The Effects of Sustained Release Metofluthrin on the Biting, Movement, and Mortality of Aedes aegypti in a Domestic Setting

Luke P. Rapley School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Queensland, Australia; Department of Medical Entomology, University of Sydney, Westmead Hospital, Westmead, NSW, Australia; Tropical Population Health Services, Queensland Health, Cairns, Queensland, Australia; School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Australia

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Richard C. Russell School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Queensland, Australia; Department of Medical Entomology, University of Sydney, Westmead Hospital, Westmead, NSW, Australia; Tropical Population Health Services, Queensland Health, Cairns, Queensland, Australia; School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Australia

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Brian L. Montgomery School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Queensland, Australia; Department of Medical Entomology, University of Sydney, Westmead Hospital, Westmead, NSW, Australia; Tropical Population Health Services, Queensland Health, Cairns, Queensland, Australia; School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Australia

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Scott A. Ritchie School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Queensland, Australia; Department of Medical Entomology, University of Sydney, Westmead Hospital, Westmead, NSW, Australia; Tropical Population Health Services, Queensland Health, Cairns, Queensland, Australia; School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, Australia

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The impact of a sustained release metofluthrin emanator and an allethrin-based mosquito coil on biting, movement and mortality of female Aedes aegypti was assessed in an apartment. In the room in which the metofluthrin emanator was activated, mosquito biting counts were reduced to zero. Metofluthrin also had a spillover effect, significantly (P < 0.001) reducing biting counts in a neighboring room 1, 4, and 24 hours after the emanator was activated when compared with either the coil or control (untreated) treatment. Mosquitoes were neither repelled nor expelled from a room exposed to metofluthrin. Indeed, a significantly (P = 0.023) greater proportion of mosquitoes were found in the treated room after exposure to metofluthrin when compared with either the coil or control treatment. Furthermore, in the room treated with metofluthrin the majority of mosquitoes died and a spillover effect into the neighboring room caused greater than one-third mortality of the mosquitoes. Metofluthrin could be used to prevent dengue transmission within a household.

Author Notes

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