, Rowland MW, 2005. Experimental hut evaluation of bed nets treated with an organophosphate (chlorpyrifos-methyl) or a pyrethroid (lambda-cyhalothrin) alone and in combination against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes. Malar J 4: 25.
-
31.
N'Guessan R, Corbel V, Akogbeto M, Rowland M, 2007. Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria in pyrethroid resistance area, Benin. Emerg Infect Dis 13: 199–206.
-
32.
Williamson MS, Martinez-Torres D, Hick CA, Devonshire AL, 1996. Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides. Mol Gen Genet 252: 51–60.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 60 | 60 | 16 |
| Full Text Views | 426 | 115 | 4 |
| PDF Downloads | 110 | 12 | 0 |