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Leishmaniasis in the Tongue of an Immunocompetent Man

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  • 1 Department of Dermatology and Department of Medical Parasitology, Medical University of Vienna, Vienna, Austria
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A 49-year-old immunocompetent white man had a painful ulcer (1.5 cm in diameter) on the left ventrolateral surface of a grossly enlarged tongue. The ulcer was present for two months. Impaired swallowing resulted in substantial weight loss and fatigue. Histopathologic analysis of a punch biopsy specimen indicated numerous Leishman Donovan bodies within macrophages. A polymerase chain reaction confirmed the presence of L. donovani. Therapy with two cycles of liposomal amphotericin B over a three-month period was administered. Four months after discharge, the ulcer had healed completely and the tongue returned to its normal size and function.

Author Notes

*;Address correspondence to Jessika Weingast, Universitaetsklinik fuer Dermatologie, Abteilung fuer Allgemeine Dermatologie, Waehringer Guertel 18-20, A-1090 Vienna, Austria. E-mail: jessika.weingast@meduniwien.ac.at
†These authors contributed equally to this article.

Authors' addresses: Verena Leitner, Jessika Weingast, Kaan Harmankaya, Hubert Pehamberger, Peter Petztelbauer, and Michael Binder, Universitaetsklinik fuer Dermatologie, Abteilung fuer Allgemeine Dermatologie, Waehringer Guertel 18-20, A-1090 Vienna, Austria, E-mails: verena.leitner@meduniwien.ac.at, jessika.weingast@meduniwien.ac, kaan.harmankaya@meduniwien.ac, hubert.pehamberger@meduniwien.ac, peter.petzelbauer@meduniwien.ac, and michael.binder@meduniwien.ac. Julia Walochnik and Herbert Auer, Medizinische Universitaet Wien Institut fuer Medizinische Prophylaxe und Tropenmedizin, Kinderspitalgasse 15, A-1090 Vienna, Austria, E-mails: Julia.walochnik@meduniwien.ac and herbert.auer@meduniwien.ac.