• 1

    Chen SM, Dumler JS, Bakken JS, Walker DH, 1994. Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J Clin Microbiol 32 :589–595.

    • Search Google Scholar
    • Export Citation
  • 2

    Centers for Disease Control and Prevention, 2008. Tickborne Rickettsial Diseases. Available at: http://www.cdc.gov/ticks/index.html. Accessed December 20, 2008.

  • 3

    Petrovec M, Lotric FS, Zupanc TA, Strle F, Brouqui P, Roux V, Dumler JS, 1997. Human disease in Europe caused by a granulocytic Ehrlichia species. J Clin Microbiol 35 :1556–1559.

    • Search Google Scholar
    • Export Citation
  • 4

    Keysary A, Massung RF, Inbar M, Wallach AD, Shanas U, Mumcuoglu KY, Waner T, 2007. Molecular evidence for Anaplasma phagocytophilum in Israel. Emerg Infect Dis 13 :1411–1412.

    • Search Google Scholar
    • Export Citation
  • 5

    Ohashi N, Inayoshi M, Kitamura K, Kawamori F, Kawaguchi D, Nishimura Y, Naitou H, Hiroi M, Masuzawa T, 2005. Anaplasma phagocytophilum-infected ticks, Japan. Emerg Infect Dis 11 :1780–1783.

    • Search Google Scholar
    • Export Citation
  • 6

    Cao WC, Zhao QM, Zhang PH, Dumler JS, Zhang XT, Fang LQ, Yang H, 2000. Granulocytic Ehrlichiae in Ixodes persulcatus ticks from an area in China where Lyme disease is endemic. J Clin Microbiol 38 :4208–4210.

    • Search Google Scholar
    • Export Citation
  • 7

    Zhang L, Liu Y, Ni D, Li Q, Yu Y, Yu XJ, Wan K, Li D, Liang G, Jiang X, Jing H, Run J, Luan M, Fu X, Zhang J, Yang W, Wang Y, Dumler JS, Feng Z, Ren J, Xu J, 2008. Nosocomial transmission of human granulocytic anaplasmosis in China. JAMA 300 :2263–2270.

    • Search Google Scholar
    • Export Citation
  • 8

    Schauber EM, Gertz SJ, Maple WT, Ostfeld RS, 1998. Coinfection of blacklegged ticks (Acari: Ixodidae) in Dutchess County, New York, with the agents of Lyme disease and human granulocytic ehrlichiosis. J Med Entomol 35 :901–903.

    • Search Google Scholar
    • Export Citation
  • 9

    Stanczak J, Gabre RM, Kruminis-Lozowska W, Racewicz M, Kubica-Biernat B, 2004. Ixodes ricinus as a vector of Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti in urban and suburban forests. Ann Agric Environ Med 11 :109–114.

    • Search Google Scholar
    • Export Citation
  • 10

    Liu M, Che D, Huang K, 1996. Tick species and the key for identification of Ixodoidea tick in Shanxi. J Shanxi Normal Univ 10 :35–38.

    • Search Google Scholar
    • Export Citation
  • 11

    Liu M, Wu Y, 1995. Investigation of ticks and tick-bites in Pangquangou natural reservation. J Changzhi Medical College 9 :199–200.

    • Search Google Scholar
    • Export Citation
  • 12

    Liu M, Wu Y, Zhao Z, 2006. Preliminary investigation of Lyme disease serology of patients in Changzhi, Shanxi Province. J Changzhi Medical College 20 :17–18.

    • Search Google Scholar
    • Export Citation
  • 13

    Chen Z, Pan L, Song X, Bi D, Wang H, 1997. An investigation of vector and host animal of SFG and Lyme disease in Ninghua County of Fujian Provice. Chin J Vector Biol Control 8 :215.

    • Search Google Scholar
    • Export Citation
  • 14

    Luo HL, Pan L, and Yu SC, 1994. The report of four cases of Lyme disease in Wuyi Mountain area. Chin J Zoonoses 10 :40.

  • 15

    Liu MS, Wu YY, Zhao ZF, 2006. Seroepidemiologic study of Lyme disease in Shanxi Province. J Changzhi Medical College 20 :17–18.

  • 16

    Zhan L, He J, Saren GW, Wu XM, Wang JB, Zhao QM, Zhang PH, Huang HN, Jiang BG, Jiang JF, Zhang JB, Chu CY, Gao Y, Yang H, Cao WC, 2007. Investigation on Anaplasma phagocytophilum infection in rodents from forest areas in northeastern China. Chin J Epidemiol 28 :157–159.

    • Search Google Scholar
    • Export Citation
  • 17

    Zhang L, Shan A, Mathew B, Yin J, Fu X, Zhang J, Lu J, Xu J, Dumler JS, 2008. Rickettsial seroepidemiology among farm workers, Tianjin, People’s Republic of China. Emerg Infect Dis 14 :938–940.

    • Search Google Scholar
    • Export Citation
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Seroprevalence of Human Granulocytotropic Anaplasmosis in Central and Southeastern China

Shouyin ZhangState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Rong HaiState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Wenyuan LiState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Guohua LiState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Guangyu LinState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Jinrong HeState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Xiuping FuState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Jingshan ZhangState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Hong CaiState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Fengqin MaState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Jianhua ZhangState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Dongzheng YuState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Xue-jie YuState Key Lab for Infectious Diseases Prevention and Control, National Institute for Communicable Diseases Prevention and Control, Chinese Centers for Disease Control and Prevention, Beijing, China; Shanxi Provincial Centers for Disease Control and Prevention, Taiyuan, China; Nanping City Centers for Disease Control and Prevention of Fujian Province, Nanping, China; Department of Pathology, University of Texas Medical Branch, Galveston, Texas

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Human granulocytic anaplasmosis (HGA) is an emerging tick-borne infectious disease. To determine the prevalence of HGA in central and southeastern China, a total of 323 human sera were collected from individuals at high risk for exposure to ticks and animals. The IgG antibody against the etiologic agent of HGA, Anaplasma phagocytophilum was detected with indirect immunofluorescence assay. The results showed that 20% of the tested individuals (64/323) were positive to A. phagocytophilum and that the incidence was higher in male (22%) than female (16%). We concluded that A. phagocytophilum infection was prevalent in central and southeastern China.

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