Author:
ProCite
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Reference Manager
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EndNote
-
1.
Mendis K, Sina BJ, Marchesini P, Carter R, 2001, The neglected burden of Plasmodium vivax malaria. America. Am J Trop Med Hyg 64 (1–2 Suppl): 97–106.
-
2.
Price RN, Tjitra E, Guerra CA, Yeung S, White NJ, Anstey NM, 2007. Vivax malaria: neglected and not benign. Am J Trop Med Hyg 77 (Suppl): 79–87.
-
3.
Carlton JM, Adams JH, Silva JC, Bidwell SL, Lorenzi H, Caler E, Crabtree J, Angiuoli SV, Merino EF, Amedeo P, Cheng Q, Coulson RM, Crabb BS, Del Portillo HA, Essien K, Feldblyum TV, Fernandez-Becerra C, Gilson PR, Gueye AH, Guo X, Kang’a S, Kooij TW, Korsinczky M, Meyer EV, Nene V, Paulsen I, White O, Ralph SA, Ren Q, Sargeant TJ, Salzberg SL, Stoeckert CJ, Sullivan SA, Yamamoto MM, Hoffman SL, Wortman JR, Gardner MJ, Galinski MR, Barnwell JW, Fraser-Liggett CM, 2008. Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature 455: 757–763.
-
4.
Alam MZ, Kuhls K, Schweynoch C, Sundar S, Rijal S, Shamsuzzaman AK, Raju BV, Salotra P, Dujardin JC, Schönian G, 2008. Multilocus microsatellite typing (MLMT) reveals genetic homogeneity of Leishmania donovani strains in the Indian subcontinent. Infect Genet Evol 9: 24–31.
-
5.
Anderson TJ, Haubold B, Williams JT, Estrada-Franco JG, Richardson L, Mollinedo R, Bockarie M, Mokili J, Mharakurwa S, French N, Whitworth J, Velez ID, Brockman AH, Nosten F, Ferreira MU, Day KP, 2000. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol Biol Evol 17: 1467–1482.
-
6.
Karunaweera ND, Ferreira MU, Munasinghe A, Barnwell JW, Collins WE, King CL, Kawamoto F, Hartl DL, Wirth DF, 2008. Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene 410: 105–112.
-
7.
Imwong M, Nair S, Pukrittayakamee S, Sudimack D, Williams JT, Mayxay M, Newton PN, Kim JR, Nandy A, Osorio L, Carlton JM, White NJ, Day NP, Anderson TJ, 2007. Contrasting genetic structure in Plasmodium vivax populations from Asia and South America. Int J Parasitol 37: 1013–1022.
-
8.
Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, Guthmann JP, Nosten F, Carlton J, Looareesuwan S, Nair S, Sudimack D, Day NP, Anderson TJ, White NJ, 2007. Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. J Infect Dis 195: 927–933.
-
9.
Karunaweera ND, Ferreira MU, Hartl DL, Wirth DF, 2007. Fourteen polymorphic microsatellite DNA markers for the human malaria parasite Plasmodium vivax. Mol Ecol Notes 7: 172–175.
-
10.
Erhart A, Thang ND, Hung NQ, Toi le V, Hung le X, Tuy TQ, Cong le D, Speybroeck N, Coosemans M, D’Alessandro U, 2004. Forest malaria in Vietnam: a challenge for control. Am J Trop Med Hyg 70: 110–118.
-
11.
Benson G, 1999. Tandem repeats finder: a program to analyze DNA sequences tandem repeats finder: a program to analyze DNA sequences Nucleic Acids Res 27: 573–580.
-
12.
Genome of P. vivax. Available at: http://plasmodb.org/plasmo/showApplication.do. Accessed November 2005.
-
13.
Rubio JM, Post RJ, van Leeuwen WM, Henry MC, Lindergard G, Hommel M, 2002. Alternative polymerase chain reaction method to identify Plasmodium species in human blood samples: the semi-nested multiplex malaria PCR (SnM-PCR). Trans R Soc Trop Med Hyg 96 (Suppl 1): S199–S204.
-
14.
Plowe CV, Djimde A, Bouare M, Doumbo O, Wellems TE, 1995. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. Am J Trop Med Hyg 52: 565–568.
-
15.
Anderson TJ, Su XZ, Bockarie M, Lagog M, Day KP, 1999. Twelve microsatellite markers for characterization of Plasmodium falciparum from finger-prick blood samples. Parasitology 119: 113–125.
-
16.
Havryliuk T, Orjuela-Sánchez P, Ferreira MU, 2008. Plasmodium vivax: microsatellite analysis of multiple-clone infections. Exp Parasitol 120: 330–336.
-
17.
Havryliuk T, Ferreira MU, 2009. A closer look at multiple-clone Plasmodium vivax infections: detection methods, prevalence and consequences. Mem Inst Oswaldo Cruz 104: 67–73.
-
18.
Trung HD, Van Bortel W, Sochantha T, Keokenchanh K, Quang NT, Cong LD, Coosemans M, 2004. Malaria transmission and major malaria vectors in different geographical areas of southeast Asia. Trop Med Int Health 9: 230–237.
-
19.
Ferreira MU, Karunaweera ND, Silva-Nunes M, da Silva NS, Wirth DF, Hartl DL, 2007. Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia. J Infect Dis 195: 1218–1226.
-
20.
Chen N, Auliff A, Rieckmann K, Gatton M, Cheng Q, 2007. Relapses of Plasmodium vivax infection result from clonal hypnozoites activated at predetermined intervals. J Infect Dis 195: 934–941.
-
21.
Koepfli C, Mueller I, Marfurt J, Goroti M, Sie A, Oa O, Genton B, Beck HP, Felger I, 2009. Evaluation of Plasmodium vivax genotyping markers for molecular monitoring in clinical trials. J Infect Dis 199: 1074–1080.
-
22.
Rezende AM, Tarazona-Santos E, Couto AD, Fontes CJ, De Souza JM, Carvalho LH, Brito CF, 2009. Analysis of genetic variability of Plasmodium vivax isolates from different Brazilian Amazon areas using tandem repeats. Am J Trop Med Hyg 80: 729–733.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 37 | 37 | 6 |
| Full Text Views | 313 | 126 | 0 |
| PDF Downloads | 67 | 35 | 0 |
High Complexity of Plasmodium vivax Infections in Symptomatic Patients from a Rural Community in Central Vietnam Detected by Microsatellite Genotyping
Peter Van den Eede
Peter Van den Eede
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Annette Erhart
Annette Erhart
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Gert Van der Auwera
Gert Van der Auwera
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Chantal Van Overmeir
Chantal Van Overmeir
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Ngo Duc Thang
Ngo Duc Thang
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Le Xuan Hung
Le Xuan Hung
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Jozef Anné
Jozef Anné
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Umberto D’Alessandro
Umberto D’Alessandro
Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium; National Institute of Malariology, Parasitology, and Entomology, Hanoi, Vietnam; Laboratory of Bacteriology, Katholieke Universiteit Leuven, Leuven, Belgium
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Fourteen published and three newly identified polymorphic microsatellites were used to genotype 69 Plasmodium vivax samples obtained from 39 patients detected over a period of two years who lived in a rural community of central Vietnam. All samples were polyclonal with an average expected heterozygosity of 0.86. Among the 39 patients, 16 experienced 1–5 recurrent episodes of P. vivax malaria, most of them (83%) with a different genotype profile compared with previous infections. The minimal set of microsatellites required for differentiating the genotype profiles of the recurrent infections compared with the full set of 17 microsatellites was explored. A combination of five markers was sufficient to identify all recurrent infections with an unrelated or different genotype profile compared with all previous episodes.
Author Notes
Financial support: This study was supported by the Flemish government funds (Fonds voor Wetenschappelijk Onderzoek) and the Institute for the Promotion of Innovation by Science, and Technology in Flanders (PhD grant). The field study in Vietnam was supported by the Framework Agreement 2 between the Institute of Tropical Medicine Antwerp, and the Belgian Technical Cooperation.
Authors' addresses: Peter Van den Eede, Annette Erhart, Gert Van der Auwera, Chantal Van Overmeir, and Umberto D'Alessandro, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium, E-mails: pvandeneede@itg.be, aerhart@itg.be, gvdauwera@itg.be, cvovermeir@itg.be, and udalessandro@itg.be. Ngo Duc Thang and Le Xuan Hung, National Institute of Malariology, Parasitology and Entomology, BC 10200 Tu Liem District, Hanoi, Vietnam, E-mails: thangnimpevn@yahoo.com and lxhung1952@yahoo.com. Jozef Anné, Laboratory of Bacteriology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium, E-mail: jozef.anne@rega.kuleuven.be.
Reprint requests: Peter Van den Eede, Department of Parasitology, Institute of Tropical Medicine Antwerp, Nationalestraat 155 Antwerp, Belgium, E-mail: pvandeneede@itg.be.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Mendis K, Sina BJ, Marchesini P, Carter R, 2001, The neglected burden of Plasmodium vivax malaria. America. Am J Trop Med Hyg 64 (1–2 Suppl): 97–106.
-
2.
Price RN, Tjitra E, Guerra CA, Yeung S, White NJ, Anstey NM, 2007. Vivax malaria: neglected and not benign. Am J Trop Med Hyg 77 (Suppl): 79–87.
-
3.
Carlton JM, Adams JH, Silva JC, Bidwell SL, Lorenzi H, Caler E, Crabtree J, Angiuoli SV, Merino EF, Amedeo P, Cheng Q, Coulson RM, Crabb BS, Del Portillo HA, Essien K, Feldblyum TV, Fernandez-Becerra C, Gilson PR, Gueye AH, Guo X, Kang’a S, Kooij TW, Korsinczky M, Meyer EV, Nene V, Paulsen I, White O, Ralph SA, Ren Q, Sargeant TJ, Salzberg SL, Stoeckert CJ, Sullivan SA, Yamamoto MM, Hoffman SL, Wortman JR, Gardner MJ, Galinski MR, Barnwell JW, Fraser-Liggett CM, 2008. Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature 455: 757–763.
-
4.
Alam MZ, Kuhls K, Schweynoch C, Sundar S, Rijal S, Shamsuzzaman AK, Raju BV, Salotra P, Dujardin JC, Schönian G, 2008. Multilocus microsatellite typing (MLMT) reveals genetic homogeneity of Leishmania donovani strains in the Indian subcontinent. Infect Genet Evol 9: 24–31.
-
5.
Anderson TJ, Haubold B, Williams JT, Estrada-Franco JG, Richardson L, Mollinedo R, Bockarie M, Mokili J, Mharakurwa S, French N, Whitworth J, Velez ID, Brockman AH, Nosten F, Ferreira MU, Day KP, 2000. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol Biol Evol 17: 1467–1482.
-
6.
Karunaweera ND, Ferreira MU, Munasinghe A, Barnwell JW, Collins WE, King CL, Kawamoto F, Hartl DL, Wirth DF, 2008. Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene 410: 105–112.
-
7.
Imwong M, Nair S, Pukrittayakamee S, Sudimack D, Williams JT, Mayxay M, Newton PN, Kim JR, Nandy A, Osorio L, Carlton JM, White NJ, Day NP, Anderson TJ, 2007. Contrasting genetic structure in Plasmodium vivax populations from Asia and South America. Int J Parasitol 37: 1013–1022.
-
8.
Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JR, Nandy A, Guthmann JP, Nosten F, Carlton J, Looareesuwan S, Nair S, Sudimack D, Day NP, Anderson TJ, White NJ, 2007. Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. J Infect Dis 195: 927–933.
-
9.
Karunaweera ND, Ferreira MU, Hartl DL, Wirth DF, 2007. Fourteen polymorphic microsatellite DNA markers for the human malaria parasite Plasmodium vivax. Mol Ecol Notes 7: 172–175.
-
10.
Erhart A, Thang ND, Hung NQ, Toi le V, Hung le X, Tuy TQ, Cong le D, Speybroeck N, Coosemans M, D’Alessandro U, 2004. Forest malaria in Vietnam: a challenge for control. Am J Trop Med Hyg 70: 110–118.
-
11.
Benson G, 1999. Tandem repeats finder: a program to analyze DNA sequences tandem repeats finder: a program to analyze DNA sequences Nucleic Acids Res 27: 573–580.
-
12.
Genome of P. vivax. Available at: http://plasmodb.org/plasmo/showApplication.do. Accessed November 2005.
-
13.
Rubio JM, Post RJ, van Leeuwen WM, Henry MC, Lindergard G, Hommel M, 2002. Alternative polymerase chain reaction method to identify Plasmodium species in human blood samples: the semi-nested multiplex malaria PCR (SnM-PCR). Trans R Soc Trop Med Hyg 96 (Suppl 1): S199–S204.
-
14.
Plowe CV, Djimde A, Bouare M, Doumbo O, Wellems TE, 1995. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. Am J Trop Med Hyg 52: 565–568.
-
15.
Anderson TJ, Su XZ, Bockarie M, Lagog M, Day KP, 1999. Twelve microsatellite markers for characterization of Plasmodium falciparum from finger-prick blood samples. Parasitology 119: 113–125.
-
16.
Havryliuk T, Orjuela-Sánchez P, Ferreira MU, 2008. Plasmodium vivax: microsatellite analysis of multiple-clone infections. Exp Parasitol 120: 330–336.
-
17.
Havryliuk T, Ferreira MU, 2009. A closer look at multiple-clone Plasmodium vivax infections: detection methods, prevalence and consequences. Mem Inst Oswaldo Cruz 104: 67–73.
-
18.
Trung HD, Van Bortel W, Sochantha T, Keokenchanh K, Quang NT, Cong LD, Coosemans M, 2004. Malaria transmission and major malaria vectors in different geographical areas of southeast Asia. Trop Med Int Health 9: 230–237.
-
19.
Ferreira MU, Karunaweera ND, Silva-Nunes M, da Silva NS, Wirth DF, Hartl DL, 2007. Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia. J Infect Dis 195: 1218–1226.
-
20.
Chen N, Auliff A, Rieckmann K, Gatton M, Cheng Q, 2007. Relapses of Plasmodium vivax infection result from clonal hypnozoites activated at predetermined intervals. J Infect Dis 195: 934–941.
-
21.
Koepfli C, Mueller I, Marfurt J, Goroti M, Sie A, Oa O, Genton B, Beck HP, Felger I, 2009. Evaluation of Plasmodium vivax genotyping markers for molecular monitoring in clinical trials. J Infect Dis 199: 1074–1080.
-
22.
Rezende AM, Tarazona-Santos E, Couto AD, Fontes CJ, De Souza JM, Carvalho LH, Brito CF, 2009. Analysis of genetic variability of Plasmodium vivax isolates from different Brazilian Amazon areas using tandem repeats. Am J Trop Med Hyg 80: 729–733.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 37 | 37 | 6 |
| Full Text Views | 313 | 126 | 0 |
| PDF Downloads | 67 | 35 | 0 |