• 1.

    Thomas L, 1971. The technology of medicine. N Engl J Med 285: 13661368.

  • 2.

    Thomas L, 1974. The Lives of a Cell. NewYork: Penguin Books.

  • 3.

    Grobusch MP, Egan A, Gosling RD, Newman RD, 2007. Intermittent preventive therapy for malaria: progress and future directions. Curr Opin Infect Dis 20: 613620.

    • Search Google Scholar
    • Export Citation
  • 4.

    Raman J, Little F, Roper C, Kleinschmidt I, Cassam Y, Maharaj R, Barnes KI, 2010. Five years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo province, southern Mozambique. Am J Trop Med Hyg 82: 788794.

    • Search Google Scholar
    • Export Citation
  • 5.

    Aponte JJ, Schellenberg D, Egan A, Breckenridge A, Carneiro I, Critchley J, Danquah I, Dodoo A, Kobbe R, Lell B, May J, Premji Z, Sanz S, Sevene E, Soulaymani-Becheikh R, Winstanley P, Adjei S, Anemana S, Chandramohan D, Issifou S, Mockenhaupt F, Owusu-Agyei S, Greenwood B, Grobusch MP, Kremsner PG, Macete E, Mshinda H, Newman RD, Slutsker L, Tanner M, Alonso P, Menendez C, 2009. Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials. Lancet 374: 15331542.

    • Search Google Scholar
    • Export Citation
  • 6.

    Gosling RD, Gesase S, Mosha JF, Carneiro I, Hashim R, Lemnge M, Mosha FW, Greenwood B, Chandramohan D, 2009. Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial. Lancet 374: 15211532.

    • Search Google Scholar
    • Export Citation
  • 7.

    O'Meara WP, Smith DL, McKenzie FE, 2006. Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malaria. PLoS Med 3: e141.

    • Search Google Scholar
    • Export Citation
  • 8.

    White NJ, 2005. Intermittent presumptive treatment for malaria. PLoS Med 2: e3.

  • 9.

    de Sousa A, Salama P, Chopra M, 2010. Implementing intermittent preventive treatment in infants. Lancet 375: 121.

  • 10.

    McGready R, 2009. Intermittent preventive treatment of malaria in infancy. Lancet 374: 14781480.

  • 11.

    Laufer MK, Thesing PC, Eddington ND, Masonga R, Dzinjalamala FK, Takala SL, Taylor TE, Plowe CV, 2006. Return of chloroquine antimalarial efficacy in Malawi. N Engl J Med 355: 19591966.

    • Search Google Scholar
    • Export Citation
 
 
 

 

 

 

 

 

 

Intermittent Preventive Treatment for Malaria in Sub-Saharan African: A Halfway Technology or a Critical Intervention?

View More View Less
  • Division of Infectious Diseases, Department of Medicine University of California San Diego, La Jolla, California

Author Notes

*Address correspondence to Joseph M. Vinetz, Division of Infectious Diseases, Department of Medicine, University of California San Diego, 9500 Gilman Drive 0741, George Palade Laboratories Room 125, La Jolla, CA 92093-0741. E-mail: jvinetz@ucsd.edu

Author's address: Joseph M. Vinetz, Division of Infectious Diseases, Department of Medicine, University of California San Diego, 9500 Gilman Drive 0741, George Palade Laboratories Room 125, La Jolla, CA 92093-0741, Tel: 1-858-822-4469, Fax: 1-858-822-5320, E-mail: jvinetz@ucsd.edu.

Save