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To elucidate the importance of the norovirus and other enteric viruses, and the difference of the genetic relatedness on norovirus between the outbreak and sporadic cases, a total of 557 stool samples, consisting of 503 sporadic cases and 54 samples of 4 outbreaks were collected and tested for norovirus and other enteric viruses in Beijing, China, July 2007–June 2008. The data showed norovirus, rotavirus, astrovirus, and sapovirus, were detected in 26.6%, 6.1%, 1.8%, and 0.5%, respectively. Norovirus was detected almost throughout the surveillance period, norovirus co-infecting with rotavirus, astrovirus, and sapovirus, respectively, were identified both in outbreak and the sporadic cases. GII.4/2006 was identified as the predominant strain circulating both in outbreak and sporadic cases. The results showed that norovirus was rather the important agent than other enteric viruses affected adults with acute gastroenteritis; no significant genetic relatedness of the dominant strains was found between the outbreak and sporadic cases.
Financial support: This study is supported by the National Science Fund for Distinguished Scholars of PR China (no. 30725032), National Nature and Science Foundation of the People's Republic of China (no. 30872150), and Special Grant for the Prevention and Control of Infection Diseases (no. 2009ZX10004-204).
Authors' addresses: Li-Juan Liu, Wei Liu, and Wu-Chun Cao, Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, People's Republic of China, E-mail: firstname.lastname@example.org. Yun-Xi Liu and Ning Jia, Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing 100853, People's Republic of China. Hong-Jv Xiao, Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing 100853, People's Republic of China. Yi-Gang Tong, Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, People's Republic of China.