ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
De Silva A, Muddu A, Iredale J, Sheron N, Khakoo S, Pelosi E, 2008. Unexpectedly high incidence of indigenous acute hepatitis E within South Hampshire: time for routine testing? J Med Virol 80: 283–288.
-
2.
Teo C, 2006. Hepatitis E indigenous to economically developed countries: to what extent a zoonosis? Curr Opin Infect Dis 19: 460–466.
-
3.
Pina S, Buti M, Cotrina M, Piella J, Girones R, 2000. HEV identified in serum from humans with acute hepatitis and in sewage of animal origin in Spain. J Hepatol 33: 826–833.
-
4.
Jimenez de Oya N, Escribano-Romero E, Blazquez A, Saiz JC, 2007. El virus de la hepatitis E: implicaciones zoonóticas. Gastroenterol Hepatol 30: 408–418.
-
5.
Fernández-Barredo S, Galiana C, Garcia A, Vega S, Gómez MT, Perez-Gracia MT, 2007. Prevalence and genetic characterization of hepatitis E virus (HEV) in paired samples of feces and serum from naturally infected pigs. Can J Vet Res 71: 236–242.
-
6.
Mateos ML, Molina A, Ta H, Moreira V, Milicia JM, Barcena R, 2006. Hepatitis aguda E en Madrid: a propósito de 18 casos. Gastroenterol Hepatol 29: 395–398.
-
7.
Perez-Gracia MT, Garcia-Valdivia MS, Galan F, Rodriguez-Iglesias MA, 2004. Detection of hepatitis E virus in patients sera in southern Spain. Acta Virol 48: 197–200.
-
8.
Perez-Gracia MT, Mateos ML, Galiana C, Fernández-Barredo S, García A, Gómez MT, Moreira V, 2007. Autochthonous hepatitis E infection in a slaughterhouse worker. Am J Trop Med Hyg 77: 893–896 .
-
9.
Galiana C, Fernández-Barredo S, García A, Gómez MT, Pérez-Gracia MT, 2008. Occupational exposure to hepatitis E virus (HEV) in swine workers. Am J Trop Med Hyg 78: 1012–1015.
-
10.
Dalton H, Bendall R, Ijaz S, Banks M, 2008. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis 8: 698–709.
-
11.
Mushahwar I, Hepatitis E, 2008. Virus: molecular virology, clinical features, diagnosis, transmission, epidemiology and prevention. J Med Virol 80: 646–658.
-
12.
Jaiswal SP, Jain AK, Naik G, Soni K, Chitnis DS, 2001. Viral hepatitis during pregnancy. J Gynaecol Obstetr 72: 103–108.
-
13.
Patra S, Kumar A, Trivedi SS, Puri M, Sarin SK, 2007. Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection. Ann Intern Med 147: 28–33.
-
14.
Jilani N, Das BC, Husain SA, Baweja UK, Chattopadhya D, Gupta RK, Sardana S, Kar P, 2007. Hepatitis E virus infection and fulminant hepatic failure during pregnancy. J Gastroenterol Hepatol 22: 676–682.
-
15.
Fernández Barredo S, Galiana C, Garcia A, Vega S, Gómez MT, Perez Gracia MT, 2006. Detection of hepatitis E virus shedding in feces of pigs at different stages of production using reverse transcription-polymerase chain reaction. J Vet Diagn Invest 18: 462–465.
-
16.
Zijlstra JG, Haagsma EB, Tulleken JE, van der Werf TS, 1997. Hepatitis-E-associated fulminant hepatic failure in non-pregnant young women. Lancet 350: 289–290.
-
17.
Lu L, Li C, Hagedorn CH, 2006. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol 16: 5–36.
-
18.
Kamar N, Selves J, Mansuy JM, Ouezzani L, Peron JM, Guitard J, Cointault O, Esposito L, Abravanel F, Danjoux M, Durand D, Vinel JP, Izopet K, Rostaing L, 2008. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med 358: 811–817.
-
19.
Ramachandran J, Ramakrishna B, Eapen C, Abraham P, Zacharuah U, Jayram A, Kuriam G, Mukopadhya A, Chandy G, 2008. Subacute hepatic failure due to hepatitis E. J Gastroenterol Hepatol 23: 879–882.
-
20.
Navaneethan U, Al Mohajer M, Shata MT, 2008. Hepatitis E and pregnancy: understanding the pathogenesis. Liver Int 28: 1190–1199.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 537 | 434 | 309 |
| Full Text Views | 285 | 4 | 0 |
| PDF Downloads | 74 | 6 | 0 |
Fulminant Hepatitis E in a Woman Taking Oral Contraceptive Medication
Maria Luisa Mateos Lindemann
Maria Luisa Mateos Lindemann
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Maria Luisa Mateos Lindemann in
Current site
Google Scholar
PubMed
Search for other papers by Maria Luisa Mateos Lindemann in
Current site
Google Scholar
PubMed
Javier Graus Morales
Javier Graus Morales
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Javier Graus Morales in
Current site
Google Scholar
PubMed
Search for other papers by Javier Graus Morales in
Current site
Google Scholar
PubMed
Salceda Fernández-Barredo
Salceda Fernández-Barredo
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Salceda Fernández-Barredo in
Current site
Google Scholar
PubMed
Search for other papers by Salceda Fernández-Barredo in
Current site
Google Scholar
PubMed
Mario Rodríguez Domínguez
Mario Rodríguez Domínguez
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Mario Rodríguez Domínguez in
Current site
Google Scholar
PubMed
Search for other papers by Mario Rodríguez Domínguez in
Current site
Google Scholar
PubMed
Fernando García de la Hoz
Fernando García de la Hoz
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Fernando García de la Hoz in
Current site
Google Scholar
PubMed
Search for other papers by Fernando García de la Hoz in
Current site
Google Scholar
PubMed
Philippe Halfon
Philippe Halfon
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Philippe Halfon in
Current site
Google Scholar
PubMed
Search for other papers by Philippe Halfon in
Current site
Google Scholar
PubMed
Maria Teresa Pérez Gracia
Maria Teresa Pérez Gracia
Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain; Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France; Microbiology, CEU Cardenal Herrera University, Moncada, Valencia, Spain
Search for other papers by Maria Teresa Pérez Gracia in
Current site
Google Scholar
PubMed
Search for other papers by Maria Teresa Pérez Gracia in
Current site
Google Scholar
PubMed
We describe a fulminant autochthonous hepatic failure caused by hepatitis E (HEV) in a patient admitted in our hospital for liver-transplant evaluation. The only risk factor recorded for this severe course was the use of oral contraceptives that are known to mimic a hormonal status similar to pregnancy. The diagnosis was based on the presence of IgG and IgM anti-HEV in the serum of the patient and confirmed by the isolation of a strain of HEV genotype 3f from a blood sample obtained the fourth day after hospital admission. HEV genotype 3 is present in human and swine populations in Spain. The patient began to recover while waiting for a liver transplant. To our knowledge, this is the first report of fulminant hepatitis E in a non-pregnant European patient on oral contraceptives.
Author Notes
Authors' addresses: Maria Luisa Mateos Lindemann and Mario Rodríguez Domínguez, Microbiology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain. Javier Graus Morales and Fernando García de la Hoz, Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain. Salceda Fernández-Barredo and Maria Teresa Pérez Gracia, Microbiology, CEU Cardenal Herrera University Moncada, Valencia, Spain. Philippe Halfon, Laboratoire ALPHABIO, Hopital Ambroise Paré, Marseille, France.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
De Silva A, Muddu A, Iredale J, Sheron N, Khakoo S, Pelosi E, 2008. Unexpectedly high incidence of indigenous acute hepatitis E within South Hampshire: time for routine testing? J Med Virol 80: 283–288.
-
2.
Teo C, 2006. Hepatitis E indigenous to economically developed countries: to what extent a zoonosis? Curr Opin Infect Dis 19: 460–466.
-
3.
Pina S, Buti M, Cotrina M, Piella J, Girones R, 2000. HEV identified in serum from humans with acute hepatitis and in sewage of animal origin in Spain. J Hepatol 33: 826–833.
-
4.
Jimenez de Oya N, Escribano-Romero E, Blazquez A, Saiz JC, 2007. El virus de la hepatitis E: implicaciones zoonóticas. Gastroenterol Hepatol 30: 408–418.
-
5.
Fernández-Barredo S, Galiana C, Garcia A, Vega S, Gómez MT, Perez-Gracia MT, 2007. Prevalence and genetic characterization of hepatitis E virus (HEV) in paired samples of feces and serum from naturally infected pigs. Can J Vet Res 71: 236–242.
-
6.
Mateos ML, Molina A, Ta H, Moreira V, Milicia JM, Barcena R, 2006. Hepatitis aguda E en Madrid: a propósito de 18 casos. Gastroenterol Hepatol 29: 395–398.
-
7.
Perez-Gracia MT, Garcia-Valdivia MS, Galan F, Rodriguez-Iglesias MA, 2004. Detection of hepatitis E virus in patients sera in southern Spain. Acta Virol 48: 197–200.
-
8.
Perez-Gracia MT, Mateos ML, Galiana C, Fernández-Barredo S, García A, Gómez MT, Moreira V, 2007. Autochthonous hepatitis E infection in a slaughterhouse worker. Am J Trop Med Hyg 77: 893–896 .
-
9.
Galiana C, Fernández-Barredo S, García A, Gómez MT, Pérez-Gracia MT, 2008. Occupational exposure to hepatitis E virus (HEV) in swine workers. Am J Trop Med Hyg 78: 1012–1015.
-
10.
Dalton H, Bendall R, Ijaz S, Banks M, 2008. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis 8: 698–709.
-
11.
Mushahwar I, Hepatitis E, 2008. Virus: molecular virology, clinical features, diagnosis, transmission, epidemiology and prevention. J Med Virol 80: 646–658.
-
12.
Jaiswal SP, Jain AK, Naik G, Soni K, Chitnis DS, 2001. Viral hepatitis during pregnancy. J Gynaecol Obstetr 72: 103–108.
-
13.
Patra S, Kumar A, Trivedi SS, Puri M, Sarin SK, 2007. Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection. Ann Intern Med 147: 28–33.
-
14.
Jilani N, Das BC, Husain SA, Baweja UK, Chattopadhya D, Gupta RK, Sardana S, Kar P, 2007. Hepatitis E virus infection and fulminant hepatic failure during pregnancy. J Gastroenterol Hepatol 22: 676–682.
-
15.
Fernández Barredo S, Galiana C, Garcia A, Vega S, Gómez MT, Perez Gracia MT, 2006. Detection of hepatitis E virus shedding in feces of pigs at different stages of production using reverse transcription-polymerase chain reaction. J Vet Diagn Invest 18: 462–465.
-
16.
Zijlstra JG, Haagsma EB, Tulleken JE, van der Werf TS, 1997. Hepatitis-E-associated fulminant hepatic failure in non-pregnant young women. Lancet 350: 289–290.
-
17.
Lu L, Li C, Hagedorn CH, 2006. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol 16: 5–36.
-
18.
Kamar N, Selves J, Mansuy JM, Ouezzani L, Peron JM, Guitard J, Cointault O, Esposito L, Abravanel F, Danjoux M, Durand D, Vinel JP, Izopet K, Rostaing L, 2008. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med 358: 811–817.
-
19.
Ramachandran J, Ramakrishna B, Eapen C, Abraham P, Zacharuah U, Jayram A, Kuriam G, Mukopadhya A, Chandy G, 2008. Subacute hepatic failure due to hepatitis E. J Gastroenterol Hepatol 23: 879–882.
-
20.
Navaneethan U, Al Mohajer M, Shata MT, 2008. Hepatitis E and pregnancy: understanding the pathogenesis. Liver Int 28: 1190–1199.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 537 | 434 | 309 |
| Full Text Views | 285 | 4 | 0 |
| PDF Downloads | 74 | 6 | 0 |