Crimean-Congo Hemorrhagic Fever Virus as a Nosocomial Pathogen in Iran

Masoud Mardani Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University, Tehran, Iran; Clinical Research and Development Center, Shahid Modarres Hospital, Tehran, Iran; Infectious Diseases Research Center, and Division of Gastroenterology, Department of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

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Maryam Keshtkar-Jahromi Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University, Tehran, Iran; Clinical Research and Development Center, Shahid Modarres Hospital, Tehran, Iran; Infectious Diseases Research Center, and Division of Gastroenterology, Department of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

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Behrooz Ataie Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University, Tehran, Iran; Clinical Research and Development Center, Shahid Modarres Hospital, Tehran, Iran; Infectious Diseases Research Center, and Division of Gastroenterology, Department of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

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Peyman Adibi Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University, Tehran, Iran; Clinical Research and Development Center, Shahid Modarres Hospital, Tehran, Iran; Infectious Diseases Research Center, and Division of Gastroenterology, Department of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

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Crimean-Congo hemorrhagic fever (CCHF) is a viral disease with several different modes of transmission. We describe the manifestations, outcome, and likely modes of transmission for three nosocomial cases. All threee cases were healthcare workers (two men and one woman). They had fever, myalgia, and petechia. Disseminated intravascular coagulation resulted in the death occurred in the woman. Because this disease is manifested with non-specific influenza-like symptoms, diagnosis can be difficult. Data for these patients can be used to investigate airborne or sexual transmission of this virus, although neither route was substantiated for these patients. Use of universal precautions and early case detection are the most helpful strategy for preventing nosocomial transmission of CCHF.

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