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Novel Swine-Origin Influenza A (H1N1) Virus-Associated Hemophagocytic Syndrome—A First Case Report

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  • 1 Intensive Care Unit of Second Affiliated Hospital of Southeast University, Nanjing, China; Department of Respiratory Disease of Jiangsu Provincial People's Hospital, Nanjing, China

Secondary or reactive hemophagocytic syndrome (HPS) is frequently related to viral infections. However, the novel swine-origin influenza A (H1N1) virus associated HPS has never been reported. On October 10, 2009, a 17-year-old female child with no past medical history, complaining of severe asthenia, pneumonia, myalgia, and high fever, was admitted to our department, and H1N1 DNA was detected. Five days after her hospitalization, all signs and symptoms aggravated into HPS. After treatment for H1N1 influenza, the patient had a recovery and clearance of H1N1 infection 10 days after hospitalization. Three weeks later, the patient was discharged without any complaints, indicating the etiological role of H1N1infection in HPS.

Author Notes

*Address correspondence to Wei Zhao, ICU of Second Affiliated Hospital of Southeast University, Nanjing, 210003 China. E-mail: Doctor0219@163.com

Author's address: Wei Zhao, ICU of Second Affiliated Hospital of Southeast University, Nanjing, 210003 China, E-mail: Doctor0219@163.com.

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